| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is fabG [C]
Identifier: 73541244
GI number: 73541244
Start: 1674026
End: 1674856
Strand: Reverse
Name: fabG [C]
Synonym: Reut_A1554
Alternate gene names: 73541244
Gene position: 1674856-1674026 (Counterclockwise)
Preceding gene: 73541267
Following gene: 73541243
Centisome position: 44.0
GC content: 67.39
Gene sequence:
>831_bases ATGGATTTCCAAGGCAAGACTGTATTGATCACCGGCGGCGGCGCCGGCATCGGGCTGGCGGCCGCACAGGCCTTTCAGGA ACAGGGCGCCCGCGTGGCGGTGATCGAGATCGATCCGAGCCGCGCCGACGCCGCCGTATCCTTGCTCGGCGGCGATGGCA ACGACGCACTGGTCGTGCACGGCGACGTCACCTGCGCTGCGACCGTGGCTTCACTCGCCGCGCAGATCGGCGAACGCTTC GGCGCGCTCGATGTGCTGGTCAATAACGTCGGTGACTTCCTGCGCATCGCCAAGCCCTTCGAACTGTATGACGACGCCGA GATCGACAGCCTGTACGCGGTCAACCTGCGCCATGTCTTCTCGGTCACACGCGCGATGCTGCCTCTGCTCCGGCGCAGCG CGGCGGCGAGCATCGTCAGCGTGTCGTCGATCGAGGGCTTCCGCGGCATCCCGAACTGCAGCGTCTATGGCGCGTTCAAG GCCGCACTGACCGGCTTCACGCAGAGCCTTGCGCTCGAGCTGGCGCCGTCGGGCATCCGCGTCAACCTGATCGCACCCGA GACCACGGAAACGCCGCAGGTGCCGGTGTCGCTGGTCGTTGCGGAAGAGCACCGGCACCACATGCCGAACTGGATCCCGC TGGGCCGGTTCGGCACGCCGCGGGACATTGCCGAAGGCATCGTGTTCCTGGCGGGCCCGCGCGCCTCGTGGATCACGGGC ACGGCCCTGCATGTGAACGGCGGCGCGCTGGCGGCGTCCGGCTGGTACCGCGACCCGAAAGGCAACTGGACCAATATGCC GGTGATGGTCGGCAACGGCATGAACCTCTGA
Upstream 100 bases:
>100_bases CGCCACCACGGCGCTTCAAAGTCGCCACGGGCGGCCTGCTACGGTCGCTGTCGACCTTTCCCTGCATCTACCGCCACGAC GAAGAAGGAGACTGAGACTG
Downstream 100 bases:
>100_bases CGGCTGATCGAACCCGTCGTAAGCATCAGCCACCCAACAACAACCACGAGCAAGGAGAACAGCATGAAGATTCTGATCGT CGGCGGCACGGGCATGATTG
Product: Short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 276; Mature: 276
Protein sequence:
>276_residues MDFQGKTVLITGGGAGIGLAAAQAFQEQGARVAVIEIDPSRADAAVSLLGGDGNDALVVHGDVTCAATVASLAAQIGERF GALDVLVNNVGDFLRIAKPFELYDDAEIDSLYAVNLRHVFSVTRAMLPLLRRSAAASIVSVSSIEGFRGIPNCSVYGAFK AALTGFTQSLALELAPSGIRVNLIAPETTETPQVPVSLVVAEEHRHHMPNWIPLGRFGTPRDIAEGIVFLAGPRASWITG TALHVNGGALAASGWYRDPKGNWTNMPVMVGNGMNL
Sequences:
>Translated_276_residues MDFQGKTVLITGGGAGIGLAAAQAFQEQGARVAVIEIDPSRADAAVSLLGGDGNDALVVHGDVTCAATVASLAAQIGERF GALDVLVNNVGDFLRIAKPFELYDDAEIDSLYAVNLRHVFSVTRAMLPLLRRSAAASIVSVSSIEGFRGIPNCSVYGAFK AALTGFTQSLALELAPSGIRVNLIAPETTETPQVPVSLVVAEEHRHHMPNWIPLGRFGTPRDIAEGIVFLAGPRASWITG TALHVNGGALAASGWYRDPKGNWTNMPVMVGNGMNL >Mature_276_residues MDFQGKTVLITGGGAGIGLAAAQAFQEQGARVAVIEIDPSRADAAVSLLGGDGNDALVVHGDVTCAATVASLAAQIGERF GALDVLVNNVGDFLRIAKPFELYDDAEIDSLYAVNLRHVFSVTRAMLPLLRRSAAASIVSVSSIEGFRGIPNCSVYGAFK AALTGFTQSLALELAPSGIRVNLIAPETTETPQVPVSLVVAEEHRHHMPNWIPLGRFGTPRDIAEGIVFLAGPRASWITG TALHVNGGALAASGWYRDPKGNWTNMPVMVGNGMNL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=33.1983805668016, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=32.6693227091633, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=33.739837398374, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=34.1463414634146, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=34.1772151898734, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=30.3703703703704, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=30.241935483871, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=30.4, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI19923817, Length=279, Percent_Identity=27.5985663082437, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=195, Percent_Identity=34.8717948717949, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=30, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=33.6842105263158, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI31542939, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4758504, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=31.8918918918919, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI20149619, Length=237, Percent_Identity=27.0042194092827, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=206, Percent_Identity=26.6990291262136, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=34.2741935483871, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=34.3629343629344, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=30.6451612903226, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=34.4961240310078, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=6e-25, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.8537549407115, Blast_Score=101, Evalue=7e-23, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=27.6679841897233, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=31.0756972111554, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=28.8537549407115, Blast_Score=81, Evalue=9e-17, Organism=Escherichia coli, GI1788891, Length=189, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787545, Length=261, Percent_Identity=25.2873563218391, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=27.2222222222222, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=32.1285140562249, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.7619047619048, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=32.046332046332, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=35.1778656126482, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=34, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=31.5985130111524, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=32.183908045977, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=32.183908045977, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=32.3308270676692, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=30.2583025830258, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=30.0380228136882, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=29.1187739463602, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=30.7407407407407, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=30.1470588235294, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=29.1512915129151, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=30.0380228136882, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=29.5620437956204, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=30, Blast_Score=90, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562908, Length=282, Percent_Identity=31.5602836879433, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=32.9501915708812, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17567345, Length=228, Percent_Identity=27.6315789473684, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.4436090225564, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17568967, Length=286, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538182, Length=234, Percent_Identity=29.0598290598291, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=27.5092936802974, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=28.4974093264249, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=28.6290322580645, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=28.8770053475936, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=2e-24, Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=29.1338582677165, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=201, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=36.6533864541833, Blast_Score=126, Evalue=2e-29, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=34.8, Blast_Score=118, Evalue=5e-27, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=32.6693227091633, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24643142, Length=259, Percent_Identity=32.4324324324324, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=35.3174603174603, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=29.2307692307692, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=34.1836734693878, Blast_Score=88, Evalue=8e-18, Organism=Drosophila melanogaster, GI24640492, Length=234, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24665243, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI221331218, Length=196, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI281364892, Length=198, Percent_Identity=32.3232323232323, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=30.1020408163265, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI17737361, Length=228, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24665247, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI221331216, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 28929; Mature: 28929
Theoretical pI: Translated: 5.58; Mature: 5.58
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDFQGKTVLITGGGAGIGLAAAQAFQEQGARVAVIEIDPSRADAAVSLLGGDGNDALVVH CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEE GDVTCAATVASLAAQIGERFGALDVLVNNVGDFLRIAKPFELYDDAEIDSLYAVNLRHVF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHH SVTRAMLPLLRRSAAASIVSVSSIEGFRGIPNCSVYGAFKAALTGFTQSLALELAPSGIR HHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCEEHHHHHHHHHHHHHHHEEEECCCCEE VNLIAPETTETPQVPVSLVVAEEHRHHMPNWIPLGRFGTPRDIAEGIVFLAGPRASWITG EEEECCCCCCCCCCCEEEEEECHHHHCCCCEEECCCCCCHHHHHCCEEEEECCCCCCEEE TALHVNGGALAASGWYRDPKGNWTNMPVMVGNGMNL EEEEECCCEEEECCCCCCCCCCCCCCCEEECCCCCC >Mature Secondary Structure MDFQGKTVLITGGGAGIGLAAAQAFQEQGARVAVIEIDPSRADAAVSLLGGDGNDALVVH CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEE GDVTCAATVASLAAQIGERFGALDVLVNNVGDFLRIAKPFELYDDAEIDSLYAVNLRHVF CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHH SVTRAMLPLLRRSAAASIVSVSSIEGFRGIPNCSVYGAFKAALTGFTQSLALELAPSGIR HHHHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCEEHHHHHHHHHHHHHHHEEEECCCCEE VNLIAPETTETPQVPVSLVVAEEHRHHMPNWIPLGRFGTPRDIAEGIVFLAGPRASWITG EEEECCCCCCCCCCCEEEEEECHHHHCCCCEEECCCCCCHHHHHCCEEEEECCCCCCEEE TALHVNGGALAASGWYRDPKGNWTNMPVMVGNGMNL EEEEECCCEEEECCCCCCCCCCCCCCCEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]