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The map label for this gene is glpR [H]

Identifier: 66766716

GI number: 66766716

Start: 434691

End: 435470

Strand: Reverse

Name: glpR [H]

Synonym: XC_0373

Alternate gene names: 66766716

Gene position: 435470-434691 (Counterclockwise)

Preceding gene: 66766717

Following gene: 66766715

Centisome position: 8.46

GC content: 67.82

Gene sequence:

>780_bases
GTGCCGGCGCCGGCACTCAATCCGCGCCAAGAGCAGTTGGTGGCCTTGGTGCGTCAACAGGGCTTTGCCGATGTCGAAGG
GCTGGCGACGCGCTTTGAGGTCACGCCGCAGACCATTCGCCGCGATCTAACCTTGCTCTGCGATGCCGGCGTGCTGCGCC
GGTATCACGGCGGCGTCAGCATGCCGTCCAGCGTGGAGAACCTGGCGTATGCGGCGCGCAAGGCGCTGCAGGCGCGCGAG
AAGCAGCAGATCGCCACGCAGGTGGCGCGCTTCATTCCCGACGACGCCTCGCTGTTCATCAATCTCGGCACCACCAACGA
GGAAGTGGCGCGCGCCTTGCTGCAGCACCGCGGCCTGCGCGTGATCACCAACAACCTCAACGTGGCGGTGATGCTCAGCG
CCAATCCCAGCTTCGAGGTGATCGTGGCCGGCGGCGTGGTGCGTGGCCGGGACCAGGGCGTCACCGGCGAGGCGACCGTG
GAGCTCATCCGCCAGTTCAAGGTGGACTTCGGGGTGATCGGCATTTCCGGGGTCGACCTGGACGGCACGCTGCTGGATTT
CGATTACCAGGAAGTGCGCGTGGCCCAGGCGATCATCGAGCATTCTCGGCAGGTGCTGCTGGCCGCCGACCACAGCAAGT
TCGGCCGCAACGCGATGGTGCGGCTGGGGGCGATTGCACAGGTGCACGACTGGTTCACCGACCGGCCGCCGCCGGAGGAG
CTGCGCACGGTGCTGGCCGAGGCTGGCACGCGCGTGCATCTGGCCGGCGTCGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGTGGTCGCTCTGGCCCAGCGCGGCGCGGCCATGCTCGTGCTTGCATCCTCACGCGCATGGGCGATGATCTGCGCATGG
AGTCGACTCATTACAGGACC

Downstream 100 bases:

>100_bases
CTCCCGCGCTTGAGGGCTGGGCGGCCGGAGCCGCAGGGCTTGTCCCGGCGGTCCAGCAGGCGGCTGATGTACGTGGTGCT
GTTCGGCATACAGCGGGGCT

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MPAPALNPRQEQLVALVRQQGFADVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYAARKALQARE
KQQIATQVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATV
ELIRQFKVDFGVIGISGVDLDGTLLDFDYQEVRVAQAIIEHSRQVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPEE
LRTVLAEAGTRVHLAGVAG

Sequences:

>Translated_259_residues
MPAPALNPRQEQLVALVRQQGFADVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYAARKALQARE
KQQIATQVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATV
ELIRQFKVDFGVIGISGVDLDGTLLDFDYQEVRVAQAIIEHSRQVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPEE
LRTVLAEAGTRVHLAGVAG
>Mature_258_residues
PAPALNPRQEQLVALVRQQGFADVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYAARKALQAREK
QQIATQVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVE
LIRQFKVDFGVIGISGVDLDGTLLDFDYQEVRVAQAIIEHSRQVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPEEL
RTVLAEAGTRVHLAGVAG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=51.0121457489879, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI87082344, Length=242, Percent_Identity=41.7355371900826, Blast_Score=216, Evalue=9e-58,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=30.6034482758621, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=28.3464566929134, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789519, Length=258, Percent_Identity=26.3565891472868, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=27.4678111587983, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=26.4, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=29.004329004329, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=22.8813559322034, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787063, Length=237, Percent_Identity=23.6286919831224, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28207; Mature: 28075

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPALNPRQEQLVALVRQQGFADVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVS
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCC
MPSSVENLAYAARKALQAREKQQIATQVARFIPDDASLFINLGTTNEEVARALLQHRGLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCE
VITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGVDL
EEECCCCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCC
DGTLLDFDYQEVRVAQAIIEHSRQVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPEE
CCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
LRTVLAEAGTRVHLAGVAG
HHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
PAPALNPRQEQLVALVRQQGFADVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVS
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCC
MPSSVENLAYAARKALQAREKQQIATQVARFIPDDASLFINLGTTNEEVARALLQHRGLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCE
VITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGVDL
EEECCCCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCC
DGTLLDFDYQEVRVAQAIIEHSRQVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPEE
CCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
LRTVLAEAGTRVHLAGVAG
HHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]