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The map label for this gene is htpX [H]

Identifier: 71892225

GI number: 71892225

Start: 550270

End: 551205

Strand: Reverse

Name: htpX [H]

Synonym: BPEN_463

Alternate gene names: 71892225

Gene position: 551205-550270 (Counterclockwise)

Preceding gene: 71892226

Following gene: 71892224

Centisome position: 69.63

GC content: 30.88

Gene sequence:

>936_bases
ATGATGCGCATTATATTGTTTTTAATTACTAATTTATCAGTAATGATATTATTTGGTAGTATATTGAGCTTACTGGGATG
TTGGTCCTCTACTACATTTGAATTAATGAAAATGGCTGGAATATTTGGTTTCGGAGGAGCGTTTATTTCCTTATTATTAT
CTAAATCTATAGCTTTATCTGCAGTTAATGGATTGATCATTAGTCAAGCATCTAATGATGTAGAGCATTTATTATTGAAA
ATAATAAATGTTCAGGCTAAGAAATTAAATATTGTTGCACCACAGTTGGCAATTTACGATTCTATAGATATGAATGCTTT
TGCTACGGGAGCAAGAAGAAATTCGGCATTAATAGCCGTTAGTACTGGTCTTTTAAAAAATATGAATACAGAGTCAATTG
AGGCTGTTGTTGCTCATGAAATGAATCATATCGCTTCTGGCGATATGATTACTATGACTCTTATTCAAGGTATAATTAAT
ACTTTTGTGATTTTTGTATCACGTAGTCTTGCCGCGATGGTCTTTTATTGGACTTCTTTTATAAATGACCAAAATGATGA
GCAGTTTGATGTTCGCAGTAGTAATCATTGTGATATAAACAATTCTATGGTGTATATTATTGTGTCAATAATTTTAGAAG
TTGTGTTCGGCATGTTTGCTAGTATCATCGTGTTTTGGTTTTCTCGTTATCGTGAATTTTATGCGGATGCTGGTGCTGCT
AAATTAGTAGGATGCAGAAATGTTATTGCTGCCTTACAAGAATTAAAACATAGTTATACACTTAACACATCTAATCATAT
TACTACTTTGTATATTAATAGTGTAAAAAAAAGTATATTAAGTGATTTGTTCGCATCTCATCCATCTTTAGATAAACGGA
TAGAAGCGTTACAACATGGTACTTATTTAAATAAGTCGTCTTATTTTTTTAAATAA

Upstream 100 bases:

>100_bases
TTTTTATTGTATATAAAAGATTCTTTAAAAATTGAAATTATCTATATCTAGATATTATTTAAATATTTAGGTATCTTTAG
TAAAGAGGAAGATGGTTTTT

Downstream 100 bases:

>100_bases
ATAATTTTGATTAAAGATGAAAATGATTGTTTTTATGAGTTTATGTACAGGGTTATGTGTCATATGATTTACAAAGTAAA
AAATAAATGCTATCTTACCC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MMRIILFLITNLSVMILFGSILSLLGCWSSTTFELMKMAGIFGFGGAFISLLLSKSIALSAVNGLIISQASNDVEHLLLK
IINVQAKKLNIVAPQLAIYDSIDMNAFATGARRNSALIAVSTGLLKNMNTESIEAVVAHEMNHIASGDMITMTLIQGIIN
TFVIFVSRSLAAMVFYWTSFINDQNDEQFDVRSSNHCDINNSMVYIIVSIILEVVFGMFASIIVFWFSRYREFYADAGAA
KLVGCRNVIAALQELKHSYTLNTSNHITTLYINSVKKSILSDLFASHPSLDKRIEALQHGTYLNKSSYFFK

Sequences:

>Translated_311_residues
MMRIILFLITNLSVMILFGSILSLLGCWSSTTFELMKMAGIFGFGGAFISLLLSKSIALSAVNGLIISQASNDVEHLLLK
IINVQAKKLNIVAPQLAIYDSIDMNAFATGARRNSALIAVSTGLLKNMNTESIEAVVAHEMNHIASGDMITMTLIQGIIN
TFVIFVSRSLAAMVFYWTSFINDQNDEQFDVRSSNHCDINNSMVYIIVSIILEVVFGMFASIIVFWFSRYREFYADAGAA
KLVGCRNVIAALQELKHSYTLNTSNHITTLYINSVKKSILSDLFASHPSLDKRIEALQHGTYLNKSSYFFK
>Mature_311_residues
MMRIILFLITNLSVMILFGSILSLLGCWSSTTFELMKMAGIFGFGGAFISLLLSKSIALSAVNGLIISQASNDVEHLLLK
IINVQAKKLNIVAPQLAIYDSIDMNAFATGARRNSALIAVSTGLLKNMNTESIEAVVAHEMNHIASGDMITMTLIQGIIN
TFVIFVSRSLAAMVFYWTSFINDQNDEQFDVRSSNHCDINNSMVYIIVSIILEVVFGMFASIIVFWFSRYREFYADAGAA
KLVGCRNVIAALQELKHSYTLNTSNHITTLYINSVKKSILSDLFASHPSLDKRIEALQHGTYLNKSSYFFK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=304, Percent_Identity=54.2763157894737, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 34502; Mature: 34502

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIILFLITNLSVMILFGSILSLLGCWSSTTFELMKMAGIFGFGGAFISLLLSKSIALS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNGLIISQASNDVEHLLLKIINVQAKKLNIVAPQLAIYDSIDMNAFATGARRNSALIAV
HHHHHHEECCCCHHHHHHHHHHHHHHHHEEEECCHHHHHCCCCCCHHHCCCCCCCEEEEE
STGLLKNMNTESIEAVVAHEMNHIASGDMITMTLIQGIINTFVIFVSRSLAAMVFYWTSF
EHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDQNDEQFDVRSSNHCDINNSMVYIIVSIILEVVFGMFASIIVFWFSRYREFYADAGAA
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLVGCRNVIAALQELKHSYTLNTSNHITTLYINSVKKSILSDLFASHPSLDKRIEALQHG
HHHHHHHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
TYLNKSSYFFK
CCCCCCCCCCC
>Mature Secondary Structure
MMRIILFLITNLSVMILFGSILSLLGCWSSTTFELMKMAGIFGFGGAFISLLLSKSIALS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNGLIISQASNDVEHLLLKIINVQAKKLNIVAPQLAIYDSIDMNAFATGARRNSALIAV
HHHHHHEECCCCHHHHHHHHHHHHHHHHEEEECCHHHHHCCCCCCHHHCCCCCCCEEEEE
STGLLKNMNTESIEAVVAHEMNHIASGDMITMTLIQGIINTFVIFVSRSLAAMVFYWTSF
EHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INDQNDEQFDVRSSNHCDINNSMVYIIVSIILEVVFGMFASIIVFWFSRYREFYADAGAA
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLVGCRNVIAALQELKHSYTLNTSNHITTLYINSVKKSILSDLFASHPSLDKRIEALQHG
HHHHHHHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
TYLNKSSYFFK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]