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The map label for this gene is pgm [H]

Identifier: 73540449

GI number: 73540449

Start: 805773

End: 807158

Strand: Direct

Name: pgm [H]

Synonym: Reut_A0745

Alternate gene names: 73540449

Gene position: 805773-807158 (Clockwise)

Preceding gene: 73540440

Following gene: 73540450

Centisome position: 21.17

GC content: 64.43

Gene sequence:

>1386_bases
ATGCAAATCGATCCCAGCATCTTCAAAGCCTACGACATCCGCGGCATCGTCGGTAAGACGCTGACCCGCGATGTGGCCCG
CCTGATCGGCCTGTCCTTCGGCTCCGCGGCGGCGGAAGCTGGCGAGAAGGCCGTAGTAGTCGGCCGCGACGGCCGTCTGT
CGGGGCCCGACCTCATTGGCGGCCTGGTCGATGGCCTGCGCGCCACGGGCATGGACGTGATCGATCTCGGCATGGTCGCC
ACGCCGATGGTCTATTTCGGCACGAACATCGAACTGGATGGCGTAAAGGCCACTTCCGGGATCATGGTGACCGGCAGTCA
CAATCCGCCCGACTACAACGGCTTCAAGATGGTGCTGGCCGGCAAGGCGATCTACGGCGAGCAGATTCAGGGTCTGCGCC
AGCGCATCGAGGCGGGCAACTTCGCCAACGGTGCAGGTGCCTACCGCCAATGCGATGTGCGCCAGCAGTACCTTGATCGC
ATCACGAGCGACGTGAAGCTGGCCCGCCCGATGAAGATCGCGCTCGACGCCGGCAACGGCGTGGCTGGCGCCTTCGTCGG
TGACCTGTTCCGCGGCCTGGGCTGCGAGGTGACCGAGCTGTTCTGCGACGTCGACGGCAACTTCCCGAACCATCACCCCG
ATCCTGCCCACGTGGAAAACCTGCAGGACCTGATGAAGTGCCTGCACGAGACCGATTGCGAGCTGGGCCTGGCCTTCGAC
GGCGATGGCGACCGCTTGGGCGTGGTGACGAAGGACGGCCAGGTCATTTTCCCGGACCGCCAGCTGATGCTGTTCGCCGA
GGAGATCCTCGCCCGCAACCCGGGCGCCCAGGTCATCTACGACGTCAAGTGCACCGGCAAGCTGGCACCGTGGATCCGCG
CGCACGGCGGCGAGCCGCTGATGTGGAAGACCGGCCATTCGCTGGTCAAGGCAAAGCTCAAGGAAACCGGCGCGCCGATC
GCCGGCGAGATGAGCGGCCACGTGTTCTTCAAGGACCGCTGGTACGGCTTTGACGATGGCCTGTACACCGGCGCGCGCCT
GCTCGAGATCCTGTCACGCCATACCGATCCGAGCGCCGTACTGAACGCGCTGCCGAACGCCAACAACACGCCGGAACTGC
AACTCAAGTGCGTGGAAGGCGAGCCGTTCACGCTGCTGGACAAGATCAAGGCCAACGCCAGGTTCGAGGGCGCGCGCGAG
GTTATCACCATCGATGGCGTGCGCGTGGAGTATCCCGATGGCTTTGGTCTGGCACGCCCGTCCAACACCACGCCCGTGGT
GGTGATGCGTTTCGAGGCTGACAACGACGCAGCGCTGGCCCGTATCCAGGCTGAATTCAAGCGTGTGATCCTGGCCGAAA
AGCCTGATGCCAAGCTCCCGTTCTGA

Upstream 100 bases:

>100_bases
GGCCATCTCCGCGATCCGGCAAAATAACGCCTTTGGCGCAACGGGCGTCCCGCTGCCGGGACAGCATCTGCCAGCAGAAT
CTAATCACTGGAACCCCCCT

Downstream 100 bases:

>100_bases
GCAGATGCGTGAGGCGATGGCCGCTCCGGCGGCGCCGCAGGCCGTGACGCAGGCGGTGCCGTTCGTGTTGCCAGCGAATC
CGCGCATCCTCGTGGTCAAG

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQIDPSIFKAYDIRGIVGKTLTRDVARLIGLSFGSAAAEAGEKAVVVGRDGRLSGPDLIGGLVDGLRATGMDVIDLGMVA
TPMVYFGTNIELDGVKATSGIMVTGSHNPPDYNGFKMVLAGKAIYGEQIQGLRQRIEAGNFANGAGAYRQCDVRQQYLDR
ITSDVKLARPMKIALDAGNGVAGAFVGDLFRGLGCEVTELFCDVDGNFPNHHPDPAHVENLQDLMKCLHETDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILARNPGAQVIYDVKCTGKLAPWIRAHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHTDPSAVLNALPNANNTPELQLKCVEGEPFTLLDKIKANARFEGARE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF

Sequences:

>Translated_461_residues
MQIDPSIFKAYDIRGIVGKTLTRDVARLIGLSFGSAAAEAGEKAVVVGRDGRLSGPDLIGGLVDGLRATGMDVIDLGMVA
TPMVYFGTNIELDGVKATSGIMVTGSHNPPDYNGFKMVLAGKAIYGEQIQGLRQRIEAGNFANGAGAYRQCDVRQQYLDR
ITSDVKLARPMKIALDAGNGVAGAFVGDLFRGLGCEVTELFCDVDGNFPNHHPDPAHVENLQDLMKCLHETDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILARNPGAQVIYDVKCTGKLAPWIRAHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHTDPSAVLNALPNANNTPELQLKCVEGEPFTLLDKIKANARFEGARE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
>Mature_461_residues
MQIDPSIFKAYDIRGIVGKTLTRDVARLIGLSFGSAAAEAGEKAVVVGRDGRLSGPDLIGGLVDGLRATGMDVIDLGMVA
TPMVYFGTNIELDGVKATSGIMVTGSHNPPDYNGFKMVLAGKAIYGEQIQGLRQRIEAGNFANGAGAYRQCDVRQQYLDR
ITSDVKLARPMKIALDAGNGVAGAFVGDLFRGLGCEVTELFCDVDGNFPNHHPDPAHVENLQDLMKCLHETDCELGLAFD
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILARNPGAQVIYDVKCTGKLAPWIRAHGGEPLMWKTGHSLVKAKLKETGAPI
AGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHTDPSAVLNALPNANNTPELQLKCVEGEPFTLLDKIKANARFEGARE
VITIDGVRVEYPDGFGLARPSNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=466, Percent_Identity=34.1201716738197, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789566, Length=459, Percent_Identity=26.5795206971678, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49888; Mature: 49888

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDPSIFKAYDIRGIVGKTLTRDVARLIGLSFGSAAAEAGEKAVVVGRDGRLSGPDLIG
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCHHHHH
GLVDGLRATGMDVIDLGMVATPMVYFGTNIELDGVKATSGIMVTGSHNPPDYNGFKMVLA
HHHHHHHHCCCCHHHHHHHHCCCEEECCCEEECCEEECCCEEEECCCCCCCCCCEEEEEE
GKAIYGEQIQGLRQRIEAGNFANGAGAYRQCDVRQQYLDRITSDVKLARPMKIALDAGNG
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHECCCCEEEEEECCCC
VAGAFVGDLFRGLGCEVTELFCDVDGNFPNHHPDPAHVENLQDLMKCLHETDCELGLAFD
CHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILARNPGAQVIYDVKCTGKLAPWIRAHGGEPL
CCCCEEEEEECCCEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCE
MWKTGHSLVKAKLKETGAPIAGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHTDPSAV
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHH
LNALPNANNTPELQLKCVEGEPFTLLDKIKANARFEGAREVITIDGVRVEYPDGFGLARP
HHHCCCCCCCCCEEEEEECCCCEEHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
SNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
CCCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure
MQIDPSIFKAYDIRGIVGKTLTRDVARLIGLSFGSAAAEAGEKAVVVGRDGRLSGPDLIG
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCCCCHHHHH
GLVDGLRATGMDVIDLGMVATPMVYFGTNIELDGVKATSGIMVTGSHNPPDYNGFKMVLA
HHHHHHHHCCCCHHHHHHHHCCCEEECCCEEECCEEECCCEEEECCCCCCCCCCEEEEEE
GKAIYGEQIQGLRQRIEAGNFANGAGAYRQCDVRQQYLDRITSDVKLARPMKIALDAGNG
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHECCCCEEEEEECCCC
VAGAFVGDLFRGLGCEVTELFCDVDGNFPNHHPDPAHVENLQDLMKCLHETDCELGLAFD
CHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
GDGDRLGVVTKDGQVIFPDRQLMLFAEEILARNPGAQVIYDVKCTGKLAPWIRAHGGEPL
CCCCEEEEEECCCEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCE
MWKTGHSLVKAKLKETGAPIAGEMSGHVFFKDRWYGFDDGLYTGARLLEILSRHTDPSAV
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHH
LNALPNANNTPELQLKCVEGEPFTLLDKIKANARFEGAREVITIDGVRVEYPDGFGLARP
HHHCCCCCCCCCEEEEEECCCCEEHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
SNTTPVVVMRFEADNDAALARIQAEFKRVILAEKPDAKLPF
CCCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]