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The map label for this gene is gpmA

Identifier: 71892120

GI number: 71892120

Start: 417047

End: 417745

Strand: Direct

Name: gpmA

Synonym: BPEN_352

Alternate gene names: 71892120

Gene position: 417047-417745 (Clockwise)

Preceding gene: 71892118

Following gene: 71892121

Centisome position: 52.68

GC content: 30.76

Gene sequence:

>699_bases
ATGCATATAACTAAATTAGTTTTAATAAGACACGGAGAAAGTCAATGGAACAAAGAAAATAGATTCACTGGATGGGTTGA
TGTAGACTTATCAGAAAAAGGACGTTCTGAAGCGCAATGCGCTGGTAGAATATTAAAAAAAAATGGATTTTTTTTTAATT
ATGGATATACTTCAGTATTAAAACGAGCAATTCATACTTTATGGATCATATTAGATCAATTAGATCAAGCATGGCTACCA
ATAGAAAAATCTTGGCGACTCAATGAACGTCATTATGGGGCACTGCAAGGATTAAATAAAGATGAAGCCATAAAAGAATA
TGGATACAAAACAATTCAAAAATGGCGTCGTAGTTTCAATGTTATTCCTCCAAATATTTGTGGTGGAAATAATCAGTTTA
TTGCAACAAATGACAATCGTTATGCTAACATCAGTACTGATGAATTACCTAGTAGTGAAAGTTTAGAACTAACCTTAAAA
AGAGTAATCCCTTATTGGAACCAATCCATAATACCTCATATCAAAAAAGGTCAAACAATTATTATCGTTGCCCATGGAAA
TTCTATACGCGCTATAATAAAGTTTCTCAATCACTTAAATGAATCAGAAATATTTCAAATTAATGTGCCAACAGGTGTTC
CGCTAATATATGAATTTGACAAAAAAGCAAATACTGTTCAACATTATTATTTAAAATAA

Upstream 100 bases:

>100_bases
TTTCGATATTACGCATCATACAATTAAAATAGCCAATCTAAAACAAGCAGTATATAATCACTTCACATGTTCGTAAACAA
AAAAAATAAGAGAACAAATT

Downstream 100 bases:

>100_bases
TTATTTAAATAATAATTTATTTTCAGTTATTACTTTTGATAAAGTAATATATACGATTATTTAATATTCATTTGAACTTC
ACATTCATTTTTAAAATGAT

Product: phosphoglycerate mutase 1

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MHITKLVLIRHGESQWNKENRFTGWVDVDLSEKGRSEAQCAGRILKKNGFFFNYGYTSVLKRAIHTLWIILDQLDQAWLP
IEKSWRLNERHYGALQGLNKDEAIKEYGYKTIQKWRRSFNVIPPNICGGNNQFIATNDNRYANISTDELPSSESLELTLK
RVIPYWNQSIIPHIKKGQTIIIVAHGNSIRAIIKFLNHLNESEIFQINVPTGVPLIYEFDKKANTVQHYYLK

Sequences:

>Translated_232_residues
MHITKLVLIRHGESQWNKENRFTGWVDVDLSEKGRSEAQCAGRILKKNGFFFNYGYTSVLKRAIHTLWIILDQLDQAWLP
IEKSWRLNERHYGALQGLNKDEAIKEYGYKTIQKWRRSFNVIPPNICGGNNQFIATNDNRYANISTDELPSSESLELTLK
RVIPYWNQSIIPHIKKGQTIIIVAHGNSIRAIIKFLNHLNESEIFQINVPTGVPLIYEFDKKANTVQHYYLK
>Mature_232_residues
MHITKLVLIRHGESQWNKENRFTGWVDVDLSEKGRSEAQCAGRILKKNGFFFNYGYTSVLKRAIHTLWIILDQLDQAWLP
IEKSWRLNERHYGALQGLNKDEAIKEYGYKTIQKWRRSFNVIPPNICGGNNQFIATNDNRYANISTDELPSSESLELTLK
RVIPYWNQSIIPHIKKGQTIIIVAHGNSIRAIIKFLNHLNESEIFQINVPTGVPLIYEFDKKANTVQHYYLK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI4505753, Length=228, Percent_Identity=49.5614035087719, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI50593010, Length=223, Percent_Identity=47.9820627802691, Blast_Score=244, Evalue=5e-65,
Organism=Homo sapiens, GI71274132, Length=228, Percent_Identity=47.3684210526316, Blast_Score=231, Evalue=4e-61,
Organism=Homo sapiens, GI4502445, Length=235, Percent_Identity=47.2340425531915, Blast_Score=231, Evalue=5e-61,
Organism=Homo sapiens, GI40353764, Length=235, Percent_Identity=47.2340425531915, Blast_Score=231, Evalue=5e-61,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=50.9090909090909, Blast_Score=171, Evalue=4e-43,
Organism=Escherichia coli, GI1786970, Length=231, Percent_Identity=61.038961038961, Blast_Score=322, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6322697, Length=230, Percent_Identity=45.2173913043478, Blast_Score=224, Evalue=8e-60,
Organism=Saccharomyces cerevisiae, GI6324516, Length=275, Percent_Identity=31.6363636363636, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320183, Length=271, Percent_Identity=28.7822878228782, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646216, Length=219, Percent_Identity=44.7488584474886, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI85725270, Length=219, Percent_Identity=49.3150684931507, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI85725272, Length=219, Percent_Identity=49.3150684931507, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24650981, Length=219, Percent_Identity=49.3150684931507, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=37.2727272727273, Blast_Score=160, Evalue=8e-40,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=37.2727272727273, Blast_Score=160, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=37.2727272727273, Blast_Score=160, Evalue=9e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_BLOPB (Q492W5)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277852.1
- ProteinModelPortal:   Q492W5
- SMR:   Q492W5
- STRING:   Q492W5
- GeneID:   3562809
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_352
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   IRTLWFV
- ProtClustDB:   CLSK280823
- BioCyc:   CBLO291272:BPEN_352-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 26998; Mature: 26998

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 11-11 ACT_SITE 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITKLVLIRHGESQWNKENRFTGWVDVDLSEKGRSEAQCAGRILKKNGFFFNYGYTSVL
CCCEEEEEEECCCHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEECCHHHHH
KRAIHTLWIILDQLDQAWLPIEKSWRLNERHYGALQGLNKDEAIKEYGYKTIQKWRRSFN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCHHHHHHHHHHCC
VIPPNICGGNNQFIATNDNRYANISTDELPSSESLELTLKRVIPYWNQSIIPHIKKGQTI
CCCCCCCCCCCCEEEECCCEEEECCHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
IIVAHGNSIRAIIKFLNHLNESEIFQINVPTGVPLIYEFDKKANTVQHYYLK
EEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEECC
>Mature Secondary Structure
MHITKLVLIRHGESQWNKENRFTGWVDVDLSEKGRSEAQCAGRILKKNGFFFNYGYTSVL
CCCEEEEEEECCCHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEECCHHHHH
KRAIHTLWIILDQLDQAWLPIEKSWRLNERHYGALQGLNKDEAIKEYGYKTIQKWRRSFN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCHHHHHHHHHHCC
VIPPNICGGNNQFIATNDNRYANISTDELPSSESLELTLKRVIPYWNQSIIPHIKKGQTI
CCCCCCCCCCCCEEEECCCEEEECCHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
IIVAHGNSIRAIIKFLNHLNESEIFQINVPTGVPLIYEFDKKANTVQHYYLK
EEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA