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The map label for this gene is birA/coaX [H]

Identifier: 73539808

GI number: 73539808

Start: 128929

End: 129846

Strand: Direct

Name: birA/coaX [H]

Synonym: Reut_A0102

Alternate gene names: 73539808

Gene position: 128929-129846 (Clockwise)

Preceding gene: 73539802

Following gene: 73539809

Centisome position: 3.39

GC content: 72.11

Gene sequence:

>918_bases
ATGTTTATCGGCGTCTACGCCGCGTCCCCACGTCCCGACGTCTTTTCCACGCTTGCCATGACCACCGCCCCCGAATCGCA
ACCCGCCAGCCTGCAATCCTGGCGCATTGACGCCGACGCCCTGCGGGCCGCGTTGCCGCAGGCGCTCCAGGCATGGACGC
TCGACCTGGTCGAAGAGACCGGTTCCACCAACGCCGACCTGACGCAGGCCTGCCGGCAGGCGCCGTGGTCGGACGCCGGC
ACCCTTCGCCTGGCCTATCGCCAGACCGCTGGCCGCGGCCGGCAGGGCCGCCCGTGGCAGGGGCAGGCGGGCCTGACGTT
CTCGGTGGCGCTGCCGCTTGCGCTGTCGCCGTCCCGACTGAGCGGCCTGAGCCTGGGCGTCGGGCTCGCGCTGGCGCAGG
CGCTTGGCGATGTCGAGGCGGCCCTGGGCGCGCGCGTCGGCTTGAAGTGGCCGAACGACCTGCAGATCGACGGGCGCAAG
CTCGCCGGCATCCTGATCGAAGCCGTGCCGGCCGGGCCACAGCGCGTGTGGGCCGTGATCGGCATCGGCCTGAACCTGGT
GCGCGATGCGCAGATGGAGGTCGCGCTCGGACGGGAACTGGCCGGCGTGGCCGAAGCCATGCCGGGTTTCGACGCGCAGC
GCGACGCGACCCGGCTGCTGGCCGCCGTGCTCGCGCGGCTCGGCGCCATGCGCGATGCGTTCGTCGCGCACGGTTTCGCG
CCGATGGCGGCCGAGTGGTCGGCACGCGATGCCTATCGCGACCAGCCCGTGCGGCTTCTGCATGATGGCCAGGTACTGGC
TGAAGGCATGGCCCGGGGCGTCGACGGCGAGGGCCATCTGCTGCTGGAAACGCCTGCCGGTCTCGAACGCATTACCAGTG
GCGAGCTGTCGTTGCGGCCGGCCGGAGGCGCGGCATGA

Upstream 100 bases:

>100_bases
GGGGTGGCGCGAGGAAAGGGCACCGGCGGCTACAATGCGGCCTTGAGCCGGCGCGCGCCTCGCGGCGGTTCCGGGGCCGG
CCTGACCGGCGCAATCCGAC

Downstream 100 bases:

>100_bases
GCGCACCCGTGCTGCTGATCGATATCGGCAATACGCGCCTCAAATGGGCCTGGTGCAATGCCGGCGAGGTCGCCGTGCAG
GAACCGGGCCGGCTGCCGAC

Product: biotin--protein ligase

Products: NA

Alternate protein names: Biotin--[acetyl-CoA-carboxylase] synthetase; Biotin--protein ligase; Type III pantothenate kinase; PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFIGVYAASPRPDVFSTLAMTTAPESQPASLQSWRIDADALRAALPQALQAWTLDLVEETGSTNADLTQACRQAPWSDAG
TLRLAYRQTAGRGRQGRPWQGQAGLTFSVALPLALSPSRLSGLSLGVGLALAQALGDVEAALGARVGLKWPNDLQIDGRK
LAGILIEAVPAGPQRVWAVIGIGLNLVRDAQMEVALGRELAGVAEAMPGFDAQRDATRLLAAVLARLGAMRDAFVAHGFA
PMAAEWSARDAYRDQPVRLLHDGQVLAEGMARGVDGEGHLLLETPAGLERITSGELSLRPAGGAA

Sequences:

>Translated_305_residues
MFIGVYAASPRPDVFSTLAMTTAPESQPASLQSWRIDADALRAALPQALQAWTLDLVEETGSTNADLTQACRQAPWSDAG
TLRLAYRQTAGRGRQGRPWQGQAGLTFSVALPLALSPSRLSGLSLGVGLALAQALGDVEAALGARVGLKWPNDLQIDGRK
LAGILIEAVPAGPQRVWAVIGIGLNLVRDAQMEVALGRELAGVAEAMPGFDAQRDATRLLAAVLARLGAMRDAFVAHGFA
PMAAEWSARDAYRDQPVRLLHDGQVLAEGMARGVDGEGHLLLETPAGLERITSGELSLRPAGGAA
>Mature_305_residues
MFIGVYAASPRPDVFSTLAMTTAPESQPASLQSWRIDADALRAALPQALQAWTLDLVEETGSTNADLTQACRQAPWSDAG
TLRLAYRQTAGRGRQGRPWQGQAGLTFSVALPLALSPSRLSGLSLGVGLALAQALGDVEAALGARVGLKWPNDLQIDGRK
LAGILIEAVPAGPQRVWAVIGIGLNLVRDAQMEVALGRELAGVAEAMPGFDAQRDATRLLAAVLARLGAMRDAFVAHGFA
PMAAEWSARDAYRDQPVRLLHDGQVLAEGMARGVDGEGHLLLETPAGLERITSGELSLRPAGGAA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the type III pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=245, Percent_Identity=35.9183673469388, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143
- InterPro:   IPR008988
- InterPro:   IPR004619 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB; PF03309 Bvg_acc_factor [H]

EC number: =6.3.4.15; =2.7.1.33 [H]

Molecular weight: Translated: 32008; Mature: 32008

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIGVYAASPRPDVFSTLAMTTAPESQPASLQSWRIDADALRAALPQALQAWTLDLVEET
CEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
GSTNADLTQACRQAPWSDAGTLRLAYRQTAGRGRQGRPWQGQAGLTFSVALPLALSPSRL
CCCCCHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECEEECCCHH
SGLSLGVGLALAQALGDVEAALGARVGLKWPNDLQIDGRKLAGILIEAVPAGPQRVWAVI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEHHEEECCCCHHHHHHHH
GIGLNLVRDAQMEVALGRELAGVAEAMPGFDAQRDATRLLAAVLARLGAMRDAFVAHGFA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMAAEWSARDAYRDQPVRLLHDGQVLAEGMARGVDGEGHLLLETPAGLERITSGELSLRP
CHHCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCEEECC
AGGAA
CCCCC
>Mature Secondary Structure
MFIGVYAASPRPDVFSTLAMTTAPESQPASLQSWRIDADALRAALPQALQAWTLDLVEET
CEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
GSTNADLTQACRQAPWSDAGTLRLAYRQTAGRGRQGRPWQGQAGLTFSVALPLALSPSRL
CCCCCHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECEEECCCHH
SGLSLGVGLALAQALGDVEAALGARVGLKWPNDLQIDGRKLAGILIEAVPAGPQRVWAVI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEHHEEECCCCHHHHHHHH
GIGLNLVRDAQMEVALGRELAGVAEAMPGFDAQRDATRLLAAVLARLGAMRDAFVAHGFA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMAAEWSARDAYRDQPVRLLHDGQVLAEGMARGVDGEGHLLLETPAGLERITSGELSLRP
CHHCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCEEECC
AGGAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA