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The map label for this gene is trpB [H]

Identifier: 68535873

GI number: 68535873

Start: 951210

End: 952499

Strand: Direct

Name: trpB [H]

Synonym: jk0798

Alternate gene names: 68535873

Gene position: 951210-952499 (Clockwise)

Preceding gene: 161986624

Following gene: 68535874

Centisome position: 38.63

GC content: 67.13

Gene sequence:

>1290_bases
GTGACTACCGAGAAGACCTTCAAGAACGCCGACGCGCAAGGCAAGACCCTGCCGACGGTAGGCGAGATCCTGGCGACCGC
CACCCACCACGAGCCCGACGAGCGCGGACACTGGGGTGATTTCGGTGGCCGCTACGTCCCCGAGGCCCTCATGGCCGTGA
TCGAGGAGATCACCGACGCCTGGGCGAAGGCCCGCTCGGACCAGGGGTACCTGGACCAGCTCGACGAGCTGCACCGCACC
TACACCGGCCGCCCGTCGCCGCTGTACTACGCGGCCCGCTTCTCCGAGGCCGTGGGCGCAGAGGTGTGGCTGAAGCGCGA
GGACCTGAACCACACCGGATCTCACAAGATCAACAACGTGCTGGGGCAGGTGCTGCTGGCCAAGCGCATGGGCAAGACTC
GTGTGATCGCGGAGACCGGCGCAGGCCAGCACGGTGTGGCCACGGCGACGGCCTGTGCGCTGCTCGGCATTGATTGCCGG
ATCTACATGGGGGCCGTGGACGCCGAACGGCAGGCCCTCAACATCGCTCGCATGCGCCTGCTCGGTGCCCACGTGGAGGT
AGTGGAGATCGGCTCCCGCACCCTGAAGGACGCCATCAACGAGGCCATGCGCTTCTGGGTTTCCAACGCCGACGACACCT
ACTACTGCTTCGGCACCGCCGCCGGCCCGCACCCATTCCCGCAGATGGTGCGCGACCTGCAGCGCGTGATCGGCGTGGAG
GCGCGCCAGCAGCTGCTGGCCGAAACCGGCAAGCTGCCCGACGCCGTAGTGGCCTGCGTGGGCGGCGGTTCCAACGCGAT
CGGACTGTTCCACCCGTTCATCGAGGACGAAGGCGTGGACATCGTCGGCGCTGAGGCCGCGGGCGACGGTGTAGAGACCG
GTCGCCACGCCGCGCCGATCAACCTGGGGCTGCAGGGCGTGTTCCAGGGGGCCTTCGCCGACCTCATGCAGGACGAGGAC
GGGCAGATTATCGAATCGCACTCCATCTCCGCCGGGTTGGATTACCCGGGCGTGGGGCCGGAGCACTCTAAGCTGCACGC
TGAAGGGCGCGCCCGCTACCTGCCGATCACCGACTCCGAGGCCATGGATGGCTTCAAGCAGCTGACCCTCCTGGAGGGCA
TCATCCCCGCCATCGAGTCCTCCCACGCGGTCGCCGCCGCCATTAAGGTGGCCGCGGAGAAGCCGGGATCCACGCTGATT
GTGAACATTTCCGGCCGCGGCGACAAGGACGTCAACACGGCTGCGAAGTGGTTCGACATGCTGGATCAGAAGAGCGAGAA
GGACGGCTAA

Upstream 100 bases:

>100_bases
CACCGCAGGTAACCCCGCCCAGGCGTGCCGGGACCTCGCCGCAGCGGGAAAACACCCAGCCTGCCCCCAAAAGAATTCCT
AAGCGATAGCATATAAAACT

Downstream 100 bases:

>100_bases
CCCATGACCTCCCGACTTTCTAAGGTTTTCACCGACGCGCGCGCCGAGGGGCGAGCCGCACTCGTGGCCTACTTCCCGGC
CGGCTACCCCACGGTGGCTA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTTEKTFKNADAQGKTLPTVGEILATATHHEPDERGHWGDFGGRYVPEALMAVIEEITDAWAKARSDQGYLDQLDELHRT
YTGRPSPLYYAARFSEAVGAEVWLKREDLNHTGSHKINNVLGQVLLAKRMGKTRVIAETGAGQHGVATATACALLGIDCR
IYMGAVDAERQALNIARMRLLGAHVEVVEIGSRTLKDAINEAMRFWVSNADDTYYCFGTAAGPHPFPQMVRDLQRVIGVE
ARQQLLAETGKLPDAVVACVGGGSNAIGLFHPFIEDEGVDIVGAEAAGDGVETGRHAAPINLGLQGVFQGAFADLMQDED
GQIIESHSISAGLDYPGVGPEHSKLHAEGRARYLPITDSEAMDGFKQLTLLEGIIPAIESSHAVAAAIKVAAEKPGSTLI
VNISGRGDKDVNTAAKWFDMLDQKSEKDG

Sequences:

>Translated_429_residues
MTTEKTFKNADAQGKTLPTVGEILATATHHEPDERGHWGDFGGRYVPEALMAVIEEITDAWAKARSDQGYLDQLDELHRT
YTGRPSPLYYAARFSEAVGAEVWLKREDLNHTGSHKINNVLGQVLLAKRMGKTRVIAETGAGQHGVATATACALLGIDCR
IYMGAVDAERQALNIARMRLLGAHVEVVEIGSRTLKDAINEAMRFWVSNADDTYYCFGTAAGPHPFPQMVRDLQRVIGVE
ARQQLLAETGKLPDAVVACVGGGSNAIGLFHPFIEDEGVDIVGAEAAGDGVETGRHAAPINLGLQGVFQGAFADLMQDED
GQIIESHSISAGLDYPGVGPEHSKLHAEGRARYLPITDSEAMDGFKQLTLLEGIIPAIESSHAVAAAIKVAAEKPGSTLI
VNISGRGDKDVNTAAKWFDMLDQKSEKDG
>Mature_428_residues
TTEKTFKNADAQGKTLPTVGEILATATHHEPDERGHWGDFGGRYVPEALMAVIEEITDAWAKARSDQGYLDQLDELHRTY
TGRPSPLYYAARFSEAVGAEVWLKREDLNHTGSHKINNVLGQVLLAKRMGKTRVIAETGAGQHGVATATACALLGIDCRI
YMGAVDAERQALNIARMRLLGAHVEVVEIGSRTLKDAINEAMRFWVSNADDTYYCFGTAAGPHPFPQMVRDLQRVIGVEA
RQQLLAETGKLPDAVVACVGGGSNAIGLFHPFIEDEGVDIVGAEAAGDGVETGRHAAPINLGLQGVFQGAFADLMQDEDG
QIIESHSISAGLDYPGVGPEHSKLHAEGRARYLPITDSEAMDGFKQLTLLEGIIPAIESSHAVAAAIKVAAEKPGSTLIV
NISGRGDKDVNTAAKWFDMLDQKSEKDG

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=392, Percent_Identity=54.0816326530612, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321412, Length=390, Percent_Identity=56.4102564102564, Blast_Score=443, Evalue=1e-125,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 46063; Mature: 45932

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEKTFKNADAQGKTLPTVGEILATATHHEPDERGHWGDFGGRYVPEALMAVIEEITDA
CCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
WAKARSDQGYLDQLDELHRTYTGRPSPLYYAARFSEAVGAEVWLKREDLNHTGSHKINNV
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHEEECCCCCCCCCHHHHHH
LGQVLLAKRMGKTRVIAETGAGQHGVATATACALLGIDCRIYMGAVDAERQALNIARMRL
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
LGAHVEVVEIGSRTLKDAINEAMRFWVSNADDTYYCFGTAAGPHPFPQMVRDLQRVIGVE
HHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCHH
ARQQLLAETGKLPDAVVACVGGGSNAIGLFHPFIEDEGVDIVGAEAAGDGVETGRHAAPI
HHHHHHHHHCCCCCHHEEEECCCCCCEEHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
NLGLQGVFQGAFADLMQDEDGQIIESHSISAGLDYPGVGPEHSKLHAEGRARYLPITDSE
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHEECCCCEEEECCCCCH
AMDGFKQLTLLEGIIPAIESSHAVAAAIKVAAEKPGSTLIVNISGRGDKDVNTAAKWFDM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
LDQKSEKDG
HHHHCCCCC
>Mature Secondary Structure 
TTEKTFKNADAQGKTLPTVGEILATATHHEPDERGHWGDFGGRYVPEALMAVIEEITDA
CCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
WAKARSDQGYLDQLDELHRTYTGRPSPLYYAARFSEAVGAEVWLKREDLNHTGSHKINNV
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHEEECCCCCCCCCHHHHHH
LGQVLLAKRMGKTRVIAETGAGQHGVATATACALLGIDCRIYMGAVDAERQALNIARMRL
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
LGAHVEVVEIGSRTLKDAINEAMRFWVSNADDTYYCFGTAAGPHPFPQMVRDLQRVIGVE
HHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCHH
ARQQLLAETGKLPDAVVACVGGGSNAIGLFHPFIEDEGVDIVGAEAAGDGVETGRHAAPI
HHHHHHHHHCCCCCHHEEEECCCCCCEEHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
NLGLQGVFQGAFADLMQDEDGQIIESHSISAGLDYPGVGPEHSKLHAEGRARYLPITDSE
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHEECCCCEEEECCCCCH
AMDGFKQLTLLEGIIPAIESSHAVAAAIKVAAEKPGSTLIVNISGRGDKDVNTAAKWFDM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
LDQKSEKDG
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]