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The map label for this gene is atzB [H]

Identifier: 73540988

GI number: 73540988

Start: 1382185

End: 1383666

Strand: Direct

Name: atzB [H]

Synonym: Reut_A1294

Alternate gene names: 73540988

Gene position: 1382185-1383666 (Clockwise)

Preceding gene: 73540987

Following gene: 73540989

Centisome position: 36.31

GC content: 64.57

Gene sequence:

>1482_bases
TTGTGGACATCGTTGGCGAAATTCTGCGCTTTCGGATTGACGGCGCGAGTCATAGACTCGCCCCATGCCAATCCGCCGAG
AGTTGCCGATATGACCCTGATCGCCCTGAATGCCGATGTGCTCGTCACCATGGACGCGCAACGGCGAGAAATTCCCGATG
GCGCGCTGGTTGCCGAAGGTCCTGCGGTGCAATGGGTCGGGACTACGGCGGATCTGCCGCTCGAGTATCGCCGCAAGATC
GACGACGGTACGGCACAGATCATCGACATGCGCGGCCACGTGGTGACGCCGGGCCTGGTCAATACGCACCATCACATGTA
CCAAAGTCTGACGCGCGCGGTGCCCGCCGCGCAGGATGCCGAGCTGTTTTCGTGGCTGACCAATCTCTACATGCTGTGGT
CGCACCTGACGCCGGAGATGATCCGCATTTCGACCAAGACCGCGATGGCCGAACTGATGCTGTCGGGATGCACGACCACG
AGCGATCATCTGTACCTCTATCCAAACGGCTCGCGCCTTGATGATTCGATCGCCGCGGCGCAGGAAATGGGCATGCGTTT
CCACGCGGCACGCGGCTCGATGAGCGTCGGCCGCAGCAAGGGCGGTCTCCCGCCCGATGTGGTGGTGGAGGAGGAGGCCG
CAATCCTGCGCGACAGCCAGCGACTCGTGGAGCAATACCACGACGGCTCGCGCCACGCGATGCTGCGCATGGTGCTTGCG
CCGTGCTCGCCGTTCTCCGTGTCGCGCGACCTGATGCGCGAATCGGCGGTCATGGCCCGTCACTACGGCGTTTCGCTGCA
TACCCACCTGGCCGAGAACGATAACGACATCGCCTATTCGCGCGAGAAGTTCGGCCTCACGCCCGCGCAGTATGCCGAGG
ACCTCGGCTGGGTCGGACACGATGTCTGGCATGCCCACTGCGTGAAGCTGGATGACGAAGGGATTGCGCTGTTTGCGCGT
ACCGGCACGGGCGTAGCGCATTGCCCATGCTCGAACATGCGGCTGGCATCCGGTATCGCGCCGGTGCGCGCCATGCGCGA
TGCCGGCGTCAAGGTCGGGCTGGGTGTGGATGGCAGCGCCTCGAACGATGGCGCCCACATGCTTGGCGAAGCGCGCCAGG
CACTGCTGTTGCAACGTGTCGGATTTGGCCCGGCCGCGATGAGTGCGCGTGAGGCGCTGGAGATTGCAACGCTCGGTGGT
GCGCGAGTGCTGAACCGTGATGACATTGGCGCGCTGGCGCCGGGCATGGCGGCCGATTTCGTGGCGTTCGATATGTCGGC
CGTGGGCTTTGCCGGCGGCGGACATGACCCCGTCGCGTCGCTGGTGTTTTGCACGCCCGCGAATGTGGCGACCAGCGTGA
TCAATGGCAGGGTCGTCGTTCGTGACGGCGAACTGCTGACGGCTGACCTGCCGGTCGTACTGTCGCAGCACCGACAGCTC
GCGCGCACATTGTTCGAGCGCGCACGCGACGGCGGAGCCTGA

Upstream 100 bases:

>100_bases
ACCGTGCTGAGTCCGGCGGCCGAGTTGATGGCGGCAGATATCGGCGAGCGGTTGGCCGCGCTGTTCGCGCAAGGGCATTG
ATCGCGTAGGTGTCCACTTT

Downstream 100 bases:

>100_bases
GCGTGTCTTGGTGCCTGCTATCTGGCAGGCACTGAATAATCCAATCAGACGCCGGAAAACAAAAAGGGCCAACCTTGCGG
TTGGCCCTTTTTTCGAATTC

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MWTSLAKFCAFGLTARVIDSPHANPPRVADMTLIALNADVLVTMDAQRREIPDGALVAEGPAVQWVGTTADLPLEYRRKI
DDGTAQIIDMRGHVVTPGLVNTHHHMYQSLTRAVPAAQDAELFSWLTNLYMLWSHLTPEMIRISTKTAMAELMLSGCTTT
SDHLYLYPNGSRLDDSIAAAQEMGMRFHAARGSMSVGRSKGGLPPDVVVEEEAAILRDSQRLVEQYHDGSRHAMLRMVLA
PCSPFSVSRDLMRESAVMARHYGVSLHTHLAENDNDIAYSREKFGLTPAQYAEDLGWVGHDVWHAHCVKLDDEGIALFAR
TGTGVAHCPCSNMRLASGIAPVRAMRDAGVKVGLGVDGSASNDGAHMLGEARQALLLQRVGFGPAAMSAREALEIATLGG
ARVLNRDDIGALAPGMAADFVAFDMSAVGFAGGGHDPVASLVFCTPANVATSVINGRVVVRDGELLTADLPVVLSQHRQL
ARTLFERARDGGA

Sequences:

>Translated_493_residues
MWTSLAKFCAFGLTARVIDSPHANPPRVADMTLIALNADVLVTMDAQRREIPDGALVAEGPAVQWVGTTADLPLEYRRKI
DDGTAQIIDMRGHVVTPGLVNTHHHMYQSLTRAVPAAQDAELFSWLTNLYMLWSHLTPEMIRISTKTAMAELMLSGCTTT
SDHLYLYPNGSRLDDSIAAAQEMGMRFHAARGSMSVGRSKGGLPPDVVVEEEAAILRDSQRLVEQYHDGSRHAMLRMVLA
PCSPFSVSRDLMRESAVMARHYGVSLHTHLAENDNDIAYSREKFGLTPAQYAEDLGWVGHDVWHAHCVKLDDEGIALFAR
TGTGVAHCPCSNMRLASGIAPVRAMRDAGVKVGLGVDGSASNDGAHMLGEARQALLLQRVGFGPAAMSAREALEIATLGG
ARVLNRDDIGALAPGMAADFVAFDMSAVGFAGGGHDPVASLVFCTPANVATSVINGRVVVRDGELLTADLPVVLSQHRQL
ARTLFERARDGGA
>Mature_493_residues
MWTSLAKFCAFGLTARVIDSPHANPPRVADMTLIALNADVLVTMDAQRREIPDGALVAEGPAVQWVGTTADLPLEYRRKI
DDGTAQIIDMRGHVVTPGLVNTHHHMYQSLTRAVPAAQDAELFSWLTNLYMLWSHLTPEMIRISTKTAMAELMLSGCTTT
SDHLYLYPNGSRLDDSIAAAQEMGMRFHAARGSMSVGRSKGGLPPDVVVEEEAAILRDSQRLVEQYHDGSRHAMLRMVLA
PCSPFSVSRDLMRESAVMARHYGVSLHTHLAENDNDIAYSREKFGLTPAQYAEDLGWVGHDVWHAHCVKLDDEGIALFAR
TGTGVAHCPCSNMRLASGIAPVRAMRDAGVKVGLGVDGSASNDGAHMLGEARQALLLQRVGFGPAAMSAREALEIATLGG
ARVLNRDDIGALAPGMAADFVAFDMSAVGFAGGGHDPVASLVFCTPANVATSVINGRVVVRDGELLTADLPVVLSQHRQL
ARTLFERARDGGA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=335, Percent_Identity=24.1791044776119, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789249, Length=410, Percent_Identity=28.780487804878, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87082177, Length=497, Percent_Identity=23.1388329979879, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540282, Length=367, Percent_Identity=23.9782016348774, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319963, Length=344, Percent_Identity=27.0348837209302, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24643849, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 52990; Mature: 52990

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTSLAKFCAFGLTARVIDSPHANPPRVADMTLIALNADVLVTMDAQRREIPDGALVAEG
CCCHHHHHHHHCCHHEECCCCCCCCCCCCCEEEEEECCCEEEEECHHHHCCCCCCEEECC
PAVQWVGTTADLPLEYRRKIDDGTAQIIDMRGHVVTPGLVNTHHHMYQSLTRAVPAAQDA
CCEEEECCCCCCCHHHHHHCCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHCCCCCHH
ELFSWLTNLYMLWSHLTPEMIRISTKTAMAELMLSGCTTTSDHLYLYPNGSRLDDSIAAA
HHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
QEMGMRFHAARGSMSVGRSKGGLPPDVVVEEEAAILRDSQRLVEQYHDGSRHAMLRMVLA
HHHCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
PCSPFSVSRDLMRESAVMARHYGVSLHTHLAENDNDIAYSREKFGLTPAQYAEDLGWVGH
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECHHHHCCCHHHHHHHHCCCCH
DVWHAHCVKLDDEGIALFARTGTGVAHCPCSNMRLASGIAPVRAMRDAGVKVGLGVDGSA
HHHEEEEEEECCCCEEEEEECCCCEEECCCCCCCHHCCCHHHHHHHHCCCEEEECCCCCC
SNDGAHMLGEARQALLLQRVGFGPAAMSAREALEIATLGGARVLNRDDIGALAPGMAADF
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEEECCCCCCCCCCCHHHHH
VAFDMSAVGFAGGGHDPVASLVFCTPANVATSVINGRVVVRDGELLTADLPVVLSQHRQL
HHHHHHHHCCCCCCCCCHHHEEEECCHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHHH
ARTLFERARDGGA
HHHHHHHHHCCCC
>Mature Secondary Structure
MWTSLAKFCAFGLTARVIDSPHANPPRVADMTLIALNADVLVTMDAQRREIPDGALVAEG
CCCHHHHHHHHCCHHEECCCCCCCCCCCCCEEEEEECCCEEEEECHHHHCCCCCCEEECC
PAVQWVGTTADLPLEYRRKIDDGTAQIIDMRGHVVTPGLVNTHHHMYQSLTRAVPAAQDA
CCEEEECCCCCCCHHHHHHCCCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHCCCCCHH
ELFSWLTNLYMLWSHLTPEMIRISTKTAMAELMLSGCTTTSDHLYLYPNGSRLDDSIAAA
HHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
QEMGMRFHAARGSMSVGRSKGGLPPDVVVEEEAAILRDSQRLVEQYHDGSRHAMLRMVLA
HHHCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
PCSPFSVSRDLMRESAVMARHYGVSLHTHLAENDNDIAYSREKFGLTPAQYAEDLGWVGH
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECHHHHCCCHHHHHHHHCCCCH
DVWHAHCVKLDDEGIALFARTGTGVAHCPCSNMRLASGIAPVRAMRDAGVKVGLGVDGSA
HHHEEEEEEECCCCEEEEEECCCCEEECCCCCCCHHCCCHHHHHHHHCCCEEEECCCCCC
SNDGAHMLGEARQALLLQRVGFGPAAMSAREALEIATLGGARVLNRDDIGALAPGMAADF
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEEECCCCCCCCCCCHHHHH
VAFDMSAVGFAGGGHDPVASLVFCTPANVATSVINGRVVVRDGELLTADLPVVLSQHRQL
HHHHHHHHCCCCCCCCCHHHEEEECCHHHHHHHHCCEEEEECCCEEEECHHHHHHHHHHH
ARTLFERARDGGA
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]