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The map label for this gene is plsC [C]

Identifier: 73540211

GI number: 73540211

Start: 548606

End: 549355

Strand: Reverse

Name: plsC [C]

Synonym: Reut_A0505

Alternate gene names: 73540211

Gene position: 549355-548606 (Counterclockwise)

Preceding gene: 73540212

Following gene: 73540210

Centisome position: 14.43

GC content: 64.13

Gene sequence:

>750_bases
ATGATCTTTTTGCGTTCCTTTCTGTTCGCGCTGTACCTGCTGGTGCTGACGCCGCCCTATGCGTGCGCCTGCTTTATCGC
ATTTCCGTTCCTGAACGCCGCGCGGCGCTTCGACTTCGTGCGCGGCTGGACCCGTCTCGTGATCGGTGCGGCGCGCGTCC
TGTGCGGCATCCGCTACCAGATGGAAGGCCGCGAGCATCTCGACGAGATGCTCGACAAGCCCGTGGTCCTGCTCTCCAAG
CACCAGTCCGCCTGGGAAACCGTGGCCTATGTCGCGCTGATGCCCAAGCCGCTGTGCTATGTCTTCAAGCGTGAGCTGCT
GCTGGTGCCGTTCTTCGGCTGGGCGCTCGGCATGCTGAAGATGGTTCACATCAACCGCAAGGAAGGCACCAAGGCGTTCT
CCTCCGCCGCACGGCAGGGCCGTGAGCGCCTCGCCGAAGGCGCCTGGATCATCATGTTCCCCGAGGGCACGCGTACGCCG
TCCGGCCTGGAAAATCCGCGCTACAAGAGTGGCGGTGCCCGCCTTGCCGTGGAAACCGGCGCGTGGGTAATCCCGATGGC
CGTCAATTCGGGCCGCGTATGGCCGCGCAACTCCTTCCTGAAGTACCCGGGCATGATCACGATCTCGATCGGCCCGTCGA
TCCCATCGGCCAACAAGACTGCCGACCAGCTCAACCAGGAAGTTCGCGACTGGATCGAGCGCGACATGCGCCGCATCGAC
GCGCAGAGCTACCGGAACGCGGCCGCATGA

Upstream 100 bases:

>100_bases
GCGCGCGTTCGCACGCTGGCTGTCCGGCGGCGATGGCCAGCCCCGCACAAGTTCGTCCTGATTCCCGCTGCTTCGCCAGT
CATCTCTCAAGCGCCCCCCG

Downstream 100 bases:

>100_bases
GCTTGCTGCGCCCTGCCCCCGACACCCCCGGCGCACAGCTGGAACTGCCGCTGGCCGACAGCGGGCAGGGGATCGTCGCC
GGGCTGGCGCCACAGGTTCC

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Domain Protein; Acyltransferase Family Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Phosphoserine Phosphatase; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; XanthomoNADin Biosynthesis Acyltransferase Protein; Phospholipid And Glycerol Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIFLRSFLFALYLLVLTPPYACACFIAFPFLNAARRFDFVRGWTRLVIGAARVLCGIRYQMEGREHLDEMLDKPVVLLSK
HQSAWETVAYVALMPKPLCYVFKRELLLVPFFGWALGMLKMVHINRKEGTKAFSSAARQGRERLAEGAWIIMFPEGTRTP
SGLENPRYKSGGARLAVETGAWVIPMAVNSGRVWPRNSFLKYPGMITISIGPSIPSANKTADQLNQEVRDWIERDMRRID
AQSYRNAAA

Sequences:

>Translated_249_residues
MIFLRSFLFALYLLVLTPPYACACFIAFPFLNAARRFDFVRGWTRLVIGAARVLCGIRYQMEGREHLDEMLDKPVVLLSK
HQSAWETVAYVALMPKPLCYVFKRELLLVPFFGWALGMLKMVHINRKEGTKAFSSAARQGRERLAEGAWIIMFPEGTRTP
SGLENPRYKSGGARLAVETGAWVIPMAVNSGRVWPRNSFLKYPGMITISIGPSIPSANKTADQLNQEVRDWIERDMRRID
AQSYRNAAA
>Mature_249_residues
MIFLRSFLFALYLLVLTPPYACACFIAFPFLNAARRFDFVRGWTRLVIGAARVLCGIRYQMEGREHLDEMLDKPVVLLSK
HQSAWETVAYVALMPKPLCYVFKRELLLVPFFGWALGMLKMVHINRKEGTKAFSSAARQGRERLAEGAWIIMFPEGTRTP
SGLENPRYKSGGARLAVETGAWVIPMAVNSGRVWPRNSFLKYPGMITISIGPSIPSANKTADQLNQEVRDWIERDMRRID
AQSYRNAAA

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5453718, Length=181, Percent_Identity=26.5193370165746, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15100175, Length=181, Percent_Identity=26.5193370165746, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 28251; Mature: 28251

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLRSFLFALYLLVLTPPYACACFIAFPFLNAARRFDFVRGWTRLVIGAARVLCGIRYQ
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEGREHLDEMLDKPVVLLSKHQSAWETVAYVALMPKPLCYVFKRELLLVPFFGWALGMLK
CCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MVHINRKEGTKAFSSAARQGRERLAEGAWIIMFPEGTRTPSGLENPRYKSGGARLAVETG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
AWVIPMAVNSGRVWPRNSFLKYPGMITISIGPSIPSANKTADQLNQEVRDWIERDMRRID
CEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AQSYRNAAA
HHHHHCCCC
>Mature Secondary Structure
MIFLRSFLFALYLLVLTPPYACACFIAFPFLNAARRFDFVRGWTRLVIGAARVLCGIRYQ
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEGREHLDEMLDKPVVLLSKHQSAWETVAYVALMPKPLCYVFKRELLLVPFFGWALGMLK
CCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MVHINRKEGTKAFSSAARQGRERLAEGAWIIMFPEGTRTPSGLENPRYKSGGARLAVETG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECC
AWVIPMAVNSGRVWPRNSFLKYPGMITISIGPSIPSANKTADQLNQEVRDWIERDMRRID
CEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AQSYRNAAA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA