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The map label for this gene is gpsA

Identifier: 71892367

GI number: 71892367

Start: 749172

End: 750206

Strand: Reverse

Name: gpsA

Synonym: BPEN_626

Alternate gene names: 71892367

Gene position: 750206-749172 (Counterclockwise)

Preceding gene: 71892368

Following gene: 71892366

Centisome position: 94.76

GC content: 34.4

Gene sequence:

>1035_bases
GTGTCTATTAAATACCCTAAATATCCTAACATCACTATTATTGGAGCAGGTTCCTATGGAACGGCCATAGCTATTGCGTT
ATCTAGAAATGGTCATTCCGTATTGTTATGGGGACATAATGCAATTCATATTCAAAAACTCCAAATTAATCGATGCAATC
AAGCCTATTTACCCGGTATCGCTTTTCCACCATCATTGTATTTAGAGAAATCGTTGTCTATAGCTTTATCTACTTGCCGA
AATTTATTGATTGCGGTTCCAAGTCGTGTATTTGGTCATGTTTTGATGCGATTAAAACCAAATTTAAAGAGCAATACTCG
TATTATTATAGCATCTAAAGGTTTAGAGCCAAAAACTGGACGTTTATTACAAGATGTGGCGTATGATATTTTAGGAAAAA
ATATTCCTATTGCAATTATATCTGGTCCAACTTTCGCTAGAGAACTCGCTATGGGATTGCCCACGGCAATAACTCTAGCT
TCTAATGATACTATATTAAGTTGTGATCTACAAAATATACTACATTGTAATAAAAATTTCAGAATATACAGCAACACAGA
TACTATTGGTATTCAAATAGCTGGAGTAGTAAAAAACATTATTGCTATCGGAGCAGGTATTTCTGATGGCATAGGGTTTG
GATCCAATGCCCGGACAGCATTAATTACGCGGGGTTTAGTAGAGATGTCTCGCCTAGGTATAGCAATTGGAGCGACACTA
GACACTTTCATGGGATTAGCTGGATTAGGAGATTTGATATTAACTTGCACTGATAATCAATCACGTAATCGTCGCTTTGG
AATATTATTGGGACAGGGTTTCGAGATACATCATGCTCAAAAAAATGTTGGGAAAATAATAGAAGGATTCTATAACATAA
AAGAAGTATATATGTTATCTGTTAAACACAAAGTAGATATGCCCATTACCGAACAAACATATCAAATACTATATCAAAAT
AAAAATGTTCATGATGCAGCTCACTCTTTATTGGAACGTACACAAAAAGAAGAAAAAATTAATGGTTTAAAATAA

Upstream 100 bases:

>100_bases
TCCAATTAATTTCGATATTTTGTTTATTCAGTCCTTACAAAAGAAATATAATGATACACTTAAAATTTAATATTTTAAAA
AATAGTTAGTTTAAATTATT

Downstream 100 bases:

>100_bases
TTAATAATAGATTTCAATTATCATTCATACTACGGCGATTAGGTAAGTGCATGACTTTAAATATATTAGAAATAGTTTGG
AGTAACATTAAAATTGAAGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSIKYPKYPNITIIGAGSYGTAIAIALSRNGHSVLLWGHNAIHIQKLQINRCNQAYLPGIAFPPSLYLEKSLSIALSTCR
NLLIAVPSRVFGHVLMRLKPNLKSNTRIIIASKGLEPKTGRLLQDVAYDILGKNIPIAIISGPTFARELAMGLPTAITLA
SNDTILSCDLQNILHCNKNFRIYSNTDTIGIQIAGVVKNIIAIGAGISDGIGFGSNARTALITRGLVEMSRLGIAIGATL
DTFMGLAGLGDLILTCTDNQSRNRRFGILLGQGFEIHHAQKNVGKIIEGFYNIKEVYMLSVKHKVDMPITEQTYQILYQN
KNVHDAAHSLLERTQKEEKINGLK

Sequences:

>Translated_344_residues
MSIKYPKYPNITIIGAGSYGTAIAIALSRNGHSVLLWGHNAIHIQKLQINRCNQAYLPGIAFPPSLYLEKSLSIALSTCR
NLLIAVPSRVFGHVLMRLKPNLKSNTRIIIASKGLEPKTGRLLQDVAYDILGKNIPIAIISGPTFARELAMGLPTAITLA
SNDTILSCDLQNILHCNKNFRIYSNTDTIGIQIAGVVKNIIAIGAGISDGIGFGSNARTALITRGLVEMSRLGIAIGATL
DTFMGLAGLGDLILTCTDNQSRNRRFGILLGQGFEIHHAQKNVGKIIEGFYNIKEVYMLSVKHKVDMPITEQTYQILYQN
KNVHDAAHSLLERTQKEEKINGLK
>Mature_343_residues
SIKYPKYPNITIIGAGSYGTAIAIALSRNGHSVLLWGHNAIHIQKLQINRCNQAYLPGIAFPPSLYLEKSLSIALSTCRN
LLIAVPSRVFGHVLMRLKPNLKSNTRIIIASKGLEPKTGRLLQDVAYDILGKNIPIAIISGPTFARELAMGLPTAITLAS
NDTILSCDLQNILHCNKNFRIYSNTDTIGIQIAGVVKNIIAIGAGISDGIGFGSNARTALITRGLVEMSRLGIAIGATLD
TFMGLAGLGDLILTCTDNQSRNRRFGILLGQGFEIHHAQKNVGKIIEGFYNIKEVYMLSVKHKVDMPITEQTYQILYQNK
NVHDAAHSLLERTQKEEKINGLK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=346, Percent_Identity=28.9017341040462, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24307999, Length=342, Percent_Identity=26.9005847953216, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=61.2121212121212, Blast_Score=446, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI32564399, Length=329, Percent_Identity=26.7477203647416, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210136, Length=326, Percent_Identity=26.3803680981595, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32564403, Length=326, Percent_Identity=26.3803680981595, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507425, Length=279, Percent_Identity=26.8817204301075, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193210134, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320181, Length=366, Percent_Identity=28.1420765027322, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324513, Length=351, Percent_Identity=27.0655270655271, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17136204, Length=331, Percent_Identity=28.7009063444109, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136202, Length=331, Percent_Identity=28.7009063444109, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136200, Length=331, Percent_Identity=28.7009063444109, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI22026922, Length=272, Percent_Identity=24.2647058823529, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362270, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45551945, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648969, Length=183, Percent_Identity=30.0546448087432, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BLOPB (Q491Y0)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278101.1
- ProteinModelPortal:   Q491Y0
- SMR:   Q491Y0
- STRING:   Q491Y0
- GeneID:   3563234
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_626
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- BioCyc:   CBLO291272:BPEN_626-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 37554; Mature: 37422

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 198-198 BINDING 113-113 BINDING 113-113 BINDING 146-146 BINDING 262-262 BINDING 288-288

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKYPKYPNITIIGAGSYGTAIAIALSRNGHSVLLWGHNAIHIQKLQINRCNQAYLPGI
CCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCEEEEEEEEECCCCCCCCCCC
AFPPSLYLEKSLSIALSTCRNLLIAVPSRVFGHVLMRLKPNLKSNTRIIIASKGLEPKTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
RLLQDVAYDILGKNIPIAIISGPTFARELAMGLPTAITLASNDTILSCDLQNILHCNKNF
HHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCEEEEEECCCEEEEECHHHHHHCCCCE
RIYSNTDTIGIQIAGVVKNIIAIGAGISDGIGFGSNARTALITRGLVEMSRLGIAIGATL
EEEECCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECHH
DTFMGLAGLGDLILTCTDNQSRNRRFGILLGQGFEIHHAQKNVGKIIEGFYNIKEVYMLS
HHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHEEEEE
VKHKVDMPITEQTYQILYQNKNVHDAAHSLLERTQKEEKINGLK
EHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIKYPKYPNITIIGAGSYGTAIAIALSRNGHSVLLWGHNAIHIQKLQINRCNQAYLPGI
CCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCEEEEEEEEECCCCCCCCCCC
AFPPSLYLEKSLSIALSTCRNLLIAVPSRVFGHVLMRLKPNLKSNTRIIIASKGLEPKTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHH
RLLQDVAYDILGKNIPIAIISGPTFARELAMGLPTAITLASNDTILSCDLQNILHCNKNF
HHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCEEEEEECCCEEEEECHHHHHHCCCCE
RIYSNTDTIGIQIAGVVKNIIAIGAGISDGIGFGSNARTALITRGLVEMSRLGIAIGATL
EEEECCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECHH
DTFMGLAGLGDLILTCTDNQSRNRRFGILLGQGFEIHHAQKNVGKIIEGFYNIKEVYMLS
HHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHEEEEE
VKHKVDMPITEQTYQILYQNKNVHDAAHSLLERTQKEEKINGLK
EHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA