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The map label for this gene is yodT [H]

Identifier: 73540104

GI number: 73540104

Start: 434228

End: 435553

Strand: Direct

Name: yodT [H]

Synonym: Reut_A0398

Alternate gene names: 73540104

Gene position: 434228-435553 (Clockwise)

Preceding gene: 73540102

Following gene: 73540105

Centisome position: 11.41

GC content: 67.27

Gene sequence:

>1326_bases
ATGACCCATGTCTTTCATCGCAACCCGCGCCAAACCTTGCCCGTCGCGGTCGCCGGCAGCGGCGTCGAACTGGTCGACAG
CGAGGGGCGCCGCTACCTCGACGCTTCGGGCGGCGCGGCGGTGTCGTCGCTGGGCCATGGCCATCCGCGCGTGATCGCGG
CGATCAAGGCGCAGCTCGACACCATCGCGTATGCGCATACCTCGTTCTTCACCACCGAGGTCTCCGAAACGCTCGCGCAA
ACGCTGGCGCAGGCCGCGCCCGGCGATCTGGAACATGTCTACTTCGTCTCGGGCGGCTCCGAGGCGGTCGAGGCCGCGCT
CAAGCTCGCGCGCCAGTATTTCGTCGAGCTGGGGCAGGGCAGCCGCCGCCATTTCATCGCGCGGCGCCAGAGTTATCACG
GCAATACACTCGGCGCGCTGGCCATTGGCGGCAACGCATGGCGGCGTGAACCATTCCTGCCGCTGCTAGTGCCCGCGCAC
CATGTGTCGCCGTGCTATGCCTACCGCGACCAGGTGGCCGGCGAGACCGACGCGCAATATGCGCAACGGCTCGCTGACGA
ACTGGAGGCCAAGATCCAGGAACTCGGGGCCGAGAACGTCGCGGCCTTCGTTGCGGAGACCGTGGTCGGCGCCACCGCCG
GCGCCGTGCCGCCGGTGGGCGACTACCTGAAGCGCATTCGCGCTGTCTGCGACAAGTACGGCGTGCTGCTGATCCTGGAC
GAGGTCATGTCCGGCATGGGCCGCACCGGATACCTGTTTGCCTGCGAAGAAGATGGCGTGGTGCCCGATATCGTCACCAT
TGCCAAGGGCCTTGGCGGTGGCTACCAGCCGATCGGCGCGATGATCTCCACGCGCCGGATCTACGACACCATCGTCGCCG
GCAGCGGCTTCTTCCAGCATGGCCACACCTATATCGGCCACGCCACGGCATGCGCCGCCGCGCTGGCCGTGCAGCGCACG
ATCGCCGAAGACAACCTGCTGGCCAATGTGCGACAGCGCGGCGAGCAGTTGCGCGCGCGTTTGCGCGAATCGCTGGGCAA
CCATCCGAACCTTGGCGATATCCGCGGCCGCGGCCTGTTTGTCGGCGTCGAGTTCGTCGCCGACCGCGACAGCAAGGCGA
CGCTGGACCCGAAGCTGAAAACCCATGCCAGGCTGAAGAGCACCGCCATGCAGCACGGCCTGCTGGTCTACCCGATGGGC
GGCACCGTGGACGGCGTGCATGGTGACCACGTGCTGTTCGCCCCGCCATTCATCTGCACGGCGCAGGACATCGACAAGAT
CGTGGAGCGCTTCACGGCTGCGGTCGCCGCGGTGTTGCCCGCCTAG

Upstream 100 bases:

>100_bases
ATCGACCACCGGGACTAGAACGTGTAAGTCCACGGCGCGCCGCCCGGCTCCGCTTCGACGCTTCGAATTCTTGACTCTCC
ATTTCGCAGGACCGATCGCC

Downstream 100 bases:

>100_bases
CGACACAACAGTGCGGCGTGCCGTTATTTGTCACGATTGTGATCATTGGGGTACATGACCGGCCTGTCTTGTAGCCGCAA
CGCCGCACGGTCCACATAGT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTHVFHRNPRQTLPVAVAGSGVELVDSEGRRYLDASGGAAVSSLGHGHPRVIAAIKAQLDTIAYAHTSFFTTEVSETLAQ
TLAQAAPGDLEHVYFVSGGSEAVEAALKLARQYFVELGQGSRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAH
HVSPCYAYRDQVAGETDAQYAQRLADELEAKIQELGAENVAAFVAETVVGATAGAVPPVGDYLKRIRAVCDKYGVLLILD
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGGGYQPIGAMISTRRIYDTIVAGSGFFQHGHTYIGHATACAAALAVQRT
IAEDNLLANVRQRGEQLRARLRESLGNHPNLGDIRGRGLFVGVEFVADRDSKATLDPKLKTHARLKSTAMQHGLLVYPMG
GTVDGVHGDHVLFAPPFICTAQDIDKIVERFTAAVAAVLPA

Sequences:

>Translated_441_residues
MTHVFHRNPRQTLPVAVAGSGVELVDSEGRRYLDASGGAAVSSLGHGHPRVIAAIKAQLDTIAYAHTSFFTTEVSETLAQ
TLAQAAPGDLEHVYFVSGGSEAVEAALKLARQYFVELGQGSRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAH
HVSPCYAYRDQVAGETDAQYAQRLADELEAKIQELGAENVAAFVAETVVGATAGAVPPVGDYLKRIRAVCDKYGVLLILD
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGGGYQPIGAMISTRRIYDTIVAGSGFFQHGHTYIGHATACAAALAVQRT
IAEDNLLANVRQRGEQLRARLRESLGNHPNLGDIRGRGLFVGVEFVADRDSKATLDPKLKTHARLKSTAMQHGLLVYPMG
GTVDGVHGDHVLFAPPFICTAQDIDKIVERFTAAVAAVLPA
>Mature_440_residues
THVFHRNPRQTLPVAVAGSGVELVDSEGRRYLDASGGAAVSSLGHGHPRVIAAIKAQLDTIAYAHTSFFTTEVSETLAQT
LAQAAPGDLEHVYFVSGGSEAVEAALKLARQYFVELGQGSRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHH
VSPCYAYRDQVAGETDAQYAQRLADELEAKIQELGAENVAAFVAETVVGATAGAVPPVGDYLKRIRAVCDKYGVLLILDE
VMSGMGRTGYLFACEEDGVVPDIVTIAKGLGGGYQPIGAMISTRRIYDTIVAGSGFFQHGHTYIGHATACAAALAVQRTI
AEDNLLANVRQRGEQLRARLRESLGNHPNLGDIRGRGLFVGVEFVADRDSKATLDPKLKTHARLKSTAMQHGLLVYPMGG
TVDGVHGDHVLFAPPFICTAQDIDKIVERFTAAVAAVLPA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=429, Percent_Identity=29.8368298368298, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13994255, Length=436, Percent_Identity=29.5871559633028, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=29.1764705882353, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=405, Percent_Identity=29.1358024691358, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=28.4705882352941, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI24119277, Length=424, Percent_Identity=27.3584905660377, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI284507298, Length=342, Percent_Identity=30.1169590643275, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI145693181, Length=422, Percent_Identity=33.8862559241706, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1789016, Length=376, Percent_Identity=34.5744680851064, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1789759, Length=434, Percent_Identity=32.258064516129, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788044, Length=422, Percent_Identity=31.5165876777251, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786991, Length=441, Percent_Identity=30.8390022675737, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=30.5418719211823, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=29.940119760479, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=30.4347826086957, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=30.8219178082192, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=436, Percent_Identity=27.2935779816514, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=241, Percent_Identity=33.195020746888, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=423, Percent_Identity=30.4964539007092, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=438, Percent_Identity=28.0821917808219, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324386, Length=474, Percent_Identity=22.9957805907173, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321456, Length=391, Percent_Identity=24.5524296675192, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356575, Length=432, Percent_Identity=30.787037037037, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21357415, Length=412, Percent_Identity=30.3398058252427, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI28574759, Length=444, Percent_Identity=30.4054054054054, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI161085790, Length=438, Percent_Identity=30.365296803653, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281366494, Length=373, Percent_Identity=24.6648793565684, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667139, Length=373, Percent_Identity=24.6648793565684, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667143, Length=373, Percent_Identity=24.6648793565684, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47153; Mature: 47022

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVFHRNPRQTLPVAVAGSGVELVDSEGRRYLDASGGAAVSSLGHGHPRVIAAIKAQLD
CCCCCCCCCCCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHHHH
TIAYAHTSFFTTEVSETLAQTLAQAAPGDLEHVYFVSGGSEAVEAALKLARQYFVELGQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
SRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCYAYRDQVAGETDAQY
CHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECHHHCCHHHHHHHHHCCCCHHHH
AQRLADELEAKIQELGAENVAAFVAETVVGATAGAVPPVGDYLKRIRAVCDKYGVLLILD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEHH
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGGGYQPIGAMISTRRIYDTIVAGSGFFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHC
GHTYIGHATACAAALAVQRTIAEDNLLANVRQRGEQLRARLRESLGNHPNLGDIRGRGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
VGVEFVADRDSKATLDPKLKTHARLKSTAMQHGLLVYPMGGTVDGVHGDHVLFAPPFICT
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEC
AQDIDKIVERFTAAVAAVLPA
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THVFHRNPRQTLPVAVAGSGVELVDSEGRRYLDASGGAAVSSLGHGHPRVIAAIKAQLD
CCCCCCCCCCCCCEEEECCCCEEECCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHHHH
TIAYAHTSFFTTEVSETLAQTLAQAAPGDLEHVYFVSGGSEAVEAALKLARQYFVELGQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCC
SRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCYAYRDQVAGETDAQY
CHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECHHHCCHHHHHHHHHCCCCHHHH
AQRLADELEAKIQELGAENVAAFVAETVVGATAGAVPPVGDYLKRIRAVCDKYGVLLILD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEHH
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGGGYQPIGAMISTRRIYDTIVAGSGFFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHC
GHTYIGHATACAAALAVQRTIAEDNLLANVRQRGEQLRARLRESLGNHPNLGDIRGRGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
VGVEFVADRDSKATLDPKLKTHARLKSTAMQHGLLVYPMGGTVDGVHGDHVLFAPPFICT
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEC
AQDIDKIVERFTAAVAAVLPA
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]