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The map label for this gene is gapA [H]

Identifier: 71892213

GI number: 71892213

Start: 536840

End: 537838

Strand: Direct

Name: gapA [H]

Synonym: BPEN_451

Alternate gene names: 71892213

Gene position: 536840-537838 (Clockwise)

Preceding gene: 71892212

Following gene: 71892214

Centisome position: 67.81

GC content: 33.43

Gene sequence:

>999_bases
ATGGCTATTAAAATAGGTATTAATGGGTTTGGTAGAATTGGTCGCGTTATTTTTAGAACTGTACAAGACAGAAAAGACGC
AGATGTTGTCGCCATTAATGATTTACTCGACATTGAACATATCGCATATATGTTGAAATATGATTCAACTCATGGACGAT
TTAAAGGAACAATTAATGTACATGGTGACCATCTAATCATTAATGATAAAGTTGTGCACTACACTTCAGAAAAAGATCCA
AAAAACTTATATTGGGGAAATTTTGATATTGATGTTGTTACTGAATCTACAGGAATGTTTTTAACTGAAGAAAAAGCTCA
CGGACATATCTTCTCTGGAGCCCGTAAAGTAGTATTAACAGCTCCATCAAAAGATGATACACCAATGTTTGTTATGGGAG
TTAATAACCATCTCTACAAGGGAGAAAAAATAATATCTAATGCATCTTGCACTACTAATTGTTTAGCTCCATTAGCTAAA
GTTATTAACGACAATTTTGGCATCATTGAAGGTATAATGACTACTGTTCATGCTACCACCGCTACTCAAAAAACTGTTGA
TGCCCCAATACATAATGATTGGAGAAGTGGACGTGGTGCCTACCAAAATATAATTCCATCTTCTACTGGAGCGACACGAG
CATTAGGAAAAGTTATTAAAGAGCTAGACGGTAAATTAACTGGAATATCATTCCGAGTCCCTATTCCAAATGTTTCTGTT
GTTGACTTTACCGTCCGTTTAGAAAAATCCGCTTCTTATAAAAATATTTGCGATGTTATTAAAAACGCCGCTTACGGAAA
TTTAAAAGGAATTATAGGATATACTGATGAAAAAGTGGTATCTAGCGATTTTAACGGAGAAAAATTAATCTCTATTTTCG
ACGCACAAGCAAGCATCTTATTAAATAATCATTTCGCTAAACTAATATCTTGGTATGATAATGAAACAGGCTACTCTGAT
AAAGTAATCGATTTAAGTGTATATATTACAAAACATTAA

Upstream 100 bases:

>100_bases
TTCTTATTGAGAATTCGATATATAAAACAATATTCCATGCCTTCATTTAAAATTTACAACATAACATATAATCACAACTA
AAACAGGAGCATATAATAAT

Downstream 100 bases:

>100_bases
ATAATATCATCCAATAAATACTTCAACCTATTACATAGGTAATCTCATTAATGATTAGAATCAAATAAAAACAGTTTAAT
GACTTTCAAATAAGAGATGT

Product: glyceraldehyde 3-phosphate dehydrogenase A

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAIKIGINGFGRIGRVIFRTVQDRKDADVVAINDLLDIEHIAYMLKYDSTHGRFKGTINVHGDHLIINDKVVHYTSEKDP
KNLYWGNFDIDVVTESTGMFLTEEKAHGHIFSGARKVVLTAPSKDDTPMFVMGVNNHLYKGEKIISNASCTTNCLAPLAK
VINDNFGIIEGIMTTVHATTATQKTVDAPIHNDWRSGRGAYQNIIPSSTGATRALGKVIKELDGKLTGISFRVPIPNVSV
VDFTVRLEKSASYKNICDVIKNAAYGNLKGIIGYTDEKVVSSDFNGEKLISIFDAQASILLNNHFAKLISWYDNETGYSD
KVIDLSVYITKH

Sequences:

>Translated_332_residues
MAIKIGINGFGRIGRVIFRTVQDRKDADVVAINDLLDIEHIAYMLKYDSTHGRFKGTINVHGDHLIINDKVVHYTSEKDP
KNLYWGNFDIDVVTESTGMFLTEEKAHGHIFSGARKVVLTAPSKDDTPMFVMGVNNHLYKGEKIISNASCTTNCLAPLAK
VINDNFGIIEGIMTTVHATTATQKTVDAPIHNDWRSGRGAYQNIIPSSTGATRALGKVIKELDGKLTGISFRVPIPNVSV
VDFTVRLEKSASYKNICDVIKNAAYGNLKGIIGYTDEKVVSSDFNGEKLISIFDAQASILLNNHFAKLISWYDNETGYSD
KVIDLSVYITKH
>Mature_331_residues
AIKIGINGFGRIGRVIFRTVQDRKDADVVAINDLLDIEHIAYMLKYDSTHGRFKGTINVHGDHLIINDKVVHYTSEKDPK
NLYWGNFDIDVVTESTGMFLTEEKAHGHIFSGARKVVLTAPSKDDTPMFVMGVNNHLYKGEKIISNASCTTNCLAPLAKV
INDNFGIIEGIMTTVHATTATQKTVDAPIHNDWRSGRGAYQNIIPSSTGATRALGKVIKELDGKLTGISFRVPIPNVSVV
DFTVRLEKSASYKNICDVIKNAAYGNLKGIIGYTDEKVVSSDFNGEKLISIFDAQASILLNNHFAKLISWYDNETGYSDK
VIDLSVYITKH

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=58.9665653495441, Blast_Score=397, Evalue=1e-111,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=54.8484848484848, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=67.0694864048338, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=34.9397590361446, Blast_Score=229, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=59.5808383233533, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=59.5808383233533, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=57.957957957958, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=57.957957957958, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=59.5166163141994, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=56.797583081571, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=56.797583081571, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=60.6707317073171, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=60.6707317073171, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=59.7560975609756, Blast_Score=393, Evalue=1e-110,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=59.7560975609756, Blast_Score=393, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=57.6687116564417, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36670; Mature: 36539

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIGINGFGRIGRVIFRTVQDRKDADVVAINDLLDIEHIAYMLKYDSTHGRFKGTINV
CEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHEEEEEECCCCCEEEEEEEE
HGDHLIINDKVVHYTSEKDPKNLYWGNFDIDVVTESTGMFLTEEKAHGHIFSGARKVVLT
CCCEEEECCEEEEEECCCCCCCEECCCEEEEEEECCCCEEEEECCCCCEEECCCEEEEEE
APSKDDTPMFVMGVNNHLYKGEKIISNASCTTNCLAPLAKVINDNFGIIEGIMTTVHATT
CCCCCCCCEEEEECCCCEECCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
ATQKTVDAPIHNDWRSGRGAYQNIIPSSTGATRALGKVIKELDGKLTGISFRVPIPNVSV
CCCHHCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEE
VDFTVRLEKSASYKNICDVIKNAAYGNLKGIIGYTDEKVVSSDFNGEKLISIFDAQASIL
EEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCCCCEEEEEECCCEEEE
LNNHFAKLISWYDNETGYSDKVIDLSVYITKH
EHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
AIKIGINGFGRIGRVIFRTVQDRKDADVVAINDLLDIEHIAYMLKYDSTHGRFKGTINV
EEEEECCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHEEEEEECCCCCEEEEEEEE
HGDHLIINDKVVHYTSEKDPKNLYWGNFDIDVVTESTGMFLTEEKAHGHIFSGARKVVLT
CCCEEEECCEEEEEECCCCCCCEECCCEEEEEEECCCCEEEEECCCCCEEECCCEEEEEE
APSKDDTPMFVMGVNNHLYKGEKIISNASCTTNCLAPLAKVINDNFGIIEGIMTTVHATT
CCCCCCCCEEEEECCCCEECCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
ATQKTVDAPIHNDWRSGRGAYQNIIPSSTGATRALGKVIKELDGKLTGISFRVPIPNVSV
CCCHHCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEE
VDFTVRLEKSASYKNICDVIKNAAYGNLKGIIGYTDEKVVSSDFNGEKLISIFDAQASIL
EEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCCCCEEEEEECCCEEEE
LNNHFAKLISWYDNETGYSDKVIDLSVYITKH
EHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]