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The map label for this gene is ydfD [H]

Identifier: 73539957

GI number: 73539957

Start: 279025

End: 280428

Strand: Reverse

Name: ydfD [H]

Synonym: Reut_A0251

Alternate gene names: 73539957

Gene position: 280428-279025 (Counterclockwise)

Preceding gene: 73539963

Following gene: 73539953

Centisome position: 7.37

GC content: 66.1

Gene sequence:

>1404_bases
ATGAAGCTGATCCTCGACGCCGACACCGGCATCCCGCTGACCGACCAGATCATCCAGGGCGTGAAGGCCTGGATCAGCTC
GAGCGAAGCGCGCCCCGGCGCGCGGCTGCCGTCGATCCGGCAACTGGCGGCCGACAACGGCATCAGCCGCTTCCCGGTGA
TCGAAGCTTATGACCGGCTCGTATCGCAGGGATTGCTCGATTCGCGGCAAGGATCGGGGTTCTATGTCGCGGACAGCCCG
CTGGCGAGCCGTTCGGCGCGCGGCTGGTCGGATCCGAGCTTGGCCGAGGACCTGTCCGACCATATCCTCGAACAGTTCAA
TCACCCAAGCAACACGCTCAAGCTCGCAGGCGGCTTTGTGCCGGAGACATGGCGCGATGTAGAGGGCCTGACGCAGGCGA
TCCGCGCGGTCTCGCGCAACGAGATCGACAGCGTGATCCACTACGCGACGCCGATGGGCCACCCCGAACTGCGCCGGCAG
GTACTGCACCGCGTGCGCCAGCTCGGCATCGCAGCGGAACTGCCGCAGGTGCTGATCACGACCGGCGCGAGCCAGGCACT
CGATCTCGTCGTGCGCCATCTGCTCAAGCCCGGCGATACCGTGTTCGTCGAGGACCCGGGCTACTACAACCTCTTTGGCC
TGCTGCGCCTGCACGGCGTGCAACTCGTCGGCGTACCCCAGACCCCATCGGGACCCGATCCGGATGCGACCGAGGCGCTG
TTGCGCCAGCACAAGCCCAAGCTGTTCTTCACCAACAGTGTGTTGCAGAACCCCACGGGTTCGACGCTGGCGCCGCCGGT
CGCGTTCCGGCTGCTGGAACTCGCGCGCCGCCATGGCTTCCGCTTTGTCGAGGACGACATCTTCTCGGACTTCCAGACGC
ACTTCACCGACCGGCTTGCAACGCTGGACCAGCTCGAGCACGTGATCTACATCGGCGGGTTTTCCAAGACCGTGTCGGCG
TCGCTGCGCATCGGCTATGTGGTCGCCGACAAGGCGCTGGTGAAAGACCTCGTGGATGTGAAAGTGCTGACCAGCGTGGC
CGGATCGCACTTCGGTGAAGCCGTCACGGCCGCGCTGCTGGAGCGCGGCGGCTATCGCAAGTATGTGGAACGGCTGCGCC
TGCGCGTGCGGGAGTCATCGGCCAACGCGCTGCGCCAGCTTGCGTCCTGCGGGTGGGAGGTATTCTGCGAGCCAGCCGGC
GGCAATTTCCTGTGGGCCCGCCCGCCGGGCGTCGAGGATTCACGCGAACTGGTCACGCTGGCCGAGACCTTCGGCGTAAC
GATCGCGCCGGGAAACTACTTCCGTCCCGGCGGCGAGACCTCGGCATGGATCCGCGTCAACACCGCCTATGTCAACGAGC
CTCGCGCGGTAGCGTTCATGCGCGAGGCCGCCTCCAAACGCTAG

Upstream 100 bases:

>100_bases
CTTCCATTATTCGGATTGGCGCCTACAATCCCATGTACAGTTGTGAACAGTTTTCGATGAACTGTTCAGCAGTTTTCCCT
GACAGTTCGCCCGCGCCGCC

Downstream 100 bases:

>100_bases
GCCAGCGGCGGGCTCAGCCGCCGTGGTTATGCAGCACGGCGTTGCGCCGCGCGTAGAGGAAATAGATCGCCAGCCCGATC
ACGAGCCAGACCAGGAATGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKLILDADTGIPLTDQIIQGVKAWISSSEARPGARLPSIRQLAADNGISRFPVIEAYDRLVSQGLLDSRQGSGFYVADSP
LASRSARGWSDPSLAEDLSDHILEQFNHPSNTLKLAGGFVPETWRDVEGLTQAIRAVSRNEIDSVIHYATPMGHPELRRQ
VLHRVRQLGIAAELPQVLITTGASQALDLVVRHLLKPGDTVFVEDPGYYNLFGLLRLHGVQLVGVPQTPSGPDPDATEAL
LRQHKPKLFFTNSVLQNPTGSTLAPPVAFRLLELARRHGFRFVEDDIFSDFQTHFTDRLATLDQLEHVIYIGGFSKTVSA
SLRIGYVVADKALVKDLVDVKVLTSVAGSHFGEAVTAALLERGGYRKYVERLRLRVRESSANALRQLASCGWEVFCEPAG
GNFLWARPPGVEDSRELVTLAETFGVTIAPGNYFRPGGETSAWIRVNTAYVNEPRAVAFMREAASKR

Sequences:

>Translated_467_residues
MKLILDADTGIPLTDQIIQGVKAWISSSEARPGARLPSIRQLAADNGISRFPVIEAYDRLVSQGLLDSRQGSGFYVADSP
LASRSARGWSDPSLAEDLSDHILEQFNHPSNTLKLAGGFVPETWRDVEGLTQAIRAVSRNEIDSVIHYATPMGHPELRRQ
VLHRVRQLGIAAELPQVLITTGASQALDLVVRHLLKPGDTVFVEDPGYYNLFGLLRLHGVQLVGVPQTPSGPDPDATEAL
LRQHKPKLFFTNSVLQNPTGSTLAPPVAFRLLELARRHGFRFVEDDIFSDFQTHFTDRLATLDQLEHVIYIGGFSKTVSA
SLRIGYVVADKALVKDLVDVKVLTSVAGSHFGEAVTAALLERGGYRKYVERLRLRVRESSANALRQLASCGWEVFCEPAG
GNFLWARPPGVEDSRELVTLAETFGVTIAPGNYFRPGGETSAWIRVNTAYVNEPRAVAFMREAASKR
>Mature_467_residues
MKLILDADTGIPLTDQIIQGVKAWISSSEARPGARLPSIRQLAADNGISRFPVIEAYDRLVSQGLLDSRQGSGFYVADSP
LASRSARGWSDPSLAEDLSDHILEQFNHPSNTLKLAGGFVPETWRDVEGLTQAIRAVSRNEIDSVIHYATPMGHPELRRQ
VLHRVRQLGIAAELPQVLITTGASQALDLVVRHLLKPGDTVFVEDPGYYNLFGLLRLHGVQLVGVPQTPSGPDPDATEAL
LRQHKPKLFFTNSVLQNPTGSTLAPPVAFRLLELARRHGFRFVEDDIFSDFQTHFTDRLATLDQLEHVIYIGGFSKTVSA
SLRIGYVVADKALVKDLVDVKVLTSVAGSHFGEAVTAALLERGGYRKYVERLRLRVRESSANALRQLASCGWEVFCEPAG
GNFLWARPPGVEDSRELVTLAETFGVTIAPGNYFRPGGETSAWIRVNTAYVNEPRAVAFMREAASKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=321, Percent_Identity=27.1028037383178, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI33469970, Length=321, Percent_Identity=27.1028037383178, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1787710, Length=449, Percent_Identity=29.1759465478842, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790797, Length=440, Percent_Identity=26.3636363636364, Blast_Score=126, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321236, Length=374, Percent_Identity=22.192513368984, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356535, Length=345, Percent_Identity=25.2173913043478, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51324; Mature: 51324

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLILDADTGIPLTDQIIQGVKAWISSSEARPGARLPSIRQLAADNGISRFPVIEAYDRL
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
VSQGLLDSRQGSGFYVADSPLASRSARGWSDPSLAEDLSDHILEQFNHPSNTLKLAGGFV
HHHHHHCCCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
PETWRDVEGLTQAIRAVSRNEIDSVIHYATPMGHPELRRQVLHRVRQLGIAAELPQVLIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCHHHHH
TGASQALDLVVRHLLKPGDTVFVEDPGYYNLFGLLRLHGVQLVGVPQTPSGPDPDATEAL
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
LRQHKPKLFFTNSVLQNPTGSTLAPPVAFRLLELARRHGFRFVEDDIFSDFQTHFTDRLA
HHHCCCCEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHH
TLDQLEHVIYIGGFSKTVSASLRIGYVVADKALVKDLVDVKVLTSVAGSHFGEAVTAALL
HHHHHCCEEEECCCCHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGGYRKYVERLRLRVRESSANALRQLASCGWEVFCEPAGGNFLWARPPGVEDSRELVTL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCCHHHHHH
AETFGVTIAPGNYFRPGGETSAWIRVNTAYVNEPRAVAFMREAASKR
HHHCCCEECCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKLILDADTGIPLTDQIIQGVKAWISSSEARPGARLPSIRQLAADNGISRFPVIEAYDRL
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
VSQGLLDSRQGSGFYVADSPLASRSARGWSDPSLAEDLSDHILEQFNHPSNTLKLAGGFV
HHHHHHCCCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
PETWRDVEGLTQAIRAVSRNEIDSVIHYATPMGHPELRRQVLHRVRQLGIAAELPQVLIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCHHHHH
TGASQALDLVVRHLLKPGDTVFVEDPGYYNLFGLLRLHGVQLVGVPQTPSGPDPDATEAL
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
LRQHKPKLFFTNSVLQNPTGSTLAPPVAFRLLELARRHGFRFVEDDIFSDFQTHFTDRLA
HHHCCCCEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHH
TLDQLEHVIYIGGFSKTVSASLRIGYVVADKALVKDLVDVKVLTSVAGSHFGEAVTAALL
HHHHHCCEEEECCCCHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGGYRKYVERLRLRVRESSANALRQLASCGWEVFCEPAGGNFLWARPPGVEDSRELVTL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCCHHHHHH
AETFGVTIAPGNYFRPGGETSAWIRVNTAYVNEPRAVAFMREAASKR
HHHCCCEECCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]