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The map label for this gene is ddlA1-C [H]

Identifier: 68535999

GI number: 68535999

Start: 1099491

End: 1100099

Strand: Direct

Name: ddlA1-C [H]

Synonym: jk0922

Alternate gene names: 68535999

Gene position: 1099491-1100099 (Clockwise)

Preceding gene: 68535998

Following gene: 68536000

Centisome position: 44.65

GC content: 57.47

Gene sequence:

>609_bases
GTGGCGAGGAGCTTATTCTCGCCGAAAAACCGCGAGCTCACCGAGGATGAACAACAGCGCCTCGGCCTGCCCGTTTTCGT
TAAGCCTGCCCGCAGAGGCTCCTCCATCGGCATCTCCAAGGTTGACTCATGGGAAGCTTTTGCGCAGGCTGTCGAGATCG
CTTTTGATCACGATAACAAGATGATCGTTGAATCAATGATCCACGGCCGCGAAGTCGAGTGTGGTGTACTGCAATACCCC
GAAGGCTCCGTCATCGCCTCCGCGCCCGCCATGTTGGAGGGGACTGAAGACGGTGACGAGGGCTTCTATGGTTTCGACGC
CAAGTATCTCGATAACACCGTCACCCCTAGTATTCCCGCCCCCATCGGCGAAGAGGCTACCGCGGAGGTCCGTCGCCTCG
CAGTCCGTACCTTTGAGGCGCTGAACTGTGAGGGGTTGGCGCGTGTGGACTTCTTCGTCACGGATAATGGCGAAGTCATC
CTCAACGAAATCAACACCCTTCCGGGATTCACCCCGATCTCCATGTACCCGCAGATGTTTATCGCAGGTGGCATGGAATA
CCCGCAGCTACTGGATATCCTGATTGCCCGGGCTCTGGTGCAGGACTAG

Upstream 100 bases:

>100_bases
CTCGCCGGTATTCCATATGTCGGCAATGGTGTGCTTGCTTCAGCAGCAGGCATGGACAAGGAATACACGAAGTGCCTAGC
CAAGCAGGCAGGTGTGCCGT

Downstream 100 bases:

>100_bases
CAAGAATCTCTCAAAAGTTTTTTGCCGTCGAGCTTCAGCGGGCAGCATCCGAAAATCGGTGAGCCATAGGGACGTCTAGG
GGAAAGCCAGGGGGGGGAGC

Product: putative D-alanine-D-alanine ligase (fragment)

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MARSLFSPKNRELTEDEQQRLGLPVFVKPARRGSSIGISKVDSWEAFAQAVEIAFDHDNKMIVESMIHGREVECGVLQYP
EGSVIASAPAMLEGTEDGDEGFYGFDAKYLDNTVTPSIPAPIGEEATAEVRRLAVRTFEALNCEGLARVDFFVTDNGEVI
LNEINTLPGFTPISMYPQMFIAGGMEYPQLLDILIARALVQD

Sequences:

>Translated_202_residues
MARSLFSPKNRELTEDEQQRLGLPVFVKPARRGSSIGISKVDSWEAFAQAVEIAFDHDNKMIVESMIHGREVECGVLQYP
EGSVIASAPAMLEGTEDGDEGFYGFDAKYLDNTVTPSIPAPIGEEATAEVRRLAVRTFEALNCEGLARVDFFVTDNGEVI
LNEINTLPGFTPISMYPQMFIAGGMEYPQLLDILIARALVQD
>Mature_201_residues
ARSLFSPKNRELTEDEQQRLGLPVFVKPARRGSSIGISKVDSWEAFAQAVEIAFDHDNKMIVESMIHGREVECGVLQYPE
GSVIASAPAMLEGTEDGDEGFYGFDAKYLDNTVTPSIPAPIGEEATAEVRRLAVRTFEALNCEGLARVDFFVTDNGEVIL
NEINTLPGFTPISMYPQMFIAGGMEYPQLLDILIARALVQD

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=185, Percent_Identity=47.5675675675676, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1786280, Length=175, Percent_Identity=33.7142857142857, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 22234; Mature: 22103

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS50975 ATP_GRASP ; PS00844 DALA_DALA_LIGASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSLFSPKNRELTEDEQQRLGLPVFVKPARRGSSIGISKVDSWEAFAQAVEIAFDHDNK
CCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
MIVESMIHGREVECGVLQYPEGSVIASAPAMLEGTEDGDEGFYGFDAKYLDNTVTPSIPA
HHHHHHHCCCCCCCCEEECCCCCEEECCCCEECCCCCCCCCEECCCHHHHCCCCCCCCCC
PIGEEATAEVRRLAVRTFEALNCEGLARVDFFVTDNGEVILNEINTLPGFTPISMYPQMF
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEHHCCCCCCCHHHHHHHH
IAGGMEYPQLLDILIARALVQD
HHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARSLFSPKNRELTEDEQQRLGLPVFVKPARRGSSIGISKVDSWEAFAQAVEIAFDHDNK
CCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
MIVESMIHGREVECGVLQYPEGSVIASAPAMLEGTEDGDEGFYGFDAKYLDNTVTPSIPA
HHHHHHHCCCCCCCCEEECCCCCEEECCCCEECCCCCCCCCEECCCHHHHCCCCCCCCCC
PIGEEATAEVRRLAVRTFEALNCEGLARVDFFVTDNGEVILNEINTLPGFTPISMYPQMF
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEHHCCCCCCCHHHHHHHH
IAGGMEYPQLLDILIARALVQD
HHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA