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The map label for this gene is opuCB [H]

Identifier: 71910669

GI number: 71910669

Start: 846233

End: 847759

Strand: Direct

Name: opuCB [H]

Synonym: M5005_Spy_0856

Alternate gene names: 71910669

Gene position: 846233-847759 (Clockwise)

Preceding gene: 71910668

Following gene: 71910670

Centisome position: 46.03

GC content: 39.49

Gene sequence:

>1527_bases
ATGCCTAGTTTGTTTGTAACTTTCCAAAACCGTTTTAATGAATGGCTGGCGGCTCTGGGGGAACACCTGCAAATTTCCCT
TTTATCTCTTATGATCGCCTTGCTAATAGGTGTGCCTTTAGCAGCCCTTCTCAGTCGCAGCAAACGTTGGTCAGACATTA
TGTTACAGGTAACAGGTGTTTTTCAAACCATTCCCTCACTGGCTTTGCTTGGTCTTTTCATCCCTTTAATGGGAATTGGA
ACGTTGCCTGCAGTGACAGCTTTAGTTATCTATGCGATTTTTCCGATTTTACAAAACACCATCACAGGATTAAATGGTAT
TGACCCAAGTCTCGTGGAAGCAGGAATAGCTTTTGGGATGACCAAATGGGAGCGATTGAAAACATTTGAGATTCCAATTG
CCATGCCTGTTATTATGTCAGGTGTGCGGACGTCAGCAGTCATGATTATCGGCACAGCTACTTTAGCTTCCTTGATAGGA
GCCGGTGGACTTGGCTCTTTCATCTTATTAGGGATTGATCGTAATAATGCTAACCTGATTCTGATAGGGGCTATTTCTTC
AGCTCTGCTAGCTATTATTTTCAATAGTTTGTTACAGTACCTTGAGAAAGCTTCCTTGCGACGGATTATGATTAGTTTTG
GAATTACCTTACTTGCACTGCTAGCATCGTATACTCCTATGGCGCTTAGTCAGTTTTCAAAAGGAAAAGATACAGTGGTT
ATTGCCGGTAAATTGGGAGCAGAGCCCGATATTCTGATTAATCTCTATAAGGAATTAATTGAAGACCAATCAGATATAAG
TGTTGAGTTGAAATCTAATTTTGGGAAAACTAGCTTCTTATATGAAGCCCTTAAATCTGGAGATATTGATATGTATCCTG
AATTTACAGGAACCATAACATCAAGTCTTTTACGCGACAAACCACCTTTGTCTAATGACCCTAAGCAGGTCTATGAGGAT
GCTAAAAAAGGCATTGCTAAGCAAGATAAACTGACCCTTCTCAAGCCATTTGCTTACCAAAATACGTATGCTGTTGCTAT
GCCAGAAAAATTGGCTAAGGAATATCAGATTGAAACCATTTCTGATTTAAAAGCGCATGCTGATACTTTAAAGGCCGGTT
TTACTTTGGAATTTAAGGACAGAGCAGATGGCTATAAGGGAATGCAATCTCAATATGGATTACAGCTATCTGTGGCGACG
ATGGAGCCAGCTCTTCGTTATCAAGCAATTCAATCAGGAGATATCCAAGTAACAGATGCTTACTCTACGGATGCTGAAAT
TACGAAATACCATTTGAAAGTTTTAAAGGATGATAAACAGTTGTTTCCACCTTATCAGGGAGCTCCTTTGATGAAAACTT
CCTTATTAACAAAACATCCAGAATTAAAAGGCATTCTTAATCAATTAGCGGGAAAAATTACTGAAAAAGAGATGCAGGAC
ATGAACTACGAGGTATCTGTTAAAGGAGCAGATGCTAATAAGGTCGCTCGAGATTATCTGTTGAAAACAGGCTTAATCCA
GAAATAA

Upstream 100 bases:

>100_bases
ATTTTAAATGAGGGAGAAATTGTGCAACTGGATCGCCCAGAAATGATTAAGACCCACCCTGCTAATGCTTTTGTGGTCAA
TTTATTTGGAGGTGATGAGC

Downstream 100 bases:

>100_bases
ACAGAAATGTTGGTCCGTAGGACTGGCATTTTTTCGTCTCTTAAGTTCAAGAAGTAACAATTCATAAACACAAAAACCGA
ACTTTAAAATTAAAAATAGC

Product: glycine betaine transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIG
TLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVV
IAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYED
AKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVAT
MEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQD
MNYEVSVKGADANKVARDYLLKTGLIQK

Sequences:

>Translated_508_residues
MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIG
TLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVV
IAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYED
AKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVAT
MEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQD
MNYEVSVKGADANKVARDYLLKTGLIQK
>Mature_507_residues
PSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGT
LPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIGA
GGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVVI
AGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYEDA
KKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVATM
EPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQDM
NYEVSVKGADANKVARDYLLKTGLIQK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=197, Percent_Identity=37.0558375634518, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788452, Length=280, Percent_Identity=27.8571428571429, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788451, Length=215, Percent_Identity=33.4883720930233, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789033, Length=176, Percent_Identity=35.2272727272727, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55574; Mature: 55443

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
TKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIGAGGLGSFILLGIDRNNANLI
HHHHHHEEEECCHHHHHHHHCCCHHHEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEE
IAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTIT
EEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
SSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETI
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCHHCCCEEEEECCHHHHHHHHHHHH
SDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVATMEPALRYQAIQSGDIQVTDA
HHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEEEHHCHHHHHHHHCCCCEEEEEC
YSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQD
CCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
MNYEVSVKGADANKVARDYLLKTGLIQK
CCEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALLSRSKRWSDIMLQVTGV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTITGLNGIDPSLVEAGIAFGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
TKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIGAGGLGSFILLGIDRNNANLI
HHHHHHEEEECCHHHHHHHHCCCHHHEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLLALLASYTPMALSQFSKGKDTVV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEE
IAGKLGAEPDILINLYKELIEDQSDISVELKSNFGKTSFLYEALKSGDIDMYPEFTGTIT
EEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
SSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLLKPFAYQNTYAVAMPEKLAKEYQIETI
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCHHCCCEEEEECCHHHHHHHHHHHH
SDLKAHADTLKAGFTLEFKDRADGYKGMQSQYGLQLSVATMEPALRYQAIQSGDIQVTDA
HHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCEEEEEHHCHHHHHHHHCCCCEEEEEC
YSTDAEITKYHLKVLKDDKQLFPPYQGAPLMKTSLLTKHPELKGILNQLAGKITEKEMQD
CCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
MNYEVSVKGADANKVARDYLLKTGLIQK
CCEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]