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The map label for this gene is sbcB [H]

Identifier: 71892235

GI number: 71892235

Start: 567703

End: 569205

Strand: Direct

Name: sbcB [H]

Synonym: BPEN_476

Alternate gene names: 71892235

Gene position: 567703-569205 (Clockwise)

Preceding gene: 71892232

Following gene: 71892236

Centisome position: 71.71

GC content: 28.48

Gene sequence:

>1503_bases
ATGCTAACACATATTAATGTATCACAACCTAGTTTTTTTATTTATGATTATGAAACTTTTGGCATCAATCCAGCACTAGA
TAGACCAGCGCAATTTGCCGGAATTCGTACGAATAACACATTAAAACCTATAGAAAAAGAAAAAATCTTCTTTTGTCGCT
TATCAAATGATTATCTCCCCGATCCGCAATCCGTCCTCATTACTGGAATCGCTCCTCAAGATACCTTGCGTCATGGATTG
ATTGAATCTGAGTTCGCTCGTCGTATTCATCAACTATTTTGTATCCCTAAAACTTGTATTCTTGGATACAATAATATTCA
TTTTGACGATGAATTCAGTAGAAACATTTTTTATAGAAATTTTCATGACCCTTACTTATGGGCTTATCAGCGAGGAAATT
CCCGATGGGACTTATTACACGTACTACGTGCCTGTTATTCACTATGTCCAAATGGCATTACATGGCCATTGAACATTCAA
AATAAACCCAGCTTTCGTCTAAAAGATTTAACACAAGCAAATGCTATAAAACATCTCAGCGCACATGACGCTATGTCGGA
TGTCTACGCTACTTTAGAATTAACAAAATTAATAAAAGAAGCTCAGCCACAATTATTTCAATTTCTATTTGATCATCGTA
CCAAATATCAATTGCAAAAAATAATCGATCTAGATACCATGAATCCTTTGATATTTATCATGAACAAAATAAATAATAAA
TATAAAAATTTTATAACTTATATAGCTCCAATTTCTCGACATCCCATCAATCCTAACATTTTAATAGCATGCGATTTAAA
TGGTAATATAGATAATTTAGTTAATTTAAATATCAATACGATATATCAAAAATTGTACTCTAATCACATAACGATATATG
ATATTTTAAAAAAAATACCACTACGATTTATTCGATTAAATGCGTGCCCTATATTAATACCAATAAACTTTTTTGAAAAA
AACAATATTAACACTACTTACACCATGCAGCTCTCTACCAATTATCGATACTGTTTAAAAAATTTAAATTTTATTAGAAT
GCATGAAAATAGCGTCTATCTACGTAATAAAATAAATACACTATATACCATTATAGGATCTTACATCAATCAAAAAAATA
TATATAATAATCTTCATGTAGACAGTCAATTATATCATAGACTCTTCAATAATTCTGATCGTAAAATAATTGAAAGCATC
CGTAGAACTCATTCAAAAGAGTTGAAAAATTTATGCACTGACCACGTTGATACTCGTTTAAAACCACTCTTATTTTACTA
TAGAGCCCGAAATTTTCCTAATACTTTAAATTACCAAGAACAAAAAAAATGGTTGAACTATAAAAAAAATAAATTATTTA
ATACAGATCAATCAAAATCTTATAACGATAAACTAAATCAACTTCTGTCAATCTATAAATATAATGATCAAAAAATTACA
CTTCTACATTCATTACAAAAATATTATCAATATCTTTATGAAGTTCATTTTAATTTTTATTAA

Upstream 100 bases:

>100_bases
CTATATATAATACATACATATATACAATTAAATCTAATTAAATTATTATAATTTTAATAAATAATTTGATGATTATTCAA
TCAAAACAACTCACATCATT

Downstream 100 bases:

>100_bases
AAATTAGTTTTTAATTTTTTCATATATACATAATTCGGTATACTTTAATCTAAACTAGAATATATGAAAAAATTTGCAAA
AAAAAATCACATAATTTACA

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MLTHINVSQPSFFIYDYETFGINPALDRPAQFAGIRTNNTLKPIEKEKIFFCRLSNDYLPDPQSVLITGIAPQDTLRHGL
IESEFARRIHQLFCIPKTCILGYNNIHFDDEFSRNIFYRNFHDPYLWAYQRGNSRWDLLHVLRACYSLCPNGITWPLNIQ
NKPSFRLKDLTQANAIKHLSAHDAMSDVYATLELTKLIKEAQPQLFQFLFDHRTKYQLQKIIDLDTMNPLIFIMNKINNK
YKNFITYIAPISRHPINPNILIACDLNGNIDNLVNLNINTIYQKLYSNHITIYDILKKIPLRFIRLNACPILIPINFFEK
NNINTTYTMQLSTNYRYCLKNLNFIRMHENSVYLRNKINTLYTIIGSYINQKNIYNNLHVDSQLYHRLFNNSDRKIIESI
RRTHSKELKNLCTDHVDTRLKPLLFYYRARNFPNTLNYQEQKKWLNYKKNKLFNTDQSKSYNDKLNQLLSIYKYNDQKIT
LLHSLQKYYQYLYEVHFNFY

Sequences:

>Translated_500_residues
MLTHINVSQPSFFIYDYETFGINPALDRPAQFAGIRTNNTLKPIEKEKIFFCRLSNDYLPDPQSVLITGIAPQDTLRHGL
IESEFARRIHQLFCIPKTCILGYNNIHFDDEFSRNIFYRNFHDPYLWAYQRGNSRWDLLHVLRACYSLCPNGITWPLNIQ
NKPSFRLKDLTQANAIKHLSAHDAMSDVYATLELTKLIKEAQPQLFQFLFDHRTKYQLQKIIDLDTMNPLIFIMNKINNK
YKNFITYIAPISRHPINPNILIACDLNGNIDNLVNLNINTIYQKLYSNHITIYDILKKIPLRFIRLNACPILIPINFFEK
NNINTTYTMQLSTNYRYCLKNLNFIRMHENSVYLRNKINTLYTIIGSYINQKNIYNNLHVDSQLYHRLFNNSDRKIIESI
RRTHSKELKNLCTDHVDTRLKPLLFYYRARNFPNTLNYQEQKKWLNYKKNKLFNTDQSKSYNDKLNQLLSIYKYNDQKIT
LLHSLQKYYQYLYEVHFNFY
>Mature_500_residues
MLTHINVSQPSFFIYDYETFGINPALDRPAQFAGIRTNNTLKPIEKEKIFFCRLSNDYLPDPQSVLITGIAPQDTLRHGL
IESEFARRIHQLFCIPKTCILGYNNIHFDDEFSRNIFYRNFHDPYLWAYQRGNSRWDLLHVLRACYSLCPNGITWPLNIQ
NKPSFRLKDLTQANAIKHLSAHDAMSDVYATLELTKLIKEAQPQLFQFLFDHRTKYQLQKIIDLDTMNPLIFIMNKINNK
YKNFITYIAPISRHPINPNILIACDLNGNIDNLVNLNINTIYQKLYSNHITIYDILKKIPLRFIRLNACPILIPINFFEK
NNINTTYTMQLSTNYRYCLKNLNFIRMHENSVYLRNKINTLYTIIGSYINQKNIYNNLHVDSQLYHRLFNNSDRKIIESI
RRTHSKELKNLCTDHVDTRLKPLLFYYRARNFPNTLNYQEQKKWLNYKKNKLFNTDQSKSYNDKLNQLLSIYKYNDQKIT
LLHSLQKYYQYLYEVHFNFY

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=484, Percent_Identity=42.9752066115703, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 59709; Mature: 59709

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHINVSQPSFFIYDYETFGINPALDRPAQFAGIRTNNTLKPIEKEKIFFCRLSNDYLP
CCEEEECCCCEEEEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCC
DPQSVLITGIAPQDTLRHGLIESEFARRIHQLFCIPKTCILGYNNIHFDDEFSRNIFYRN
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCEEEC
FHDPYLWAYQRGNSRWDLLHVLRACYSLCPNGITWPLNIQNKPSFRLKDLTQANAIKHLS
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
AHDAMSDVYATLELTKLIKEAQPQLFQFLFDHRTKYQLQKIIDLDTMNPLIFIMNKINNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
YKNFITYIAPISRHPINPNILIACDLNGNIDNLVNLNINTIYQKLYSNHITIYDILKKIP
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHCC
LRFIRLNACPILIPINFFEKNNINTTYTMQLSTNYRYCLKNLNFIRMHENSVYLRNKINT
HHEEEECCCEEEEEEEEEECCCCCEEEEEEEECCHHHHHCCCCEEEEECCCEEEHHHHHH
LYTIIGSYINQKNIYNNLHVDSQLYHRLFNNSDRKIIESIRRTHSKELKNLCTDHVDTRL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLLFYYRARNFPNTLNYQEQKKWLNYKKNKLFNTDQSKSYNDKLNQLLSIYKYNDQKIT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEH
LLHSLQKYYQYLYEVHFNFY
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTHINVSQPSFFIYDYETFGINPALDRPAQFAGIRTNNTLKPIEKEKIFFCRLSNDYLP
CCEEEECCCCEEEEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEEECCCCCC
DPQSVLITGIAPQDTLRHGLIESEFARRIHQLFCIPKTCILGYNNIHFDDEFSRNIFYRN
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCEEEC
FHDPYLWAYQRGNSRWDLLHVLRACYSLCPNGITWPLNIQNKPSFRLKDLTQANAIKHLS
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
AHDAMSDVYATLELTKLIKEAQPQLFQFLFDHRTKYQLQKIIDLDTMNPLIFIMNKINNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
YKNFITYIAPISRHPINPNILIACDLNGNIDNLVNLNINTIYQKLYSNHITIYDILKKIP
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHCC
LRFIRLNACPILIPINFFEKNNINTTYTMQLSTNYRYCLKNLNFIRMHENSVYLRNKINT
HHEEEECCCEEEEEEEEEECCCCCEEEEEEEECCHHHHHCCCCEEEEECCCEEEHHHHHH
LYTIIGSYINQKNIYNNLHVDSQLYHRLFNNSDRKIIESIRRTHSKELKNLCTDHVDTRL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLLFYYRARNFPNTLNYQEQKKWLNYKKNKLFNTDQSKSYNDKLNQLLSIYKYNDQKIT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEH
LLHSLQKYYQYLYEVHFNFY
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]