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The map label for this gene is kup

Identifier: 73541028

GI number: 73541028

Start: 1430655

End: 1432565

Strand: Direct

Name: kup

Synonym: Reut_A1334

Alternate gene names: 73541028

Gene position: 1430655-1432565 (Clockwise)

Preceding gene: 73541027

Following gene: 73541031

Centisome position: 37.58

GC content: 62.53

Gene sequence:

>1911_bases
ATGACCACCCAATCCGCGACCACCGCCACTAGCCACTACTTTGTCGAGAATCCGAGCACGCGCGCGCTGGTGATCGGCGC
CATCGGTGTCGTCTTCGGCGACATCGGCACCAGTCCGCTGTATTCGCTCAAGGAGTGCTTCAGCAAGGAGCACGGCATCC
CGTTCAGTCCCGACGCCGTTCTGGGCATCATCTCGCTGCTGTTCTGGGCCATGACCATCGTGGTCTCGATCAAGTACGTG
GTGTTTGTGATGCGCGCCGACAACAACGGCGAAGGCGGGGTGCTGGCGCTGATGGCGCTGGTACTGCGCACGGCGGCGCC
ACGCTCGCGCTGGGCCAAGGTTCTGATGATGCTGGGCATCTTCGGGGCATGCATGTTCTATGGCGATGCGGTGATCACAC
CGGCCATTTCGGTGTTGTCCGCCGTGGAGGGGCTGGAAATTGCCACACCACAGCTCTCGCGGTTCGTGATCCCGATCACG
CTGGTCATTCTCGTGGCGCTATTCCTGATCCAGCGCAACGGCACATCGGTGGTGGGCAAGCTGTTCGGCCCGGTCATGGT
GGTCTGGTTCGTGACGCTGGGGCTGCTCGGGCTATACAACCTGGTGCAGGCGCCGGAGATCCTCAAGGCCTTCAACCCGT
ACTACGGGATCTCGTTCCTGATCGCGCATTCGCTGCAGGCCTTTATCGTGCTGGGCTCGGTATTCCTGGTGCTGACCGGG
GCGGAAGCCCTCTACGTCGACATGGGCCACTTCGGCGCGCGCCCGATCCGCTATGGCTGGTTCGTGCTGGTCATGCCGTG
CCTGATCCTGAACTACTTCGGCCAGGGCGCCATGCTGTTGACGAACCCGGCTGGGGCCGAAAACCCGTTCTACCTGATGG
TGCCGGAACCGCTGCTGATCCCGATGGTGGTGCTGGCGACCTGCGCCACGGTCATCGCCTCGCAGGCGGTGATCTCGGGC
GCATTCTCGCTGACCAGCCAGGCCATCCAGCTCGGCTTCGTGCCGCGCATGCGCGTGCGCTACACCTCGGCGGCCGAGAT
CGGGCAGATCTACCTGCCGGTCATCAACTGGATCCTGCTGGTGCTGGTCGTGGCCGTGGTGATCTCGTTCAAGAAGTCGG
AAAACCTGGCGGCGGCCTATGGCATTGCCGTGACCACGACCATGGTGATCACCACGTTCCTCGCGGCCGTGGTGATGCGC
AACGTCTGGAAGTGGAACCCGGCGCTCGTGACGCTGCTCGGCTTGTCGTTCCTGCTCGTGGACCTGGCATTCTTCGCGGC
GAACCTGCTGAAGGTTGCTGAAGGTGGCTGGTTCCCGCTGCTTCTCGGCAGCACAGCATTCTTCTTGCTGATGACGTGGT
ATAGCGGCCGCAAGCTGCTGCGTGCGCGCAGCCTCGAAGACGGCATTCCGCTGGAGCCGTTCATTGCCGGCCTGCTCGCA
CATCCGCCGCATCGCGTCGAGGGCACGGCGGTGTTCCTGACCGGCAATACCGAGTCGGTGCCGGTGTCGCTGTTGCACAA
CCTCAAGCACAACCGCGTGCTGCATGAGCGGGTGGTCTTCCTGAGCTTTGTCACGCGCGATATTCCGTATGTCGACGACG
AGCAACGCCTGAGCTGCAAGGACCTTGGCGGCGGTGTGTTCATCCTGAAGTCGGATTACGGTTTCAAGGAGACTCCTGAC
GTGCACAAGGTGCTGGACCTCGCGCAGCGCAAGCTGGGCATGCATTTCGAGCTGATGGAGACCTCGTTCTTCATCGCGCG
CGAATCGGTGATCCCGTCCAAGCTGCCGGGGATGTCGATGTGGCGCGAAAGCTTGTTCGCGTGGATGCATCAGAACGGCG
CCAAGCCGTCGGACTTCTTCCAGATTCCGGCCAACCGCGTGGTCGAACTCGGCACGAAGGTCGAAATCTGA

Upstream 100 bases:

>100_bases
CATCAGAAGAGGGAGGCGGCCAATCCGACGGCTGCTGTGTCTGGCCGGGTTTCGGGAGATCGATGTCTGCTCCGCGAACC
GGTCCCAAAGACCAGAATTC

Downstream 100 bases:

>100_bases
CGAGCCCGTGCAGGCAGTACGAAGCCCCCGCCAGGTGCGAACCTGCGGGGGCTTTGTCTTTGAGGCCGTTCACGCGGCCA
TGGCGGGTGACGACTGGAGA

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTTQSATTATSHYFVENPSTRALVIGAIGVVFGDIGTSPLYSLKECFSKEHGIPFSPDAVLGIISLLFWAMTIVVSIKYV
VFVMRADNNGEGGVLALMALVLRTAAPRSRWAKVLMMLGIFGACMFYGDAVITPAISVLSAVEGLEIATPQLSRFVIPIT
LVILVALFLIQRNGTSVVGKLFGPVMVVWFVTLGLLGLYNLVQAPEILKAFNPYYGISFLIAHSLQAFIVLGSVFLVLTG
AEALYVDMGHFGARPIRYGWFVLVMPCLILNYFGQGAMLLTNPAGAENPFYLMVPEPLLIPMVVLATCATVIASQAVISG
AFSLTSQAIQLGFVPRMRVRYTSAAEIGQIYLPVINWILLVLVVAVVISFKKSENLAAAYGIAVTTTMVITTFLAAVVMR
NVWKWNPALVTLLGLSFLLVDLAFFAANLLKVAEGGWFPLLLGSTAFFLLMTWYSGRKLLRARSLEDGIPLEPFIAGLLA
HPPHRVEGTAVFLTGNTESVPVSLLHNLKHNRVLHERVVFLSFVTRDIPYVDDEQRLSCKDLGGGVFILKSDYGFKETPD
VHKVLDLAQRKLGMHFELMETSFFIARESVIPSKLPGMSMWRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI

Sequences:

>Translated_636_residues
MTTQSATTATSHYFVENPSTRALVIGAIGVVFGDIGTSPLYSLKECFSKEHGIPFSPDAVLGIISLLFWAMTIVVSIKYV
VFVMRADNNGEGGVLALMALVLRTAAPRSRWAKVLMMLGIFGACMFYGDAVITPAISVLSAVEGLEIATPQLSRFVIPIT
LVILVALFLIQRNGTSVVGKLFGPVMVVWFVTLGLLGLYNLVQAPEILKAFNPYYGISFLIAHSLQAFIVLGSVFLVLTG
AEALYVDMGHFGARPIRYGWFVLVMPCLILNYFGQGAMLLTNPAGAENPFYLMVPEPLLIPMVVLATCATVIASQAVISG
AFSLTSQAIQLGFVPRMRVRYTSAAEIGQIYLPVINWILLVLVVAVVISFKKSENLAAAYGIAVTTTMVITTFLAAVVMR
NVWKWNPALVTLLGLSFLLVDLAFFAANLLKVAEGGWFPLLLGSTAFFLLMTWYSGRKLLRARSLEDGIPLEPFIAGLLA
HPPHRVEGTAVFLTGNTESVPVSLLHNLKHNRVLHERVVFLSFVTRDIPYVDDEQRLSCKDLGGGVFILKSDYGFKETPD
VHKVLDLAQRKLGMHFELMETSFFIARESVIPSKLPGMSMWRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI
>Mature_635_residues
TTQSATTATSHYFVENPSTRALVIGAIGVVFGDIGTSPLYSLKECFSKEHGIPFSPDAVLGIISLLFWAMTIVVSIKYVV
FVMRADNNGEGGVLALMALVLRTAAPRSRWAKVLMMLGIFGACMFYGDAVITPAISVLSAVEGLEIATPQLSRFVIPITL
VILVALFLIQRNGTSVVGKLFGPVMVVWFVTLGLLGLYNLVQAPEILKAFNPYYGISFLIAHSLQAFIVLGSVFLVLTGA
EALYVDMGHFGARPIRYGWFVLVMPCLILNYFGQGAMLLTNPAGAENPFYLMVPEPLLIPMVVLATCATVIASQAVISGA
FSLTSQAIQLGFVPRMRVRYTSAAEIGQIYLPVINWILLVLVVAVVISFKKSENLAAAYGIAVTTTMVITTFLAAVVMRN
VWKWNPALVTLLGLSFLLVDLAFFAANLLKVAEGGWFPLLLGSTAFFLLMTWYSGRKLLRARSLEDGIPLEPFIAGLLAH
PPHRVEGTAVFLTGNTESVPVSLLHNLKHNRVLHERVVFLSFVTRDIPYVDDEQRLSCKDLGGGVFILKSDYGFKETPDV
HKVLDLAQRKLGMHFELMETSFFIARESVIPSKLPGMSMWRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=618, Percent_Identity=50.1618122977346, Blast_Score=627, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_CUPPJ (Q472H9)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295548.1
- GeneID:   3611915
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A1334
- NMPDR:   fig|264198.3.peg.2048
- HOGENOM:   HBG351154
- OMA:   ETINIPR
- ProtClustDB:   CLSK897039
- BioCyc:   REUT264198:REUT_A1334-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69683; Mature: 69551

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf5ce9d0)-; HASH(0xeafe6fc)-; HASH(0xf833c5c)-; HASH(0xe320364)-; HASH(0x1021f2cc)-; HASH(0xc3d25dc)-; HASH(0x1021f050)-; HASH(0xfeb2348)-; HASH(0xf720584)-; HASH(0x101fbea0)-; HASH(0x10194aa4)-; HASH(0xeafe558)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQSATTATSHYFVENPSTRALVIGAIGVVFGDIGTSPLYSLKECFSKEHGIPFSPDAV
CCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHH
LGIISLLFWAMTIVVSIKYVVFVMRADNNGEGGVLALMALVLRTAAPRSRWAKVLMMLGI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGACMFYGDAVITPAISVLSAVEGLEIATPQLSRFVIPITLVILVALFLIQRNGTSVVGK
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LFGPVMVVWFVTLGLLGLYNLVQAPEILKAFNPYYGISFLIAHSLQAFIVLGSVFLVLTG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEALYVDMGHFGARPIRYGWFVLVMPCLILNYFGQGAMLLTNPAGAENPFYLMVPEPLLI
CHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCHHHH
PMVVLATCATVIASQAVISGAFSLTSQAIQLGFVPRMRVRYTSAAEIGQIYLPVINWILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHHHHH
VLVVAVVISFKKSENLAAAYGIAVTTTMVITTFLAAVVMRNVWKWNPALVTLLGLSFLLV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DLAFFAANLLKVAEGGWFPLLLGSTAFFLLMTWYSGRKLLRARSLEDGIPLEPFIAGLLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
HPPHRVEGTAVFLTGNTESVPVSLLHNLKHNRVLHERVVFLSFVTRDIPYVDDEQRLSCK
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DLGGGVFILKSDYGFKETPDVHKVLDLAQRKLGMHFELMETSFFIARESVIPSKLPGMSM
HCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCHHH
WRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI
HHHHHHHHHHHCCCCCCHHEECCHHHHHHCCCCCCH
>Mature Secondary Structure 
TTQSATTATSHYFVENPSTRALVIGAIGVVFGDIGTSPLYSLKECFSKEHGIPFSPDAV
CCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHH
LGIISLLFWAMTIVVSIKYVVFVMRADNNGEGGVLALMALVLRTAAPRSRWAKVLMMLGI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGACMFYGDAVITPAISVLSAVEGLEIATPQLSRFVIPITLVILVALFLIQRNGTSVVGK
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LFGPVMVVWFVTLGLLGLYNLVQAPEILKAFNPYYGISFLIAHSLQAFIVLGSVFLVLTG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEALYVDMGHFGARPIRYGWFVLVMPCLILNYFGQGAMLLTNPAGAENPFYLMVPEPLLI
CHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCHHHH
PMVVLATCATVIASQAVISGAFSLTSQAIQLGFVPRMRVRYTSAAEIGQIYLPVINWILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHHHHH
VLVVAVVISFKKSENLAAAYGIAVTTTMVITTFLAAVVMRNVWKWNPALVTLLGLSFLLV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DLAFFAANLLKVAEGGWFPLLLGSTAFFLLMTWYSGRKLLRARSLEDGIPLEPFIAGLLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
HPPHRVEGTAVFLTGNTESVPVSLLHNLKHNRVLHERVVFLSFVTRDIPYVDDEQRLSCK
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DLGGGVFILKSDYGFKETPDVHKVLDLAQRKLGMHFELMETSFFIARESVIPSKLPGMSM
HCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCHHH
WRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI
HHHHHHHHHHHCCCCCCHHEECCHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA