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The map label for this gene is glnP [H]

Identifier: 73541283

GI number: 73541283

Start: 1715275

End: 1715943

Strand: Reverse

Name: glnP [H]

Synonym: Reut_A1593

Alternate gene names: 73541283

Gene position: 1715943-1715275 (Counterclockwise)

Preceding gene: 73541284

Following gene: 73541282

Centisome position: 45.08

GC content: 61.73

Gene sequence:

>669_bases
ATGGAACTGGATTTTTCTCCCGTCTTCAGCGGCTGGCCTGACATCGTCCACGGTGCCATCGTCACCGTGGAAGTGACAGC
CTGCGCGCTGGTATTGGGCTGCGTCATGGGCCTGCTGGTCGGTATCGGCCGGCTCGACCCGAAGCGTCGCGTCATCTACA
GCATCTGTACGGCCTATGTGACGTTCATCCGCGGCACGCCGCTGCTGGTACAGCTGTTCCTGCTGTTCTTCGGGCTGCCG
CAATTCAACATCATGCTGCCGGCCTTTGTCTGCGGCGTGATCGGGCTGGGCGTCTATTCCGGCGCCTATGTATCGGAAAT
CGTGCGAGGCGCAATCCAGTCGGTGGAAAAAGGCCAGATGGAAGCGGCCCGCTCGATCGGCATGTCTTCGGGCCAGGCCA
TGCGCGCGGTGATCCTGCCGCAGGCCATCGTGCGGATGATTCCGCCGCTGGGTAACGAGTTCATCGCGCTGATCAAGAAC
TCGGCACTGGTCTCGCTGCTGACCATTGCCGACCTGATGCACGAGGGCCAGAAGATCATCAGCGTGTCGTACCGGTCGCT
GGAAGTCTATCTGGCGATCGCGCTGGTTTATCTGATCCTGACGAGCGCGGCCGGGCTGATCCTGCGGCGCGCAGAACAAC
GCCTGCGCATGGGAGGCATGGTGCAATGA

Upstream 100 bases:

>100_bases
TGCGGCGCTCGTCAAAGTGAAGGCCGATGGCACCTACGCCAAGCTGACCCAGAAGTGGTTCGGCACGGCCGCCTCCAAGT
AACCCGAGCCGGTCATCATC

Downstream 100 bases:

>100_bases
GCGATTCCGCAATCATCCGGATCCGGAACCTGGGCAAATCTTTCGGCGGCCATACCGTCCTGCGCGGCATCGACTTCGAT
GTCGAGCCGTCGCAGGTCGT

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MELDFSPVFSGWPDIVHGAIVTVEVTACALVLGCVMGLLVGIGRLDPKRRVIYSICTAYVTFIRGTPLLVQLFLLFFGLP
QFNIMLPAFVCGVIGLGVYSGAYVSEIVRGAIQSVEKGQMEAARSIGMSSGQAMRAVILPQAIVRMIPPLGNEFIALIKN
SALVSLLTIADLMHEGQKIISVSYRSLEVYLAIALVYLILTSAAGLILRRAEQRLRMGGMVQ

Sequences:

>Translated_222_residues
MELDFSPVFSGWPDIVHGAIVTVEVTACALVLGCVMGLLVGIGRLDPKRRVIYSICTAYVTFIRGTPLLVQLFLLFFGLP
QFNIMLPAFVCGVIGLGVYSGAYVSEIVRGAIQSVEKGQMEAARSIGMSSGQAMRAVILPQAIVRMIPPLGNEFIALIKN
SALVSLLTIADLMHEGQKIISVSYRSLEVYLAIALVYLILTSAAGLILRRAEQRLRMGGMVQ
>Mature_222_residues
MELDFSPVFSGWPDIVHGAIVTVEVTACALVLGCVMGLLVGIGRLDPKRRVIYSICTAYVTFIRGTPLLVQLFLLFFGLP
QFNIMLPAFVCGVIGLGVYSGAYVSEIVRGAIQSVEKGQMEAARSIGMSSGQAMRAVILPQAIVRMIPPLGNEFIALIKN
SALVSLLTIADLMHEGQKIISVSYRSLEVYLAIALVYLILTSAAGLILRRAEQRLRMGGMVQ

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=219, Percent_Identity=37.8995433789954, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788226, Length=204, Percent_Identity=36.7647058823529, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786874, Length=230, Percent_Identity=30.8695652173913, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1788646, Length=215, Percent_Identity=32.5581395348837, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786873, Length=221, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788645, Length=207, Percent_Identity=32.3671497584541, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=28.125, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787086, Length=217, Percent_Identity=26.7281105990783, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=30.622009569378, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994930, Length=196, Percent_Identity=32.1428571428571, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23989; Mature: 23989

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELDFSPVFSGWPDIVHGAIVTVEVTACALVLGCVMGLLVGIGRLDPKRRVIYSICTAYV
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TFIRGTPLLVQLFLLFFGLPQFNIMLPAFVCGVIGLGVYSGAYVSEIVRGAIQSVEKGQM
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
EAARSIGMSSGQAMRAVILPQAIVRMIPPLGNEFIALIKNSALVSLLTIADLMHEGQKII
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SVSYRSLEVYLAIALVYLILTSAAGLILRRAEQRLRMGGMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELDFSPVFSGWPDIVHGAIVTVEVTACALVLGCVMGLLVGIGRLDPKRRVIYSICTAYV
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TFIRGTPLLVQLFLLFFGLPQFNIMLPAFVCGVIGLGVYSGAYVSEIVRGAIQSVEKGQM
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
EAARSIGMSSGQAMRAVILPQAIVRMIPPLGNEFIALIKNSALVSLLTIADLMHEGQKII
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SVSYRSLEVYLAIALVYLILTSAAGLILRRAEQRLRMGGMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]