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The map label for this gene is kdtA [H]

Identifier: 71892374

GI number: 71892374

Start: 756944

End: 758227

Strand: Direct

Name: kdtA [H]

Synonym: BPEN_633

Alternate gene names: 71892374

Gene position: 756944-758227 (Clockwise)

Preceding gene: 71892373

Following gene: 71892375

Centisome position: 95.62

GC content: 32.55

Gene sequence:

>1284_bases
ATGTTTATAATATACATTACAATATATAATATTATAATGTATATTGCTCAACCTATAATATGGATACGATTATTATGGCG
CAGCAGACGATCGCCATCGTATCGTAAATGTTGGTTGGAACGCTACGGATTTTATAGAAAATCTATCCAATCTGATGGAA
TCATTTTACATGCTGTGTCCTTAGGAGAAACATTAGCAGCTATCCCCCTGATACGTGCTTTGCAGCAGCGTTACCCAAAA
ATAACAATCACATTAACTGCGATGACTCCCACAGGAATAGAATTGGCGCGCTCTAAATTTAGTCATAATACGCACTGCAG
TTATTTACCTTATGATTTACCTGGTGCTATGAAACGATTTATTAATCAAGTTAAGCCACGATTAGTTATTGCTATGGAAA
CTGAACTATGGCCAAATCTCATAAATATATTATATCAACGCAAGATTCCTTTCATTATTGCTAACGCACGGTTATCATAT
CGCTCTTTTACAGGATATAATAGATTTAGTTATTTTATTTCATTGATTATGAAACGTATTACTTTAATTGCTGCTCAAAA
TAAAGAAGACGCTTCTCGATTTCTTAAATTAGGGTTTAAAAAAAATCAATTATTTATCACAGGTAATTTAAAATATGATA
TTGAAATGAACCAAGATTTATTAAATAAAATTTCATTTTTAAAAAAAAATTGGATTAAAAAACGGCAGGTGTGGATAGCT
AGTAGTACTCATTCAGGAGAAGAGATATTATTATTACAAGCACATAAACATCTCTTGACAAGGTTTCCTAATTTACTAAT
GATTTTGGCTCCACGTCACCCAGAACGTTTTATTAGTGTTAAAAACATTACTGAACAAGCCGGATTGTCTTATATCATGA
GAAGTAATGGGGTTGCTCCATCTAAAGAAACGCAAGTAATTATTAATGATACTATAGGAGAATTAATGTTACTATACGGT
GTTTCAGATATAGCATTTATTGGAGGTAGTTTAGTAAAACATGGAGGACATAATCCGTTGGAGCCAGCTGCACATTCTAT
TCCATTGATCATGGGGCCGTATACTTTTAATTTTAATGATATTTGCATTAAATTATGTAAATCAAATGGGTTAATTACAG
TAACTGATACGGAATCCTTAGTGAAGGCTGTTGCTATGTTGCTGGTAAATCAACAGTGTCGTGTGAACTATGGTTATAGA
GCCATCAAAGTGCTGCAGCATAATCAAGGAGCACTAAAGCAATTATTGGGTTTGTTAGATAGTTATTTATTAGTTCAAAA
ATAA

Upstream 100 bases:

>100_bases
ATTATATAAAAAATAGCGATATTGATATATAGTTTAAATACATATAAAATAATTAAATTAGTAATTATGAATATAATAAC
TGATTACTTTAGGATATGAT

Downstream 100 bases:

>100_bases
CTTTTCATATGATGTTTTGTGATGGTTATAAATTATATATAACAGTTGTTATTAAATATTCATATATTTACAAATGACTT
TTTATCAGATTAACTATAAC

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MFIIYITIYNIIMYIAQPIIWIRLLWRSRRSPSYRKCWLERYGFYRKSIQSDGIILHAVSLGETLAAIPLIRALQQRYPK
ITITLTAMTPTGIELARSKFSHNTHCSYLPYDLPGAMKRFINQVKPRLVIAMETELWPNLINILYQRKIPFIIANARLSY
RSFTGYNRFSYFISLIMKRITLIAAQNKEDASRFLKLGFKKNQLFITGNLKYDIEMNQDLLNKISFLKKNWIKKRQVWIA
SSTHSGEEILLLQAHKHLLTRFPNLLMILAPRHPERFISVKNITEQAGLSYIMRSNGVAPSKETQVIINDTIGELMLLYG
VSDIAFIGGSLVKHGGHNPLEPAAHSIPLIMGPYTFNFNDICIKLCKSNGLITVTDTESLVKAVAMLLVNQQCRVNYGYR
AIKVLQHNQGALKQLLGLLDSYLLVQK

Sequences:

>Translated_427_residues
MFIIYITIYNIIMYIAQPIIWIRLLWRSRRSPSYRKCWLERYGFYRKSIQSDGIILHAVSLGETLAAIPLIRALQQRYPK
ITITLTAMTPTGIELARSKFSHNTHCSYLPYDLPGAMKRFINQVKPRLVIAMETELWPNLINILYQRKIPFIIANARLSY
RSFTGYNRFSYFISLIMKRITLIAAQNKEDASRFLKLGFKKNQLFITGNLKYDIEMNQDLLNKISFLKKNWIKKRQVWIA
SSTHSGEEILLLQAHKHLLTRFPNLLMILAPRHPERFISVKNITEQAGLSYIMRSNGVAPSKETQVIINDTIGELMLLYG
VSDIAFIGGSLVKHGGHNPLEPAAHSIPLIMGPYTFNFNDICIKLCKSNGLITVTDTESLVKAVAMLLVNQQCRVNYGYR
AIKVLQHNQGALKQLLGLLDSYLLVQK
>Mature_427_residues
MFIIYITIYNIIMYIAQPIIWIRLLWRSRRSPSYRKCWLERYGFYRKSIQSDGIILHAVSLGETLAAIPLIRALQQRYPK
ITITLTAMTPTGIELARSKFSHNTHCSYLPYDLPGAMKRFINQVKPRLVIAMETELWPNLINILYQRKIPFIIANARLSY
RSFTGYNRFSYFISLIMKRITLIAAQNKEDASRFLKLGFKKNQLFITGNLKYDIEMNQDLLNKISFLKKNWIKKRQVWIA
SSTHSGEEILLLQAHKHLLTRFPNLLMILAPRHPERFISVKNITEQAGLSYIMRSNGVAPSKETQVIINDTIGELMLLYG
VSDIAFIGGSLVKHGGHNPLEPAAHSIPLIMGPYTFNFNDICIKLCKSNGLITVTDTESLVKAVAMLLVNQQCRVNYGYR
AIKVLQHNQGALKQLLGLLDSYLLVQK

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=416, Percent_Identity=57.6923076923077, Blast_Score=523, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 49022; Mature: 49022

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIIYITIYNIIMYIAQPIIWIRLLWRSRRSPSYRKCWLERYGFYRKSIQSDGIILHAVS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
LGETLAAIPLIRALQQRYPKITITLTAMTPTGIELARSKFSHNTHCSYLPYDLPGAMKRF
HHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHH
INQVKPRLVIAMETELWPNLINILYQRKIPFIIANARLSYRSFTGYNRFSYFISLIMKRI
HHHCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEHHCCCCHHHHHHHHHHHHHH
TLIAAQNKEDASRFLKLGFKKNQLFITGNLKYDIEMNQDLLNKISFLKKNWIKKRQVWIA
HHHHCCCHHHHHHHHHCCCCCCEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHEEEEE
SSTHSGEEILLLQAHKHLLTRFPNLLMILAPRHPERFISVKNITEQAGLSYIMRSNGVAP
ECCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCHHHHEEHHHHHHHHHHHHHHHCCCCCC
SKETQVIINDTIGELMLLYGVSDIAFIGGSLVKHGGHNPLEPAAHSIPLIMGPYTFNFND
CCCCEEEEECHHHHHHHHHCCHHHHHHCCHHHHCCCCCCCCCHHCCCCEEECCEEECHHH
ICIKLCKSNGLITVTDTESLVKAVAMLLVNQQCRVNYGYRAIKVLQHNQGALKQLLGLLD
HHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCHHHHHHHHHHHH
SYLLVQK
HHHHCCC
>Mature Secondary Structure
MFIIYITIYNIIMYIAQPIIWIRLLWRSRRSPSYRKCWLERYGFYRKSIQSDGIILHAVS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
LGETLAAIPLIRALQQRYPKITITLTAMTPTGIELARSKFSHNTHCSYLPYDLPGAMKRF
HHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHH
INQVKPRLVIAMETELWPNLINILYQRKIPFIIANARLSYRSFTGYNRFSYFISLIMKRI
HHHCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEHHCCCCHHHHHHHHHHHHHH
TLIAAQNKEDASRFLKLGFKKNQLFITGNLKYDIEMNQDLLNKISFLKKNWIKKRQVWIA
HHHHCCCHHHHHHHHHCCCCCCEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHEEEEE
SSTHSGEEILLLQAHKHLLTRFPNLLMILAPRHPERFISVKNITEQAGLSYIMRSNGVAP
ECCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCHHHHEEHHHHHHHHHHHHHHHCCCCCC
SKETQVIINDTIGELMLLYGVSDIAFIGGSLVKHGGHNPLEPAAHSIPLIMGPYTFNFND
CCCCEEEEECHHHHHHHHHCCHHHHHHCCHHHHCCCCCCCCCHHCCCCEEECCEEECHHH
ICIKLCKSNGLITVTDTESLVKAVAMLLVNQQCRVNYGYRAIKVLQHNQGALKQLLGLLD
HHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCHHHHHHHHHHHH
SYLLVQK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]