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The map label for this gene is cusC [H]

Identifier: 73541429

GI number: 73541429

Start: 1881118

End: 1882671

Strand: Reverse

Name: cusC [H]

Synonym: Reut_A1740

Alternate gene names: 73541429

Gene position: 1882671-1881118 (Counterclockwise)

Preceding gene: 73541430

Following gene: 73541428

Centisome position: 49.46

GC content: 66.67

Gene sequence:

>1554_bases
ATGCCGCTCCCGGCCCGTTCGCCCCTCCGGCTGATGATGGCGGCCTTGCTGCTCGGCGGCTGTACCCAGCTTGGCCCCGA
CTTCCAGGCGCAACGCGAGCCGTGGACCGAATCCTGGAGCAGCCCCTCACTCGAACAAGCCACTGAGCAACGGGAGCAGC
CCGACCTGCGCCAGTGGTGGCGGGTGTTCGACGACCCCATCCTGGAAAAACTGATTGCCGAGGCCGACGCCAATAACGCC
GGCGTCAGGATCGCGGGCCTGCGCGTGGTGGAGGCCCGGGCCCAGCTTGGCATTGCGCAGGCCGGGCGCTATCCGCAGGT
CCAGCAAGCGAGTGGCGAGGCGCTTTACGTCCATAGCCGGCAGTCCGGCGCCACGGTGCAGACCAGCCGCGTCTGGCAGT
TCAGCGCCGGTTTCGACGTTGGCTGGGAGCTGGATTTCTGGGGGCGCTTCAGCCGCGCGATCGAATCGGCGGATGCGGCA
TATTTTGCTTCCCAGGCCAACTATCAGGACGTACTGGTTCTGCTGCATGCGCAACTGGCCCAGACCTATTTCACTTTGCG
CACGGCCGAAGCACGGTTACGCATCGCACGCGAGAACGCGCGGCTGCAGAAGCGCAGCTATGAAATCACCGAACGCCTGT
TCAAGGGAGGCGAGAGCGACGAGCTCGATCTGCAGCAGGCCAAGACCCAATACCTCGGCACGCTGAGCAGCATTCCCGAA
CTGGAGGGCCAGATCCTGCATGCACGCAATGCGCTGGCCATCCTGATCGGGCGCCCGCCGGCTCCCATGCACGAACTGCT
GGACATGCCCGACAAGGAGGGTGTGGTGCCACTGATCGACCGGGCGGTGCTGCGGGACGTCCCGGCCAGCCTGCTGCTGC
GCCGCCCGGACATCCGCGCTGCCGAACTGCAGATGGCTGCGCAGTCGGCGCTGATCGGCGTGGCCAAGGCCGAGCTTTAT
CCGTCGCTGACGCTGCTCGGCAGCATTGGCTGGTCGGCCAGCTCGTTGCCCGCCACGCCTAACGGGCTGGTGCTGATCGC
CGGGCCCAGCCTGCGCTGGAATGTGTTCGACTACGGGCGCATCCGCAACAACGTGCGCATCCAGGATGCGCGCCTGCAGC
AGCTGATCGTTTCCTACCAGGACTCCGTGCGCCAGGCCGCGCGCGAGGCCGACGATGCCGCCAGCGGCCTGATCAAGGCG
CTGGAACGCGAAGCGATCCTGGCGCAGGCATCGCAGTCCGCGAACCGTTCGCTGGCGCTGGCCACTGCGCTGTTCCGCGA
GGGGTACTCGGACTTCCAGCGCGTGCTGGACGCCCAGCGCGCGCTGTTTGCCCAGCAGGACGCTTACCTGGTCAACCGCA
GCACGGCAGTCGCGGATCTGATCGCACTGTACAAGGCGCTCGGCGGTGGCTGGGACACGGCGCAGCCGCTCGTCGATACC
GCGACACGGCAGCAGATGGAGCAACGTACCGACTGGGGCGGCCTGCTCGACGAGACGGTGAACGCTACAACCGGCAAACG
CTCTTCCTTGCAGCGAGGCACACCCAATGAGTGA

Upstream 100 bases:

>100_bases
TATGCCGCAGGTTCCCACCATGGGAATGACGATCCGCCTAAGGCTACCCGGCATGCGCGCCCGGCGCTGGCCTGTTCTTT
GCCGTGGCCGGTAGCTGACC

Downstream 100 bases:

>100_bases
CGACGCGCCACCCGCCCCGGTATCTCCGCCCCCGGCGCCCGCGCCATCGCCAACGCCATCTCCCTCGGCAGATCCGGCCG
GAAAGGGCGTAAAGGTGGTG

Product: RND efflux system, outer membrane lipoprotein, NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MPLPARSPLRLMMAALLLGGCTQLGPDFQAQREPWTESWSSPSLEQATEQREQPDLRQWWRVFDDPILEKLIAEADANNA
GVRIAGLRVVEARAQLGIAQAGRYPQVQQASGEALYVHSRQSGATVQTSRVWQFSAGFDVGWELDFWGRFSRAIESADAA
YFASQANYQDVLVLLHAQLAQTYFTLRTAEARLRIARENARLQKRSYEITERLFKGGESDELDLQQAKTQYLGTLSSIPE
LEGQILHARNALAILIGRPPAPMHELLDMPDKEGVVPLIDRAVLRDVPASLLLRRPDIRAAELQMAAQSALIGVAKAELY
PSLTLLGSIGWSASSLPATPNGLVLIAGPSLRWNVFDYGRIRNNVRIQDARLQQLIVSYQDSVRQAAREADDAASGLIKA
LEREAILAQASQSANRSLALATALFREGYSDFQRVLDAQRALFAQQDAYLVNRSTAVADLIALYKALGGGWDTAQPLVDT
ATRQQMEQRTDWGGLLDETVNATTGKRSSLQRGTPNE

Sequences:

>Translated_517_residues
MPLPARSPLRLMMAALLLGGCTQLGPDFQAQREPWTESWSSPSLEQATEQREQPDLRQWWRVFDDPILEKLIAEADANNA
GVRIAGLRVVEARAQLGIAQAGRYPQVQQASGEALYVHSRQSGATVQTSRVWQFSAGFDVGWELDFWGRFSRAIESADAA
YFASQANYQDVLVLLHAQLAQTYFTLRTAEARLRIARENARLQKRSYEITERLFKGGESDELDLQQAKTQYLGTLSSIPE
LEGQILHARNALAILIGRPPAPMHELLDMPDKEGVVPLIDRAVLRDVPASLLLRRPDIRAAELQMAAQSALIGVAKAELY
PSLTLLGSIGWSASSLPATPNGLVLIAGPSLRWNVFDYGRIRNNVRIQDARLQQLIVSYQDSVRQAAREADDAASGLIKA
LEREAILAQASQSANRSLALATALFREGYSDFQRVLDAQRALFAQQDAYLVNRSTAVADLIALYKALGGGWDTAQPLVDT
ATRQQMEQRTDWGGLLDETVNATTGKRSSLQRGTPNE
>Mature_516_residues
PLPARSPLRLMMAALLLGGCTQLGPDFQAQREPWTESWSSPSLEQATEQREQPDLRQWWRVFDDPILEKLIAEADANNAG
VRIAGLRVVEARAQLGIAQAGRYPQVQQASGEALYVHSRQSGATVQTSRVWQFSAGFDVGWELDFWGRFSRAIESADAAY
FASQANYQDVLVLLHAQLAQTYFTLRTAEARLRIARENARLQKRSYEITERLFKGGESDELDLQQAKTQYLGTLSSIPEL
EGQILHARNALAILIGRPPAPMHELLDMPDKEGVVPLIDRAVLRDVPASLLLRRPDIRAAELQMAAQSALIGVAKAELYP
SLTLLGSIGWSASSLPATPNGLVLIAGPSLRWNVFDYGRIRNNVRIQDARLQQLIVSYQDSVRQAAREADDAASGLIKAL
EREAILAQASQSANRSLALATALFREGYSDFQRVLDAQRALFAQQDAYLVNRSTAVADLIALYKALGGGWDTAQPLVDTA
TRQQMEQRTDWGGLLDETVNATTGKRSSLQRGTPNE

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=484, Percent_Identity=33.2644628099174, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI2367348, Length=442, Percent_Identity=25.7918552036199, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 57072; Mature: 56941

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPARSPLRLMMAALLLGGCTQLGPDFQAQREPWTESWSSPSLEQATEQREQPDLRQWW
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
RVFDDPILEKLIAEADANNAGVRIAGLRVVEARAQLGIAQAGRYPQVQQASGEALYVHSR
HHHCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC
QSGATVQTSRVWQFSAGFDVGWELDFWGRFSRAIESADAAYFASQANYQDVLVLLHAQLA
CCCCEEEECEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QTYFTLRTAEARLRIARENARLQKRSYEITERLFKGGESDELDLQQAKTQYLGTLSSIPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCH
LEGQILHARNALAILIGRPPAPMHELLDMPDKEGVVPLIDRAVLRDVPASLLLRRPDIRA
HCCHHEECCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCH
AELQMAAQSALIGVAKAELYPSLTLLGSIGWSASSLPATPNGLVLIAGPSLRWNVFDYGR
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEECEEHHH
IRNNVRIQDARLQQLIVSYQDSVRQAAREADDAASGLIKALEREAILAQASQSANRSLAL
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ATALFREGYSDFQRVLDAQRALFAQQDAYLVNRSTAVADLIALYKALGGGWDTAQPLVDT
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHH
ATRQQMEQRTDWGGLLDETVNATTGKRSSLQRGTPNE
HHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PLPARSPLRLMMAALLLGGCTQLGPDFQAQREPWTESWSSPSLEQATEQREQPDLRQWW
CCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
RVFDDPILEKLIAEADANNAGVRIAGLRVVEARAQLGIAQAGRYPQVQQASGEALYVHSR
HHHCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC
QSGATVQTSRVWQFSAGFDVGWELDFWGRFSRAIESADAAYFASQANYQDVLVLLHAQLA
CCCCEEEECEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QTYFTLRTAEARLRIARENARLQKRSYEITERLFKGGESDELDLQQAKTQYLGTLSSIPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCH
LEGQILHARNALAILIGRPPAPMHELLDMPDKEGVVPLIDRAVLRDVPASLLLRRPDIRA
HCCHHEECCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCH
AELQMAAQSALIGVAKAELYPSLTLLGSIGWSASSLPATPNGLVLIAGPSLRWNVFDYGR
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEECEEHHH
IRNNVRIQDARLQQLIVSYQDSVRQAAREADDAASGLIKALEREAILAQASQSANRSLAL
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ATALFREGYSDFQRVLDAQRALFAQQDAYLVNRSTAVADLIALYKALGGGWDTAQPLVDT
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCCCCHHHHHHH
ATRQQMEQRTDWGGLLDETVNATTGKRSSLQRGTPNE
HHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]