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The map label for this gene is qseC [H]

Identifier: 73541032

GI number: 73541032

Start: 1436540

End: 1437898

Strand: Direct

Name: qseC [H]

Synonym: Reut_A1338

Alternate gene names: 73541032

Gene position: 1436540-1437898 (Clockwise)

Preceding gene: 73541031

Following gene: 73541034

Centisome position: 37.74

GC content: 65.42

Gene sequence:

>1359_bases
ATGACGCTGCAGCGGCGCCTGATCCTGGCCGTGCTGATCGCGGCCCCGGTGGTGTGGCTGCTGACCATCGGCATGACCTA
CGTGCGTGCGCGCCACGAAATCAACGAGTTGTACGACACTGACATGGTGCGCATGGCGATGCAGATGCATTCGCTGGTGC
CGCTGGTCGACATCACCGCCGCGCCGTCGCGGGCACGGCTGCCGGCTGCGGCGGAAGGCGATCAGGGCGATGCAGGCCTC
GGCGACATGGCTATTGCTGCCTGGCTGCCCGATGGCACGCCCATGCACATCGATCCGGACGGGGATCGCCTGCCGCCCGC
GCAAGGCGTGAAGGGCTTTACCGACCGGCGCATCGACGGCCATCGCTGGCGCTTGTATTACCTGGATGACGACGTCAGCG
GCTGGCGTGTTTGCATCGGCCAGAAGCTGGGCGAGCGCAACGAGCTGATCCTGTCCTATATCGCGGCACAGGTGCTGCCG
TGGGCGGTGGGCCTGCCCGTGCTCATCGGTGTACTGATTCTGTTCATGCGGCGCGCGATGGCGCCCGTGCGGGAGCTTTC
CGCAGAAATCGAGAGCCGTTCTCCGCACGACCCGCGGCCATTGGGTCTGGCGGGCGTGCCCGGCGAACTGGTGCCGCTGG
TCAACGCCATGAACCGGCTGCTGGTGCGCGTCTCCGATTCGCTCGAGCACGAGCGGCGCCTTACGGCCGATGCCGCACAC
GAGATGCGCACGCCGCTGGCCGCGCTCAAGGCCCAGTGGGAAATCGCACGGCGCTCGCCGGACGAGAGCGAACGCGCCCG
CGCGCGTGCCAATGTGGAGTCCGGCATCGATCGCATGAGCCGGCTGGTGTCGCAGTTGCTGACCATGAGCCGGCTCGAAG
ATGCGTCGGAGCTGGCCTTGCTGGAAGACGTGAACTGGCAATCGATTGCGCAGCAGGCGCTGTCGGATTGCCTCGCTTTG
GCGCAGCGCAGGAAGATCGATGTGGAATTGATCTGGCCATCAGCGCACATAGCGCCGCTTCCGTTGGCGGGCGACCCGAA
TCTGCTTGGGCTGATGCTGCGGAATCTGCTGGACAATGCGATTCGCTACAGCCCGGCGGGGGCGATGGTCACCATGGATT
TTCGGGCTGACGGCATTGTGGTGTGTGATGAGGGGCCTGGTGTGGCCCCTGAGGTGCTGGCACGGCTGGGTGATCGCTTT
TTTCGCGGAAGCGGCCAGCGCGAGCAGGGGCATGGGTTGGGGATTTCCATTGCGCAGCGCGTTGCGCGGTTGCATGGACT
GGCAATTACATTTGCGAATCGCGGCGATGGCCGCAACGGCCTGATGGTTCGCATCTTCCGTTGTGCCGGGCAGTCATAA

Upstream 100 bases:

>100_bases
TGGAGGTGCATATCCACCACCTGCGCCGCAAGATCCATCCGAAGATCGTCCGCACATTCCGTGGCGCGGGCTACACGCTC
GGTGCTGCCGAGGACTGCGC

Downstream 100 bases:

>100_bases
AAAACGCCCCGGGCGGCAGCAGCCGCGCGGGGCGTCCTTCAACAACAGTATTGGCCAGGCAGCTTAGCGCTTGAGCTTGG
CGAATGCCGCCGCCATGGCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTLQRRLILAVLIAAPVVWLLTIGMTYVRARHEINELYDTDMVRMAMQMHSLVPLVDITAAPSRARLPAAAEGDQGDAGL
GDMAIAAWLPDGTPMHIDPDGDRLPPAQGVKGFTDRRIDGHRWRLYYLDDDVSGWRVCIGQKLGERNELILSYIAAQVLP
WAVGLPVLIGVLILFMRRAMAPVRELSAEIESRSPHDPRPLGLAGVPGELVPLVNAMNRLLVRVSDSLEHERRLTADAAH
EMRTPLAALKAQWEIARRSPDESERARARANVESGIDRMSRLVSQLLTMSRLEDASELALLEDVNWQSIAQQALSDCLAL
AQRRKIDVELIWPSAHIAPLPLAGDPNLLGLMLRNLLDNAIRYSPAGAMVTMDFRADGIVVCDEGPGVAPEVLARLGDRF
FRGSGQREQGHGLGISIAQRVARLHGLAITFANRGDGRNGLMVRIFRCAGQS

Sequences:

>Translated_452_residues
MTLQRRLILAVLIAAPVVWLLTIGMTYVRARHEINELYDTDMVRMAMQMHSLVPLVDITAAPSRARLPAAAEGDQGDAGL
GDMAIAAWLPDGTPMHIDPDGDRLPPAQGVKGFTDRRIDGHRWRLYYLDDDVSGWRVCIGQKLGERNELILSYIAAQVLP
WAVGLPVLIGVLILFMRRAMAPVRELSAEIESRSPHDPRPLGLAGVPGELVPLVNAMNRLLVRVSDSLEHERRLTADAAH
EMRTPLAALKAQWEIARRSPDESERARARANVESGIDRMSRLVSQLLTMSRLEDASELALLEDVNWQSIAQQALSDCLAL
AQRRKIDVELIWPSAHIAPLPLAGDPNLLGLMLRNLLDNAIRYSPAGAMVTMDFRADGIVVCDEGPGVAPEVLARLGDRF
FRGSGQREQGHGLGISIAQRVARLHGLAITFANRGDGRNGLMVRIFRCAGQS
>Mature_451_residues
TLQRRLILAVLIAAPVVWLLTIGMTYVRARHEINELYDTDMVRMAMQMHSLVPLVDITAAPSRARLPAAAEGDQGDAGLG
DMAIAAWLPDGTPMHIDPDGDRLPPAQGVKGFTDRRIDGHRWRLYYLDDDVSGWRVCIGQKLGERNELILSYIAAQVLPW
AVGLPVLIGVLILFMRRAMAPVRELSAEIESRSPHDPRPLGLAGVPGELVPLVNAMNRLLVRVSDSLEHERRLTADAAHE
MRTPLAALKAQWEIARRSPDESERARARANVESGIDRMSRLVSQLLTMSRLEDASELALLEDVNWQSIAQQALSDCLALA
QRRKIDVELIWPSAHIAPLPLAGDPNLLGLMLRNLLDNAIRYSPAGAMVTMDFRADGIVVCDEGPGVAPEVLARLGDRFF
RGSGQREQGHGLGISIAQRVARLHGLAITFANRGDGRNGLMVRIFRCAGQS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=441, Percent_Identity=38.0952380952381, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1790551, Length=292, Percent_Identity=30.8219178082192, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786783, Length=286, Percent_Identity=31.4685314685315, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788279, Length=329, Percent_Identity=27.9635258358663, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790861, Length=289, Percent_Identity=29.4117647058824, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=28.0701754385965, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=202, Percent_Identity=30.1980198019802, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=29.5833333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=24.5689655172414, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49684; Mature: 49553

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQRRLILAVLIAAPVVWLLTIGMTYVRARHEINELYDTDMVRMAMQMHSLVPLVDITA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
APSRARLPAAAEGDQGDAGLGDMAIAAWLPDGTPMHIDPDGDRLPPAQGVKGFTDRRIDG
CCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
HRWRLYYLDDDVSGWRVCIGQKLGERNELILSYIAAQVLPWAVGLPVLIGVLILFMRRAM
CEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
APVRELSAEIESRSPHDPRPLGLAGVPGELVPLVNAMNRLLVRVSDSLEHERRLTADAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMRTPLAALKAQWEIARRSPDESERARARANVESGIDRMSRLVSQLLTMSRLEDASELAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEDVNWQSIAQQALSDCLALAQRRKIDVELIWPSAHIAPLPLAGDPNLLGLMLRNLLDNA
HHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IRYSPAGAMVTMDFRADGIVVCDEGPGVAPEVLARLGDRFFRGSGQREQGHGLGISIAQR
HHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VARLHGLAITFANRGDGRNGLMVRIFRCAGQS
HHHHHCEEEEEECCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TLQRRLILAVLIAAPVVWLLTIGMTYVRARHEINELYDTDMVRMAMQMHSLVPLVDITA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
APSRARLPAAAEGDQGDAGLGDMAIAAWLPDGTPMHIDPDGDRLPPAQGVKGFTDRRIDG
CCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
HRWRLYYLDDDVSGWRVCIGQKLGERNELILSYIAAQVLPWAVGLPVLIGVLILFMRRAM
CEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
APVRELSAEIESRSPHDPRPLGLAGVPGELVPLVNAMNRLLVRVSDSLEHERRLTADAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMRTPLAALKAQWEIARRSPDESERARARANVESGIDRMSRLVSQLLTMSRLEDASELAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEDVNWQSIAQQALSDCLALAQRRKIDVELIWPSAHIAPLPLAGDPNLLGLMLRNLLDNA
HHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IRYSPAGAMVTMDFRADGIVVCDEGPGVAPEVLARLGDRFFRGSGQREQGHGLGISIAQR
HHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VARLHGLAITFANRGDGRNGLMVRIFRCAGQS
HHHHHCEEEEEECCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]