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The map label for this gene is sucD [H]

Identifier: 71892112

GI number: 71892112

Start: 408240

End: 409121

Strand: Direct

Name: sucD [H]

Synonym: BPEN_344

Alternate gene names: 71892112

Gene position: 408240-409121 (Clockwise)

Preceding gene: 71892111

Following gene: 71892113

Centisome position: 51.57

GC content: 34.47

Gene sequence:

>882_bases
ATGTCAATTTTAGTTAACAAAGATACAAAAATAATTTGTCAAGGATTTACTGGTAAACACGCCAGTTTTCATTCTCAACA
AGCATTAAATTATGGTACTAAAATAGTAGGCGGAGTTACCCCTGGAAAAGGAGGAAGTATCCATCTTGGATTGCCAATAT
TTAACACTGTTGGTGAGGCAATAAATAACACCAGTGCGACGACTTCTATTATTTATGTACCCGCTCCTTTCTGTAAGGAC
GCAATTTTAGAATCAATTCATGCCGGTATTAAATTAATTGTTTGTATTACCGAAGGAATTCCAATATTGGATATGTTATT
AATAAAACAACAATTAAAAAAACATAACACATGTATGATTGGACCAAATTGTCCAGGAATCATTACTCCAGGCCAGTGTA
AACTTGGAATTATGCCAAGTGATATCCATAACCCAGGTTGCGTAGGAATTATATCCAGATCAGGTACCTTAACATATGAA
GTAGTAAAACAAACAACTGACCTTGGATTGGGTCAGTCCACATGCGTCGGCATTGGAGGTGACCCGATACTTGGTTCTGA
TTTTATTGATATATTATCATTATTTGAACAAGATCCTCAAACATCATTAATGGTAATGATTGGTGAAATAGGAGGTAGAT
CTGAAGAAAAAGCAGCAAAATATATTAATAAATATATTAAGAAACCAGTGATTGCATATATTGCTGGAACTACCGCTCCT
AAAGGGAAACGTATGGGGCACGCAGGTGCTATTATTTCTGGCATTGGCAGTACTGCTCATGAAAAATACGAGATTTTATC
GCAATCAGGAGTACATATCGTAAATAATTTTATTAACATTGGCCAATTTATTAAATCTATTGATAAACAACAATACACAT
AA

Upstream 100 bases:

>100_bases
TTAGGTTCTAATCGATTAATTAATAGCAAACTTAATATTATTGTTACCGATAATTTAATTTATGCAATTCAACAAAGTGT
AACTGCGGTGAACTTAAAAA

Downstream 100 bases:

>100_bases
TATATGTAAATAACATATACGCATATGCCATGTACATTACTAATAATATTAGTAGCTATATTACCTATATTATGGTAATA
GTAAGTGAGACATGATTAAT

Product: succinyl-CoA synthetase, alpha chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILVNKDTKIICQGFTGKHASFHSQQALNYGTKIVGGVTPGKGGSIHLGLPIFNTVGEAINNTSATTSIIYVPAPFCKD
AILESIHAGIKLIVCITEGIPILDMLLIKQQLKKHNTCMIGPNCPGIITPGQCKLGIMPSDIHNPGCVGIISRSGTLTYE
VVKQTTDLGLGQSTCVGIGGDPILGSDFIDILSLFEQDPQTSLMVMIGEIGGRSEEKAAKYINKYIKKPVIAYIAGTTAP
KGKRMGHAGAIISGIGSTAHEKYEILSQSGVHIVNNFINIGQFIKSIDKQQYT

Sequences:

>Translated_293_residues
MSILVNKDTKIICQGFTGKHASFHSQQALNYGTKIVGGVTPGKGGSIHLGLPIFNTVGEAINNTSATTSIIYVPAPFCKD
AILESIHAGIKLIVCITEGIPILDMLLIKQQLKKHNTCMIGPNCPGIITPGQCKLGIMPSDIHNPGCVGIISRSGTLTYE
VVKQTTDLGLGQSTCVGIGGDPILGSDFIDILSLFEQDPQTSLMVMIGEIGGRSEEKAAKYINKYIKKPVIAYIAGTTAP
KGKRMGHAGAIISGIGSTAHEKYEILSQSGVHIVNNFINIGQFIKSIDKQQYT
>Mature_292_residues
SILVNKDTKIICQGFTGKHASFHSQQALNYGTKIVGGVTPGKGGSIHLGLPIFNTVGEAINNTSATTSIIYVPAPFCKDA
ILESIHAGIKLIVCITEGIPILDMLLIKQQLKKHNTCMIGPNCPGIITPGQCKLGIMPSDIHNPGCVGIISRSGTLTYEV
VKQTTDLGLGQSTCVGIGGDPILGSDFIDILSLFEQDPQTSLMVMIGEIGGRSEEKAAKYINKYIKKPVIAYIAGTTAPK
GKRMGHAGAIISGIGSTAHEKYEILSQSGVHIVNNFINIGQFIKSIDKQQYT

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=57.6271186440678, Blast_Score=293, Evalue=1e-79,
Organism=Homo sapiens, GI38569423, Length=290, Percent_Identity=30.6896551724138, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI38569421, Length=290, Percent_Identity=30.6896551724138, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=67.4740484429066, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=55.0877192982456, Blast_Score=305, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17553126, Length=285, Percent_Identity=52.9824561403509, Blast_Score=293, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI17557344, Length=258, Percent_Identity=28.6821705426357, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=27.5193798449612, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324716, Length=290, Percent_Identity=50, Blast_Score=270, Evalue=1e-73,
Organism=Drosophila melanogaster, GI21356559, Length=285, Percent_Identity=51.9298245614035, Blast_Score=301, Evalue=4e-82,
Organism=Drosophila melanogaster, GI28574296, Length=286, Percent_Identity=54.8951048951049, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI281363477, Length=256, Percent_Identity=28.515625, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363475, Length=256, Percent_Identity=28.515625, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363473, Length=256, Percent_Identity=28.515625, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31121; Mature: 30990

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVNKDTKIICQGFTGKHASFHSQQALNYGTKIVGGVTPGKGGSIHLGLPIFNTVGEA
CEEEEECCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHHHHHHH
INNTSATTSIIYVPAPFCKDAILESIHAGIKLIVCITEGIPILDMLLIKQQLKKHNTCMI
HCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEE
GPNCPGIITPGQCKLGIMPSDIHNPGCVGIISRSGTLTYEVVKQTTDLGLGQSTCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPILGSDFIDILSLFEQDPQTSLMVMIGEIGGRSEEKAAKYINKYIKKPVIAYIAGTTAP
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
KGKRMGHAGAIISGIGSTAHEKYEILSQSGVHIVNNFINIGQFIKSIDKQQYT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILVNKDTKIICQGFTGKHASFHSQQALNYGTKIVGGVTPGKGGSIHLGLPIFNTVGEA
EEEEECCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHHHHHHH
INNTSATTSIIYVPAPFCKDAILESIHAGIKLIVCITEGIPILDMLLIKQQLKKHNTCMI
HCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEE
GPNCPGIITPGQCKLGIMPSDIHNPGCVGIISRSGTLTYEVVKQTTDLGLGQSTCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPILGSDFIDILSLFEQDPQTSLMVMIGEIGGRSEEKAAKYINKYIKKPVIAYIAGTTAP
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
KGKRMGHAGAIISGIGSTAHEKYEILSQSGVHIVNNFINIGQFIKSIDKQQYT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]