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The map label for this gene is cbhA [H]

Identifier: 66766964

GI number: 66766964

Start: 743867

End: 745567

Strand: Reverse

Name: cbhA [H]

Synonym: XC_0626

Alternate gene names: 66766964

Gene position: 745567-743867 (Counterclockwise)

Preceding gene: 66766967

Following gene: 66766963

Centisome position: 14.48

GC content: 61.73

Gene sequence:

>1701_bases
ATGTCATCTTCGACAAACCTCCGACCCTGCGTCACATCCAAGCTCGCCGTTTCGTTGCTGACAGGCGCGCTGCTCGTTCC
CGTTGCCGCATCCGCCCAGAGCCATGTCGACAACCCGTTTGTCGGCGCGAGCGGGTATCTCAATCCCGATTATTCGAAGG
AAGTCAACTCGTCGATCGTCAAGGTCAAGGATGTGCAACTGAAAGCCAAGATGCAGGTCGTCAAGTCCTATCCGACCTCC
GTCTGGCTGGATTCGATCAACGCGATCTATGGCGGCTCGCGCAACGCCGGCCGCCTAAGTCTGCAAGGCCACCTGGATGC
GGCATTGGCGCAGAAAAAGGCCAATACGCCTATCACGGTCGGCTTTGTCATTTACGACATGCCGGGGCGCGACTGCCATG
CGCTGGCCTCCAACGGCGAGCTACCACTGACGCAAGCCGGCTTGCAGCGCTACAAGACCGAATACATCGACGTCATCGCA
TCGACGTTGGCCAATCCGAAATACAAAGATCTTCGGATCGTCAACATCATCGAGCCGGACAGCCTTCCGAATCTTGTCAC
CAATCAAAGCACGCCCGCCTGCGGCCAGGCGGCATCCAGCGGCATTTACGAGGCCGCCATCAAGTACGCGCTCGACAAGC
TCCATGCCACTCCCAATCTTTACAATTACCTGGATATCGGCCATTCCGGCTGGCTGGGGTGGGATAGCAACCGTAGCCCG
GCAATTTCGCTATACACACGGGTCGTGCAGGGAACGGCAGCCGGTTTGGCCAGTGCGGATGGCTTCATCACCAACACCGC
CAATTACACGCCGCTTCATGAGCCGAACCTGCCCAATCCGGACCTGACGATCGGTGGCCAGCCCATTCGCTCGTCCAACT
TCTATCAATGGAACAGTTTCTTCGACGAATCGACCTATGCGGAAGCGCTCTACAACGGCTTCGTCGGCGCGGGTTGGTCC
AGCAAGATCGGCTTTCTGATCGACACCGGTCGCAACGGCTGGGGCGGCAAAGCGCGCCCTGCATCTGCCAGCGGCAATGA
CATCAACACCTACGTGGACTCCGGACGCGTGGACCGTCGCCTCCATCGCGGCAACTGGTGCAATCAGAGTGGTGCGGGGA
TCGGCATGCCGCCGACCGCGGCACCCGGCGGGCATATCCATGCCTTGGTGTGGGGTAAGGGACCGGGCGAATCCGACGGC
GCCAGCAAGTCCATCCTCAACAACCAGGGCAAGGGCTTCGACAGATACTGCGACCCGACCTATACGACGCCGGACGGCAC
GTTGACGGGTGCCTTGCCGAACGCGCCGATCGCCGGTAACTGGTTCCACGCGCAGTTCCTCCAGTTGGTCGCCAACGCGT
ATCCCGCCATCGGCACCTCGACCAAGGCGGCGCTGCAGTCGGCGTCGACCGACGCGGTGCCCGCCAGTCGGCCGACGGCG
ACCAAGGGGTTGACCGCCAATGCAGCGGATGGCGAGGTCAGGCTCAGCTGGTCGCCCGTTGCCGGTGCCACGGGTTACAC
GGTGCAACGTGTCGCCGACGCAACCGCTGCTCCCATCACCGTCGCATCGGGCCTGACCTCGCCCTCATATGTGGACCAGA
CGCTCACCAACGGCACCACGTACTACTACAAGGTAACGGCCAACGGCGCATCGGGTGCAGACGCGAGCTCGGTCACCGTG
AGCGCGACACCGCATCGGTGA

Upstream 100 bases:

>100_bases
TCCATCGAGAGAAACCACCAGTCACGGAGAATCACGCGACATCTTGATATTTCACTAATTACACACCGTTTCACCATTTC
CCATCTCAAGGCGAAATTCA

Downstream 100 bases:

>100_bases
TGCGATAACTGCGTTGCCACAGAGCGGTAGAGGCTAGTGTGCTCTACCGCTCCTCGGCCGCGGGAGGAGCGCTGCAACCA
CGATGGCGGCGCCTTGCGCC

Product: 1,4-beta-cellobiosidase

Products: NA

Alternate protein names: 1,4-beta-cellobiohydrolase A; CBP95; Exocellobiohydrolase A [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSSSTNLRPCVTSKLAVSLLTGALLVPVAASAQSHVDNPFVGASGYLNPDYSKEVNSSIVKVKDVQLKAKMQVVKSYPTS
VWLDSINAIYGGSRNAGRLSLQGHLDAALAQKKANTPITVGFVIYDMPGRDCHALASNGELPLTQAGLQRYKTEYIDVIA
STLANPKYKDLRIVNIIEPDSLPNLVTNQSTPACGQAASSGIYEAAIKYALDKLHATPNLYNYLDIGHSGWLGWDSNRSP
AISLYTRVVQGTAAGLASADGFITNTANYTPLHEPNLPNPDLTIGGQPIRSSNFYQWNSFFDESTYAEALYNGFVGAGWS
SKIGFLIDTGRNGWGGKARPASASGNDINTYVDSGRVDRRLHRGNWCNQSGAGIGMPPTAAPGGHIHALVWGKGPGESDG
ASKSILNNQGKGFDRYCDPTYTTPDGTLTGALPNAPIAGNWFHAQFLQLVANAYPAIGTSTKAALQSASTDAVPASRPTA
TKGLTANAADGEVRLSWSPVAGATGYTVQRVADATAAPITVASGLTSPSYVDQTLTNGTTYYYKVTANGASGADASSVTV
SATPHR

Sequences:

>Translated_566_residues
MSSSTNLRPCVTSKLAVSLLTGALLVPVAASAQSHVDNPFVGASGYLNPDYSKEVNSSIVKVKDVQLKAKMQVVKSYPTS
VWLDSINAIYGGSRNAGRLSLQGHLDAALAQKKANTPITVGFVIYDMPGRDCHALASNGELPLTQAGLQRYKTEYIDVIA
STLANPKYKDLRIVNIIEPDSLPNLVTNQSTPACGQAASSGIYEAAIKYALDKLHATPNLYNYLDIGHSGWLGWDSNRSP
AISLYTRVVQGTAAGLASADGFITNTANYTPLHEPNLPNPDLTIGGQPIRSSNFYQWNSFFDESTYAEALYNGFVGAGWS
SKIGFLIDTGRNGWGGKARPASASGNDINTYVDSGRVDRRLHRGNWCNQSGAGIGMPPTAAPGGHIHALVWGKGPGESDG
ASKSILNNQGKGFDRYCDPTYTTPDGTLTGALPNAPIAGNWFHAQFLQLVANAYPAIGTSTKAALQSASTDAVPASRPTA
TKGLTANAADGEVRLSWSPVAGATGYTVQRVADATAAPITVASGLTSPSYVDQTLTNGTTYYYKVTANGASGADASSVTV
SATPHR
>Mature_565_residues
SSSTNLRPCVTSKLAVSLLTGALLVPVAASAQSHVDNPFVGASGYLNPDYSKEVNSSIVKVKDVQLKAKMQVVKSYPTSV
WLDSINAIYGGSRNAGRLSLQGHLDAALAQKKANTPITVGFVIYDMPGRDCHALASNGELPLTQAGLQRYKTEYIDVIAS
TLANPKYKDLRIVNIIEPDSLPNLVTNQSTPACGQAASSGIYEAAIKYALDKLHATPNLYNYLDIGHSGWLGWDSNRSPA
ISLYTRVVQGTAAGLASADGFITNTANYTPLHEPNLPNPDLTIGGQPIRSSNFYQWNSFFDESTYAEALYNGFVGAGWSS
KIGFLIDTGRNGWGGKARPASASGNDINTYVDSGRVDRRLHRGNWCNQSGAGIGMPPTAAPGGHIHALVWGKGPGESDGA
SKSILNNQGKGFDRYCDPTYTTPDGTLTGALPNAPIAGNWFHAQFLQLVANAYPAIGTSTKAALQSASTDAVPASRPTAT
KGLTANAADGEVRLSWSPVAGATGYTVQRVADATAAPITVASGLTSPSYVDQTLTNGTTYYYKVTANGASGADASSVTVS
ATPHR

Specific function: This enzyme hydrolyzes 1,4-beta-D-glucosidic linkages of cellulose. Weak activity against carboxymethylcellulose, bacterial microcrystalline cellulose and barley beta-glucan. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion

COG id: COG5297

COG function: function code G; Cellobiohydrolase A (1,4-beta-cellobiosidase A)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 fibronectin type-III domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016288
- InterPro:   IPR008965
- InterPro:   IPR012291
- InterPro:   IPR018366
- InterPro:   IPR001919
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001524
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00553 CBM_2; PF00041 fn3; PF01341 Glyco_hydro_6 [H]

EC number: =3.2.1.91 [H]

Molecular weight: Translated: 59473; Mature: 59341

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS50853 FN3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSTNLRPCVTSKLAVSLLTGALLVPVAASAQSHVDNPFVGASGYLNPDYSKEVNSSIV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHCCCEE
KVKDVQLKAKMQVVKSYPTSVWLDSINAIYGGSRNAGRLSLQGHLDAALAQKKANTPITV
EEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEE
GFVIYDMPGRDCHALASNGELPLTQAGLQRYKTEYIDVIASTLANPKYKDLRIVNIIEPD
EEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
SLPNLVTNQSTPACGQAASSGIYEAAIKYALDKLHATPNLYNYLDIGHSGWLGWDSNRSP
CCCCHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCC
AISLYTRVVQGTAAGLASADGFITNTANYTPLHEPNLPNPDLTIGGQPIRSSNFYQWNSF
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHCC
FDESTYAEALYNGFVGAGWSSKIGFLIDTGRNGWGGKARPASASGNDINTYVDSGRVDRR
CCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHH
LHRGNWCNQSGAGIGMPPTAAPGGHIHALVWGKGPGESDGASKSILNNQGKGFDRYCDPT
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCC
YTTPDGTLTGALPNAPIAGNWFHAQFLQLVANAYPAIGTSTKAALQSASTDAVPASRPTA
CCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCC
TKGLTANAADGEVRLSWSPVAGATGYTVQRVADATAAPITVASGLTSPSYVDQTLTNGTT
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCEE
YYYKVTANGASGADASSVTVSATPHR
EEEEEEECCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SSSTNLRPCVTSKLAVSLLTGALLVPVAASAQSHVDNPFVGASGYLNPDYSKEVNSSIV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHCCCEE
KVKDVQLKAKMQVVKSYPTSVWLDSINAIYGGSRNAGRLSLQGHLDAALAQKKANTPITV
EEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEE
GFVIYDMPGRDCHALASNGELPLTQAGLQRYKTEYIDVIASTLANPKYKDLRIVNIIEPD
EEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
SLPNLVTNQSTPACGQAASSGIYEAAIKYALDKLHATPNLYNYLDIGHSGWLGWDSNRSP
CCCCHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCC
AISLYTRVVQGTAAGLASADGFITNTANYTPLHEPNLPNPDLTIGGQPIRSSNFYQWNSF
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHCC
FDESTYAEALYNGFVGAGWSSKIGFLIDTGRNGWGGKARPASASGNDINTYVDSGRVDRR
CCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHH
LHRGNWCNQSGAGIGMPPTAAPGGHIHALVWGKGPGESDGASKSILNNQGKGFDRYCDPT
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCC
YTTPDGTLTGALPNAPIAGNWFHAQFLQLVANAYPAIGTSTKAALQSASTDAVPASRPTA
CCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCC
TKGLTANAADGEVRLSWSPVAGATGYTVQRVADATAAPITVASGLTSPSYVDQTLTNGTT
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCEE
YYYKVTANGASGADASSVTVSATPHR
EEEEEEECCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8065260; 8458833 [H]