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The map label for this gene is kshA [H]

Identifier: 73541266

GI number: 73541266

Start: 1698599

End: 1699675

Strand: Direct

Name: kshA [H]

Synonym: Reut_A1576

Alternate gene names: 73541266

Gene position: 1698599-1699675 (Clockwise)

Preceding gene: 73541265

Following gene: 73541270

Centisome position: 44.62

GC content: 64.25

Gene sequence:

>1077_bases
ATGACAACTACCGGCTACAAGATCGAAACGCGCCCGCTCGAGGCCCGCTACGCGCGAGGCTGGCACTGCCTGGGACTGGC
CGATGATTATCGCGACGGCAAGCCGCATACGCTGAACATCTTCGGCAAGCGCCTGGCGGCGTTTGCAGACTCGACGGGCG
CTATCCGCATCGTCGACAGCTATTGCCCGCATATGGGGGCCGACCTCAGCACCGGCACCGTGCAGGGCGACAACCTGGTC
TGCCCGTTCCACGGCTGGCAATGGGGCGGCGACGGCGGTTGCAAGTCGATTCCGTACTGCAAGCGCGTGCCGCCCAAGGC
CCGCATCGGCAGCTGGGAGACTAGCGAGCAGAACCGGCTGCTGTTCGTCTGGCACGATCCGGAAGGCCGTCCGGCGCCGC
GGGAGGTCGCCATTCCGCGCATCGACGCCTGCTTTGCGGCGGACTGGTCGGACTGGGCCATGGACAAGATGCTGATCGGC
ACCAACTGCCGCGAGCTCGTCGACAATATCTCCGACATGGCGCATTTCGGCACCGTGCACGGCGCTCCGGTGGATTACTT
CGCCAACCTGTTCGAACACCACAAGGCCACGCAGCTGATGATCGGGCGCAGCGCCCGGCTGTCGGGTGACTCGCGGCTGA
CCGCGCACTCGACGTATTTCGGCCCGGCGTACCACATCACCGAGATGACGGGAAAGATGGGCGACCAGGAGATCCACTCG
ATCCTGCTCAACTGCCATGTGCCGATCGACCTGAACAGCTTCGAGCTGCGCTACGGTGTGCTGGTCAAGAAGATACCGGG
CCTGTCGGACGAGCAGAACCGCGCCGTGGCGCAAGCCTATGTAGAGCAGGCACGTGAGGCCTTCTACGAGGATGTGGCGA
TCTGGGATAGCAAGATCCGCATCGACAATCCGCTGCTGTGCGAGGGCGACGGCCCCATCTACCAGATGCGTGACTGGTAC
CAGCAGTTCTACACCGATGTGGAACAGGTGCGCCCCGCCAGCGTGGCGCGACGGGTGTTCGAGCTGAATCCTGGCGGCAT
CGAACCGCCAACGCTGGGGCACGTGTTCGAGGCTTGA

Upstream 100 bases:

>100_bases
CCGTGAAGGCGCACACAGAGCCTAGTCTGATGGGACGATGAGCGGCGTGCGCGCGCCTCGTATCGTGAAGCATCCACAGA
GATCCAAGGAGACTGACGCC

Downstream 100 bases:

>100_bases
GGCCTGAAGCTGGTGGCCAGGAGGGAGACGAAATGCGCGAAGGCGCATTTCGCCTTTTTCCGCTTAGCGTTGCGAAGGAA
TATTGCCGCCGTCGACAACC

Product: Rieske (2Fe-2S) region

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTTTGYKIETRPLEARYARGWHCLGLADDYRDGKPHTLNIFGKRLAAFADSTGAIRIVDSYCPHMGADLSTGTVQGDNLV
CPFHGWQWGGDGGCKSIPYCKRVPPKARIGSWETSEQNRLLFVWHDPEGRPAPREVAIPRIDACFAADWSDWAMDKMLIG
TNCRELVDNISDMAHFGTVHGAPVDYFANLFEHHKATQLMIGRSARLSGDSRLTAHSTYFGPAYHITEMTGKMGDQEIHS
ILLNCHVPIDLNSFELRYGVLVKKIPGLSDEQNRAVAQAYVEQAREAFYEDVAIWDSKIRIDNPLLCEGDGPIYQMRDWY
QQFYTDVEQVRPASVARRVFELNPGGIEPPTLGHVFEA

Sequences:

>Translated_358_residues
MTTTGYKIETRPLEARYARGWHCLGLADDYRDGKPHTLNIFGKRLAAFADSTGAIRIVDSYCPHMGADLSTGTVQGDNLV
CPFHGWQWGGDGGCKSIPYCKRVPPKARIGSWETSEQNRLLFVWHDPEGRPAPREVAIPRIDACFAADWSDWAMDKMLIG
TNCRELVDNISDMAHFGTVHGAPVDYFANLFEHHKATQLMIGRSARLSGDSRLTAHSTYFGPAYHITEMTGKMGDQEIHS
ILLNCHVPIDLNSFELRYGVLVKKIPGLSDEQNRAVAQAYVEQAREAFYEDVAIWDSKIRIDNPLLCEGDGPIYQMRDWY
QQFYTDVEQVRPASVARRVFELNPGGIEPPTLGHVFEA
>Mature_357_residues
TTTGYKIETRPLEARYARGWHCLGLADDYRDGKPHTLNIFGKRLAAFADSTGAIRIVDSYCPHMGADLSTGTVQGDNLVC
PFHGWQWGGDGGCKSIPYCKRVPPKARIGSWETSEQNRLLFVWHDPEGRPAPREVAIPRIDACFAADWSDWAMDKMLIGT
NCRELVDNISDMAHFGTVHGAPVDYFANLFEHHKATQLMIGRSARLSGDSRLTAHSTYFGPAYHITEMTGKMGDQEIHSI
LLNCHVPIDLNSFELRYGVLVKKIPGLSDEQNRAVAQAYVEQAREAFYEDVAIWDSKIRIDNPLLCEGDGPIYQMRDWYQ
QFYTDVEQVRPASVARRVFELNPGGIEPPTLGHVFEA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=343, Percent_Identity=24.4897959183673, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161085896, Length=335, Percent_Identity=25.0746268656716, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: 1.14.1.- [C]

Molecular weight: Translated: 40222; Mature: 40091

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTGYKIETRPLEARYARGWHCLGLADDYRDGKPHTLNIFGKRLAAFADSTGAIRIVDS
CCCCCCEEECCCCHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEHH
YCPHMGADLSTGTVQGDNLVCPFHGWQWGGDGGCKSIPYCKRVPPKARIGSWETSEQNRL
HCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEE
LFVWHDPEGRPAPREVAIPRIDACFAADWSDWAMDKMLIGTNCRELVDNISDMAHFGTVH
EEEEECCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
GAPVDYFANLFEHHKATQLMIGRSARLSGDSRLTAHSTYFGPAYHITEMTGKMGDQEIHS
CCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEECCCCCCEEEEHHHHHCCCHHHHHH
ILLNCHVPIDLNSFELRYGVLVKKIPGLSDEQNRAVAQAYVEQAREAFYEDVAIWDSKIR
HHHHCCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IDNPLLCEGDGPIYQMRDWYQQFYTDVEQVRPASVARRVFELNPGGIEPPTLGHVFEA
ECCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
TTTGYKIETRPLEARYARGWHCLGLADDYRDGKPHTLNIFGKRLAAFADSTGAIRIVDS
CCCCCEEECCCCHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEHH
YCPHMGADLSTGTVQGDNLVCPFHGWQWGGDGGCKSIPYCKRVPPKARIGSWETSEQNRL
HCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEE
LFVWHDPEGRPAPREVAIPRIDACFAADWSDWAMDKMLIGTNCRELVDNISDMAHFGTVH
EEEEECCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
GAPVDYFANLFEHHKATQLMIGRSARLSGDSRLTAHSTYFGPAYHITEMTGKMGDQEIHS
CCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEECCCCCCEEEEHHHHHCCCHHHHHH
ILLNCHVPIDLNSFELRYGVLVKKIPGLSDEQNRAVAQAYVEQAREAFYEDVAIWDSKIR
HHHHCCCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IDNPLLCEGDGPIYQMRDWYQQFYTDVEQVRPASVARRVFELNPGGIEPPTLGHVFEA
ECCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA