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The map label for this gene is pyrR [H]

Identifier: 73540413

GI number: 73540413

Start: 766854

End: 767381

Strand: Direct

Name: pyrR [H]

Synonym: Reut_A0707

Alternate gene names: 73540413

Gene position: 766854-767381 (Clockwise)

Preceding gene: 73540412

Following gene: 73540414

Centisome position: 20.15

GC content: 66.67

Gene sequence:

>528_bases
ATGACCCGACACACCAATCCCGACGCCGAGGCGCTTTACCGCGCCTTGCTCGACAAGGCTCAGGCGCTGATTCCGCAAGC
CGAGCGTGCGCAGTGGTCCGTGGCCGGCATCCATTCCGGCGGCGCCTGGATTGCGCATAGGCTCGCGGCGGATCTGGGAC
TGCCTGACCACGGTGTCATCAACGTGGCCTTCCACCGTGACGACTATGCCAAAAAAGGCCTGCACAGCCAGGCCCAGCCG
AGCACGCTGCCGTTCGACGTGCAGGACCGCAAGATCCTGCTGATCGACGACGTGCTGGCGACCGGCCGCACCATCCGCGC
GGCGGTCAATGAACTGTTCGACTATGGCCGTCCCGCGCGTGTCGCGCTGGGCGTGCTGGTGGATCGCGGCGGCCGCGAGC
TGCCGATTGCGGCGGACCTGGTCGCGCTGCAGACTGAACTCCCGCGCGAAGCCACGCTCGTACTAGCGCGCCAGGGTGAA
GGCGCCAAGGCGACCTTTGCCTTTACCACCGAATCATCGGCCGGTTGA

Upstream 100 bases:

>100_bases
ATTCCTCGCGTATGGCCGCCATGGGCGGCGCCCGCCGCGGCGAGCTCGATGCCGAGGCCGCACGCATCATCCTGCAACAG
TATTTCGACCAGCTTCCGCT

Downstream 100 bases:

>100_bases
TCCGGCCAATTTTTCGTTCACCGGCTCCGAGACCAGACTAGTCCCCCCGATTTTTGCCCGCGCCTGACCACCCATGACCA
AGACGTTCCGCAACCCGCAG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTRHTNPDAEALYRALLDKAQALIPQAERAQWSVAGIHSGGAWIAHRLAADLGLPDHGVINVAFHRDDYAKKGLHSQAQP
STLPFDVQDRKILLIDDVLATGRTIRAAVNELFDYGRPARVALGVLVDRGGRELPIAADLVALQTELPREATLVLARQGE
GAKATFAFTTESSAG

Sequences:

>Translated_175_residues
MTRHTNPDAEALYRALLDKAQALIPQAERAQWSVAGIHSGGAWIAHRLAADLGLPDHGVINVAFHRDDYAKKGLHSQAQP
STLPFDVQDRKILLIDDVLATGRTIRAAVNELFDYGRPARVALGVLVDRGGRELPIAADLVALQTELPREATLVLARQGE
GAKATFAFTTESSAG
>Mature_174_residues
TRHTNPDAEALYRALLDKAQALIPQAERAQWSVAGIHSGGAWIAHRLAADLGLPDHGVINVAFHRDDYAKKGLHSQAQPS
TLPFDVQDRKILLIDDVLATGRTIRAAVNELFDYGRPARVALGVLVDRGGRELPIAADLVALQTELPREATLVLARQGEG
AKATFAFTTESSAG

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18837; Mature: 18705

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHTNPDAEALYRALLDKAQALIPQAERAQWSVAGIHSGGAWIAHRLAADLGLPDHGVI
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHCEEEEEEECCCHHHHHHHHHHHCCCCCCCEE
NVAFHRDDYAKKGLHSQAQPSTLPFDVQDRKILLIDDVLATGRTIRAAVNELFDYGRPAR
EEEEECCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCCHH
VALGVLVDRGGRELPIAADLVALQTELPREATLVLARQGEGAKATFAFTTESSAG
HHEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TRHTNPDAEALYRALLDKAQALIPQAERAQWSVAGIHSGGAWIAHRLAADLGLPDHGVI
CCCCCCCHHHHHHHHHHHHHHHCCCCHHCEEEEEEECCCHHHHHHHHHHHCCCCCCCEE
NVAFHRDDYAKKGLHSQAQPSTLPFDVQDRKILLIDDVLATGRTIRAAVNELFDYGRPAR
EEEEECCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCCHH
VALGVLVDRGGRELPIAADLVALQTELPREATLVLARQGEGAKATFAFTTESSAG
HHEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]