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The map label for this gene is hemH [H]

Identifier: 66766806

GI number: 66766806

Start: 553966

End: 554898

Strand: Reverse

Name: hemH [H]

Synonym: XC_0467

Alternate gene names: 66766806

Gene position: 554898-553966 (Counterclockwise)

Preceding gene: 77761086

Following gene: 66766804

Centisome position: 10.78

GC content: 64.52

Gene sequence:

>933_bases
GTGCCTGTGTCGACCACGCTGTTGCAATCCGATCTCCCCGGCCTGCCGTTGCGCCACCGTGGCAAGGTCCGCGATGTCTT
CGACATTCCCCGCGACCGCCTGCCCGCCGATGCGCCCCCCGGCGACTATCTGTTGATGGTGGCCACCGACCGCCTGTCTG
CGTTCGACGTGGTGCTGCCCGACCCGATTCCCGGCAAGGGCGAAATGCTCTGCCAGGTGTCCAACTTCTGGTTCCACAAG
ACCGAACACCTGATGCCCAACCATCTGGTGGACATCCGCGTCGAGCAGGTGCTGCCTGAGGGCGTGGATCCGGCGCTGTA
CGCCAAGCGCGCGGTGGTCACGCGCAAGCTCAAGCCGGTGCCGGTGGAAGCGATCGCACGCGGCTATCTGATCGGCAGCG
GCTGGAAGGACTATCAGCGCACCGGCAAGATCAGCGGCATCGAATTGCCCGATGGCCTGCGCCAGGCCGAGAAACTACCC
GAGCCGATCTTTACCCCTTCGACCAAGGCTGCGGTCGGCGACCATGACGAGAACATCGACTTCGATGCGATGGTCAAGAC
CGTCGGCGCCGAGCTGGCCGAGCGCGTGCGCGATGCCACCTTGCGCATCTATCGTTTCGCCGCCGATTTTGCCGCCGAAC
GCGGCATTTTGCTGGCCGACACCAAGTTCGAATTCGGCACCGACGCCGATGGCCGCCTGTACATCATGGACGAGATGCTG
ACCCCGGATTCGTCGCGCTATTGGCCCGCCGACCAGTACGAGCTGGGCACCAGCCCGCCGAGCTACGACAAGCAGTTCGT
GCGCGATTATCTGGAGACGCTGGACTGGGGCAAGACCGCACCGGGCCCGCGCCTGCCGGCGGATGTAATCGAACGCACGC
GTGCGAAATATGCCGAGGCGTTGCAGAGGCTGGCGGGTATTTCGGTCGATTGA

Upstream 100 bases:

>100_bases
GTGCAGCGGGGCGCCGCGAAGCACCGTACACTACGCGGCCCGCTGCCTACCCGCGGGCCCGCCGGGTCCTGGGGACAGCG
TCATTGCGACGTCCTTAGGA

Downstream 100 bases:

>100_bases
TTCAAGGCCCCACTCCCGAGGCTTTGAGGCTGTACTAAAGCAGCAATGGCGGGCAGCGCTCTTTCTTGAGCGCTGAAGGA
CGCACCTGACGAGATCTGTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHK
TEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLP
EPIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEML
TPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEALQRLAGISVD

Sequences:

>Translated_310_residues
MPVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHK
TEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLP
EPIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEML
TPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEALQRLAGISVD
>Mature_309_residues
PVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKT
EHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLPE
PIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLT
PDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEALQRLAGISVD

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=311, Percent_Identity=43.4083601286174, Blast_Score=257, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 34634; Mature: 34503

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLP
CCCCHHHHHCCCCCCCCCCCCCCCHHHHCCHHCCCCCCCCCCEEEEEECCCCCEEEEECC
DPIPGKGEMLCQVSNFWFHKTEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPV
CCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENID
CHHHHHCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCC
TPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQRLAGISVD
HHHHHCCCCC
>Mature Secondary Structure 
PVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLP
CCCHHHHHCCCCCCCCCCCCCCCHHHHCCHHCCCCCCCCCCEEEEEECCCCCEEEEECC
DPIPGKGEMLCQVSNFWFHKTEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPV
CCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENID
CHHHHHCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCC
TPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQRLAGISVD
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA