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The map label for this gene is argD [H]

Identifier: 68535919

GI number: 68535919

Start: 1005605

End: 1006819

Strand: Direct

Name: argD [H]

Synonym: jk0844

Alternate gene names: 68535919

Gene position: 1005605-1006819 (Clockwise)

Preceding gene: 68535918

Following gene: 68535920

Centisome position: 40.84

GC content: 65.76

Gene sequence:

>1215_bases
ATGACCCAGAACCTAGAGAACGCAACCAACGACTGGCAGGGCCACTGGAACGCCGCGCTGTTCGAAACCTACGGCACCCC
GCCGCGCGAGCTGGTTTCTGGCCGTGGCACCATCGTCACCGACGCAGAAGGCAACGAGTACCTCGACCTGCTGTCCGGCA
TCGCCGTGAATGCTCTGGGGCACGCTCACCCTGCCATTGTTGACGCCGTGACGAATCAGATCGCCACGCTCAGCCACACG
TCTAACCTCTTCGCCCACCCGCAGGTGATCAAACTCGCCGAGCGGCTGAAAGGCCTGCTGGGGGTGCAGAGTGGGGAGGC
AGCCGAGGCGATGGCCGGTGCCCGCGTGTTCTTCTCCAACTCCGGCGCCGAGGCCAACGAGGCCGCCTTCAAGATCGCCC
GTGCCACCGGTAAGACCAAGATCCTGGCCGCCGAGCGTGGCTTCCACGGCCGCACCATGGGTGCCCTCGCTCTGACCGGC
CAGCCGGATAAGCAGGAGGCCTTCAAGCCCCTGCCCGGCGGCGTGGAGTACTACCCCTACGGCGACATCAAAGCCCTGCG
GGAGATGGCAGACGACGACACTGCCGCGATCTTCCTGGAGTCCATCCAGGGCGAAACCGGCGTGATCCCCGCCCCGGACG
GCTTCCTCGCCGCCGTGCGGGAGTTGTGTGATGCCCACGACATCCTCATGGTCGTTGACGAGGTACAGGCCGGCATGGGG
CGCACCGGCCAGTGGTTCGGATTCCAGCACGAGGCCGGGGTGCTGCCGGACGTCATCACTATGGCCAAGGGACTGGGCGG
TGGCCTGCCGATCGGCGCCACCCTCGCCCTGCCGAAGGCACAGCTGCTGGCCAAGGGGATGCACGGAACCACCTTCGGCG
GAAACCCCGTCGTCTGCGCGGCCGCGAACGCCGTCATCGACACGATCGAAGCCGAGGACCTTCTGGCAAACGTCGCCACC
CAGTCGCAGGCAATCCGCGATGGCCTGGCCGATCACCCCAGCGTGCAGACCATCCGTGGCCGCGGGCTCATGCTGGGCAT
CGTTCTGGATGCGCCCCTTAACCTGGATCCACTGGACTACGGGCTGATCATCAACAAGCCCCAGCCCGATGTGATCCGCC
TGGTTCCGCCGCTGAATATCTCGGCGGATGAGGTGCAGCGGGGCGTCACAAAGATTAGGCAGATGCTGGACGACAACCGC
GCGCAGAACCAGTAA

Upstream 100 bases:

>100_bases
TCTTGGAGCTGATGACCACCGGCGGTATCGGCACCATGATCTGCCCCGCGGGCTGGGAAGACATTGCCAGCCCCGACATC
AACTATCGGGAGGACCTCCC

Downstream 100 bases:

>100_bases
CCACAGAAAGAACGGAAGACACCACATGACAAACCTGCACCTGCAGAAAAAGGGGCCGCTGCGCCACATGCTGGCCGACG
ACGACCTCACCCCGGAAGAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTQNLENATNDWQGHWNAALFETYGTPPRELVSGRGTIVTDAEGNEYLDLLSGIAVNALGHAHPAIVDAVTNQIATLSHT
SNLFAHPQVIKLAERLKGLLGVQSGEAAEAMAGARVFFSNSGAEANEAAFKIARATGKTKILAAERGFHGRTMGALALTG
QPDKQEAFKPLPGGVEYYPYGDIKALREMADDDTAAIFLESIQGETGVIPAPDGFLAAVRELCDAHDILMVVDEVQAGMG
RTGQWFGFQHEAGVLPDVITMAKGLGGGLPIGATLALPKAQLLAKGMHGTTFGGNPVVCAAANAVIDTIEAEDLLANVAT
QSQAIRDGLADHPSVQTIRGRGLMLGIVLDAPLNLDPLDYGLIINKPQPDVIRLVPPLNISADEVQRGVTKIRQMLDDNR
AQNQ

Sequences:

>Translated_404_residues
MTQNLENATNDWQGHWNAALFETYGTPPRELVSGRGTIVTDAEGNEYLDLLSGIAVNALGHAHPAIVDAVTNQIATLSHT
SNLFAHPQVIKLAERLKGLLGVQSGEAAEAMAGARVFFSNSGAEANEAAFKIARATGKTKILAAERGFHGRTMGALALTG
QPDKQEAFKPLPGGVEYYPYGDIKALREMADDDTAAIFLESIQGETGVIPAPDGFLAAVRELCDAHDILMVVDEVQAGMG
RTGQWFGFQHEAGVLPDVITMAKGLGGGLPIGATLALPKAQLLAKGMHGTTFGGNPVVCAAANAVIDTIEAEDLLANVAT
QSQAIRDGLADHPSVQTIRGRGLMLGIVLDAPLNLDPLDYGLIINKPQPDVIRLVPPLNISADEVQRGVTKIRQMLDDNR
AQNQ
>Mature_403_residues
TQNLENATNDWQGHWNAALFETYGTPPRELVSGRGTIVTDAEGNEYLDLLSGIAVNALGHAHPAIVDAVTNQIATLSHTS
NLFAHPQVIKLAERLKGLLGVQSGEAAEAMAGARVFFSNSGAEANEAAFKIARATGKTKILAAERGFHGRTMGALALTGQ
PDKQEAFKPLPGGVEYYPYGDIKALREMADDDTAAIFLESIQGETGVIPAPDGFLAAVRELCDAHDILMVVDEVQAGMGR
TGQWFGFQHEAGVLPDVITMAKGLGGGLPIGATLALPKAQLLAKGMHGTTFGGNPVVCAAANAVIDTIEAEDLLANVATQ
SQAIRDGLADHPSVQTIRGRGLMLGIVLDAPLNLDPLDYGLIINKPQPDVIRLVPPLNISADEVQRGVTKIRQMLDDNRA
QNQ

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=394, Percent_Identity=34.7715736040609, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=36.9127516778523, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=32.5842696629214, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=27.6190476190476, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=27.5294117647059, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=28.051948051948, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=26.6666666666667, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI188536080, Length=379, Percent_Identity=27.4406332453826, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI38679950, Length=379, Percent_Identity=27.4406332453826, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI38679946, Length=379, Percent_Identity=27.4406332453826, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=38.0102040816327, Blast_Score=267, Evalue=8e-73,
Organism=Escherichia coli, GI1789759, Length=380, Percent_Identity=39.2105263157895, Blast_Score=264, Evalue=9e-72,
Organism=Escherichia coli, GI145693181, Length=400, Percent_Identity=36.25, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=35.4679802955665, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789016, Length=400, Percent_Identity=35, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=28.4705882352941, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=28.4431137724551, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=31.5, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI25144274, Length=392, Percent_Identity=28.3163265306122, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=29.6803652968037, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=27.5862068965517, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71981843, Length=197, Percent_Identity=26.3959390862944, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17541228, Length=335, Percent_Identity=24.7761194029851, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=34.9246231155779, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323470, Length=431, Percent_Identity=32.9466357308585, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324386, Length=427, Percent_Identity=24.824355971897, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357415, Length=392, Percent_Identity=33.6734693877551, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI161085790, Length=424, Percent_Identity=31.3679245283019, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=31.1475409836066, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=28.5714285714286, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366494, Length=364, Percent_Identity=25.8241758241758, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667139, Length=364, Percent_Identity=25.8241758241758, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667143, Length=364, Percent_Identity=25.8241758241758, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42700; Mature: 42569

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNLENATNDWQGHWNAALFETYGTPPRELVSGRGTIVTDAEGNEYLDLLSGIAVNALG
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHC
HAHPAIVDAVTNQIATLSHTSNLFAHPQVIKLAERLKGLLGVQSGEAAEAMAGARVFFSN
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEC
SGAEANEAAFKIARATGKTKILAAERGFHGRTMGALALTGQPDKQEAFKPLPGGVEYYPY
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCC
GDIKALREMADDDTAAIFLESIQGETGVIPAPDGFLAAVRELCDAHDILMVVDEVQAGMG
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCC
RTGQWFGFQHEAGVLPDVITMAKGLGGGLPIGATLALPKAQLLAKGMHGTTFGGNPVVCA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCHHHHHHCCCCCCCCCCCCEEEE
AANAVIDTIEAEDLLANVATQSQAIRDGLADHPSVQTIRGRGLMLGIVLDAPLNLDPLDY
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCC
GLIINKPQPDVIRLVPPLNISADEVQRGVTKIRQMLDDNRAQNQ
CEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQNLENATNDWQGHWNAALFETYGTPPRELVSGRGTIVTDAEGNEYLDLLSGIAVNALG
CCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHC
HAHPAIVDAVTNQIATLSHTSNLFAHPQVIKLAERLKGLLGVQSGEAAEAMAGARVFFSN
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEC
SGAEANEAAFKIARATGKTKILAAERGFHGRTMGALALTGQPDKQEAFKPLPGGVEYYPY
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCC
GDIKALREMADDDTAAIFLESIQGETGVIPAPDGFLAAVRELCDAHDILMVVDEVQAGMG
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCC
RTGQWFGFQHEAGVLPDVITMAKGLGGGLPIGATLALPKAQLLAKGMHGTTFGGNPVVCA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCHHHHHHCCCCCCCCCCCCEEEE
AANAVIDTIEAEDLLANVATQSQAIRDGLADHPSVQTIRGRGLMLGIVLDAPLNLDPLDY
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCC
GLIINKPQPDVIRLVPPLNISADEVQRGVTKIRQMLDDNRAQNQ
CEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8581175; 12948626 [H]