Click here to switch to the map view.

The map label for this gene is yceL

Identifier: 71892232

GI number: 71892232

Start: 563140

End: 564363

Strand: Direct

Name: yceL

Synonym: BPEN_470

Alternate gene names: 71892232

Gene position: 563140-564363 (Clockwise)

Preceding gene: 71892230

Following gene: 71892235

Centisome position: 71.13

GC content: 32.11

Gene sequence:

>1224_bases
ATGTACACAATATCTAAAGCTAGAAGATTGGGTAAATGTTTTTTAATTATAGATAACATGTTTGTAGTTATAGGGTTTTA
TGTTGTTTTTCCATTGATTTCAATATATTTTGTCGAACAACTAGGATGGGGCGCTTTCTTAGTAGGATTTGCTTTAGGAT
TAAGACAATTTATTCAACAAGGACTAGGCATTTTTAGTGGCGCTTTTGCTGACAAATTAGGAGCTAAGCCTATGATTGTA
TCCGGGTTATTCATTCGTACTTTGGGATTTATTATAATGAGTGTTGCAAACACCCCCTTACTACTATGTCTTTCATGTAT
GTTATCAGCATTAGGTGGCACGTTATTTGATCCTCCACGTACCGCACTAGTAATTAAATTAGTGCGTCCATGGGAATTAG
GGCGGTTTTATTCTGTATTAATGCTAGAAGACAGTATGTGCGCCATCATCGGAATCGTGCTAGGTACATGGTTATTGCAA
TATAACTTTAAATTAGTATGTTTTACCGGAGCAATATTGTTTTTTATTGCCGGAGTGTTTAATGCCTGGCGGTTACCTGC
ATATAAAATTTCTAGTTCCCATGCTTCATTATTAGAAGGAATAAAAAAGGTACTTAATAATCAACGATTTGTAATTTATG
TCTTCACTCTAACTGGTTATTATATTTTATCAGCTCAAGTAATGTTAATGTTACCCATTCGCATTCATGAAGTATCCGGT
CAATTATCATATATCAAATGGATGTATATCATAGAAGCAATTTTATCTTTATTATTAATCATGCCTATAACTTGGTGGAG
CGAGAAATATTTCAAACTAGAAACACGCTTGATGGTAGGATTAATAACTATGATAATTAGTTTATTTCCTATTGGATTAG
TAAAAAACTTACATACTTTATTAATTTTAATTAGCTTATTCTATATAGGATCTATTATTGCCGAACCTGCAAGAGAAACT
TTGGGAGCACTACTAACGGACTATAAAGCACGTAGTAGTTACATAGGTTTTAGTAAATTAAGTCTAGCTTTAGGAGGTAC
TGTAGGATATAGTGGTAGTGGATGGTTGTATGATATTGGAAAAGAACAAAATTTTACGCAATTACCTTGGATCATTTTAA
GTATAATAGGACTGATTACGTTATTAGGACTATATTGTCAATTCAAATATTATTCTTTTCAATCTTTACTTAATAATAGT
CATAATAAGAAACGTAAACTGTGA

Upstream 100 bases:

>100_bases
TTTCATTACACTTAAAAATTAAAAAATTATAATTATTTTAAAATAATTTTCGTGCATACAGTAAATAATAATGTGTACGA
AAATACATAAACGGTGACTC

Downstream 100 bases:

>100_bases
TTAATAATACAACAACAATACGAATGCACCACTACCTACTAATTACTGGACCTTACGATGGATACAAATACAAATATTTT
TTCATACCTAAACAAAAACA

Product: multidrug resistance protein MdtH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MYTISKARRLGKCFLIIDNMFVVIGFYVVFPLISIYFVEQLGWGAFLVGFALGLRQFIQQGLGIFSGAFADKLGAKPMIV
SGLFIRTLGFIIMSVANTPLLLCLSCMLSALGGTLFDPPRTALVIKLVRPWELGRFYSVLMLEDSMCAIIGIVLGTWLLQ
YNFKLVCFTGAILFFIAGVFNAWRLPAYKISSSHASLLEGIKKVLNNQRFVIYVFTLTGYYILSAQVMLMLPIRIHEVSG
QLSYIKWMYIIEAILSLLLIMPITWWSEKYFKLETRLMVGLITMIISLFPIGLVKNLHTLLILISLFYIGSIIAEPARET
LGALLTDYKARSSYIGFSKLSLALGGTVGYSGSGWLYDIGKEQNFTQLPWIILSIIGLITLLGLYCQFKYYSFQSLLNNS
HNKKRKL

Sequences:

>Translated_407_residues
MYTISKARRLGKCFLIIDNMFVVIGFYVVFPLISIYFVEQLGWGAFLVGFALGLRQFIQQGLGIFSGAFADKLGAKPMIV
SGLFIRTLGFIIMSVANTPLLLCLSCMLSALGGTLFDPPRTALVIKLVRPWELGRFYSVLMLEDSMCAIIGIVLGTWLLQ
YNFKLVCFTGAILFFIAGVFNAWRLPAYKISSSHASLLEGIKKVLNNQRFVIYVFTLTGYYILSAQVMLMLPIRIHEVSG
QLSYIKWMYIIEAILSLLLIMPITWWSEKYFKLETRLMVGLITMIISLFPIGLVKNLHTLLILISLFYIGSIIAEPARET
LGALLTDYKARSSYIGFSKLSLALGGTVGYSGSGWLYDIGKEQNFTQLPWIILSIIGLITLLGLYCQFKYYSFQSLLNNS
HNKKRKL
>Mature_407_residues
MYTISKARRLGKCFLIIDNMFVVIGFYVVFPLISIYFVEQLGWGAFLVGFALGLRQFIQQGLGIFSGAFADKLGAKPMIV
SGLFIRTLGFIIMSVANTPLLLCLSCMLSALGGTLFDPPRTALVIKLVRPWELGRFYSVLMLEDSMCAIIGIVLGTWLLQ
YNFKLVCFTGAILFFIAGVFNAWRLPAYKISSSHASLLEGIKKVLNNQRFVIYVFTLTGYYILSAQVMLMLPIRIHEVSG
QLSYIKWMYIIEAILSLLLIMPITWWSEKYFKLETRLMVGLITMIISLFPIGLVKNLHTLLILISLFYIGSIIAEPARET
LGALLTDYKARSSYIGFSKLSLALGGTVGYSGSGWLYDIGKEQNFTQLPWIILSIIGLITLLGLYCQFKYYSFQSLLNNS
HNKKRKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily

Homologues:

Organism=Escherichia coli, GI87081828, Length=389, Percent_Identity=60.6683804627249, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTH_BLOPB (Q492K8)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277965.1
- ProteinModelPortal:   Q492K8
- STRING:   Q492K8
- GeneID:   3562966
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_470
- eggNOG:   COG0477
- HOGENOM:   HBG403347
- OMA:   LSMIPIG
- ProtClustDB:   PRK11646
- BioCyc:   CBLO291272:BPEN_470-MONOMER
- HAMAP:   MF_01529
- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 45819; Mature: 45819

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11a36f28)-; HASH(0x11db7e44)-; HASH(0x114a8734)-; HASH(0x1159a654)-; HASH(0x11bd4720)-; HASH(0x1120f21c)-; HASH(0x106d31a0)-; HASH(0x106845bc)-; HASH(0x111ded80)-; HASH(0x11dfc7bc)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCH
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA