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The map label for this gene is mocR [H]

Identifier: 73541270

GI number: 73541270

Start: 1702064

End: 1703581

Strand: Direct

Name: mocR [H]

Synonym: Reut_A1580

Alternate gene names: 73541270

Gene position: 1702064-1703581 (Clockwise)

Preceding gene: 73541266

Following gene: 73541274

Centisome position: 44.71

GC content: 66.27

Gene sequence:

>1518_bases
ATGACTGCACGGACCTCCGCATTGGCCATCGAAATCGACCGCCAGGACCGCTCGCCGATCTATCTGCAGATTTGCGAGCG
CTTCAGGACGGCCATCGCAGCAGGGCACCTGCGTCCCGGTGATCGCGTGCCCGCGCTTCGGGGGCTTGCCTTGCAGCTGA
ATACGGCACGCGGCACGGTTGAAATGGCCTATACCATCCTGGTCGACGAGGGCTACCTGCAGATGCGCGGTGCGGCGGGG
ACGTTCGTCTCAGCGTCGTTGCCGGCATCGGTGACGCGCCCGGCACGTGGCGGGGATCGGGAGCAGCCGCCCGCCAGGGA
GCAGGGCGCGACGAAATCGTCCCATGCGTTGCGCGGTCGTCAGCCGGCAACGCGTCAACTGGCGATCGCCGTGGCGATGA
GCGGGGAGCCGAAGCTCTTGCAACCCGGGCTGCCGGCGCTGGACGCGTTCCCGCGCAAGCTGTGGAACCGGCTCGTCTCG
CGTTGCGCGCGCAGCGGTGAGCGCGCGATGCTGGCCTATCCGGATCCGGTTGGTTACCGCGCGCTGCGCGAGCACATTGC
CACCTATCTGGGCTTGTCGCGGGGCGTGGCGTGCGTGCCGGAGCAGGTATTCATCACCGCTGGCTACCGCGCGACGCTCG
AACTTGTCTTGCGCAGTCTCGCGAGTCCCAATGACCGCATGTGGTTCGAAGACCCCGGCTACCTGCTCGCACGCGGCTTT
CTGGCCGAAGTCGGCGTCAATCTCGTACCGGTGCCGATCGACAGCGAAGGGATCGATGTCGACCGCGGCATCGCGCTGGA
TCCGCTCGCGCGTTTCGCACTGGTGACGCCATCGCACCAGGCGCCGCTCGGATACACATTGTCGCTCGCCAGGCGCATGG
CGCTCCTCGACTGGGCGGCGAAAGGGTCAAGCTGGATCATTGAAGACGACTACGACAGCGAATTCCGCTATGTGGGCCGG
CCACTGCCGGCATTGAAAAGCCTCGACAAGGACGATCGCGTGATCTATTGCGGCACGTTCAGCAAGGTGATGTTTCCGGG
ACTACGGCTCGCGTATGCCGTGGTGCCGGAGCGTGCGGTCGAACGCGTGGAGCGCGTGGCCTGCAGCATGAATGCCGGCT
CGCCGACGCTATTGCAGGCGGCCGTGGCGGACTTCATCGAACAGGGACATTTTGCGCGCCACGTAAAGCGGATGCGTGCG
TTGTACGGGCAGCGCCGCACGCTGATTGCGCATGCGCTGGAGCAGGCGTTCGGCGAGCGCATGCTTGTGGAGCTGCCGCA
CGGCGGCATCCAGTTCGCGGTCCAGTTTGCCGAAGGTCCCGATGGTCCCGTCGACGACGTGGCCGTTGCCGCGCGCGCAC
GCGACGCGGGGCTCGCGGTGGTGCCACTGTCGATCTGGTATGCGAACGGACGCACGCGGCGCACCCCGCGTGGCCTGGTC
ATGGGCTTCGCCAACGTAACCGATGCGAGAGAGGCATTGCGTCTCGCGCGAACGCTATACGGTTGCCTGACCGGTTAA

Upstream 100 bases:

>100_bases
TGAGACCATTGTGGAACAATCATGCCCTATGGATAAGGGCCAAGAATTGTCGAAATGACTAGGCCAAGTCCAGCCTGTTC
ACATTGCCCGCGAACCCATC

Downstream 100 bases:

>100_bases
GCCCGCACGAAACTGGACAAGTCCGTCAATCTGCCCGGCGCCATGAGGCCCCAGCTTGCTCACAGGGCAAACACGATTGT
CACCAGCAGCGAAATCCACA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTARTSALAIEIDRQDRSPIYLQICERFRTAIAAGHLRPGDRVPALRGLALQLNTARGTVEMAYTILVDEGYLQMRGAAG
TFVSASLPASVTRPARGGDREQPPAREQGATKSSHALRGRQPATRQLAIAVAMSGEPKLLQPGLPALDAFPRKLWNRLVS
RCARSGERAMLAYPDPVGYRALREHIATYLGLSRGVACVPEQVFITAGYRATLELVLRSLASPNDRMWFEDPGYLLARGF
LAEVGVNLVPVPIDSEGIDVDRGIALDPLARFALVTPSHQAPLGYTLSLARRMALLDWAAKGSSWIIEDDYDSEFRYVGR
PLPALKSLDKDDRVIYCGTFSKVMFPGLRLAYAVVPERAVERVERVACSMNAGSPTLLQAAVADFIEQGHFARHVKRMRA
LYGQRRTLIAHALEQAFGERMLVELPHGGIQFAVQFAEGPDGPVDDVAVAARARDAGLAVVPLSIWYANGRTRRTPRGLV
MGFANVTDAREALRLARTLYGCLTG

Sequences:

>Translated_505_residues
MTARTSALAIEIDRQDRSPIYLQICERFRTAIAAGHLRPGDRVPALRGLALQLNTARGTVEMAYTILVDEGYLQMRGAAG
TFVSASLPASVTRPARGGDREQPPAREQGATKSSHALRGRQPATRQLAIAVAMSGEPKLLQPGLPALDAFPRKLWNRLVS
RCARSGERAMLAYPDPVGYRALREHIATYLGLSRGVACVPEQVFITAGYRATLELVLRSLASPNDRMWFEDPGYLLARGF
LAEVGVNLVPVPIDSEGIDVDRGIALDPLARFALVTPSHQAPLGYTLSLARRMALLDWAAKGSSWIIEDDYDSEFRYVGR
PLPALKSLDKDDRVIYCGTFSKVMFPGLRLAYAVVPERAVERVERVACSMNAGSPTLLQAAVADFIEQGHFARHVKRMRA
LYGQRRTLIAHALEQAFGERMLVELPHGGIQFAVQFAEGPDGPVDDVAVAARARDAGLAVVPLSIWYANGRTRRTPRGLV
MGFANVTDAREALRLARTLYGCLTG
>Mature_504_residues
TARTSALAIEIDRQDRSPIYLQICERFRTAIAAGHLRPGDRVPALRGLALQLNTARGTVEMAYTILVDEGYLQMRGAAGT
FVSASLPASVTRPARGGDREQPPAREQGATKSSHALRGRQPATRQLAIAVAMSGEPKLLQPGLPALDAFPRKLWNRLVSR
CARSGERAMLAYPDPVGYRALREHIATYLGLSRGVACVPEQVFITAGYRATLELVLRSLASPNDRMWFEDPGYLLARGFL
AEVGVNLVPVPIDSEGIDVDRGIALDPLARFALVTPSHQAPLGYTLSLARRMALLDWAAKGSSWIIEDDYDSEFRYVGRP
LPALKSLDKDDRVIYCGTFSKVMFPGLRLAYAVVPERAVERVERVACSMNAGSPTLLQAAVADFIEQGHFARHVKRMRAL
YGQRRTLIAHALEQAFGERMLVELPHGGIQFAVQFAEGPDGPVDDVAVAARARDAGLAVVPLSIWYANGRTRRTPRGLVM
GFANVTDAREALRLARTLYGCLTG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=285, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33469970, Length=285, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790797, Length=451, Percent_Identity=28.159645232816, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787710, Length=399, Percent_Identity=28.3208020050125, Blast_Score=135, Evalue=8e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55181; Mature: 55050

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTSALAIEIDRQDRSPIYLQICERFRTAIAAGHLRPGDRVPALRGLALQLNTARGTV
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEEEECCCCEE
EMAYTILVDEGYLQMRGAAGTFVSASLPASVTRPARGGDREQPPAREQGATKSSHALRGR
EEEEEEEEECCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCCC
QPATRQLAIAVAMSGEPKLLQPGLPALDAFPRKLWNRLVSRCARSGERAMLAYPDPVGYR
CCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
ALREHIATYLGLSRGVACVPEQVFITAGYRATLELVLRSLASPNDRMWFEDPGYLLARGF
HHHHHHHHHHHHHCCCEECCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHH
LAEVGVNLVPVPIDSEGIDVDRGIALDPLARFALVTPSHQAPLGYTLSLARRMALLDWAA
HHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHC
KGSSWIIEDDYDSEFRYVGRPLPALKSLDKDDRVIYCGTFSKVMFPGLRLAYAVVPERAV
CCCCEEEECCCCCCHHHCCCCCHHHHCCCCCCCEEEEECHHHHHCCCHHHHHHHHHHHHH
ERVERVACSMNAGSPTLLQAAVADFIEQGHFARHVKRMRALYGQRRTLIAHALEQAFGER
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
MLVELPHGGIQFAVQFAEGPDGPVDDVAVAARARDAGLAVVPLSIWYANGRTRRTPRGLV
EEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCE
MGFANVTDAREALRLARTLYGCLTG
EECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARTSALAIEIDRQDRSPIYLQICERFRTAIAAGHLRPGDRVPALRGLALQLNTARGTV
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEEEECCCCEE
EMAYTILVDEGYLQMRGAAGTFVSASLPASVTRPARGGDREQPPAREQGATKSSHALRGR
EEEEEEEEECCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHCCC
QPATRQLAIAVAMSGEPKLLQPGLPALDAFPRKLWNRLVSRCARSGERAMLAYPDPVGYR
CCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
ALREHIATYLGLSRGVACVPEQVFITAGYRATLELVLRSLASPNDRMWFEDPGYLLARGF
HHHHHHHHHHHHHCCCEECCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHH
LAEVGVNLVPVPIDSEGIDVDRGIALDPLARFALVTPSHQAPLGYTLSLARRMALLDWAA
HHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHC
KGSSWIIEDDYDSEFRYVGRPLPALKSLDKDDRVIYCGTFSKVMFPGLRLAYAVVPERAV
CCCCEEEECCCCCCHHHCCCCCHHHHCCCCCCCEEEEECHHHHHCCCHHHHHHHHHHHHH
ERVERVACSMNAGSPTLLQAAVADFIEQGHFARHVKRMRALYGQRRTLIAHALEQAFGER
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
MLVELPHGGIQFAVQFAEGPDGPVDDVAVAARARDAGLAVVPLSIWYANGRTRRTPRGLV
EEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCE
MGFANVTDAREALRLARTLYGCLTG
EECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]