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The map label for this gene is corA [H]

Identifier: 73539771

GI number: 73539771

Start: 79032

End: 80003

Strand: Direct

Name: corA [H]

Synonym: Reut_A0065

Alternate gene names: 73539771

Gene position: 79032-80003 (Clockwise)

Preceding gene: 73539766

Following gene: 73539772

Centisome position: 2.08

GC content: 63.37

Gene sequence:

>972_bases
ATGGGCGCGATCGTCAATAGTGTGGCCTACCGGGAAGGCAAGCGGCTCGGCACGGTCGGCATCAAGGAGATTCCGCAGGC
GCTGAGCGTGCCAGGTACGTTCGTGTGGCTGGGCCTGCATGAGCCGGACCTGGCCCTCCTGCGCCAGGTGCAGCAGTCGT
TCGGGCTGCACGACCTGGCGGTCGAAGACGCACTTGATGCCCACCAGCGGCCGAAGCTCGAGGCCTACGGCGATTCGGTG
TTCATCGTGCTCAACACCGCGCAACTGATCGAGGACGAGGTGGTGGTCGGAGAAACGCATATCTTCGTCGGCCCGAACTA
CGTCGTGTCGGTGCGTCACGGCGCCAGCAGTACCTATGCGCCGGTGCGCGAGCGCTGCGAAAGCGACCCGCAGGGGCTCG
CCAACGGCCCTGGCTATGTGCTCTATGCGCTCATGGATTTCGTGGTCGACCACTACATGCCCATCGTCACGCGCCTGGAA
GATACCTTTGCCGAGTTGGAGCAGGACATCTTCCGCGACGAATTCGACCGCGCAGCGATCGAGCGGCTGTACCAGATCAA
GCGGCAGGTGCTGCGCCTGCGCAATTCGGTGAACCCGGTCGAGGACATGTGCGGCCAGCTTATCCGCCTGCACGAAGACC
TTGTGCCCAAGGAACTGCGCGCCTATTTCCGCGATATCGAGGACCACGCCAGCCGGCTCGTGCGCACACTCGACGTCGTG
CGCGAAATGCTGACCACGGCCGTCCAGGTCAACCTCGCGCTGGTCACCGTGGGGCAGAACGAGGTGGTCAAGCGCCTGGC
GGGCTGGGGTGCGATTCTCGCGATCCCGACCGTGGTGTTCAGCCTCTACGGCATGAATTTCTCGTTTATGCCGGAACTGA
AGTTCCACTATGCGTACCCGGTCGTGATCGGCGTCACGGTTGTCGCTTGCGGGGCGCTATGGCGACGGCTACATCGTGCC
GGATGGATTTGA

Upstream 100 bases:

>100_bases
CTGACGTGTCCAAGTGGTGCCTGCGACAGCGCGGCCGTCCCTTGCGGTCGCGTGCGGCGCTGCCTTGTTACGATTGCTTC
ATCTGCAGAACGGAGCTGTC

Downstream 100 bases:

>100_bases
TGTGCATGATTTATGAATTGAATGGATGTTATTTGATATTCATTGGCATGTGTAATTATTCGCGCGAATAATATTCGGGC
TACCGCCTGCCTTCCGGGCC

Product: Mg2+ transporter protein, CorA-like

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MGAIVNSVAYREGKRLGTVGIKEIPQALSVPGTFVWLGLHEPDLALLRQVQQSFGLHDLAVEDALDAHQRPKLEAYGDSV
FIVLNTAQLIEDEVVVGETHIFVGPNYVVSVRHGASSTYAPVRERCESDPQGLANGPGYVLYALMDFVVDHYMPIVTRLE
DTFAELEQDIFRDEFDRAAIERLYQIKRQVLRLRNSVNPVEDMCGQLIRLHEDLVPKELRAYFRDIEDHASRLVRTLDVV
REMLTTAVQVNLALVTVGQNEVVKRLAGWGAILAIPTVVFSLYGMNFSFMPELKFHYAYPVVIGVTVVACGALWRRLHRA
GWI

Sequences:

>Translated_323_residues
MGAIVNSVAYREGKRLGTVGIKEIPQALSVPGTFVWLGLHEPDLALLRQVQQSFGLHDLAVEDALDAHQRPKLEAYGDSV
FIVLNTAQLIEDEVVVGETHIFVGPNYVVSVRHGASSTYAPVRERCESDPQGLANGPGYVLYALMDFVVDHYMPIVTRLE
DTFAELEQDIFRDEFDRAAIERLYQIKRQVLRLRNSVNPVEDMCGQLIRLHEDLVPKELRAYFRDIEDHASRLVRTLDVV
REMLTTAVQVNLALVTVGQNEVVKRLAGWGAILAIPTVVFSLYGMNFSFMPELKFHYAYPVVIGVTVVACGALWRRLHRA
GWI
>Mature_322_residues
GAIVNSVAYREGKRLGTVGIKEIPQALSVPGTFVWLGLHEPDLALLRQVQQSFGLHDLAVEDALDAHQRPKLEAYGDSVF
IVLNTAQLIEDEVVVGETHIFVGPNYVVSVRHGASSTYAPVRERCESDPQGLANGPGYVLYALMDFVVDHYMPIVTRLED
TFAELEQDIFRDEFDRAAIERLYQIKRQVLRLRNSVNPVEDMCGQLIRLHEDLVPKELRAYFRDIEDHASRLVRTLDVVR
EMLTTAVQVNLALVTVGQNEVVKRLAGWGAILAIPTVVFSLYGMNFSFMPELKFHYAYPVVIGVTVVACGALWRRLHRAG
WI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=345, Percent_Identity=24.3478260869565, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36326; Mature: 36195

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAIVNSVAYREGKRLGTVGIKEIPQALSVPGTFVWLGLHEPDLALLRQVQQSFGLHDLA
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHH
VEDALDAHQRPKLEAYGDSVFIVLNTAQLIEDEVVVGETHIFVGPNYVVSVRHGASSTYA
HHHHHHHHCCCCCHHCCCEEEEEEEHHHHHHCCEEECCEEEEECCCEEEEEECCCCCCCH
PVRERCESDPQGLANGPGYVLYALMDFVVDHYMPIVTRLEDTFAELEQDIFRDEFDRAAI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLYQIKRQVLRLRNSVNPVEDMCGQLIRLHEDLVPKELRAYFRDIEDHASRLVRTLDVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
REMLTTAVQVNLALVTVGQNEVVKRLAGWGAILAIPTVVFSLYGMNFSFMPELKFHYAYP
HHHHHHHHHHEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCHHHHHHH
VVIGVTVVACGALWRRLHRAGWI
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GAIVNSVAYREGKRLGTVGIKEIPQALSVPGTFVWLGLHEPDLALLRQVQQSFGLHDLA
CHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHH
VEDALDAHQRPKLEAYGDSVFIVLNTAQLIEDEVVVGETHIFVGPNYVVSVRHGASSTYA
HHHHHHHHCCCCCHHCCCEEEEEEEHHHHHHCCEEECCEEEEECCCEEEEEECCCCCCCH
PVRERCESDPQGLANGPGYVLYALMDFVVDHYMPIVTRLEDTFAELEQDIFRDEFDRAAI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLYQIKRQVLRLRNSVNPVEDMCGQLIRLHEDLVPKELRAYFRDIEDHASRLVRTLDVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
REMLTTAVQVNLALVTVGQNEVVKRLAGWGAILAIPTVVFSLYGMNFSFMPELKFHYAYP
HHHHHHHHHHEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCHHHHHHH
VVIGVTVVACGALWRRLHRAGWI
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]