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The map label for this gene is fadE25 [H]

Identifier: 73541259

GI number: 73541259

Start: 1689892

End: 1691103

Strand: Direct

Name: fadE25 [H]

Synonym: Reut_A1569

Alternate gene names: 73541259

Gene position: 1689892-1691103 (Clockwise)

Preceding gene: 73541258

Following gene: 73541260

Centisome position: 44.39

GC content: 70.13

Gene sequence:

>1212_bases
ATGAACACGAACGAAGACGCGGCATTTCGTGCCGAGGTAGCGGGGTGGATGTCCGCCAATCTGGCCGGAGAGTTCGCCTG
CCTGCAACACCGCGGCGGGCCCGGTGACGAGGAGGCTTACCCCGAACTGCGCAAGGCCTGGGAGCGGCGCCTCGCTGAAG
GCGGCTGGACCGGGCTCGGCTGGCCCGGCGCGCACGGCGGGCGCGAGCTGCCGGTGATGCAGCAGGTGATCTTCCATGAG
GAATACGCGCGCGCCGGCGGCCCGGGCCGCATGGGGCATATCGGCGAGGGACTGATCGGCCCGACGCTGATCGCCTTCGG
GTCGGAGGACCAGAAAGCGCGCCTGTTGCCGGGCATCCGCAACGGCACGACCTTCTGGTGCCAGGGCTATTCGGAGCCAG
GCGCGGGCTCGGACCTCGCCAATGTGCGCACGCGCGCGGTACGCGACGCGGCCACCGGCGACTGGCTGGTGAGCGGGCAG
AAGGTGTGGACCTCGCTCGCGCACGAATCCACCTGGATCTTCGTGCTGGCGCGTTGCGAGCCCGGTTCGCACGGCAGCAA
GGGCCTGATCTTCCTGATGCTGCCGCTGGACCAGCCCGGCATCGAGATCCGGCCGATCCGGCAGATGGGCGGTGGTGCGG
AATTCAACGAGGTGTTCTTCGACGGCGCACGCGCGGCGGCCGCCGACGTTCTCGGCGAGCCCGGCGACGGCTGGCGCATC
GCCATGGCGCTGCTCGGGTTCGAGCGCGGCATCTCCACGCTGGGCCAGCAGATGCAGTTCACGCATGAACTGGAATGGGT
CGCGCAGGCCGCGCGAGACAACGGCAGCAGCCGCGATGCGGTGGTGCGCCAGCGTATCGCGCGCGCCTGGGCCGGCCTGC
GCGTGATGCGCGCCAACGCGCTGCGCATGCTGGCCGGCGCGGCGCAAGCCGGTGCCGACGGCGGCGCCACGCTGCAGCGC
GAGGCGCTGATCTACAAGTACTACTGGTCCAACTGGCACCGCGACCTCGGGCAACTGGCGCTGGACGTGCTGGGCCCGCT
AGCCAACGTGCTCGATGCCGGCGAGGCGGGCGATGTGCGCCGCACGCGGCTGCAGCAGATGGCGCTGTTCTCGCGCGCCG
ACACCATCTACGCCGGTACCAACGAAATCCAGCTCAACATCATCGCCGAGCGCGGACTCGGCATGCCCCGCGAGGCAAGA
GGACAGTCATGA

Upstream 100 bases:

>100_bases
AGGCGGCCAGCCACTGGCTCGGCGGGGCGGGCGTGGCACTCGATTACATCGCCGATGTTTCCCAAGACGCGGATAGCGAG
CCGGGCGCGGGGAGGACAGC

Downstream 100 bases:

>100_bases
CCCCGAACACCGAAACCATTGACCTGCCGGCCGCGCCGGCCTACGTACCGGGCCACCAGCTGCTTGCCGGCAAGAGCGTG
CTCATCACCGCGGCTGCAGG

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNTNEDAAFRAEVAGWMSANLAGEFACLQHRGGPGDEEAYPELRKAWERRLAEGGWTGLGWPGAHGGRELPVMQQVIFHE
EYARAGGPGRMGHIGEGLIGPTLIAFGSEDQKARLLPGIRNGTTFWCQGYSEPGAGSDLANVRTRAVRDAATGDWLVSGQ
KVWTSLAHESTWIFVLARCEPGSHGSKGLIFLMLPLDQPGIEIRPIRQMGGGAEFNEVFFDGARAAAADVLGEPGDGWRI
AMALLGFERGISTLGQQMQFTHELEWVAQAARDNGSSRDAVVRQRIARAWAGLRVMRANALRMLAGAAQAGADGGATLQR
EALIYKYYWSNWHRDLGQLALDVLGPLANVLDAGEAGDVRRTRLQQMALFSRADTIYAGTNEIQLNIIAERGLGMPREAR
GQS

Sequences:

>Translated_403_residues
MNTNEDAAFRAEVAGWMSANLAGEFACLQHRGGPGDEEAYPELRKAWERRLAEGGWTGLGWPGAHGGRELPVMQQVIFHE
EYARAGGPGRMGHIGEGLIGPTLIAFGSEDQKARLLPGIRNGTTFWCQGYSEPGAGSDLANVRTRAVRDAATGDWLVSGQ
KVWTSLAHESTWIFVLARCEPGSHGSKGLIFLMLPLDQPGIEIRPIRQMGGGAEFNEVFFDGARAAAADVLGEPGDGWRI
AMALLGFERGISTLGQQMQFTHELEWVAQAARDNGSSRDAVVRQRIARAWAGLRVMRANALRMLAGAAQAGADGGATLQR
EALIYKYYWSNWHRDLGQLALDVLGPLANVLDAGEAGDVRRTRLQQMALFSRADTIYAGTNEIQLNIIAERGLGMPREAR
GQS
>Mature_403_residues
MNTNEDAAFRAEVAGWMSANLAGEFACLQHRGGPGDEEAYPELRKAWERRLAEGGWTGLGWPGAHGGRELPVMQQVIFHE
EYARAGGPGRMGHIGEGLIGPTLIAFGSEDQKARLLPGIRNGTTFWCQGYSEPGAGSDLANVRTRAVRDAATGDWLVSGQ
KVWTSLAHESTWIFVLARCEPGSHGSKGLIFLMLPLDQPGIEIRPIRQMGGGAEFNEVFFDGARAAAADVLGEPGDGWRI
AMALLGFERGISTLGQQMQFTHELEWVAQAARDNGSSRDAVVRQRIARAWAGLRVMRANALRMLAGAAQAGADGGATLQR
EALIYKYYWSNWHRDLGQLALDVLGPLANVLDAGEAGDVRRTRLQQMALFSRADTIYAGTNEIQLNIIAERGLGMPREAR
GQS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=24.5742092457421, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=26.3707571801567, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557233, Length=341, Percent_Identity=26.099706744868, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4557235, Length=383, Percent_Identity=26.3707571801567, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4557231, Length=359, Percent_Identity=24.7910863509749, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI187960098, Length=359, Percent_Identity=24.7910863509749, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI226958412, Length=231, Percent_Identity=25.5411255411255, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4501857, Length=321, Percent_Identity=26.1682242990654, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI226958414, Length=245, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361497, Length=373, Percent_Identity=25.4691689008043, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=22.9974160206718, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786223, Length=350, Percent_Identity=22.8571428571429, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=358, Percent_Identity=25.6983240223464, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=257, Percent_Identity=26.8482490272374, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=212, Percent_Identity=26.8867924528302, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=193, Percent_Identity=28.4974093264249, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=25.8152173913043, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=200, Percent_Identity=25.5, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=196, Percent_Identity=27.5510204081633, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=155, Percent_Identity=28.3870967741935, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=229, Percent_Identity=24.4541484716157, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=23.1404958677686, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=211, Percent_Identity=30.8056872037915, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=26.8698060941828, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363737, Length=302, Percent_Identity=23.5099337748344, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646207, Length=360, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43707; Mature: 43707

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNEDAAFRAEVAGWMSANLAGEFACLQHRGGPGDEEAYPELRKAWERRLAEGGWTGLG
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
WPGAHGGRELPVMQQVIFHEEYARAGGPGRMGHIGEGLIGPTLIAFGSEDQKARLLPGIR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCC
NGTTFWCQGYSEPGAGSDLANVRTRAVRDAATGDWLVSGQKVWTSLAHESTWIFVLARCE
CCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCEEEEEEEECC
PGSHGSKGLIFLMLPLDQPGIEIRPIRQMGGGAEFNEVFFDGARAAAADVLGEPGDGWRI
CCCCCCCCEEEEEEECCCCCCEEEEHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHH
AMALLGFERGISTLGQQMQFTHELEWVAQAARDNGSSRDAVVRQRIARAWAGLRVMRANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRMLAGAAQAGADGGATLQREALIYKYYWSNWHRDLGQLALDVLGPLANVLDAGEAGDVR
HHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RTRLQQMALFSRADTIYAGTNEIQLNIIAERGLGMPREARGQS
HHHHHHHHHHHHCCEEEECCCEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNTNEDAAFRAEVAGWMSANLAGEFACLQHRGGPGDEEAYPELRKAWERRLAEGGWTGLG
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
WPGAHGGRELPVMQQVIFHEEYARAGGPGRMGHIGEGLIGPTLIAFGSEDQKARLLPGIR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCC
NGTTFWCQGYSEPGAGSDLANVRTRAVRDAATGDWLVSGQKVWTSLAHESTWIFVLARCE
CCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCEEEEEEEECC
PGSHGSKGLIFLMLPLDQPGIEIRPIRQMGGGAEFNEVFFDGARAAAADVLGEPGDGWRI
CCCCCCCCEEEEEEECCCCCCEEEEHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCCHHH
AMALLGFERGISTLGQQMQFTHELEWVAQAARDNGSSRDAVVRQRIARAWAGLRVMRANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRMLAGAAQAGADGGATLQREALIYKYYWSNWHRDLGQLALDVLGPLANVLDAGEAGDVR
HHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RTRLQQMALFSRADTIYAGTNEIQLNIIAERGLGMPREARGQS
HHHHHHHHHHHHCCEEEECCCEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]