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The map label for this gene is mdtN [H]

Identifier: 73541428

GI number: 73541428

Start: 1879980

End: 1881125

Strand: Reverse

Name: mdtN [H]

Synonym: Reut_A1739

Alternate gene names: 73541428

Gene position: 1881125-1879980 (Counterclockwise)

Preceding gene: 73541429

Following gene: 73541427

Centisome position: 49.42

GC content: 67.89

Gene sequence:

>1146_bases
ATGAGTGACGACGCGCCACCCGCCCCGGTATCTCCGCCCCCGGCGCCCGCGCCATCGCCAACGCCATCTCCCTCGGCAGA
TCCGGCCGGAAAGGGCGTAAAGGTGGTGGTGGTGCTGATCGTGCTGAGCCTGGCCTGGTACTTGTTCGCGGACCGTTATA
CGCCCTACACACAGCAGGCGCGCGTCCAGGCCTTTGTCGTGCCGGTGGCATCGGAGGTTTCGGGCCGCGTGACGCGTGTG
CTGGTGCACAACAACCAGGACGTGCAGGCGGGAGCGGTCCTGTTCGAGGTCGATCCGCAGCAATACCGCATCGCGGCCGA
TCGGGCGCGCGCGGACCTGGAATCCATGCGCCGGCAGATCGGTGCGAGCACGGCCGGGATCGCCTCGGCTCAGGCCGGGC
TGCGCGCCGCGCAGGCCAACGAGGTCAAGGCGCGCCAGGACAGTGACCGCCTGGAACGCCTGTATAGCGAGGATCCCGGC
ACTGTCTCGCTGAGGCGGCTCGAGGTGGCGCGCGCCACGCATACGCAGGCCGTCAGCCAGGTCGACGCAGCCCGCGCCGA
GGTGGTACGCGCGCGCGAGCAGCAGGGCGGCAGCGAAGAGGACAACGCCAAGTTACGCAGCTCCGCCGCGGCGCTGGAGA
AGGCCGAACTGGATCTCGCCAACTCCCGGGTCCGCGCTCGCATCGCTGGCCTCATCACCGATCTGCGCACGGAAGCGGGC
CAGTATGCCGCGGCAGGCAGCCCCGTCATGACGCTGATCGCGATTCATGACATCTGGATCAGTGCGGACATGACCGAAAA
CAATCTTGGCCGCGTCGAGCCAGGTACCCCAGTGGGAATCGTGCTCGATGCCTTGCCGGGCAGGGTACTTTCCGGCCGGG
TGCGCAGCATCGGCTATGGGGTGAGCGTCGGCCAGAGTCCGCCACCGGGCAGCCTGCCGACCGTCCAGAACAGCCGCGAC
TGGCTGCGTCCGGCCCAGCGGTTTCCGGTGATCGTCGAGATCGACAAGGGGGAACTGACGACGCTGCGGGGTGTCCGCGT
AGGCGGGCAAGCCGAGGTGATGGCCTTCCCGACCGATGGCAATCCGCTCAACCCGCTCGGCCGGATATTCCTGCACCTGA
TGAGCTGGCTGTCCTATGTCTACTGA

Upstream 100 bases:

>100_bases
CGGCAGCAGATGGAGCAACGTACCGACTGGGGCGGCCTGCTCGACGAGACGGTGAACGCTACAACCGGCAAACGCTCTTC
CTTGCAGCGAGGCACACCCA

Downstream 100 bases:

>100_bases
TGGCGGTGCGGCCAGCGCGGCAGGCATCCGCGGGCGGCGAGCGCTGCGGCTGGCCATCGGTACAGCAATCTGCCTGGCGA
CGAGCTTCGGCCTTGGCTGG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSDDAPPAPVSPPPAPAPSPTPSPSADPAGKGVKVVVVLIVLSLAWYLFADRYTPYTQQARVQAFVVPVASEVSGRVTRV
LVHNNQDVQAGAVLFEVDPQQYRIAADRARADLESMRRQIGASTAGIASAQAGLRAAQANEVKARQDSDRLERLYSEDPG
TVSLRRLEVARATHTQAVSQVDAARAEVVRAREQQGGSEEDNAKLRSSAAALEKAELDLANSRVRARIAGLITDLRTEAG
QYAAAGSPVMTLIAIHDIWISADMTENNLGRVEPGTPVGIVLDALPGRVLSGRVRSIGYGVSVGQSPPPGSLPTVQNSRD
WLRPAQRFPVIVEIDKGELTTLRGVRVGGQAEVMAFPTDGNPLNPLGRIFLHLMSWLSYVY

Sequences:

>Translated_381_residues
MSDDAPPAPVSPPPAPAPSPTPSPSADPAGKGVKVVVVLIVLSLAWYLFADRYTPYTQQARVQAFVVPVASEVSGRVTRV
LVHNNQDVQAGAVLFEVDPQQYRIAADRARADLESMRRQIGASTAGIASAQAGLRAAQANEVKARQDSDRLERLYSEDPG
TVSLRRLEVARATHTQAVSQVDAARAEVVRAREQQGGSEEDNAKLRSSAAALEKAELDLANSRVRARIAGLITDLRTEAG
QYAAAGSPVMTLIAIHDIWISADMTENNLGRVEPGTPVGIVLDALPGRVLSGRVRSIGYGVSVGQSPPPGSLPTVQNSRD
WLRPAQRFPVIVEIDKGELTTLRGVRVGGQAEVMAFPTDGNPLNPLGRIFLHLMSWLSYVY
>Mature_380_residues
SDDAPPAPVSPPPAPAPSPTPSPSADPAGKGVKVVVVLIVLSLAWYLFADRYTPYTQQARVQAFVVPVASEVSGRVTRVL
VHNNQDVQAGAVLFEVDPQQYRIAADRARADLESMRRQIGASTAGIASAQAGLRAAQANEVKARQDSDRLERLYSEDPGT
VSLRRLEVARATHTQAVSQVDAARAEVVRAREQQGGSEEDNAKLRSSAAALEKAELDLANSRVRARIAGLITDLRTEAGQ
YAAAGSPVMTLIAIHDIWISADMTENNLGRVEPGTPVGIVLDALPGRVLSGRVRSIGYGVSVGQSPPPGSLPTVQNSRDW
LRPAQRFPVIVEIDKGELTTLRGVRVGGQAEVMAFPTDGNPLNPLGRIFLHLMSWLSYVY

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=290, Percent_Identity=33.1034482758621, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790012, Length=345, Percent_Identity=28.695652173913, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790024, Length=348, Percent_Identity=28.448275862069, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87081951, Length=320, Percent_Identity=27.5, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789637, Length=315, Percent_Identity=27.6190476190476, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1789041, Length=335, Percent_Identity=24.7761194029851, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788711, Length=310, Percent_Identity=24.8387096774194, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40770; Mature: 40638

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDAPPAPVSPPPAPAPSPTPSPSADPAGKGVKVVVVLIVLSLAWYLFADRYTPYTQQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHC
RVQAFVVPVASEVSGRVTRVLVHNNQDVQAGAVLFEVDPQQYRIAADRARADLESMRRQI
EEEEEEEEHHHHHCCCEEEEEEECCCCCEECEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GASTAGIASAQAGLRAAQANEVKARQDSDRLERLYSEDPGTVSLRRLEVARATHTQAVSQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
VDAARAEVVRAREQQGGSEEDNAKLRSSAAALEKAELDLANSRVRARIAGLITDLRTEAG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QYAAAGSPVMTLIAIHDIWISADMTENNLGRVEPGTPVGIVLDALPGRVLSGRVRSIGYG
CCCCCCCCCEEHEEHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHCHHHHHCCC
VSVGQSPPPGSLPTVQNSRDWLRPAQRFPVIVEIDKGELTTLRGVRVGGQAEVMAFPTDG
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEEEECCCEEEEEECCCC
NPLNPLGRIFLHLMSWLSYVY
CCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDDAPPAPVSPPPAPAPSPTPSPSADPAGKGVKVVVVLIVLSLAWYLFADRYTPYTQQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHC
RVQAFVVPVASEVSGRVTRVLVHNNQDVQAGAVLFEVDPQQYRIAADRARADLESMRRQI
EEEEEEEEHHHHHCCCEEEEEEECCCCCEECEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GASTAGIASAQAGLRAAQANEVKARQDSDRLERLYSEDPGTVSLRRLEVARATHTQAVSQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
VDAARAEVVRAREQQGGSEEDNAKLRSSAAALEKAELDLANSRVRARIAGLITDLRTEAG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QYAAAGSPVMTLIAIHDIWISADMTENNLGRVEPGTPVGIVLDALPGRVLSGRVRSIGYG
CCCCCCCCCEEHEEHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHCHHHHHCCC
VSVGQSPPPGSLPTVQNSRDWLRPAQRFPVIVEIDKGELTTLRGVRVGGQAEVMAFPTDG
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEEEECCCEEEEEECCCC
NPLNPLGRIFLHLMSWLSYVY
CCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]