The gene/protein map for NC_007347 is currently unavailable.
Definition Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession NC_007347
Length 3,806,533

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The map label for this gene is fabG2 [H]

Identifier: 73541260

GI number: 73541260

Start: 1691100

End: 1691912

Strand: Direct

Name: fabG2 [H]

Synonym: Reut_A1570

Alternate gene names: 73541260

Gene position: 1691100-1691912 (Clockwise)

Preceding gene: 73541259

Following gene: 73541261

Centisome position: 44.43

GC content: 68.63

Gene sequence:

>813_bases
ATGACCCCGAACACCGAAACCATTGACCTGCCGGCCGCGCCGGCCTACGTACCGGGCCACCAGCTGCTTGCCGGCAAGAG
CGTGCTCATCACCGCGGCTGCAGGCGCCGGCATCGGTTTCGCGGCCGCGCGCCGCTGCGCGGAGGAGGGCTGCCGCGCGC
TGATGATCTCCGATATCCACGAAAAGCGGCTGGAGGAGGCGGTCGCGAAGCTGCGCGCCGACACTGGCCTGCAGGCCATC
TATGGCCAGCTCTGCAATGTCGCGGACGACGTGCAGGTGCGCGCACTCGTGGCGGCGGCGGAGGAAGCGTTGGGCGGGAC
CGATGTGCTGATCAATAACGCGGGCCTGGGCGGCTCGCGCCGCCTAGTCGAGATGGACGATGCCGAGTGGTCGCGCGTGC
TCGATATTTCCCTCACGGGCACTTTCCGCATGACGCGGGCCATGCTGCCGCACATGCAGGCGCGGCGGCGCGGAGCCATC
GTCAACAACGCTTCGGTGTTGGGCTGGCGCGCGCAGAAAGAGCAGTCGCACTACGCCGCGGCCAAGGCCGGGGTGATGGC
GCTGACGCGCTGCAGCGCGATGGAGGCCGCCGAGTTCGGCGTACGCATCAACGCCGTGGCGCCCAGCATCGCGCTGCACG
ACTTCCTGAAGAAGTCGGCGCCGGCGGACCTGCTGCGGCAACTCAGCGAACGCGAAGCGTTCGGGCGAGCGGCCGAGGTG
TGGGAAGTGGCCAATGTGATGGTGTTCCTGGCGAGCGACTACGCCTCCTACATGACGGGCGAAGTGCTGCCGGTGAGCAG
CCAGCGGGCTTGA

Upstream 100 bases:

>100_bases
TCTCGCGCGCCGACACCATCTACGCCGGTACCAACGAAATCCAGCTCAACATCATCGCCGAGCGCGGACTCGGCATGCCC
CGCGAGGCAAGAGGACAGTC

Downstream 100 bases:

>100_bases
ATACAACAGGAAAGCAGATGTCACGAGTCTTCCGTTCCGCGCAGGACATCCACGACGCCGTCGGCCAGCGCCTCGGCGAA
AGCGCCTGGACGCGGATCAC

Product: short chain dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTPNTETIDLPAAPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDIHEKRLEEAVAKLRADTGLQAI
YGQLCNVADDVQVRALVAAAEEALGGTDVLINNAGLGGSRRLVEMDDAEWSRVLDISLTGTFRMTRAMLPHMQARRRGAI
VNNASVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEV
WEVANVMVFLASDYASYMTGEVLPVSSQRA

Sequences:

>Translated_270_residues
MTPNTETIDLPAAPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDIHEKRLEEAVAKLRADTGLQAI
YGQLCNVADDVQVRALVAAAEEALGGTDVLINNAGLGGSRRLVEMDDAEWSRVLDISLTGTFRMTRAMLPHMQARRRGAI
VNNASVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEV
WEVANVMVFLASDYASYMTGEVLPVSSQRA
>Mature_269_residues
TPNTETIDLPAAPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDIHEKRLEEAVAKLRADTGLQAIY
GQLCNVADDVQVRALVAAAEEALGGTDVLINNAGLGGSRRLVEMDDAEWSRVLDISLTGTFRMTRAMLPHMQARRRGAIV
NNASVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVW
EVANVMVFLASDYASYMTGEVLPVSSQRA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.258064516129, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=31.3253012048193, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI15277342, Length=159, Percent_Identity=32.0754716981132, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI40254992, Length=229, Percent_Identity=31.0043668122271, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=30.1526717557252, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=32.1608040201005, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=29.8804780876494, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=31.4606741573034, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=32.4468085106383, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=183, Percent_Identity=28.9617486338798, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=220, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=26.984126984127, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=28.5140562248996, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI83715985, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503301, Length=203, Percent_Identity=26.1083743842365, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7657478, Length=223, Percent_Identity=29.1479820627803, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=29.7979797979798, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI44680136, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI44680133, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI17738292, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=33.8709677419355, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=24.7967479674797, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=28.0487804878049, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=25.390625, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=30.1652892561983, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=28.0632411067194, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788459, Length=164, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=30.3643724696356, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=28.7937743190661, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=28.3400809716599, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=31.0756972111554, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=28.735632183908, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.1124497991968, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=28.515625, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=27.5193798449612, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=28.494623655914, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=254, Percent_Identity=27.5590551181102, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=254, Percent_Identity=26.3779527559055, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=252, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=27.0916334661355, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=26.4367816091954, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=178, Percent_Identity=25.8426966292135, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=26.3779527559055, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=208, Percent_Identity=29.8076923076923, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=222, Percent_Identity=28.3783783783784, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=27.6, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=229, Percent_Identity=24.0174672489083, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=31.3492063492063, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=32.7935222672065, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.2252964426877, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=32.2709163346614, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=29.9595141700405, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=29.8429319371728, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=27.5590551181102, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221331218, Length=211, Percent_Identity=28.436018957346, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24649181, Length=218, Percent_Identity=27.0642201834862, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=217, Percent_Identity=27.6497695852535, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356301, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=169, Percent_Identity=28.9940828402367, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28793; Mature: 28662

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTPNTETIDLPAAPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDIH
CCCCCCEEECCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHH
EKRLEEAVAKLRADTGLQAIYGQLCNVADDVQVRALVAAAEEALGGTDVLINNAGLGGSR
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
RLVEMDDAEWSRVLDISLTGTFRMTRAMLPHMQARRRGAIVNNASVLGWRAQKEQSHYAA
EEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEECCCCEEEEEHHHHHHHHHH
AKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEV
HHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
WEVANVMVFLASDYASYMTGEVLPVSSQRA
HHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
TPNTETIDLPAAPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDIH
CCCCCEEECCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHH
EKRLEEAVAKLRADTGLQAIYGQLCNVADDVQVRALVAAAEEALGGTDVLINNAGLGGSR
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
RLVEMDDAEWSRVLDISLTGTFRMTRAMLPHMQARRRGAIVNNASVLGWRAQKEQSHYAA
EEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEECCCCEEEEEHHHHHHHHHH
AKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEV
HHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
WEVANVMVFLASDYASYMTGEVLPVSSQRA
HHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]