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The map label for this gene is gmhB [H]

Identifier: 73540212

GI number: 73540212

Start: 549395

End: 549973

Strand: Reverse

Name: gmhB [H]

Synonym: Reut_A0506

Alternate gene names: 73540212

Gene position: 549973-549395 (Counterclockwise)

Preceding gene: 73540213

Following gene: 73540211

Centisome position: 14.45

GC content: 66.84

Gene sequence:

>579_bases
ATGCCACAGACACCGCCCAAATTCGTCGTGCTTGATCGCGACGGGGTCATCAACCTTGACAGCGACCAGTTCGTCAAATC
GCCCGACGAATGGGTGCCGATCGAAGGCAGCCTCGAAGCCATCGCCGCGATGAACCAGGCGGGCTACCGCGTGGTGGTCG
CCAGCAACCAGTCGGGCATCGGCCGCGGCCTGTTCGAGATGAGCGCGCTCAACGCCATGCACGAGAAGATGTACAAGGCG
CTGGCCCATCTCGGCGGGCGTGTGGACGCGGTCTTCTTCTGCCCGCATACCGCGGCCGACAGTTGCGATTGCCGCAAGCC
CAAACCCGGCCTGCTCGACCAGATCAGCGAACGGTTCGGCATCGAACTCAAGGGCGTGCCGATCGTCGGCGACTCGCTGC
GCGACCTGGAGGCCGGTGTGGCGGTCGGCTGCACGCCGCACCTGGTGCTCACCGGCAAGGGCCAGAAGACGCTGGACAAG
GGCGGCCTGCCCCCGGGCACACGCGTCCATGACGACCTGCGCGCGTTCGCACGCTGGCTGTCCGGCGGCGATGGCCAGCC
CCGCACAAGTTCGTCCTGA

Upstream 100 bases:

>100_bases
GGCGCTGCTGGCCTCGCTGCACGCGCTGGCCAACCGCGTGGCGGACATCTCGAAGCTGGCGGCCTGATCGCCACGCCACC
ACGCCAACCGGGAGCCAGAC

Downstream 100 bases:

>100_bases
TTCCCGCTGCTTCGCCAGTCATCTCTCAAGCGCCCCCCGATGATCTTTTTGCGTTCCTTTCTGTTCGCGCTGTACCTGCT
GGTGCTGACGCCGCCCTATG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPQTPPKFVVLDRDGVINLDSDQFVKSPDEWVPIEGSLEAIAAMNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKA
LAHLGGRVDAVFFCPHTAADSCDCRKPKPGLLDQISERFGIELKGVPIVGDSLRDLEAGVAVGCTPHLVLTGKGQKTLDK
GGLPPGTRVHDDLRAFARWLSGGDGQPRTSSS

Sequences:

>Translated_192_residues
MPQTPPKFVVLDRDGVINLDSDQFVKSPDEWVPIEGSLEAIAAMNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKA
LAHLGGRVDAVFFCPHTAADSCDCRKPKPGLLDQISERFGIELKGVPIVGDSLRDLEAGVAVGCTPHLVLTGKGQKTLDK
GGLPPGTRVHDDLRAFARWLSGGDGQPRTSSS
>Mature_191_residues
PQTPPKFVVLDRDGVINLDSDQFVKSPDEWVPIEGSLEAIAAMNQAGYRVVVASNQSGIGRGLFEMSALNAMHEKMYKAL
AHLGGRVDAVFFCPHTAADSCDCRKPKPGLLDQISERFGIELKGVPIVGDSLRDLEAGVAVGCTPHLVLTGKGQKTLDKG
GLPPGTRVHDDLRAFARWLSGGDGQPRTSSS

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=37.2549019607843, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20524; Mature: 20392

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTPPKFVVLDRDGVINLDSDQFVKSPDEWVPIEGSLEAIAAMNQAGYRVVVASNQSGI
CCCCCCCEEEECCCCEEECCCCHHHCCCCCEECCCCCHHHHHHHCCCCEEEEEECCCCCC
GRGLFEMSALNAMHEKMYKALAHLGGRVDAVFFCPHTAADSCDCRKPKPGLLDQISERFG
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHC
IELKGVPIVGDSLRDLEAGVAVGCTPHLVLTGKGQKTLDKGGLPPGTRVHDDLRAFARWL
CEECCCEEECCCHHHHHCCEEECCCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHH
SGGDGQPRTSSS
CCCCCCCCCCCC
>Mature Secondary Structure 
PQTPPKFVVLDRDGVINLDSDQFVKSPDEWVPIEGSLEAIAAMNQAGYRVVVASNQSGI
CCCCCCEEEECCCCEEECCCCHHHCCCCCEECCCCCHHHHHHHCCCCEEEEEECCCCCC
GRGLFEMSALNAMHEKMYKALAHLGGRVDAVFFCPHTAADSCDCRKPKPGLLDQISERFG
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHC
IELKGVPIVGDSLRDLEAGVAVGCTPHLVLTGKGQKTLDKGGLPPGTRVHDDLRAFARWL
CEECCCEEECCCHHHHHCCEEECCCCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHH
SGGDGQPRTSSS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]