BacMap

Definition	Ralstonia eutropha JMP134 chromosome 1, complete sequence.
Accession	NC_007347
Length	3,806,533

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The map label for this gene is ephD [H]

Identifier: 73541228

GI number: 73541228

Start: 1657094

End: 1657903

Strand: Reverse

Name: ephD [H]

Synonym: Reut_A1538

Alternate gene names: 73541228

Gene position: 1657903-1657094 (Counterclockwise)

Preceding gene: 73541230

Following gene: 73541227

Centisome position: 43.55

GC content: 70.37

Gene sequence:

>810_bases
ATGGCGGCAAATCCGCGGCAGCAGGCCGCAGTGATCACCGGAGCGGCCAGCGGCATCGGCTGCGCGCTCGCGCAGGCCCT
CGCGGCGCAAGGGTATGCGCTGGCGCTCGCCGATATCGACGCCAATGCGCTCGAAGCGGCACGCGCGGCGCTCGCCGGGC
AAGGGGCGACCGTCATCGCCATCCCCACCGACGTGTCCGACGCCGCGCAGATCGAGCACCTGTGCGAAGAGAGCTTCCGG
CGGCTGGGCCGTGTCGACCTGCTGGTCAACAACGCAGGCATTCTCGCGACCGGCCGCTGCTGGGAACTGGAGCCGGAGGT
GTTCGAGCGTGTGTTGCGCGTCAATCTGTGGAGCGTACTGCACGCGCTGCGCAACTTCGTGCCCCGCATGGCGGAACAGG
GTTCAGGCCATATCGTCAACGTGGCGTCGATGGCAGGCCTCGCGGTAGGACCGTGGCTGGCGCCGTACACGCTGTCCAAG
CAGGGCGTGGTGGCGCTCAGCGAAGGGCTGCTGCTCGAACTGCAAGCGGCGGGGATACCGCTGGGCGTATCGGTGGTCTG
CCCAGGTCCGGTCGCCACCGGCATCGCGGCGGGACTTGGCGGCACGGCGCAGCAGGAGGTGGACCAGATGAACGGCGCGC
TGCGCAACGGCATTGCCGCGGGCATGACGCCCGATGCCGTCGCGCAGCGGATCCTCGACGGCGTGTCGGCGGGCCAGTTC
TGGATCCTGCCGCACGAGCAGGCCGCCCAAGCCGCGCTCGTACGCGCGCAAGGCATTGCCGCCGGCAAGGCGCCCGCCTT
CGCGCTCTGA

Upstream 100 bases:

>100_bases
CGCCCTACCCAAACAGACGATGCCGTGCCGCCGCGCTGCCGCTACAAGACAGCCATGCGCGGCGATTTCCGCCGCCTTCT
TTTCACCGAGGAGCAACACC

Downstream 100 bases:

>100_bases
CCATCATCACCCCAAGTTACTCAGGAGACCCGATGCCGCTCGATCCCCAGGCCCGCGCCATGCTGGACGCCATGGCCGCC
ATGCCGAGTCCCGACTTCAC

Product: Short-chain dehydrogenase/reductase SDR:glucose/ribitol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAANPRQQAAVITGAASGIGCALAQALAAQGYALALADIDANALEAARAALAGQGATVIAIPTDVSDAAQIEHLCEESFR
RLGRVDLLVNNAGILATGRCWELEPEVFERVLRVNLWSVLHALRNFVPRMAEQGSGHIVNVASMAGLAVGPWLAPYTLSK
QGVVALSEGLLLELQAAGIPLGVSVVCPGPVATGIAAGLGGTAQQEVDQMNGALRNGIAAGMTPDAVAQRILDGVSAGQF
WILPHEQAAQAALVRAQGIAAGKAPAFAL

Sequences:

>Translated_269_residues
MAANPRQQAAVITGAASGIGCALAQALAAQGYALALADIDANALEAARAALAGQGATVIAIPTDVSDAAQIEHLCEESFR
RLGRVDLLVNNAGILATGRCWELEPEVFERVLRVNLWSVLHALRNFVPRMAEQGSGHIVNVASMAGLAVGPWLAPYTLSK
QGVVALSEGLLLELQAAGIPLGVSVVCPGPVATGIAAGLGGTAQQEVDQMNGALRNGIAAGMTPDAVAQRILDGVSAGQF
WILPHEQAAQAALVRAQGIAAGKAPAFAL
>Mature_268_residues
AANPRQQAAVITGAASGIGCALAQALAAQGYALALADIDANALEAARAALAGQGATVIAIPTDVSDAAQIEHLCEESFRR
LGRVDLLVNNAGILATGRCWELEPEVFERVLRVNLWSVLHALRNFVPRMAEQGSGHIVNVASMAGLAVGPWLAPYTLSKQ
GVVALSEGLLLELQAAGIPLGVSVVCPGPVATGIAAGLGGTAQQEVDQMNGALRNGIAAGMTPDAVAQRILDGVSAGQFW
ILPHEQAAQAALVRAQGIAAGKAPAFAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=250, Percent_Identity=29.6, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI210032110, Length=255, Percent_Identity=30.1960784313725, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=30.6878306878307, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI20149619, Length=236, Percent_Identity=29.6610169491525, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40254992, Length=188, Percent_Identity=35.1063829787234, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4503817, Length=235, Percent_Identity=28.0851063829787, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40807363, Length=203, Percent_Identity=31.5270935960591, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=33.8461538461538, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI32483357, Length=212, Percent_Identity=28.3018867924528, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI25282469, Length=217, Percent_Identity=30.4147465437788, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=33.7349397590361, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=32.6829268292683, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.021978021978, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI109715829, Length=254, Percent_Identity=28.740157480315, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI310128830, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI310115468, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=30.8900523560209, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=170, Percent_Identity=33.5294117647059, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI223718074, Length=216, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032112, Length=183, Percent_Identity=31.1475409836066, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI19743808, Length=238, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI126723750, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=200, Percent_Identity=30.5, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=30.6122448979592, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790717, Length=189, Percent_Identity=30.6878306878307, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=138, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789378, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87082160, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=201, Percent_Identity=33.8308457711443, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786812, Length=227, Percent_Identity=29.0748898678414, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789057, Length=177, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788459, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786701, Length=229, Percent_Identity=27.0742358078603, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=199, Percent_Identity=32.1608040201005, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=28.5, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=32.8125, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17508895, Length=240, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=239, Percent_Identity=29.2887029288703, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=30, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=196, Percent_Identity=32.6530612244898, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=237, Percent_Identity=28.2700421940928, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=173, Percent_Identity=30.0578034682081, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=242, Percent_Identity=27.6859504132231, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=201, Percent_Identity=29.3532338308458, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=188, Percent_Identity=34.0425531914894, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=218, Percent_Identity=26.1467889908257, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=238, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=250, Percent_Identity=28, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=201, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=238, Percent_Identity=31.5126050420168, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=238, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=31.1881188118812, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=235, Percent_Identity=26.8085106382979, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=208, Percent_Identity=26.4423076923077, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=220, Percent_Identity=27.7272727272727, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=238, Percent_Identity=24.3697478991597, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=188, Percent_Identity=31.9148936170213, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=191, Percent_Identity=24.6073298429319, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.6875, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=29.0816326530612, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=213, Percent_Identity=34.2723004694836, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24581726, Length=241, Percent_Identity=28.2157676348548, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.9842931937173, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=33.4975369458128, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=31.6582914572864, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281364892, Length=236, Percent_Identity=29.6610169491525, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649181, Length=235, Percent_Identity=28.0851063829787, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=235, Percent_Identity=27.6595744680851, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=32.4742268041237, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=27.979274611399, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=29.1457286432161, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=29.1457286432161, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24663911, Length=199, Percent_Identity=31.1557788944724, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571387, Length=256, Percent_Identity=30.078125, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=29, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=29, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648693, Length=197, Percent_Identity=31.9796954314721, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355889, Length=197, Percent_Identity=31.9796954314721, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221510726, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=28.6486486486486, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24639444, Length=205, Percent_Identity=27.8048780487805, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356301, Length=250, Percent_Identity=25.6, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644337, Length=182, Percent_Identity=29.6703296703297, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007234, Length=199, Percent_Identity=31.6582914572864, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364494, Length=202, Percent_Identity=29.7029702970297, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27386; Mature: 27255

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANPRQQAAVITGAASGIGCALAQALAAQGYALALADIDANALEAARAALAGQGATVIA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCEEEE
IPTDVSDAAQIEHLCEESFRRLGRVDLLVNNAGILATGRCWELEPEVFERVLRVNLWSVL
ECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCEECCHHHHHHHHHHHHHHHH
HALRNFVPRMAEQGSGHIVNVASMAGLAVGPWLAPYTLSKQGVVALSEGLLLELQAAGIP
HHHHHHHHHHHHCCCCCEEEHHHHCCHHHCCCCCCEEECCCCEEEECCCCEEEEECCCCC
LGVSVVCPGPVATGIAAGLGGTAQQEVDQMNGALRNGIAAGMTPDAVAQRILDGVSAGQF
CCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEE
WILPHEQAAQAALVRAQGIAAGKAPAFAL
EEECCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AANPRQQAAVITGAASGIGCALAQALAAQGYALALADIDANALEAARAALAGQGATVIA
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCEEEE
IPTDVSDAAQIEHLCEESFRRLGRVDLLVNNAGILATGRCWELEPEVFERVLRVNLWSVL
ECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCEECCHHHHHHHHHHHHHHHH
HALRNFVPRMAEQGSGHIVNVASMAGLAVGPWLAPYTLSKQGVVALSEGLLLELQAAGIP
HHHHHHHHHHHHCCCCCEEEHHHHCCHHHCCCCCCEEECCCCEEEECCCCEEEEECCCCC
LGVSVVCPGPVATGIAAGLGGTAQQEVDQMNGALRNGIAAGMTPDAVAQRILDGVSAGQF
CCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEE
WILPHEQAAQAALVRAQGIAAGKAPAFAL
EEECCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]