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The map label for this gene is rfaC [H]

Identifier: 73540450

GI number: 73540450

Start: 807163

End: 808236

Strand: Direct

Name: rfaC [H]

Synonym: Reut_A0746

Alternate gene names: 73540450

Gene position: 807163-808236 (Clockwise)

Preceding gene: 73540449

Following gene: 73540451

Centisome position: 21.2

GC content: 67.97

Gene sequence:

>1074_bases
ATGCGTGAGGCGATGGCCGCTCCGGCGGCGCCGCAGGCCGTGACGCAGGCGGTGCCGTTCGTGTTGCCAGCGAATCCGCG
CATCCTCGTGGTCAAGGTCTCGTCGCTTGGCGATGTTGTCCACAACATGCCGCTGATCCATGATCTGCGCGCAAGATGGC
CCGGCGCGCAGATCGACTGGGTGGTGGAGGAGGGCTATGTCGACCTCGTGCGCCTGCTGCCGGACGTGGCGCGCGTGATT
CCGTTTGCGCTGCGCCGCTGGCGCAAGCGCTTTTGGCAGTCGGCTATCTGGGACGAGATCGGCGGGGTTCGCGATGCGTT
GCGCGCGCAGCGCTATGACGCAGTGATCGAAAGCCAGGGGCTGCTGAAGACCGCCGTGGTGGCGCGCGTCGCCGCGCGGG
CGGCCAATGCGCCGATCATCGGCCTTGGCAACCGAACGCAGGGCTCCGGCTACGAGCCGGTCGCGCGGCTGCTGTACACC
GATCCCGTCCGCGTCCCGCGCCAGGCGCATTCGGTGCGCCGCTCGCGCCTGCTTGGCGCCGCACTGACGGGCACGGCACC
GCCCGAGCCGCCGAAATTCTTCGGCGTATCGGCGCAATCGCTCCATGTCGAGGATCCGATCTGGGCCCAACTACCGGCAC
GCTTTGCGGTGTGCTTCCATGCCACCGCCGGCGCGAAGAAGAAGTGGCCGGTCGCAAACTGGCATGCACTCGGCCAACGA
CTGCAGGCGGATGGCCTCATGATGCTGCTGCCGTGGGGCAATGAGGCGGAGCGCCGTGCGGCGCAGGAGATTGCCGCAGG
CGTGCCCGGCGCGCAGGTCCTCCCGCGCTTCTCTGTCATGCAGGGCTTCGGGCTGATCAACCGCGCAGAGGTCGTGGTGG
GGGTCGATACCGGGCTCGTCCATATCGCCGCGGCATTGTGCCGGCCCACAGTGGAAATTTATACCGCCACCTGGCGCTGG
AAGACCGAAGGCTACTGGTCCGAACGCATCGCCAATGTGGGCGACGACGGCGTCGTGCCCACGGTCGATGAAGTCTGGCA
GGCCACGTGCCGCGTGCGCGGGACAGGAAACTGA

Upstream 100 bases:

>100_bases
TTCGAGGCTGACAACGACGCAGCGCTGGCCCGTATCCAGGCTGAATTCAAGCGTGTGATCCTGGCCGAAAAGCCTGATGC
CAAGCTCCCGTTCTGAGCAG

Downstream 100 bases:

>100_bases
TGCTACGCGTTCTGTACAGCTTGCTTTGGGTCGTCGTCCTGCCGCTGGCGCTGCTGCGGCTAGCATGGCGCGGTCGCAAG
GAGCCGGGATACGTTCAACA

Product: lipopolysaccharide heptosyltransferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MREAMAAPAAPQAVTQAVPFVLPANPRILVVKVSSLGDVVHNMPLIHDLRARWPGAQIDWVVEEGYVDLVRLLPDVARVI
PFALRRWRKRFWQSAIWDEIGGVRDALRAQRYDAVIESQGLLKTAVVARVAARAANAPIIGLGNRTQGSGYEPVARLLYT
DPVRVPRQAHSVRRSRLLGAALTGTAPPEPPKFFGVSAQSLHVEDPIWAQLPARFAVCFHATAGAKKKWPVANWHALGQR
LQADGLMMLLPWGNEAERRAAQEIAAGVPGAQVLPRFSVMQGFGLINRAEVVVGVDTGLVHIAAALCRPTVEIYTATWRW
KTEGYWSERIANVGDDGVVPTVDEVWQATCRVRGTGN

Sequences:

>Translated_357_residues
MREAMAAPAAPQAVTQAVPFVLPANPRILVVKVSSLGDVVHNMPLIHDLRARWPGAQIDWVVEEGYVDLVRLLPDVARVI
PFALRRWRKRFWQSAIWDEIGGVRDALRAQRYDAVIESQGLLKTAVVARVAARAANAPIIGLGNRTQGSGYEPVARLLYT
DPVRVPRQAHSVRRSRLLGAALTGTAPPEPPKFFGVSAQSLHVEDPIWAQLPARFAVCFHATAGAKKKWPVANWHALGQR
LQADGLMMLLPWGNEAERRAAQEIAAGVPGAQVLPRFSVMQGFGLINRAEVVVGVDTGLVHIAAALCRPTVEIYTATWRW
KTEGYWSERIANVGDDGVVPTVDEVWQATCRVRGTGN
>Mature_357_residues
MREAMAAPAAPQAVTQAVPFVLPANPRILVVKVSSLGDVVHNMPLIHDLRARWPGAQIDWVVEEGYVDLVRLLPDVARVI
PFALRRWRKRFWQSAIWDEIGGVRDALRAQRYDAVIESQGLLKTAVVARVAARAANAPIIGLGNRTQGSGYEPVARLLYT
DPVRVPRQAHSVRRSRLLGAALTGTAPPEPPKFFGVSAQSLHVEDPIWAQLPARFAVCFHATAGAKKKWPVANWHALGQR
LQADGLMMLLPWGNEAERRAAQEIAAGVPGAQVLPRFSVMQGFGLINRAEVVVGVDTGLVHIAAALCRPTVEIYTATWRW
KTEGYWSERIANVGDDGVVPTVDEVWQATCRVRGTGN

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=291, Percent_Identity=37.8006872852234, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 39116; Mature: 39116

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREAMAAPAAPQAVTQAVPFVLPANPRILVVKVSSLGDVVHNMPLIHDLRARWPGAQIDW
CCCCCCCCCCHHHHHHHCCEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHHCCCCCCEEE
VVEEGYVDLVRLLPDVARVIPFALRRWRKRFWQSAIWDEIGGVRDALRAQRYDAVIESQG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLKTAVVARVAARAANAPIIGLGNRTQGSGYEPVARLLYTDPVRVPRQAHSVRRSRLLGA
HHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALTGTAPPEPPKFFGVSAQSLHVEDPIWAQLPARFAVCFHATAGAKKKWPVANWHALGQR
HHCCCCCCCCCCEECCCCCEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHH
LQADGLMMLLPWGNEAERRAAQEIAAGVPGAQVLPRFSVMQGFGLINRAEVVVGVDTGLV
HCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECEEEEECCHHHH
HIAAALCRPTVEIYTATWRWKTEGYWSERIANVGDDGVVPTVDEVWQATCRVRGTGN
HHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREAMAAPAAPQAVTQAVPFVLPANPRILVVKVSSLGDVVHNMPLIHDLRARWPGAQIDW
CCCCCCCCCCHHHHHHHCCEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHHCCCCCCEEE
VVEEGYVDLVRLLPDVARVIPFALRRWRKRFWQSAIWDEIGGVRDALRAQRYDAVIESQG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLKTAVVARVAARAANAPIIGLGNRTQGSGYEPVARLLYTDPVRVPRQAHSVRRSRLLGA
HHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALTGTAPPEPPKFFGVSAQSLHVEDPIWAQLPARFAVCFHATAGAKKKWPVANWHALGQR
HHCCCCCCCCCCEECCCCCEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHH
LQADGLMMLLPWGNEAERRAAQEIAAGVPGAQVLPRFSVMQGFGLINRAEVVVGVDTGLV
HCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECEEEEECCHHHH
HIAAALCRPTVEIYTATWRWKTEGYWSERIANVGDDGVVPTVDEVWQATCRVRGTGN
HHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Glycosyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1527014; 11677609; 1657881 [H]