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The map label for this gene is glpD [H]

Identifier: 66766715

GI number: 66766715

Start: 432816

End: 434342

Strand: Reverse

Name: glpD [H]

Synonym: XC_0372

Alternate gene names: 66766715

Gene position: 434342-432816 (Counterclockwise)

Preceding gene: 66766716

Following gene: 66766714

Centisome position: 8.44

GC content: 67.78

Gene sequence:

>1527_bases
ATGGGCGAGACATACGATCTTCTGGTAATCGGCGGCGGCATCAACGGGGTCGGCATTGCCCGTGACGCGGCCGGGCGCGG
TCTGTCGGTGTGCCTGTGCGAACAGGACGACCTGGCCGCGCATACCAGCAGCGCCAGCACCAAGCTCATCCACGGTGGCC
TGCGCTATCTGGAGCAGTACGAGTTCGCATTGGTCGGCAAGGCGCTGGCCGAACGCGAGGTACTGCTGCGGCTAGCGCCG
CACATCATCTGGCCGCTGCGCTTCCTGCTGCCGCATCAGCCGCATCTGCGCCCGGCCTGGATGATTCGCGCCGGGCTGTT
CCTGTACGACCATCTTGGCGGCAGCAAGCGCAGCCTGCCGCGCTCGCGCCGGCTGTCGCTGCGCACCCATCCGGTTGGCC
AGCCGCTGCAGGAGTCGCTGCGCACCGGCTTTGTGTATTCCGACGCATGGGTGCAGGACGCGCGGTTGGTGGTGCTCAAC
GCGATGGATGCGGCCAAGCGTGGCGCGCAGATCCATACGCGTACGCGTTGCGTTGGCGCCTGGCGCGATGCCGGGTTCTG
GTATGCGGAGCTGGAAGGCTGCGACGGACGCCGCCGCACCGTGCAGTCGCGTGCGCTGGCCAATGCGGCCGGTCCGTGGG
CGGTGTCGTTCCTGGACAAGGTGGCCGCGGTGCCGCACCAGCATGCGCTGCGCCTGGTCAAGGGCAGCCACATCGTGGTG
CCCAAGCTGTTCGACCACGACCACGCGTACATCTTCCAGCAACCCGACCGGCGCATCGTGTTTGCCATTCCCTACGAGCA
CGACTTCACCTTGATCGGCACCACCGACGTGGATTACGAGGCCGACCCGTCCGCACCCAAGATCGACGCGGCCGAGGTGC
AGTACCTGTGCGATGCGGTGAACTTGTATTTCCAGCAGCAGATCACCCCGCAGGATGTGGTGTGGAACTACAGCGGGGTG
CGTCCGCTACTCGACGACGCCGAAGACAACGCCGCCGAAGTGACCCGCGACTATCAGCTGGAAGTGCTCACCGACGGCGC
GCCGCTGCTCAACGTGTTCGGCGGCAAGCTCACCACCTACCGCAAGCTCGCCGAAGAAGCCGTCGACCGGCTGACCCAGG
CCCTGGGCGCGCGCAAGCCGGCGTGGACCGCGCGTGGCGAAGCCCTGCCCGGCGGCGAACAACGCGACATCGCCAGCCTG
CTGGAGCGTGTGCGCACTGCGCGTCCCTGGCTGCCGGCGGCCACCGCACAGCGGCTGGTGCGCAACTACGGTACCTGTGC
CGAGCAGCTGCTTGGCGATGCGCAGGACATGGCTGCACTCGGCCAGCATTTTGGTGCGGACCTCTACCAGGCCGAGGTGG
ATTACCTGTGCGCCCGCGAATGGGCGCAGACCGCCGACGACATCCTGTGGCGCCGCAGCAAACTGGGCCTGCGTGTAGAT
GCCGAGGCGCGCGCGCGCCTGGAGGCGTATCTGCAGACGCGGCCAGCTGCGCACGCCAACGCGCAGACGCACGTGGTCCC
GGCCTGA

Upstream 100 bases:

>100_bases
ACATACGCCTCTTCACGCCTCCGCAAGGCGTCATGTTCGAATATGTTCGAACATGACAACTTAGGTTCGCGCTTGCGGGC
GAGCCGGGACGGAGGCACCG

Downstream 100 bases:

>100_bases
CAGCGTGACTGACGTTGCCAACGAGGAAGGGTCGTTGGCAACGTATCCTGGCGCGCGCGCCGCGCATCATCATGGGTATT
TCGTGGAGGGCAACTGAGAT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MGETYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAP
HIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGQPLQESLRTGFVYSDAWVQDARLVVLN
AMDAAKRGAQIHTRTRCVGAWRDAGFWYAELEGCDGRRRTVQSRALANAAGPWAVSFLDKVAAVPHQHALRLVKGSHIVV
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPSAPKIDAAEVQYLCDAVNLYFQQQITPQDVVWNYSGV
RPLLDDAEDNAAEVTRDYQLEVLTDGAPLLNVFGGKLTTYRKLAEEAVDRLTQALGARKPAWTARGEALPGGEQRDIASL
LERVRTARPWLPAATAQRLVRNYGTCAEQLLGDAQDMAALGQHFGADLYQAEVDYLCAREWAQTADDILWRRSKLGLRVD
AEARARLEAYLQTRPAAHANAQTHVVPA

Sequences:

>Translated_508_residues
MGETYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAP
HIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGQPLQESLRTGFVYSDAWVQDARLVVLN
AMDAAKRGAQIHTRTRCVGAWRDAGFWYAELEGCDGRRRTVQSRALANAAGPWAVSFLDKVAAVPHQHALRLVKGSHIVV
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPSAPKIDAAEVQYLCDAVNLYFQQQITPQDVVWNYSGV
RPLLDDAEDNAAEVTRDYQLEVLTDGAPLLNVFGGKLTTYRKLAEEAVDRLTQALGARKPAWTARGEALPGGEQRDIASL
LERVRTARPWLPAATAQRLVRNYGTCAEQLLGDAQDMAALGQHFGADLYQAEVDYLCAREWAQTADDILWRRSKLGLRVD
AEARARLEAYLQTRPAAHANAQTHVVPA
>Mature_507_residues
GETYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAPH
IIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGQPLQESLRTGFVYSDAWVQDARLVVLNA
MDAAKRGAQIHTRTRCVGAWRDAGFWYAELEGCDGRRRTVQSRALANAAGPWAVSFLDKVAAVPHQHALRLVKGSHIVVP
KLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPSAPKIDAAEVQYLCDAVNLYFQQQITPQDVVWNYSGVR
PLLDDAEDNAAEVTRDYQLEVLTDGAPLLNVFGGKLTTYRKLAEEAVDRLTQALGARKPAWTARGEALPGGEQRDIASLL
ERVRTARPWLPAATAQRLVRNYGTCAEQLLGDAQDMAALGQHFGADLYQAEVDYLCAREWAQTADDILWRRSKLGLRVDA
EARARLEAYLQTRPAAHANAQTHVVPA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=508, Percent_Identity=29.9212598425197, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI285002231, Length=508, Percent_Identity=29.9212598425197, Blast_Score=168, Evalue=1e-41,
Organism=Escherichia coli, GI2367226, Length=493, Percent_Identity=51.7241379310345, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788574, Length=399, Percent_Identity=28.0701754385965, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=512, Percent_Identity=30.6640625, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17509253, Length=512, Percent_Identity=30.078125, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322036, Length=552, Percent_Identity=27.7173913043478, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI161077125, Length=525, Percent_Identity=30.4761904761905, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653942, Length=525, Percent_Identity=30.4761904761905, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653944, Length=525, Percent_Identity=30.4761904761905, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20130025, Length=525, Percent_Identity=30.4761904761905, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24586295, Length=508, Percent_Identity=27.755905511811, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19921278, Length=514, Percent_Identity=26.6536964980545, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45550977, Length=367, Percent_Identity=25.0681198910082, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56425; Mature: 56293

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQY
CCCEEEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHH
EFALVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RSRRLSLRTHPVGQPLQESLRTGFVYSDAWVQDARLVVLNAMDAAKRGAQIHTRTRCVGA
HHHCCEEECCCCCCHHHHHHHHCCEEECCHHCCCEEEEEECHHHHHCCCCEEHHHHHHCC
WRDAGFWYAELEGCDGRRRTVQSRALANAAGPWAVSFLDKVAAVPHQHALRLVKGSHIVV
HHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEE
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPSAPKIDAAEVQYLCDAV
EEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
NLYFQQQITPQDVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVLTDGAPLLNVFGGKLTTY
HHHHHHCCCHHHHEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCHHHHHCCCCHHHH
RKLAEEAVDRLTQALGARKPAWTARGEALPGGEQRDIASLLERVRTARPWLPAATAQRLV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RNYGTCAEQLLGDAQDMAALGQHFGADLYQAEVDYLCAREWAQTADDILWRRSKLGLRVD
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
AEARARLEAYLQTRPAAHANAQTHVVPA
HHHHHHHHHHHHHCCCCCCCCCEEECCC
>Mature Secondary Structure 
GETYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQY
CCEEEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHH
EFALVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RSRRLSLRTHPVGQPLQESLRTGFVYSDAWVQDARLVVLNAMDAAKRGAQIHTRTRCVGA
HHHCCEEECCCCCCHHHHHHHHCCEEECCHHCCCEEEEEECHHHHHCCCCEEHHHHHHCC
WRDAGFWYAELEGCDGRRRTVQSRALANAAGPWAVSFLDKVAAVPHQHALRLVKGSHIVV
HHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEE
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPSAPKIDAAEVQYLCDAV
EEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
NLYFQQQITPQDVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVLTDGAPLLNVFGGKLTTY
HHHHHHCCCHHHHEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCHHHHHCCCCHHHH
RKLAEEAVDRLTQALGARKPAWTARGEALPGGEQRDIASLLERVRTARPWLPAATAQRLV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RNYGTCAEQLLGDAQDMAALGQHFGADLYQAEVDYLCAREWAQTADDILWRRSKLGLRVD
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
AEARARLEAYLQTRPAAHANAQTHVVPA
HHHHHHHHHHHHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]