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The map label for this gene is nox [C]

Identifier: 71910685

GI number: 71910685

Start: 862962

End: 864032

Strand: Direct

Name: nox [C]

Synonym: M5005_Spy_0872

Alternate gene names: 71910685

Gene position: 862962-864032 (Clockwise)

Preceding gene: 71910684

Following gene: 71910687

Centisome position: 46.94

GC content: 40.52

Gene sequence:

>1071_bases
GTGGAAACTTACGACAAGTTGATTTTTGCAACTGGCTCACAACCTATCTTACCACCGATTAAAGGTGCCGAAATCAAAGA
AGGATCACTTGAATTTGAAGCAACTCTTGAAAATCTTCAATTTGTGAAGTTATACCAAAACTCAGCTGATGTGATTGCAA
AGCTTGAAAACAAAGACATTAAACGTGTAGCCGTAGTTGGTGCTGGTTACATTGGTGTTGAGTTAGCTGAAGCTTTCCAA
CGCAAAGGCAAAGAAGTGGTTCTGATTGATGTCGTGGACACTTGCTTGGCAGGTTATTACGACCGTGATTTGACTGACTT
AATGGCTAAAAACATGGAAGAACATGGTATTCAACTAGCCTTTGGTGAAACAGTTAAAGAAGTAGCTGGTAATGGTAAGG
TTGAAAAGATCATTACTGACAAAAATGAGTACGATGTGGATATGGTTATCCTCGCCGTTGGTTTCCGTCCAAACACAACT
CTTGGAAATGGTAAGATTGATCTTTTCCGTAATGGTGCTTTCCTTGTCAATAAACGCCAAGAAACTTCTATTCCAGGTGT
TTATGCTATCGGTGACTGTGCAACTATCTACGATAATGCTACTCGCGATACAAACTACATTGCTTTAGCTTCAAATGCCG
TCCGTACAGGAATTGTAGCAGCACATAACGCTTGTGGTACAGACCTTGAAGGTATTGGCGTTCAAGGCTCAAACGGTATT
TCCATTTACGGATTGCACATGGTTTCAACTGGTTTGACACTTGAAAAAGCAAAACGTCTTGGTTTTGATGCTGCAGTGAC
TGAGTATACTGATAACCAAAAACCTGAATTTATCGAACACGGTAACTTCCCAGTAACCATTAAGATTGTTTACGATAAAG
ACTCACGTCGTATCTTGGGTGCTCAAATGGCAGCCCGTGAAGATGTGTCAATGGGAATTCACATGTTCTCACTTGCTATC
CAAGAAGGCGTAACCATTGAAAAGTTGGCATTAACTGATATTTTCTTCTTACCACATTTCAACAAACCTTACAACTACAT
CACAATGGCAGCACTTGGTGCCAAAGACTAG

Upstream 100 bases:

>100_bases
ATTAGAGTCTTTAGGGGCTAAAGTTTACATGGAATCACCTGTTCAATCAATCGACTACGATGCCAAAACAGTGACAGCGC
TTGTTGATGGTAAAAACCAC

Downstream 100 bases:

>100_bases
TATCTGATAGGAAAAAGCCAGAGCAGTTCAGCAGCACTGGCTTTTTTGCTTTTTAATTGTTGCAACCTGAAAAGTTCTAA
ACTTATGATTATCCTCTTAT

Product: NADH oxidase H2O-forming

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQ
RKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTT
LGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGI
SIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAI
QEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD

Sequences:

>Translated_356_residues
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQ
RKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTT
LGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGI
SIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAI
QEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD
>Mature_356_residues
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQ
RKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTT
LGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGI
SIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAI
QEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI226437568, Length=232, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI65787454, Length=232, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789065, Length=195, Percent_Identity=31.7948717948718, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789765, Length=246, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32565766, Length=141, Percent_Identity=29.0780141843972, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639257, Length=228, Percent_Identity=26.7543859649123, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281359715, Length=228, Percent_Identity=26.7543859649123, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359713, Length=228, Percent_Identity=26.7543859649123, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639250, Length=228, Percent_Identity=26.7543859649123, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18543267, Length=228, Percent_Identity=26.7543859649123, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639252, Length=228, Percent_Identity=26.7543859649123, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358499, Length=196, Percent_Identity=30.1020408163265, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 38922; Mature: 38922

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
CCCHHCEEEECCCCCCCCCCCCCCCCCCCEEEEEHHCCCEEEEEECCCCCEEEEECCCCC
KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLA
EEEEEEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCCCHHHHHHCCHHHCCEEEE
FGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLVNKRQ
EHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCEEEEECCC
ETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGI
CCCCCCEEEECCCCEECCCCCCCCCEEEEECCCHHHCEEEECCCCCCCCCCCCCCCCCCE
SIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILG
EEEEEEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCEEEEEEEECCCCEEHH
AQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD
HHHHHHHHHHHHHHHEEHHHHCCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
METYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
CCCHHCEEEECCCCCCCCCCCCCCCCCCCEEEEEHHCCCEEEEEECCCCCEEEEECCCCC
KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLA
EEEEEEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCCCHHHHHHCCHHHCCEEEE
FGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLVNKRQ
EHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCEEEEECCC
ETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGI
CCCCCCEEEECCCCEECCCCCCCCCEEEEECCCHHHCEEEECCCCCCCCCCCCCCCCCCE
SIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILG
EEEEEEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCEEEEEEEECCCCEEHH
AQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD
HHHHHHHHHHHHHHHEEHHHHCCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA