Click here to switch to the map view.

The map label for this gene is asnC

Identifier: 71892195

GI number: 71892195

Start: 508697

End: 510109

Strand: Direct

Name: asnC

Synonym: BPEN_433

Alternate gene names: 71892195

Gene position: 508697-510109 (Clockwise)

Preceding gene: 71892194

Following gene: 71892196

Centisome position: 64.26

GC content: 31.42

Gene sequence:

>1413_bases
ATGAATGTAGTATCAGTAGTAGATATACTAAGCGGTCATGTATCAAAAAATACTGAAATTACTATACAAGGTTGGATTCG
AACCCGACGAGATTCTAAAGCTAAAATCTCCTTCCTAGATTTATACGATGGTTCATGTATCAACTCGTTACAAATAATTG
CGTATGATAAGTTACATAACTATAAAAATGAGATATTGCGTTTAACTAGCGGTTGCTCAGTTATAATTGTGGGAATAATA
GTTAAATCCATTGGTATAAAACAACATGTTGAAGTAATTGCAAAAAACATTAAAATATTAGGATGGATAGAAGATCCTAG
TACTTACCCAATAACTGCCAAAAAACATACTATGGAATATCTGCGTGAAGTTTCTCATCTGAGACCACGTACTAATACAA
TTGGTGCTGTTGCTCGCATCAGAGACACATTATCACAAGCTATTCATAACTTTTTGCATAAACAAGGATTTATATGGATT
CCTACTCCTATAATTACTGCATGTGACACTGAAGGAAGTAGCAAAATGTTCTGCGTATCTACCTCAGAAACTCAAAAAAT
TTTAAATAATCCAAACGAAAAATTACATCATACTCACGACACCACCTATGACTTTTTCAGTAAAAAAGCTTTTTTAACAG
TATCAGGTCAATTAAATGCAGAAGCTTATGCTTGTGCGCTATCAAAAGTATATACTTTTGGTCCAACTTTTAGAGCAGAA
TATTCCAATACTAATCGACATTTAGCTGAATTTTGGATGATAGAACCAGAAGCTGCATTTATGACCTTAGATGATATTAT
TATTTTAGCAGAATCTTTACTTAAAAACATCATCAGAATACTCCTTGAAAAACGTTCCGACGATATAAAATACTTAGTTG
ATAAAATAAACAAAAATATTATTACTATCCTGGAAAATTTCTCTGAGATTAAATTCAATCATATAGAATATACTGAAGCA
ATAAAATTACTAGAAATATGCAACAGAAAATTTAATAATCCAATCCACTGGGGAACAGATTTGTTCTCTGAACATGAAAA
ATATCTGTCGGAAGAATATTTTAAATCCCCAGTAATAATAAAAAACTTTCCAAAAAACATCAAAGCTTTCTACATGCGTT
TAAACGATGATAATAAAACTGTGGCATCTATGGATATTTTAGTTCCCGGGATTGGTGAAATAATTGGAGGTTCTCAGAGA
GAAGAAAGATTATCAAAATTAGATCAAAGATTACAAGAAAACTGTTTAACACAAGAAAATTATTGGTGGTATCGTGATCT
ACGACGCTACGGAACAGTGCCTCATTCAGGGTTCGGATTAGGTTTTGAAAGATTAATGATATATGTAACAGGAATAAAAA
ATATTAGAGATGTCATTCCATTTCCCAGAACCTCAAAAAACATTAATTTTTGA

Upstream 100 bases:

>100_bases
ATATACTATTTCAAATACAATTATCAGTATATGATGTTTAATATTTACAATATAACTAAAAATTAAAATATTATTAGTCT
AAAAATCAGGAGACTATAAA

Downstream 100 bases:

>100_bases
CAAAATCTATAGGCATAGACATAAATACATAAACAAAATAAATCTAATTATATAATGCTTAAAAATAATTCATATATACA
TATATTATATGCATGATTAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNVVSVVDILSGHVSKNTEITIQGWIRTRRDSKAKISFLDLYDGSCINSLQIIAYDKLHNYKNEILRLTSGCSVIIVGII
VKSIGIKQHVEVIAKNIKILGWIEDPSTYPITAKKHTMEYLREVSHLRPRTNTIGAVARIRDTLSQAIHNFLHKQGFIWI
PTPIITACDTEGSSKMFCVSTSETQKILNNPNEKLHHTHDTTYDFFSKKAFLTVSGQLNAEAYACALSKVYTFGPTFRAE
YSNTNRHLAEFWMIEPEAAFMTLDDIIILAESLLKNIIRILLEKRSDDIKYLVDKINKNIITILENFSEIKFNHIEYTEA
IKLLEICNRKFNNPIHWGTDLFSEHEKYLSEEYFKSPVIIKNFPKNIKAFYMRLNDDNKTVASMDILVPGIGEIIGGSQR
EERLSKLDQRLQENCLTQENYWWYRDLRRYGTVPHSGFGLGFERLMIYVTGIKNIRDVIPFPRTSKNINF

Sequences:

>Translated_470_residues
MNVVSVVDILSGHVSKNTEITIQGWIRTRRDSKAKISFLDLYDGSCINSLQIIAYDKLHNYKNEILRLTSGCSVIIVGII
VKSIGIKQHVEVIAKNIKILGWIEDPSTYPITAKKHTMEYLREVSHLRPRTNTIGAVARIRDTLSQAIHNFLHKQGFIWI
PTPIITACDTEGSSKMFCVSTSETQKILNNPNEKLHHTHDTTYDFFSKKAFLTVSGQLNAEAYACALSKVYTFGPTFRAE
YSNTNRHLAEFWMIEPEAAFMTLDDIIILAESLLKNIIRILLEKRSDDIKYLVDKINKNIITILENFSEIKFNHIEYTEA
IKLLEICNRKFNNPIHWGTDLFSEHEKYLSEEYFKSPVIIKNFPKNIKAFYMRLNDDNKTVASMDILVPGIGEIIGGSQR
EERLSKLDQRLQENCLTQENYWWYRDLRRYGTVPHSGFGLGFERLMIYVTGIKNIRDVIPFPRTSKNINF
>Mature_470_residues
MNVVSVVDILSGHVSKNTEITIQGWIRTRRDSKAKISFLDLYDGSCINSLQIIAYDKLHNYKNEILRLTSGCSVIIVGII
VKSIGIKQHVEVIAKNIKILGWIEDPSTYPITAKKHTMEYLREVSHLRPRTNTIGAVARIRDTLSQAIHNFLHKQGFIWI
PTPIITACDTEGSSKMFCVSTSETQKILNNPNEKLHHTHDTTYDFFSKKAFLTVSGQLNAEAYACALSKVYTFGPTFRAE
YSNTNRHLAEFWMIEPEAAFMTLDDIIILAESLLKNIIRILLEKRSDDIKYLVDKINKNIITILENFSEIKFNHIEYTEA
IKLLEICNRKFNNPIHWGTDLFSEHEKYLSEEYFKSPVIIKNFPKNIKAFYMRLNDDNKTVASMDILVPGIGEIIGGSQR
EERLSKLDQRLQENCLTQENYWWYRDLRRYGTVPHSGFGLGFERLMIYVTGIKNIRDVIPFPRTSKNINF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=43.1034482758621, Blast_Score=358, Evalue=5e-99,
Organism=Homo sapiens, GI4758762, Length=463, Percent_Identity=25.9179265658747, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI45439306, Length=351, Percent_Identity=28.7749287749288, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1787161, Length=470, Percent_Identity=60.6382978723404, Blast_Score=651, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71984122, Length=459, Percent_Identity=28.7581699346405, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17556372, Length=435, Percent_Identity=30.3448275862069, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=502, Percent_Identity=26.0956175298805, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319872, Length=487, Percent_Identity=35.1129363449692, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321807, Length=457, Percent_Identity=29.1028446389497, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=350, Percent_Identity=28.8571428571429, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922416, Length=449, Percent_Identity=34.2984409799555, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI19921528, Length=471, Percent_Identity=26.963906581741, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17136276, Length=351, Percent_Identity=27.3504273504274, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_BLOPB (Q492P3)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277928.1
- HSSP:   O57980
- ProteinModelPortal:   Q492P3
- SMR:   Q492P3
- STRING:   Q492P3
- GeneID:   3562743
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_433
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   CBLO291272:BPEN_433-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 54211; Mature: 54211

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVSVVDILSGHVSKNTEITIQGWIRTRRDSKAKISFLDLYDGSCINSLQIIAYDKLHN
CCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHH
YKNEILRLTSGCSVIIVGIIVKSIGIKQHVEVIAKNIKILGWIEDPSTYPITAKKHTMEY
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHH
LREVSHLRPRTNTIGAVARIRDTLSQAIHNFLHKQGFIWIPTPIITACDTEGSSKMFCVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCEEEEE
TSETQKILNNPNEKLHHTHDTTYDFFSKKAFLTVSGQLNAEAYACALSKVYTFGPTFRAE
CHHHHHHHCCCCHHHCCCCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
YSNTNRHLAEFWMIEPEAAFMTLDDIIILAESLLKNIIRILLEKRSDDIKYLVDKINKNI
CCCCCCEEEHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
ITILENFSEIKFNHIEYTEAIKLLEICNRKFNNPIHWGTDLFSEHEKYLSEEYFKSPVII
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
KNFPKNIKAFYMRLNDDNKTVASMDILVPGIGEIIGGSQREERLSKLDQRLQENCLTQEN
ECCCCCCEEEEEEECCCCCEEEEEHEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
YWWYRDLRRYGTVPHSGFGLGFERLMIYVTGIKNIRDVIPFPRTSKNINF
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNVVSVVDILSGHVSKNTEITIQGWIRTRRDSKAKISFLDLYDGSCINSLQIIAYDKLHN
CCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHH
YKNEILRLTSGCSVIIVGIIVKSIGIKQHVEVIAKNIKILGWIEDPSTYPITAKKHTMEY
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHH
LREVSHLRPRTNTIGAVARIRDTLSQAIHNFLHKQGFIWIPTPIITACDTEGSSKMFCVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCEEEEE
TSETQKILNNPNEKLHHTHDTTYDFFSKKAFLTVSGQLNAEAYACALSKVYTFGPTFRAE
CHHHHHHHCCCCHHHCCCCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEE
YSNTNRHLAEFWMIEPEAAFMTLDDIIILAESLLKNIIRILLEKRSDDIKYLVDKINKNI
CCCCCCEEEHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
ITILENFSEIKFNHIEYTEAIKLLEICNRKFNNPIHWGTDLFSEHEKYLSEEYFKSPVII
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
KNFPKNIKAFYMRLNDDNKTVASMDILVPGIGEIIGGSQREERLSKLDQRLQENCLTQEN
ECCCCCCEEEEEEECCCCCEEEEEHEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
YWWYRDLRRYGTVPHSGFGLGFERLMIYVTGIKNIRDVIPFPRTSKNINF
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA