| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is fabG [H]
Identifier: 73541267
GI number: 73541267
Start: 1699739
End: 1700536
Strand: Reverse
Name: fabG [H]
Synonym: Reut_A1577
Alternate gene names: 73541267
Gene position: 1700536-1699739 (Counterclockwise)
Preceding gene: 73541268
Following gene: 73541244
Centisome position: 44.67
GC content: 66.54
Gene sequence:
>798_bases GTGACGACCCAACATCCTGCCGCCAGCGAGTTTCGCGTGGCCCTGAATAGCCCGGCCAGCAGTGTCGTGATTACCGGCGG CGCCTCCGGCATTGGCGAGGCTTGCGCGGAGGCCCTGGCCGCTGTCGGGCGGCCTGTAGCGATCTGGGATATCCAGGAGG ACAAGGCGCGAGCCGTCGCGGCGACGCTGGCCGAACGCTATGACGTACCCGCTTTCGGGCTCGGCATTGACCTGCGGGTA CCCGCAGGGCTCGAAGATGCGCTGGCCCGCACCCGCGCCGCCCTGCCGGCGCTCGGCGGCATGGTGCATGCCGCCGGCGT GGTGGACCAGAGCGGTATCGAGGGCCTGACGCAGGCTCGCTGGGATGCCGTGCTCGATGTCAATCTGCGCGCTATGCCGC TGCTGGTGCAGGCCATGCTGGCCGACTTGCGCCAGCAACCGGGCGCCGCCGTTGTCGCCATCGCATCGATCAATGCGACA TTGGGCAATGGATTGATTCCGGCTTATTCGGCTTCCAAGGGCGGCTTGCTCTCACTGGTGCGTTCCCTTGCCGACAGCCT GGGCCAGGACGGGATCCGCATCAATGCCGTCTCTCCGGGACAGATCCACACGCCGATGCTCCAGCCTGCCATCGACGCCC TGCCGCCTGGCACCTTTGAGCGCCGCATCCAGTTGGGCCGCCTTGGCACGCCCGCAGAGATCGGACGCGTAGTCCGTTTC CTGCTGTCTGACGAAGCCAGCTATGTCACCGGCACCGAACTGGTTGTCGACGGCGGCAATATTCCTTCGCAACGCTAA
Upstream 100 bases:
>100_bases TTTGGACTATGTCACCTTGGACGTGAGCAGAAACAATGCGTATGGCAGCCGCGCCTGTTTCGGCTGTGACGCTAACCAAG ACATCCGGGAGAGACAACAA
Downstream 100 bases:
>100_bases GCGGAAAAAGGCGAAATGCGCCTTCGCGCATTTCGTCTCCCTCCTGGCCACCAGCTTCAGGCCTCAAGCCTCGAACACGT GCCCCAGCGTTGGCGGTTCG
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 265; Mature: 264
Protein sequence:
>265_residues MTTQHPAASEFRVALNSPASSVVITGGASGIGEACAEALAAVGRPVAIWDIQEDKARAVAATLAERYDVPAFGLGIDLRV PAGLEDALARTRAALPALGGMVHAAGVVDQSGIEGLTQARWDAVLDVNLRAMPLLVQAMLADLRQQPGAAVVAIASINAT LGNGLIPAYSASKGGLLSLVRSLADSLGQDGIRINAVSPGQIHTPMLQPAIDALPPGTFERRIQLGRLGTPAEIGRVVRF LLSDEASYVTGTELVVDGGNIPSQR
Sequences:
>Translated_265_residues MTTQHPAASEFRVALNSPASSVVITGGASGIGEACAEALAAVGRPVAIWDIQEDKARAVAATLAERYDVPAFGLGIDLRV PAGLEDALARTRAALPALGGMVHAAGVVDQSGIEGLTQARWDAVLDVNLRAMPLLVQAMLADLRQQPGAAVVAIASINAT LGNGLIPAYSASKGGLLSLVRSLADSLGQDGIRINAVSPGQIHTPMLQPAIDALPPGTFERRIQLGRLGTPAEIGRVVRF LLSDEASYVTGTELVVDGGNIPSQR >Mature_264_residues TTQHPAASEFRVALNSPASSVVITGGASGIGEACAEALAAVGRPVAIWDIQEDKARAVAATLAERYDVPAFGLGIDLRVP AGLEDALARTRAALPALGGMVHAAGVVDQSGIEGLTQARWDAVLDVNLRAMPLLVQAMLADLRQQPGAAVVAIASINATL GNGLIPAYSASKGGLLSLVRSLADSLGQDGIRINAVSPGQIHTPMLQPAIDALPPGTFERRIQLGRLGTPAEIGRVVRFL LSDEASYVTGTELVVDGGNIPSQR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=34.0336134453782, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=29.5652173913043, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI32483357, Length=153, Percent_Identity=34.640522875817, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI4503301, Length=232, Percent_Identity=29.3103448275862, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=34.2857142857143, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI126723750, Length=145, Percent_Identity=33.7931034482759, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI59889578, Length=156, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI33667109, Length=228, Percent_Identity=32.4561403508772, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=32.2448979591837, Blast_Score=121, Evalue=6e-29, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=28.1124497991968, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=31.3725490196078, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789208, Length=240, Percent_Identity=28.75, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=26.5560165975104, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=27.9835390946502, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.0204081632653, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=33.0677290836653, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.5220883534137, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=27.0491803278689, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=33.7349397590361, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=32.9268292682927, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=30.4166666666667, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=29.5719844357977, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=29.2490118577075, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=29.5719844357977, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=245, Percent_Identity=25.3061224489796, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=28.8537549407115, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=28.125, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17536025, Length=277, Percent_Identity=27.0758122743682, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=25.8687258687259, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=26.5625, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=9e-14, Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=32.3651452282158, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=31.2757201646091, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=31.8367346938775, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=28.3950617283951, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.0756972111554, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=243, Percent_Identity=27.5720164609054, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=33.0769230769231, Blast_Score=80, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27261; Mature: 27129
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTQHPAASEFRVALNSPASSVVITGGASGIGEACAEALAAVGRPVAIWDIQEDKARAVA CCCCCCCCCHHEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHH ATLAERYDVPAFGLGIDLRVPAGLEDALARTRAALPALGGMVHAAGVVDQSGIEGLTQAR HHHHHHCCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH WDAVLDVNLRAMPLLVQAMLADLRQQPGAAVVAIASINATLGNGLIPAYSASKGGLLSLV HHHEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHCCCCCCCCCCCCCCHHHHH RSLADSLGQDGIRINAVSPGQIHTPMLQPAIDALPPGTFERRIQLGRLGTPAEIGRVVRF HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHH LLSDEASYVTGTELVVDGGNIPSQR HHCCCCCEEECCEEEEECCCCCCCC >Mature Secondary Structure TTQHPAASEFRVALNSPASSVVITGGASGIGEACAEALAAVGRPVAIWDIQEDKARAVA CCCCCCCCHHEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHH ATLAERYDVPAFGLGIDLRVPAGLEDALARTRAALPALGGMVHAAGVVDQSGIEGLTQAR HHHHHHCCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH WDAVLDVNLRAMPLLVQAMLADLRQQPGAAVVAIASINATLGNGLIPAYSASKGGLLSLV HHHEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHCCCCCCCCCCCCCCHHHHH RSLADSLGQDGIRINAVSPGQIHTPMLQPAIDALPPGTFERRIQLGRLGTPAEIGRVVRF HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHH LLSDEASYVTGTELVVDGGNIPSQR HHCCCCCEEECCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]