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The map label for this gene is gdhII [H]

Identifier: 73539931

GI number: 73539931

Start: 250915

End: 251748

Strand: Direct

Name: gdhII [H]

Synonym: Reut_A0225

Alternate gene names: 73539931

Gene position: 250915-251748 (Clockwise)

Preceding gene: 73539928

Following gene: 73539932

Centisome position: 6.59

GC content: 69.78

Gene sequence:

>834_bases
ATGCCCGAATCCAATCCATCTGCCGCCGCTCCATCGCCGGCCCCGCCGCAGGCCACTGCTGCGCGTGGCGTGGCCATCGT
CACCGGCGGCGCGCGCCGGCTTGGCCGCGCCATCGCGCTCGAACTGGCCGCGCAAGGCTGGGATGTGGCCGTGCACTGCC
ACCGCTCGCGCGACGAGGCCGAGGCGCTGGCCGCGCAGATCCGCGCCGGGGGCCGCCGTGCCGCCGTGCTGCAGGCCGAC
CTGGCCGACGAAGCCTCCACGGGGACGCTGATCGCCGCGTGCACGGCTGCACTCGGCGTACCGACCTGCCTCGTCAACAA
TGCCTCGCTGTTCCAGTACGACGTGGCGACGAGCTTCTCGTATGCATCGCTCGACACGCATATGCGCACCAATGTGGCAG
CGCCGTTGCTGCTCGCGCGTGAGATGTACAAGGCACTGAGCGCGGCAGACGCGACCGCGACGGATCCGCGCGGTGTCGTG
ATCAACCTGCTGGACCAGAAGCTCGACAACCTGAATCCGGACTTTCTGTCGTACACGCTGTCCAAGGCCGCGCTGCAGAC
CGCCACGGTGCAGCTTGCGCAGGCCTTCGCGCCGCGCCTGCGCGTGGTCGGCGTCGCGCCCGGCATCACGCTGGTGTCGG
GCGAGCAGTCGGAGCAGAGCTTCCGCCGCGCGCACCGCGTTACGCCGCTGGGCAAGTCGTCCACGCCTGAGGATATCGCC
CAGGCCGTGGCTTACCTTGCCTGCGCGAATGCCGTGACCGGCACCACGCTCTACGTCGACGGCGGCCAGCACCTGATGCC
GCTGTCGCGCGACGTGATGTTCCTGACCGAATGA

Upstream 100 bases:

>100_bases
TGGTTTCGCCGATCAGGGTGGCCAGCGCGTCGGAGGCGGCCAGCGCGTCGGCGGGGGGAAGGGGTAAACTAGCGGCTTTC
TGCATGCCTTGATTGTAGCA

Downstream 100 bases:

>100_bases
TGTAACCACCTGCCGCGCCGGCTGTTTTGGCGCGGCCCCTCCTGAATTCCCTTTCCCCCGCTTGCCATGACCATGCTCGC
CGCCCTGACCCATCCCAGCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MPESNPSAAAPSPAPPQATAARGVAIVTGGARRLGRAIALELAAQGWDVAVHCHRSRDEAEALAAQIRAGGRRAAVLQAD
LADEASTGTLIAACTAALGVPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLAREMYKALSAADATATDPRGVV
INLLDQKLDNLNPDFLSYTLSKAALQTATVQLAQAFAPRLRVVGVAPGITLVSGEQSEQSFRRAHRVTPLGKSSTPEDIA
QAVAYLACANAVTGTTLYVDGGQHLMPLSRDVMFLTE

Sequences:

>Translated_277_residues
MPESNPSAAAPSPAPPQATAARGVAIVTGGARRLGRAIALELAAQGWDVAVHCHRSRDEAEALAAQIRAGGRRAAVLQAD
LADEASTGTLIAACTAALGVPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLAREMYKALSAADATATDPRGVV
INLLDQKLDNLNPDFLSYTLSKAALQTATVQLAQAFAPRLRVVGVAPGITLVSGEQSEQSFRRAHRVTPLGKSSTPEDIA
QAVAYLACANAVTGTTLYVDGGQHLMPLSRDVMFLTE
>Mature_276_residues
PESNPSAAAPSPAPPQATAARGVAIVTGGARRLGRAIALELAAQGWDVAVHCHRSRDEAEALAAQIRAGGRRAAVLQADL
ADEASTGTLIAACTAALGVPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLAREMYKALSAADATATDPRGVVI
NLLDQKLDNLNPDFLSYTLSKAALQTATVQLAQAFAPRLRVVGVAPGITLVSGEQSEQSFRRAHRVTPLGKSSTPEDIAQ
AVAYLACANAVTGTTLYVDGGQHLMPLSRDVMFLTE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=30.241935483871, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=28.2258064516129, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787891, Length=241, Percent_Identity=26.5560165975104, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=28.968253968254, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=29.1497975708502, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=27.8225806451613, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=29.1828793774319, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=26.0223048327138, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.5275590551181, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=28.740157480315, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 28892; Mature: 28761

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESNPSAAAPSPAPPQATAARGVAIVTGGARRLGRAIALELAAQGWDVAVHCHRSRDEA
CCCCCCCCCCCCCCCCCHHHHCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
EALAAQIRAGGRRAAVLQADLADEASTGTLIAACTAALGVPTCLVNNASLFQYDVATSFS
HHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHEECCCHHEEEEHHCCCC
YASLDTHMRTNVAAPLLLAREMYKALSAADATATDPRGVVINLLDQKLDNLNPDFLSYTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SKAALQTATVQLAQAFAPRLRVVGVAPGITLVSGEQSEQSFRRAHRVTPLGKSSTPEDIA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHH
QAVAYLACANAVTGTTLYVDGGQHLMPLSRDVMFLTE
HHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEEC
>Mature Secondary Structure 
PESNPSAAAPSPAPPQATAARGVAIVTGGARRLGRAIALELAAQGWDVAVHCHRSRDEA
CCCCCCCCCCCCCCCCHHHHCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
EALAAQIRAGGRRAAVLQADLADEASTGTLIAACTAALGVPTCLVNNASLFQYDVATSFS
HHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHEECCCHHEEEEHHCCCC
YASLDTHMRTNVAAPLLLAREMYKALSAADATATDPRGVVINLLDQKLDNLNPDFLSYTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SKAALQTATVQLAQAFAPRLRVVGVAPGITLVSGEQSEQSFRRAHRVTPLGKSSTPEDIA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHH
QAVAYLACANAVTGTTLYVDGGQHLMPLSRDVMFLTE
HHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA