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The map label for this gene is cyoB [H]

Identifier: 71892025

GI number: 71892025

Start: 282269

End: 284230

Strand: Reverse

Name: cyoB [H]

Synonym: BPEN_251

Alternate gene names: 71892025

Gene position: 284230-282269 (Counterclockwise)

Preceding gene: 71892026

Following gene: 71892024

Centisome position: 35.9

GC content: 33.08

Gene sequence:

>1962_bases
ATGTTTGGAAAATTAACAACACATTCTATTCCATATGAAGATCCAGTTATTATGTCGACAGTTATTATCATTCTTTTCAT
TGGAATAATTCTTTCTGGTATCATTACATATTACAATAAATGGCGATATCTTTGGAATGAGTGGTTTACTTCTGTAGATC
ATAAAAAAATTGGGATTATGTATATTATAGTCTCATGTATTATGTTTGTACGTGGTTTTGCCGATGCCATCATGATGAGA
GCGCAACAAGCTTTATCTTCTTCTGGATCGTATGAATTTCTTTCAGCCTATCATTACAACCAAGTAATTACTGCTCATGG
CGTAATCATGATCATATTTATGGCTACTCCTTTCGTAATAGGATTAATGAACTTGGTAGTTCCATTACAAATTGGAGCAC
GAGATGTTGCTTTTCCTTTTTTAAACTCATTGAGTTTTTGGTTGTTTATGGTGGGTGTAATTTTGATGAATCTTTCCTTA
GGAATAGGAGAATTTGCGCAAACAGGATGGTCAGGTTACCCGCCATTATCAAGCAAAGAATATAGTCCTGGTGTTGGTGT
CGATTATTGGATATGGAGTATACAAATTTCTGGAATAGGAACTACTTTGACTGGTATAAATTTTTTCACTACAATTTTAT
ACATGCGAGCTCCAGGATTGTCGATGATGAAAATGCCAGTTTTTACTTGGACTGCTTTATGTACAAATACATTAATCATT
GCGGCTTTTCCAATTTTGACTATTACTATCGCTTTATTAACACTAGACCGTTACCTAGGAACCCATTTTTTTACTAATGA
TTTAGGCGGAAATATGATGATGTATATCAATTTATTTTGGGCTTGGGGTCATCCAGAAGTATATATTTTAGTGTTGCCCG
TATTTGGTGTATTTTCAGAAATTGTTTCCACTTTTTCACAAAAGAAATTGTTTGGATATACTTCATTAATATGGGCTACT
ATAGCTATTACTGTGTTATCTTTTTGTGTATGGTTACACCATTTTTTTACTATGGGTGCGGGTGCTAACGTTAATGCATT
TTTCGGTATTATGACCATGATAATTGCCATTCCAACTGGAGTAAAGGTATTTAACTGGTTATTCACTATGTATCGAGGAA
AAATTGTTTTTTCCTCCCCAATGATGTGGACTATTGGATTTATCATTACATTTGCCATAGGAGGAATGACTGGGGTGTTA
TTGTCTGTGCCAGGGGCTGATTTTGTATTGCATAACAGTTTATTTTTAATCGCACATTTTCATAATGTTATTATTGGAGG
AGTATTGTTCGGTTGTTTTGCAGGAACCACCTATTGGTTTCCTAAGGCTTTTGGTTATGTTTTAAATGAAAAATGGGGGA
AACGAGCTTTTTGGTTTTGGATTATTGGATTTTATATAGCGTTTATGCCGTTATATATTTTAGGGTTTATGGGTATGACT
CGTCGATTAAGCCAACACATTGATCCAATATTTTCATCGATGTTAATAACCGCATCAATGGGTACTATATTGATTGGATT
AGGTATTATGTGTCAATGTATCCAAATAATAGTCAGTATTGTAAATCGCGATAAACATAAAGATATAAATGGAAATCCAT
GGAATGGATCTACTTTAGAATGGGCTGTTTCTTCTCCCCCGCCATTTTATAATTTTGCAATTATTCCTATAATAAACAAT
GATCGTGATGTTTTTTGGTATGTACAAAATAATAGAAACATATACTCTTGTCCTGATCAATTTCAATCCATACATATGCC
CAAGAATACGTATTCTGGCATTGTTATATCTTTTTTCGCTTTAACATTTGGATTTGGTATGATTTGGTATATATGGTGGC
TCGTTGTTTTTAGTATGTTTGGAATAATAGCAACTTGGATTCTTCATACATTTAATGATGATACAGAATATTACGTACCA
GTAGAGAAAATTAAAGAAATTGAATGTGTTAATAATGTATAA

Upstream 100 bases:

>100_bases
ACATCAAAAGAAAGAATATTTTTAGCTATAATTCATGTTTCCTTAATATAAAGCATGATTGTTTTGGGAAATGTTGCAAA
TATATGAGGATAATAAAATA

Downstream 100 bases:

>100_bases
ACATAATAATTTAAATATAAAGACAATATTTGGTTTCTGGTTATACATAATGAGTGATTGTATTCTATTCGCAAGTTTAT
TTGCAATATACTCTGTGTTA

Product: cytochrome o ubiquinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MFGKLTTHSIPYEDPVIMSTVIIILFIGIILSGIITYYNKWRYLWNEWFTSVDHKKIGIMYIIVSCIMFVRGFADAIMMR
AQQALSSSGSYEFLSAYHYNQVITAHGVIMIIFMATPFVIGLMNLVVPLQIGARDVAFPFLNSLSFWLFMVGVILMNLSL
GIGEFAQTGWSGYPPLSSKEYSPGVGVDYWIWSIQISGIGTTLTGINFFTTILYMRAPGLSMMKMPVFTWTALCTNTLII
AAFPILTITIALLTLDRYLGTHFFTNDLGGNMMMYINLFWAWGHPEVYILVLPVFGVFSEIVSTFSQKKLFGYTSLIWAT
IAITVLSFCVWLHHFFTMGAGANVNAFFGIMTMIIAIPTGVKVFNWLFTMYRGKIVFSSPMMWTIGFIITFAIGGMTGVL
LSVPGADFVLHNSLFLIAHFHNVIIGGVLFGCFAGTTYWFPKAFGYVLNEKWGKRAFWFWIIGFYIAFMPLYILGFMGMT
RRLSQHIDPIFSSMLITASMGTILIGLGIMCQCIQIIVSIVNRDKHKDINGNPWNGSTLEWAVSSPPPFYNFAIIPIINN
DRDVFWYVQNNRNIYSCPDQFQSIHMPKNTYSGIVISFFALTFGFGMIWYIWWLVVFSMFGIIATWILHTFNDDTEYYVP
VEKIKEIECVNNV

Sequences:

>Translated_653_residues
MFGKLTTHSIPYEDPVIMSTVIIILFIGIILSGIITYYNKWRYLWNEWFTSVDHKKIGIMYIIVSCIMFVRGFADAIMMR
AQQALSSSGSYEFLSAYHYNQVITAHGVIMIIFMATPFVIGLMNLVVPLQIGARDVAFPFLNSLSFWLFMVGVILMNLSL
GIGEFAQTGWSGYPPLSSKEYSPGVGVDYWIWSIQISGIGTTLTGINFFTTILYMRAPGLSMMKMPVFTWTALCTNTLII
AAFPILTITIALLTLDRYLGTHFFTNDLGGNMMMYINLFWAWGHPEVYILVLPVFGVFSEIVSTFSQKKLFGYTSLIWAT
IAITVLSFCVWLHHFFTMGAGANVNAFFGIMTMIIAIPTGVKVFNWLFTMYRGKIVFSSPMMWTIGFIITFAIGGMTGVL
LSVPGADFVLHNSLFLIAHFHNVIIGGVLFGCFAGTTYWFPKAFGYVLNEKWGKRAFWFWIIGFYIAFMPLYILGFMGMT
RRLSQHIDPIFSSMLITASMGTILIGLGIMCQCIQIIVSIVNRDKHKDINGNPWNGSTLEWAVSSPPPFYNFAIIPIINN
DRDVFWYVQNNRNIYSCPDQFQSIHMPKNTYSGIVISFFALTFGFGMIWYIWWLVVFSMFGIIATWILHTFNDDTEYYVP
VEKIKEIECVNNV
>Mature_653_residues
MFGKLTTHSIPYEDPVIMSTVIIILFIGIILSGIITYYNKWRYLWNEWFTSVDHKKIGIMYIIVSCIMFVRGFADAIMMR
AQQALSSSGSYEFLSAYHYNQVITAHGVIMIIFMATPFVIGLMNLVVPLQIGARDVAFPFLNSLSFWLFMVGVILMNLSL
GIGEFAQTGWSGYPPLSSKEYSPGVGVDYWIWSIQISGIGTTLTGINFFTTILYMRAPGLSMMKMPVFTWTALCTNTLII
AAFPILTITIALLTLDRYLGTHFFTNDLGGNMMMYINLFWAWGHPEVYILVLPVFGVFSEIVSTFSQKKLFGYTSLIWAT
IAITVLSFCVWLHHFFTMGAGANVNAFFGIMTMIIAIPTGVKVFNWLFTMYRGKIVFSSPMMWTIGFIITFAIGGMTGVL
LSVPGADFVLHNSLFLIAHFHNVIIGGVLFGCFAGTTYWFPKAFGYVLNEKWGKRAFWFWIIGFYIAFMPLYILGFMGMT
RRLSQHIDPIFSSMLITASMGTILIGLGIMCQCIQIIVSIVNRDKHKDINGNPWNGSTLEWAVSSPPPFYNFAIIPIINN
DRDVFWYVQNNRNIYSCPDQFQSIHMPKNTYSGIVISFFALTFGFGMIWYIWWLVVFSMFGIIATWILHTFNDDTEYYVP
VEKIKEIECVNNV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=39.2156862745098, Blast_Score=339, Evalue=5e-93,
Organism=Escherichia coli, GI1786634, Length=648, Percent_Identity=71.7592592592593, Blast_Score=997, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=527, Percent_Identity=35.8633776091082, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=39.3188854489164, Blast_Score=233, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=31.2, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74146; Mature: 74146

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLTTHSIPYEDPVIMSTVIIILFIGIILSGIITYYNKWRYLWNEWFTSVDHKKIGIM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
YIIVSCIMFVRGFADAIMMRAQQALSSSGSYEFLSAYHYNQVITAHGVIMIIFMATPFVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFLNSLSFWLFMVGVILMNLSLGIGEFAQTGWSGYPPLSSKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
YSPGVGVDYWIWSIQISGIGTTLTGINFFTTILYMRAPGLSMMKMPVFTWTALCTNTLII
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAFPILTITIALLTLDRYLGTHFFTNDLGGNMMMYINLFWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEHHHHHHHHHH
IVSTFSQKKLFGYTSLIWATIAITVLSFCVWLHHFFTMGAGANVNAFFGIMTMIIAIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
VKVFNWLFTMYRGKIVFSSPMMWTIGFIITFAIGGMTGVLLSVPGADFVLHNSLFLIAHF
HHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHCCHHHHHHH
HNVIIGGVLFGCFAGTTYWFPKAFGYVLNEKWGKRAFWFWIIGFYIAFMPLYILGFMGMT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQHIDPIFSSMLITASMGTILIGLGIMCQCIQIIVSIVNRDKHKDINGNPWNGSTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
WAVSSPPPFYNFAIIPIINNDRDVFWYVQNNRNIYSCPDQFQSIHMPKNTYSGIVISFFA
EEECCCCCCCCEEEEEEEECCCEEEEEEECCCEEEECCHHHHHCCCCCCCHHHHHHHHHH
LTFGFGMIWYIWWLVVFSMFGIIATWILHTFNDDTEYYVPVEKIKEIECVNNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MFGKLTTHSIPYEDPVIMSTVIIILFIGIILSGIITYYNKWRYLWNEWFTSVDHKKIGIM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
YIIVSCIMFVRGFADAIMMRAQQALSSSGSYEFLSAYHYNQVITAHGVIMIIFMATPFVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFLNSLSFWLFMVGVILMNLSLGIGEFAQTGWSGYPPLSSKE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
YSPGVGVDYWIWSIQISGIGTTLTGINFFTTILYMRAPGLSMMKMPVFTWTALCTNTLII
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAFPILTITIALLTLDRYLGTHFFTNDLGGNMMMYINLFWAWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEHHHHHHHHHH
IVSTFSQKKLFGYTSLIWATIAITVLSFCVWLHHFFTMGAGANVNAFFGIMTMIIAIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
VKVFNWLFTMYRGKIVFSSPMMWTIGFIITFAIGGMTGVLLSVPGADFVLHNSLFLIAHF
HHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHCCHHHHHHH
HNVIIGGVLFGCFAGTTYWFPKAFGYVLNEKWGKRAFWFWIIGFYIAFMPLYILGFMGMT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQHIDPIFSSMLITASMGTILIGLGIMCQCIQIIVSIVNRDKHKDINGNPWNGSTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
WAVSSPPPFYNFAIIPIINNDRDVFWYVQNNRNIYSCPDQFQSIHMPKNTYSGIVISFFA
EEECCCCCCCCEEEEEEEECCCEEEEEEECCCEEEECCHHHHHCCCCCCCHHHHHHHHHH
LTFGFGMIWYIWWLVVFSMFGIIATWILHTFNDDTEYYVPVEKIKEIECVNNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]