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The map label for this gene is qseD [H]

Identifier: 73540161

GI number: 73540161

Start: 501028

End: 501975

Strand: Direct

Name: qseD [H]

Synonym: Reut_A0455

Alternate gene names: 73540161

Gene position: 501028-501975 (Clockwise)

Preceding gene: 73540158

Following gene: 73540162

Centisome position: 13.16

GC content: 66.88

Gene sequence:

>948_bases
ATGGAAATCAAATGGCTTGAAGACTTCGTCAGCCTGGCCGAGACGCACAGCTTCTCGCGCTCGGCCGAACTGCGGCATGT
CACGCAACCGGCGTTCTCGCGCCGGATCCAGTCGCTCGAGGCATGGGTCGGCACGGAGCTGATCGATCGCTCCAGCTACC
CGACCAGCCTGACCGCCGCCGGCAAGGTGTTCTATGAGCAGGCCCTGGCCATGCTGGCGCAGGTCAGCGAGACGCGCGCG
CTGATGCGCGGGCAGCGCTCGTCGAACGCGCAGGTGCTGGAATTCGCGGTGCCGCACACGCTGTCGCTGACGTTCTTTCC
GGAATGGCTCAAGACGCTCGAGCGCAAGGTCGGCACGCTACCGTGCCGGCTGCGGGCGCTCAACGTGCACGACGCGGTGC
TGCTGCTGGTCGAGGGCGGCTGCGACCTGGTCATGGTCTACCACCATGCACGCCAGGCGATCCAGCTCGATCCGGCACGC
TACGACATGCTCGTGCTCGGCATCGAGCGGCTGTCGCCGTACAGTGTGCCCGACAGCACGGGCAAGCCGCTGTACCGGCT
GCCCGGCACGGACAAGAAGCCGGTGCCGTTCCTGAGCTACACGCCCAATGCCTTCCTCGGCCGCATGGTGGACATGCTGC
TCGCCGATACCTCGGAAGAACTCAAGCTCGACAAATGCTACGAGACCGATATGGCAGAGGCGCTCAAGGTCATGGCGCTC
TCGGGGCATGGCATGGCCTTTCTGCCCGAGAGCGCGGTGCGCGACGACGTGGCGCAGGGCCGGCTGGTGCGGGCCGAGTC
GGCGCGCGGGCTGCCGCTGTCGATCGACATGGAGATCCGTCTGTACCGCGAGCGGCCCGGCGATAACGGCAATGACCGGC
GGGCGACGGCGGCGCGTCGGAAGCGGCAACTCGTGGATCGGGTGTGGTCGACGCTGACGACGGATTGA

Upstream 100 bases:

>100_bases
GAGGCAGATGAGTAGAATCTCATTCTACAATGTGCCCACCCGCGGAAACAGCCAGCGCGCCCGGTGACGGCACCGTCCGA
GCCGGTGGATAATCCGCGTC

Downstream 100 bases:

>100_bases
CGGAAGCATGCTCCCTCTCCCGCAAGCGGGAGAGGGAGCATGCCCGGGGTCCGCAAGAGACCTTCCTTCATTGACCAGTC
ATCCTCGAACGTTATGCGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEIKWLEDFVSLAETHSFSRSAELRHVTQPAFSRRIQSLEAWVGTELIDRSSYPTSLTAAGKVFYEQALAMLAQVSETRA
LMRGQRSSNAQVLEFAVPHTLSLTFFPEWLKTLERKVGTLPCRLRALNVHDAVLLLVEGGCDLVMVYHHARQAIQLDPAR
YDMLVLGIERLSPYSVPDSTGKPLYRLPGTDKKPVPFLSYTPNAFLGRMVDMLLADTSEELKLDKCYETDMAEALKVMAL
SGHGMAFLPESAVRDDVAQGRLVRAESARGLPLSIDMEIRLYRERPGDNGNDRRATAARRKRQLVDRVWSTLTTD

Sequences:

>Translated_315_residues
MEIKWLEDFVSLAETHSFSRSAELRHVTQPAFSRRIQSLEAWVGTELIDRSSYPTSLTAAGKVFYEQALAMLAQVSETRA
LMRGQRSSNAQVLEFAVPHTLSLTFFPEWLKTLERKVGTLPCRLRALNVHDAVLLLVEGGCDLVMVYHHARQAIQLDPAR
YDMLVLGIERLSPYSVPDSTGKPLYRLPGTDKKPVPFLSYTPNAFLGRMVDMLLADTSEELKLDKCYETDMAEALKVMAL
SGHGMAFLPESAVRDDVAQGRLVRAESARGLPLSIDMEIRLYRERPGDNGNDRRATAARRKRQLVDRVWSTLTTD
>Mature_315_residues
MEIKWLEDFVSLAETHSFSRSAELRHVTQPAFSRRIQSLEAWVGTELIDRSSYPTSLTAAGKVFYEQALAMLAQVSETRA
LMRGQRSSNAQVLEFAVPHTLSLTFFPEWLKTLERKVGTLPCRLRALNVHDAVLLLVEGGCDLVMVYHHARQAIQLDPAR
YDMLVLGIERLSPYSVPDSTGKPLYRLPGTDKKPVPFLSYTPNAFLGRMVDMLLADTSEELKLDKCYETDMAEALKVMAL
SGHGMAFLPESAVRDDVAQGRLVRAESARGLPLSIDMEIRLYRERPGDNGNDRRATAARRKRQLVDRVWSTLTTD

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=263, Percent_Identity=33.4600760456274, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787879, Length=271, Percent_Identity=26.1992619926199, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=79, Percent_Identity=40.5063291139241, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790399, Length=146, Percent_Identity=28.7671232876712, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35453; Mature: 35453

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKWLEDFVSLAETHSFSRSAELRHVTQPAFSRRIQSLEAWVGTELIDRSSYPTSLTAA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GKVFYEQALAMLAQVSETRALMRGQRSSNAQVLEFAVPHTLSLTFFPEWLKTLERKVGTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHCCC
PCRLRALNVHDAVLLLVEGGCDLVMVYHHARQAIQLDPARYDMLVLGIERLSPYSVPDST
CCEEEEECCCCEEEEEEECCCCEEEEEHHHHHHEEECCHHHHHHEEEHHHCCCCCCCCCC
GKPLYRLPGTDKKPVPFLSYTPNAFLGRMVDMLLADTSEELKLDKCYETDMAEALKVMAL
CCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
SGHGMAFLPESAVRDDVAQGRLVRAESARGLPLSIDMEIRLYRERPGDNGNDRRATAARR
CCCCCEECCCHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHH
KRQLVDRVWSTLTTD
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIKWLEDFVSLAETHSFSRSAELRHVTQPAFSRRIQSLEAWVGTELIDRSSYPTSLTAA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
GKVFYEQALAMLAQVSETRALMRGQRSSNAQVLEFAVPHTLSLTFFPEWLKTLERKVGTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHCCC
PCRLRALNVHDAVLLLVEGGCDLVMVYHHARQAIQLDPARYDMLVLGIERLSPYSVPDST
CCEEEEECCCCEEEEEEECCCCEEEEEHHHHHHEEECCHHHHHHEEEHHHCCCCCCCCCC
GKPLYRLPGTDKKPVPFLSYTPNAFLGRMVDMLLADTSEELKLDKCYETDMAEALKVMAL
CCCEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
SGHGMAFLPESAVRDDVAQGRLVRAESARGLPLSIDMEIRLYRERPGDNGNDRRATAARR
CCCCCEECCCHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHH
KRQLVDRVWSTLTTD
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]