Click here to switch to the map view.

The map label for this gene is prmA

Identifier: 66766863

GI number: 66766863

Start: 619937

End: 620857

Strand: Reverse

Name: prmA

Synonym: XC_0524

Alternate gene names: 66766863

Gene position: 620857-619937 (Counterclockwise)

Preceding gene: 66766866

Following gene: 66766861

Centisome position: 12.06

GC content: 68.4

Gene sequence:

>921_bases
ATGCCGTTCCTTGAATTGACCCTGCCCTGCACCCGCGCCACCCAGCCCCGTTTCGAGAACGCGCTGGAAGATGTGGGCGC
CTTGGCCGTGACCATGCTCGATGCCCATGCCGGCACCATCAACGAGCGCGCCATCCTTGAGCCGGGCGTGGGCGAGGTGC
GGTTGTGGGAGGAGACAGAGCTCACCGCGCTGTTCGACGGCGACAGCGACCCGCTGATGCTGCTGGCCGCGCTGGAAGCC
TTCGACCCGAGCCTGGACACGCGCCATGCGACGTTTCGCAGCGTGGAAGACAGCGCCTGGGAACGGGCCTGGATCGACCA
GTTCAAGCCGATGCGCTTTGGCGCGCGCACCTTCATCGTGCCGTGGAATCAGGACCTGCCCGAAGAGGCCAACACGCCCG
ACGCGGCGGTGGTGCGGCTGGATCCGGGCCTGGCGTTCGGCTCGGGCACCCACCAGACCACCGCGCTGTGCCTGCGCTGG
CTGGATGCGCTGGCCGGCGAGGGCCAGTTGCAGGGCTGCAGCGTGCTGGATTTCGGCTGCGGATCCGGCATCCTGGCCCT
GGCCGCGCTCAAGCTCGGTGCGGCCAACGCGGTGGGCGTGGATTACGACCCGCAAGCGTTGCTGGCCACGGCCGAAAATG
CCGAGCGCAATGCGATGGAAGCGCAAATGCAGGTGTACCTGCCGCAGGACGAACCCGTGCAGACCTACCCGGTGGTGCTG
GCCAATATCCTGGCCACCGCACTGGACGCGCTGGCCGAGACCCTGGCCGCGCGCGTGGCGCCCGGCGGGCGCATTGCGCT
GTCGGGCATCATGCAGGGCCAGGAGCAGGACCTGGTGCAGCGCTACACGCCCTGGTTCGAGCACCTGCACTGCGAATACG
ACGCGGAATGGGTACGCATCGACGGCGTTCGCCGCCACTGA

Upstream 100 bases:

>100_bases
GCGTTTCCCAGCGTAGGCGATGGGCCGTGCTGCCACGCGCCGCTCAGGGCGTGGCGCGCGAATCGTCTACGATGCACGTT
TTACCGCCGCGACCGTCCCG

Downstream 100 bases:

>100_bases
CTCACTCCGGCCGAAGTTCACCGCTGCGGATTCGCGCGGTGGTGACGGCATCCTCGACACTGATGGCGCGCAGCTGGGTC
ACCGGCTGCCAGCCAGCACG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPFLELTLPCTRATQPRFENALEDVGALAVTMLDAHAGTINERAILEPGVGEVRLWEETELTALFDGDSDPLMLLAALEA
FDPSLDTRHATFRSVEDSAWERAWIDQFKPMRFGARTFIVPWNQDLPEEANTPDAAVVRLDPGLAFGSGTHQTTALCLRW
LDALAGEGQLQGCSVLDFGCGSGILALAALKLGAANAVGVDYDPQALLATAENAERNAMEAQMQVYLPQDEPVQTYPVVL
ANILATALDALAETLAARVAPGGRIALSGIMQGQEQDLVQRYTPWFEHLHCEYDAEWVRIDGVRRH

Sequences:

>Translated_306_residues
MPFLELTLPCTRATQPRFENALEDVGALAVTMLDAHAGTINERAILEPGVGEVRLWEETELTALFDGDSDPLMLLAALEA
FDPSLDTRHATFRSVEDSAWERAWIDQFKPMRFGARTFIVPWNQDLPEEANTPDAAVVRLDPGLAFGSGTHQTTALCLRW
LDALAGEGQLQGCSVLDFGCGSGILALAALKLGAANAVGVDYDPQALLATAENAERNAMEAQMQVYLPQDEPVQTYPVVL
ANILATALDALAETLAARVAPGGRIALSGIMQGQEQDLVQRYTPWFEHLHCEYDAEWVRIDGVRRH
>Mature_305_residues
PFLELTLPCTRATQPRFENALEDVGALAVTMLDAHAGTINERAILEPGVGEVRLWEETELTALFDGDSDPLMLLAALEAF
DPSLDTRHATFRSVEDSAWERAWIDQFKPMRFGARTFIVPWNQDLPEEANTPDAAVVRLDPGLAFGSGTHQTTALCLRWL
DALAGEGQLQGCSVLDFGCGSGILALAALKLGAANAVGVDYDPQALLATAENAERNAMEAQMQVYLPQDEPVQTYPVVLA
NILATALDALAETLAARVAPGGRIALSGIMQGQEQDLVQRYTPWFEHLHCEYDAEWVRIDGVRRH

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=307, Percent_Identity=43.9739413680782, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_XANC8 (Q4UZB8)

Other databases:

- EMBL:   CP000050
- RefSeq:   YP_241625.1
- ProteinModelPortal:   Q4UZB8
- SMR:   Q4UZB8
- STRING:   Q4UZB8
- GeneID:   3381532
- GenomeReviews:   CP000050_GR
- KEGG:   xcb:XC_0524
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q4UZB8
- ProtClustDB:   PRK00517
- BioCyc:   XCAM314565:XC_0524-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33398; Mature: 33267

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLELTLPCTRATQPRFENALEDVGALAVTMLDAHAGTINERAILEPGVGEVRLWEETE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCC
LTALFDGDSDPLMLLAALEAFDPSLDTRHATFRSVEDSAWERAWIDQFKPMRFGARTFIV
EEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCEEEEE
PWNQDLPEEANTPDAAVVRLDPGLAFGSGTHQTTALCLRWLDALAGEGQLQGCSVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
GSGILALAALKLGAANAVGVDYDPQALLATAENAERNAMEAQMQVYLPQDEPVQTYPVVL
CCHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCHHHHHEEEEEEECCCCCCCHHHHHHH
ANILATALDALAETLAARVAPGGRIALSGIMQGQEQDLVQRYTPWFEHLHCEYDAEWVRI
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCHHHHHHHHCHHHHHEECCCCCCEEEE
DGVRRH
CCCCCC
>Mature Secondary Structure 
PFLELTLPCTRATQPRFENALEDVGALAVTMLDAHAGTINERAILEPGVGEVRLWEETE
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCC
LTALFDGDSDPLMLLAALEAFDPSLDTRHATFRSVEDSAWERAWIDQFKPMRFGARTFIV
EEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCEEEEE
PWNQDLPEEANTPDAAVVRLDPGLAFGSGTHQTTALCLRWLDALAGEGQLQGCSVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
GSGILALAALKLGAANAVGVDYDPQALLATAENAERNAMEAQMQVYLPQDEPVQTYPVVL
CCHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCHHHHHEEEEEEECCCCCCCHHHHHHH
ANILATALDALAETLAARVAPGGRIALSGIMQGQEQDLVQRYTPWFEHLHCEYDAEWVRI
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCHHHHHHHHCHHHHHEECCCCCCEEEE
DGVRRH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA