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The map label for this gene is ddlA1-N [H]

Identifier: 68535998

GI number: 68535998

Start: 1098959

End: 1099540

Strand: Direct

Name: ddlA1-N [H]

Synonym: jk0921

Alternate gene names: 68535998

Gene position: 1098959-1099540 (Clockwise)

Preceding gene: 68535997

Following gene: 68535999

Centisome position: 44.63

GC content: 59.11

Gene sequence:

>582_bases
ATGAATACACCAGCAGCCGATAACGCTTCCGTACGCTCTACTGCCACTGATGTTTCTGCAGAGCACCGCATTAAAGTCGC
GGTTCTTTACGGAGGCCAGTCCAGTGAGCATTCCGTTTCCTGCATCTCCGCAGGCGCGATCATGGATCACCTCGACCCAG
AACGCTACGAGGTCATCCCCGTGGGAATCACCCCTCAAGGCGCGTGGGTCCCGGGTACCGTTGATACCTCCGAGCTGCGC
GCCGACGATCGCGAGATGCCTTCCGTCCGCGATCGGGGTGAACACATTCAGCTCGTGCTTGGCGCCCAAACAGGAGAACT
GCGCTACGTCTCCGGGGTACACGCCGGCCGCACGTACGCGCACGTCGATGTCATTTTCCCCGTCCTCCACGGTCAAAATG
GTGAGGACGGCACCATCCAGGGTCTGTTTGAGCTCGCCGGTATTCCATATGTCGGCAATGGTGTGCTTGCTTCAGCAGCA
GGCATGGACAAGGAATACACGAAGTGCCTAGCCAAGCAGGCAGGTGTGCCGTGTGGCGAGGAGCTTATTCTCGCCGAAAA
ACCGCGAGCTCACCGAGGATGA

Upstream 100 bases:

>100_bases
CGTGTGCCACCGTGGCGCACCGGTGGATGAGATGCTGCAGCGGTTATTGGGCCGCAGCCGGAAATCGGAGTGACGTTGCC
GAGCGCTACACTGTGAAGCG

Downstream 100 bases:

>100_bases
ACAACAGCGCCTCGGCCTGCCCGTTTTCGTTAAGCCTGCCCGCAGAGGCTCCTCCATCGGCATCTCCAAGGTTGACTCAT
GGGAAGCTTTTGCGCAGGCT

Product: putative D-alanine-D-alanine ligase (fragment)

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNTPAADNASVRSTATDVSAEHRIKVAVLYGGQSSEHSVSCISAGAIMDHLDPERYEVIPVGITPQGAWVPGTVDTSELR
ADDREMPSVRDRGEHIQLVLGAQTGELRYVSGVHAGRTYAHVDVIFPVLHGQNGEDGTIQGLFELAGIPYVGNGVLASAA
GMDKEYTKCLAKQAGVPCGEELILAEKPRAHRG

Sequences:

>Translated_193_residues
MNTPAADNASVRSTATDVSAEHRIKVAVLYGGQSSEHSVSCISAGAIMDHLDPERYEVIPVGITPQGAWVPGTVDTSELR
ADDREMPSVRDRGEHIQLVLGAQTGELRYVSGVHAGRTYAHVDVIFPVLHGQNGEDGTIQGLFELAGIPYVGNGVLASAA
GMDKEYTKCLAKQAGVPCGEELILAEKPRAHRG
>Mature_193_residues
MNTPAADNASVRSTATDVSAEHRIKVAVLYGGQSSEHSVSCISAGAIMDHLDPERYEVIPVGITPQGAWVPGTVDTSELR
ADDREMPSVRDRGEHIQLVLGAQTGELRYVSGVHAGRTYAHVDVIFPVLHGQNGEDGTIQGLFELAGIPYVGNGVLASAA
GMDKEYTKCLAKQAGVPCGEELILAEKPRAHRG

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=170, Percent_Identity=38.2352941176471, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786280, Length=154, Percent_Identity=33.1168831168831, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 20456; Mature: 20456

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00843 DALA_DALA_LIGASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPAADNASVRSTATDVSAEHRIKVAVLYGGQSSEHSVSCISAGAIMDHLDPERYEVIP
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHCCCCCCEEEEE
VGITPQGAWVPGTVDTSELRADDREMPSVRDRGEHIQLVLGAQTGELRYVSGVHAGRTYA
ECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEE
HVDVIFPVLHGQNGEDGTIQGLFELAGIPYVGNGVLASAAGMDKEYTKCLAKQAGVPCGE
EEEEEEEEEECCCCCCCHHHHHHHHCCCCEECCCEEECCCCCCHHHHHHHHHHCCCCCCC
ELILAEKPRAHRG
EEEEECCCCCCCC
>Mature Secondary Structure
MNTPAADNASVRSTATDVSAEHRIKVAVLYGGQSSEHSVSCISAGAIMDHLDPERYEVIP
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHCCCCCCEEEEE
VGITPQGAWVPGTVDTSELRADDREMPSVRDRGEHIQLVLGAQTGELRYVSGVHAGRTYA
ECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEE
HVDVIFPVLHGQNGEDGTIQGLFELAGIPYVGNGVLASAAGMDKEYTKCLAKQAGVPCGE
EEEEEEEEEECCCCCCCHHHHHHHHCCCCEECCCEEECCCCCCHHHHHHHHHHCCCCCCC
ELILAEKPRAHRG
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA