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The map label for this gene is pycA [H]

Identifier: 66047204

GI number: 66047204

Start: 4724093

End: 4728559

Strand: Direct

Name: pycA [H]

Synonym: Psyr_3977

Alternate gene names: 66047204

Gene position: 4724093-4728559 (Clockwise)

Preceding gene: 66047203

Following gene: 66047205

Centisome position: 77.52

GC content: 62.75

Gene sequence:

>4467_bases
ATGTTCGACAAACTGCTGATCGCCAACCGTGGCGCCATTGCCTGCCGCATCCTGCGGACCCTGCGCACCTTGCAGGTCAA
GGGCGTGGCGGTGTATTCCGAAGCCGACGCTGCCAGCCTGCACCTGATGCAGGCCGACGAAGCCCACAGCCTGGGCGAAG
GTGGCGCAGCCGGAACCTATCTGGCGGTGGACAAGATCCTCGCCATCGCCAACGCCAGCGGCACCAAAGCCATTCATCCC
GGCTACGGTTTTCTCTCCGAAAACGCTGCATTCGCTCAGGCCTGCGAAGACGCCGGTATCGCCTTCGTCGGCCCGACGCC
CGAGCAACTGCGCGTATTCGGCCTCAAGCACACCGCCCGAGCGTTGGCCAAGCAGCATGGCGTGCCCATGCTCGAGGGTA
CTGAACTGCTCGACAGTCTGGAGTCGGCCATCGCGGCAGCCCGCACCATCGGCTACCCGGTGATGCTCAAGAGCACGGCA
GGCGGTGGCGGCATCGGCATGCGTGTGTGTCGCAGTGCCGGAGAGCTGGCTGACTCGTTCGAGGCGGTCAAGCGCCTCGG
TCAGAACAATTTCAGCGATGCGGGTGTGTTCATCGAGAAATACATCCAGCGCGCCCGCCACCTGGAAGTGCAGGTGTTCG
GCGACGGTCAGGGCGAGGTGCTGGCGCTTGGCGTACGCGACTGCTCGGTGCAGCGGCGCAATCAGAAAGTGCTGGAAGAA
ACCCCGGCCCCGAACCTGCCGCACGGCATGGCCGAAGAACTCTGCGCAGCGGCTGTCAAACTCGCCAGGGCAGTCAATTA
TCGCAGCGCCGGGACGGTCGAGTTCGTCTTCGACAGTGAAGATCAGCGCTTCTATTTTCTGGAAGTGAACACACGCTTGC
AGGTCGAGCACGGCGTCACCGAGCAGGTCTGGGGCGTGGATCTGGTCAGCTGGATGGTGCAACTGGCCGCCGGTGATCTG
CCGCCGCTGGATCAGTTGCAGGCCGGTCTGAAACCGCTTGGTCATGCGATTCAGGCGCGGCTGTACGCGGAAGATCCGGG
CCGTGACTTCCAGCCCTGCCCTGGCCTGCTGACTGCGGCTGATTTCCCGCCTGCCGATGGCCGGACGCTGCGCATCGACA
CCTGGGTCGAAGCCGGTTGCGAGATACCGCCGTACTTCGACCCGATGATCGCCAAGCTGATCAGTTGGGCACCGACCCGC
GAGGACGCCAGCGCCGGGCTGATCGACGCGCTGAACGAAACGCGTCTGTACGGTGTGGAAACCAATCGCGACTACTTGCG
CCAGATCATTGCCGACGCGCCGTTCGCCAGTGGCCAGCCATGGACCCGCTGTCTGGAAGATCTGGTGTATCGCGCTGACA
CCTTCGAAGTGCTGAGCGGCGGCACTCAGACCAGCGTTCAGGATTACCCGGGACGACTGGGCTACTGGGCGGTCGGTGTA
CCGCCATCCGGGCCGATGGACAGCCGCGCGTTGCGCCAAGGCAATGAGCTGCTGGGCAACCCCGAAGGATGCGCTGCGCT
GGAAATCACTATGAGCGGGCCGCTACTGCGTTTCAACACCGATGCGGTGGTCGCAGTGACCGGTGCGCACATCCCGATCA
CCCTCGATGGCCAATCCTGTGCGATGAACACCGCGCTATTGGTGAGCGCCGGTTCGACGTTGTCGCTGGGCACCATCGCA
GGTGCCGGTGTACGCAGCTACCTGTGCGTGCGCGGCGGGCTCGACGTGCCGGATTATCTGGGCAGCAAAAGTACCTTTAC
CCTCGGCCAGTTCGGCGGTCATGGCGGTCGCGCGCTGCGCGCCGGCGATGTGCTGCACATCGCGCCCCTGGTGGATCGCC
GTGCAGGGCAGCGGATTGCCGACGAGGCACTTGAAGCGCTGACAGACGTGCGCCGGATGAGGGTCATTTACGGCCCGCAT
GCGGCCCCGGAATACTTCACCGAAGCGTACATCGAGAGGTTTTTCGCGACCGACTGGGAAGTGCATTTCAACTCCAGCCG
CACCGGCGTGCGCCTGATCGGCCCAAAACCCGAATGGGTGCGCGCCGACGGTGGCGAGGCGGGGTTGCACCCTTCCAACA
TTCACGACAACCCGTATGCGATCGGCGCGGTGGATTTCACCGGTGACATGCCGGTAATCCTCGGGCCGGACGGACCCAGC
CTGGGCGGATTCGTCTGCCCGGTGACCATCATCGAGGCAGACCTGTGGCAGCTGGGGCAATTGAAAGCTGGCGACAGGGT
CCGATTCACCCCTGTCAGTGTCGAGGCGTGTCATGCAGAACGATGTGGGAGCGAGCTTGCTCGCGAAGACAGTATTCCTG
ACGCAGAAAATCCATCGACTGTGCCGCCCTCTTCGCGAGCAAGCTCGCTCCCACAAGGCACCGCAAACTCCAGTAGGAAC
GAACTTGTTCGCGAAGGCAGTATTCCTGACGCAGCAAATCCATCGACTGCAACGCCCTCTTCGCGAGCAAGCTCGCTCCC
ACAAGGCACCGCGCGCCTTCAAGGCATCGCAAACTCCCGTAGGAGCGAACTTGTTCGCGAAAACAGTATTCCTGACGCAG
AAACCCCATCGACTGTGCCGACTTCTTCGCGAGCAAGCCAGCTTCCACAAGGCCCGGCAAACTCCCGTGGGAGCAAGCTT
GCTCGCGAAAGCTATATGCCTGACGCAGAAAATCCATCGACTGCAACGCCCTCTTCGCGAGCAAGCTCGCTCCCACAAGG
CCCCGCAAACGCCCGTAGGAGCGAACTTGTTCGCGAAAACAGTATGCCTGACGCAGAAAATCCATTGACTGCACCGCCAT
CTTCGCGAGCAAGCTCGCTCCCACAAGACTCCGCGAACTCCCGTAGGAGCGAGCTTGCTCGCGAAGGCTATATGCCTGAC
GCAGAAAATCCATTGACTACACCTCCCTCTTCGCGAGCAAGCCAGCTTCCACAAGGCCCGGCAAACTCCCGTGGGAGCGA
GCTTGCTCGCGAAGGCTATATTCCTGACGCAGAAAATCCATTGACTGCACCGCCATCTTCGCGAGCAAGCTCGCTCCCAC
AAGGCACCGCGCGCCTTCAAGGCATCGCAAACTCCCGTAGGAGCGAACTTGTTCGCGAAGGCAGTATTCCTGACGCGGAA
AATCCATCGACTGCAACGCCCTCTTCGCGAGCAAGCTCGCTCCCACAAGGCCCCGCAAACTCCAGTAGGAGCGAAGTTGT
TCGCGTAGAGGATCTGCGCACTCCGGTCATCCTCGACATCGGCCAGGACGATAAACGCCTGGTCGCACGTCTGTCCGGCG
ATACCCATCTGCTGCTGGAAATCGGTGCGCCGGAGCTGGATCTGGTGCTGCGCCTGCGTGGCCACGCACTGATGCTTGCG
CTGGAGGCCAAGGCGCTGGCGGGTGTGATCGACCTGACGCCAGGCATTCGCTCGCTGCAAGTCCACTATCGCCCCGAGCA
GCTGCCGCTTCGGCAACTGCTCGACATCGTCGCCGGAGAATGGGACGCGGTGTGCGCCGCGAAAGACCTGCAAGTGGCGT
CGCGCATCGTCCATCTGCCACTGTCCTGGGACGACCCGGCCTGCCAGCTGGCCATCGAAAAATACATGACCACCGTGCGC
AAGGACGCACCGTGGTGCCCAAGCAACCTGGAGTTCATCCGCCGTATCAATGACCTGCCCAACCTCGACGAAGTGCAACG
TACGGTGTTCGACGCCAGTTATCTGGTCATGGGCCTGGGCGATGTGTACCTCGGCGCACCGGTGGCCACGCCGCTGGACC
CGCGCCACCGGCTGGTCACCACCAAGTACAACCCGGCACGCACCTGGACCGCCGAGAATTCGGTGGGCATCGGCGGCGCC
TACATGTGCGTGTATGGCATGGAAGGCCCCGGCGGTTATCAGTTCGTTGGCCGCACGTTGCAGATGTGGAATCGCTATCG
CGACGTCGCCGCCTTCCAGGGCAAACCATGGCTGTTGCGCTTCTTCGATCAGATCCGTTTCTACCCGGTCAGCGCCGAAG
AACTGGTGCGTATCCGCCGCGACTTCCCGCTGGGTCGCTTCGCCCTGAACATCGAACACAGCACCCTGAATCTGGCTGAT
TACCAGGCCTTCCTGAGCCGCGAAGCCGAAGGCATTACGGCATTCCGCGCCCAGCAAAACGCCGCTTTCAACGCCGAGCG
CGAACGCTGGATCGCCAACGGGCAGGCCGATTTCCAGAGCGATGAAGGCGTGGCGCCGAACACTGAAGAACAGCCCCTGC
AACCCGGCCAGCAAGGCGTCGACAGCCACATCGCCGGCAATCTCTGGCAAGTCCAGGTGCAACCGGGAGCGCGCGTGGAA
GCAGGCGATGTGCTGGTGATTCTGGAGTCCATGAAAATGGAAATCCCCCTGCTCGCCCCGATCGCCGGCGTGGTGCAGGA
CGTCAGGGTGCAACCCGGCTCGGCAGTACGCGCAGGGCAACGGGTGGTGGTGCTGAGCGCAGACTGA

Upstream 100 bases:

>100_bases
TGCCCTCAGCAACGGACGACCGTTGCGTAGATTGATCAATAGCGGGACGGCCCGCTTCCCATCACGAAACCGAGTGCGAC
TGGGTTTCCGGGGTTATGCC

Downstream 100 bases:

>100_bases
ATCGAACAACTTTTCACTTTCAAGGGAATCCCGTCATGAACGACACAGCACTGCCCAATGACCTGCGCCTGGACACCGTA
CGCACGGCCTACCAGTCCGG

Product: Urea amidolyase-related protein

Products: NA

Alternate protein names: Pyruvic carboxylase A [H]

Number of amino acids: Translated: 1488; Mature: 1488

Protein sequence:

>1488_residues
MFDKLLIANRGAIACRILRTLRTLQVKGVAVYSEADAASLHLMQADEAHSLGEGGAAGTYLAVDKILAIANASGTKAIHP
GYGFLSENAAFAQACEDAGIAFVGPTPEQLRVFGLKHTARALAKQHGVPMLEGTELLDSLESAIAAARTIGYPVMLKSTA
GGGGIGMRVCRSAGELADSFEAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGQGEVLALGVRDCSVQRRNQKVLEE
TPAPNLPHGMAEELCAAAVKLARAVNYRSAGTVEFVFDSEDQRFYFLEVNTRLQVEHGVTEQVWGVDLVSWMVQLAAGDL
PPLDQLQAGLKPLGHAIQARLYAEDPGRDFQPCPGLLTAADFPPADGRTLRIDTWVEAGCEIPPYFDPMIAKLISWAPTR
EDASAGLIDALNETRLYGVETNRDYLRQIIADAPFASGQPWTRCLEDLVYRADTFEVLSGGTQTSVQDYPGRLGYWAVGV
PPSGPMDSRALRQGNELLGNPEGCAALEITMSGPLLRFNTDAVVAVTGAHIPITLDGQSCAMNTALLVSAGSTLSLGTIA
GAGVRSYLCVRGGLDVPDYLGSKSTFTLGQFGGHGGRALRAGDVLHIAPLVDRRAGQRIADEALEALTDVRRMRVIYGPH
AAPEYFTEAYIERFFATDWEVHFNSSRTGVRLIGPKPEWVRADGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTIIEADLWQLGQLKAGDRVRFTPVSVEACHAERCGSELAREDSIPDAENPSTVPPSSRASSLPQGTANSSRN
ELVREGSIPDAANPSTATPSSRASSLPQGTARLQGIANSRRSELVRENSIPDAETPSTVPTSSRASQLPQGPANSRGSKL
ARESYMPDAENPSTATPSSRASSLPQGPANARRSELVRENSMPDAENPLTAPPSSRASSLPQDSANSRRSELAREGYMPD
AENPLTTPPSSRASQLPQGPANSRGSELAREGYIPDAENPLTAPPSSRASSLPQGTARLQGIANSRRSELVREGSIPDAE
NPSTATPSSRASSLPQGPANSSRSEVVRVEDLRTPVILDIGQDDKRLVARLSGDTHLLLEIGAPELDLVLRLRGHALMLA
LEAKALAGVIDLTPGIRSLQVHYRPEQLPLRQLLDIVAGEWDAVCAAKDLQVASRIVHLPLSWDDPACQLAIEKYMTTVR
KDAPWCPSNLEFIRRINDLPNLDEVQRTVFDASYLVMGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTAENSVGIGGA
YMCVYGMEGPGGYQFVGRTLQMWNRYRDVAAFQGKPWLLRFFDQIRFYPVSAEELVRIRRDFPLGRFALNIEHSTLNLAD
YQAFLSREAEGITAFRAQQNAAFNAERERWIANGQADFQSDEGVAPNTEEQPLQPGQQGVDSHIAGNLWQVQVQPGARVE
AGDVLVILESMKMEIPLLAPIAGVVQDVRVQPGSAVRAGQRVVVLSAD

Sequences:

>Translated_1488_residues
MFDKLLIANRGAIACRILRTLRTLQVKGVAVYSEADAASLHLMQADEAHSLGEGGAAGTYLAVDKILAIANASGTKAIHP
GYGFLSENAAFAQACEDAGIAFVGPTPEQLRVFGLKHTARALAKQHGVPMLEGTELLDSLESAIAAARTIGYPVMLKSTA
GGGGIGMRVCRSAGELADSFEAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGQGEVLALGVRDCSVQRRNQKVLEE
TPAPNLPHGMAEELCAAAVKLARAVNYRSAGTVEFVFDSEDQRFYFLEVNTRLQVEHGVTEQVWGVDLVSWMVQLAAGDL
PPLDQLQAGLKPLGHAIQARLYAEDPGRDFQPCPGLLTAADFPPADGRTLRIDTWVEAGCEIPPYFDPMIAKLISWAPTR
EDASAGLIDALNETRLYGVETNRDYLRQIIADAPFASGQPWTRCLEDLVYRADTFEVLSGGTQTSVQDYPGRLGYWAVGV
PPSGPMDSRALRQGNELLGNPEGCAALEITMSGPLLRFNTDAVVAVTGAHIPITLDGQSCAMNTALLVSAGSTLSLGTIA
GAGVRSYLCVRGGLDVPDYLGSKSTFTLGQFGGHGGRALRAGDVLHIAPLVDRRAGQRIADEALEALTDVRRMRVIYGPH
AAPEYFTEAYIERFFATDWEVHFNSSRTGVRLIGPKPEWVRADGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTIIEADLWQLGQLKAGDRVRFTPVSVEACHAERCGSELAREDSIPDAENPSTVPPSSRASSLPQGTANSSRN
ELVREGSIPDAANPSTATPSSRASSLPQGTARLQGIANSRRSELVRENSIPDAETPSTVPTSSRASQLPQGPANSRGSKL
ARESYMPDAENPSTATPSSRASSLPQGPANARRSELVRENSMPDAENPLTAPPSSRASSLPQDSANSRRSELAREGYMPD
AENPLTTPPSSRASQLPQGPANSRGSELAREGYIPDAENPLTAPPSSRASSLPQGTARLQGIANSRRSELVREGSIPDAE
NPSTATPSSRASSLPQGPANSSRSEVVRVEDLRTPVILDIGQDDKRLVARLSGDTHLLLEIGAPELDLVLRLRGHALMLA
LEAKALAGVIDLTPGIRSLQVHYRPEQLPLRQLLDIVAGEWDAVCAAKDLQVASRIVHLPLSWDDPACQLAIEKYMTTVR
KDAPWCPSNLEFIRRINDLPNLDEVQRTVFDASYLVMGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTAENSVGIGGA
YMCVYGMEGPGGYQFVGRTLQMWNRYRDVAAFQGKPWLLRFFDQIRFYPVSAEELVRIRRDFPLGRFALNIEHSTLNLAD
YQAFLSREAEGITAFRAQQNAAFNAERERWIANGQADFQSDEGVAPNTEEQPLQPGQQGVDSHIAGNLWQVQVQPGARVE
AGDVLVILESMKMEIPLLAPIAGVVQDVRVQPGSAVRAGQRVVVLSAD
>Mature_1488_residues
MFDKLLIANRGAIACRILRTLRTLQVKGVAVYSEADAASLHLMQADEAHSLGEGGAAGTYLAVDKILAIANASGTKAIHP
GYGFLSENAAFAQACEDAGIAFVGPTPEQLRVFGLKHTARALAKQHGVPMLEGTELLDSLESAIAAARTIGYPVMLKSTA
GGGGIGMRVCRSAGELADSFEAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGQGEVLALGVRDCSVQRRNQKVLEE
TPAPNLPHGMAEELCAAAVKLARAVNYRSAGTVEFVFDSEDQRFYFLEVNTRLQVEHGVTEQVWGVDLVSWMVQLAAGDL
PPLDQLQAGLKPLGHAIQARLYAEDPGRDFQPCPGLLTAADFPPADGRTLRIDTWVEAGCEIPPYFDPMIAKLISWAPTR
EDASAGLIDALNETRLYGVETNRDYLRQIIADAPFASGQPWTRCLEDLVYRADTFEVLSGGTQTSVQDYPGRLGYWAVGV
PPSGPMDSRALRQGNELLGNPEGCAALEITMSGPLLRFNTDAVVAVTGAHIPITLDGQSCAMNTALLVSAGSTLSLGTIA
GAGVRSYLCVRGGLDVPDYLGSKSTFTLGQFGGHGGRALRAGDVLHIAPLVDRRAGQRIADEALEALTDVRRMRVIYGPH
AAPEYFTEAYIERFFATDWEVHFNSSRTGVRLIGPKPEWVRADGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTIIEADLWQLGQLKAGDRVRFTPVSVEACHAERCGSELAREDSIPDAENPSTVPPSSRASSLPQGTANSSRN
ELVREGSIPDAANPSTATPSSRASSLPQGTARLQGIANSRRSELVRENSIPDAETPSTVPTSSRASQLPQGPANSRGSKL
ARESYMPDAENPSTATPSSRASSLPQGPANARRSELVRENSMPDAENPLTAPPSSRASSLPQDSANSRRSELAREGYMPD
AENPLTTPPSSRASQLPQGPANSRGSELAREGYIPDAENPLTAPPSSRASSLPQGTARLQGIANSRRSELVREGSIPDAE
NPSTATPSSRASSLPQGPANSSRSEVVRVEDLRTPVILDIGQDDKRLVARLSGDTHLLLEIGAPELDLVLRLRGHALMLA
LEAKALAGVIDLTPGIRSLQVHYRPEQLPLRQLLDIVAGEWDAVCAAKDLQVASRIVHLPLSWDDPACQLAIEKYMTTVR
KDAPWCPSNLEFIRRINDLPNLDEVQRTVFDASYLVMGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTAENSVGIGGA
YMCVYGMEGPGGYQFVGRTLQMWNRYRDVAAFQGKPWLLRFFDQIRFYPVSAEELVRIRRDFPLGRFALNIEHSTLNLAD
YQAFLSREAEGITAFRAQQNAAFNAERERWIANGQADFQSDEGVAPNTEEQPLQPGQQGVDSHIAGNLWQVQVQPGARVE
AGDVLVILESMKMEIPLLAPIAGVVQDVRVQPGSAVRAGQRVVVLSAD

Specific function: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=440, Percent_Identity=47.0454545454545, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI295821183, Length=449, Percent_Identity=42.5389755011136, Blast_Score=342, Evalue=2e-93,
Organism=Homo sapiens, GI65506442, Length=449, Percent_Identity=42.5389755011136, Blast_Score=342, Evalue=2e-93,
Organism=Homo sapiens, GI189095269, Length=449, Percent_Identity=42.5389755011136, Blast_Score=342, Evalue=2e-93,
Organism=Homo sapiens, GI106049528, Length=448, Percent_Identity=41.2946428571429, Blast_Score=328, Evalue=3e-89,
Organism=Homo sapiens, GI106049295, Length=448, Percent_Identity=41.2946428571429, Blast_Score=328, Evalue=3e-89,
Organism=Homo sapiens, GI106049292, Length=448, Percent_Identity=41.2946428571429, Blast_Score=328, Evalue=3e-89,
Organism=Homo sapiens, GI38679960, Length=512, Percent_Identity=30.078125, Blast_Score=205, Evalue=3e-52,
Organism=Homo sapiens, GI38679977, Length=512, Percent_Identity=30.078125, Blast_Score=205, Evalue=3e-52,
Organism=Homo sapiens, GI38679967, Length=512, Percent_Identity=30.078125, Blast_Score=205, Evalue=3e-52,
Organism=Homo sapiens, GI38679971, Length=512, Percent_Identity=30.078125, Blast_Score=205, Evalue=4e-52,
Organism=Homo sapiens, GI38679974, Length=512, Percent_Identity=30.078125, Blast_Score=204, Evalue=4e-52,
Organism=Homo sapiens, GI134142062, Length=515, Percent_Identity=29.9029126213592, Blast_Score=204, Evalue=5e-52,
Organism=Escherichia coli, GI1789654, Length=448, Percent_Identity=43.3035714285714, Blast_Score=328, Evalue=1e-90,
Organism=Escherichia coli, GI1786930, Length=306, Percent_Identity=33.0065359477124, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71987519, Length=446, Percent_Identity=43.4977578475336, Blast_Score=361, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17567343, Length=448, Percent_Identity=42.8571428571429, Blast_Score=336, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17562816, Length=450, Percent_Identity=41.1111111111111, Blast_Score=327, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI133931226, Length=490, Percent_Identity=28.3673469387755, Blast_Score=190, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71997168, Length=516, Percent_Identity=28.1007751937984, Blast_Score=179, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71997163, Length=516, Percent_Identity=28.1007751937984, Blast_Score=178, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319685, Length=797, Percent_Identity=48.1806775407779, Blast_Score=768, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=451, Percent_Identity=40.5764966740577, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6321376, Length=451, Percent_Identity=40.3547671840355, Blast_Score=308, Evalue=6e-84,
Organism=Saccharomyces cerevisiae, GI6324343, Length=526, Percent_Identity=29.0874524714829, Blast_Score=202, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6323863, Length=481, Percent_Identity=29.9376299376299, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24651757, Length=434, Percent_Identity=43.3179723502304, Blast_Score=372, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24651759, Length=398, Percent_Identity=41.9597989949749, Blast_Score=328, Evalue=1e-89,
Organism=Drosophila melanogaster, GI281363050, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652224, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652222, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652220, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652218, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652212, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652210, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652214, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19921944, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24652216, Length=438, Percent_Identity=43.37899543379, Blast_Score=328, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24586458, Length=509, Percent_Identity=29.4695481335953, Blast_Score=197, Evalue=6e-50,
Organism=Drosophila melanogaster, GI161076409, Length=509, Percent_Identity=29.4695481335953, Blast_Score=196, Evalue=8e-50,
Organism=Drosophila melanogaster, GI161076407, Length=509, Percent_Identity=29.4695481335953, Blast_Score=196, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24586460, Length=509, Percent_Identity=29.4695481335953, Blast_Score=196, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004549
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 160132; Mature: 160132

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKLLIANRGAIACRILRTLRTLQVKGVAVYSEADAASLHLMQADEAHSLGEGGAAGTY
CCCCEEEECCCHHHHHHHHHHHHHEECEEEEEECCCCCEEEEEECCCHHCCCCCCCCCHH
LAVDKILAIANASGTKAIHPGYGFLSENAAFAQACEDAGIAFVGPTPEQLRVFGLKHTAR
HHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHEEECHHHHHH
ALAKQHGVPMLEGTELLDSLESAIAAARTIGYPVMLKSTAGGGGIGMRVCRSAGELADSF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
EAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGQGEVLALGVRDCSVQRRNQKVLEE
HHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
TPAPNLPHGMAEELCAAAVKLARAVNYRSAGTVEFVFDSEDQRFYFLEVNTRLQVEHGVT
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCEEEECCCCC
EQVWGVDLVSWMVQLAAGDLPPLDQLQAGLKPLGHAIQARLYAEDPGRDFQPCPGLLTAA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEC
DFPPADGRTLRIDTWVEAGCEIPPYFDPMIAKLISWAPTREDASAGLIDALNETRLYGVE
CCCCCCCCEEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEEE
TNRDYLRQIIADAPFASGQPWTRCLEDLVYRADTFEVLSGGTQTSVQDYPGRLGYWAVGV
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCHHHCCCCCCEEEEEC
PPSGPMDSRALRQGNELLGNPEGCAALEITMSGPLLRFNTDAVVAVTGAHIPITLDGQSC
CCCCCCCHHHHHCCHHHCCCCCCCEEEEEEECCCEEEECCCEEEEEECCEEEEEECCCCH
AMNTALLVSAGSTLSLGTIAGAGVRSYLCVRGGLDVPDYLGSKSTFTLGQFGGHGGRALR
HCCEEEEEECCCCEEEHHHCCCCHHHHHHCCCCCCCHHHCCCCCEEEECCCCCCCCCEEE
AGDVLHIAPLVDRRAGQRIADEALEALTDVRRMRVIYGPHAAPEYFTEAYIERFFATDWE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEE
VHFNSSRTGVRLIGPKPEWVRADGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
EEECCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCC
LGGFVCPVTIIEADLWQLGQLKAGDRVRFTPVSVEACHAERCGSELAREDSIPDAENPST
CCCEECCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPPSSRASSLPQGTANSSRNELVREGSIPDAANPSTATPSSRASSLPQGTARLQGIANSR
CCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
RSELVRENSIPDAETPSTVPTSSRASQLPQGPANSRGSKLARESYMPDAENPSTATPSSR
HHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHH
ASSLPQGPANARRSELVRENSMPDAENPLTAPPSSRASSLPQDSANSRRSELAREGYMPD
HHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCC
AENPLTTPPSSRASQLPQGPANSRGSELAREGYIPDAENPLTAPPSSRASSLPQGTARLQ
CCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHH
GIANSRRSELVREGSIPDAENPSTATPSSRASSLPQGPANSSRSEVVRVEDLRTPVILDI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHEEEEECCCCCEEEEC
GQDDKRLVARLSGDTHLLLEIGAPELDLVLRLRGHALMLALEAKALAGVIDLTPGIRSLQ
CCCHHHHHHHCCCCEEEEEEECCCCEEEHEEECCCEEEEEEEHHHHHHHHCCCCCCCEEE
VHYRPEQLPLRQLLDIVAGEWDAVCAAKDLQVASRIVHLPLSWDDPACQLAIEKYMTTVR
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHH
KDAPWCPSNLEFIRRINDLPNLDEVQRTVFDASYLVMGLGDVYLGAPVATPLDPRHRLVT
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEEE
TKYNPARTWTAENSVGIGGAYMCVYGMEGPGGYQFVGRTLQMWNRYRDVAAFQGKPWLLR
ECCCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FFDQIRFYPVSAEELVRIRRDFPLGRFALNIEHSTLNLADYQAFLSREAEGITAFRAQQN
HHHHHEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHCC
AAFNAERERWIANGQADFQSDEGVAPNTEEQPLQPGQQGVDSHIAGNLWQVQVQPGARVE
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHCCCEEEEEECCCCEEC
AGDVLVILESMKMEIPLLAPIAGVVQDVRVQPGSAVRAGQRVVVLSAD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MFDKLLIANRGAIACRILRTLRTLQVKGVAVYSEADAASLHLMQADEAHSLGEGGAAGTY
CCCCEEEECCCHHHHHHHHHHHHHEECEEEEEECCCCCEEEEEECCCHHCCCCCCCCCHH
LAVDKILAIANASGTKAIHPGYGFLSENAAFAQACEDAGIAFVGPTPEQLRVFGLKHTAR
HHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHEEECHHHHHH
ALAKQHGVPMLEGTELLDSLESAIAAARTIGYPVMLKSTAGGGGIGMRVCRSAGELADSF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
EAVKRLGQNNFSDAGVFIEKYIQRARHLEVQVFGDGQGEVLALGVRDCSVQRRNQKVLEE
HHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
TPAPNLPHGMAEELCAAAVKLARAVNYRSAGTVEFVFDSEDQRFYFLEVNTRLQVEHGVT
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCEEEECCCCC
EQVWGVDLVSWMVQLAAGDLPPLDQLQAGLKPLGHAIQARLYAEDPGRDFQPCPGLLTAA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEC
DFPPADGRTLRIDTWVEAGCEIPPYFDPMIAKLISWAPTREDASAGLIDALNETRLYGVE
CCCCCCCCEEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEEE
TNRDYLRQIIADAPFASGQPWTRCLEDLVYRADTFEVLSGGTQTSVQDYPGRLGYWAVGV
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCHHHCCCCCCEEEEEC
PPSGPMDSRALRQGNELLGNPEGCAALEITMSGPLLRFNTDAVVAVTGAHIPITLDGQSC
CCCCCCCHHHHHCCHHHCCCCCCCEEEEEEECCCEEEECCCEEEEEECCEEEEEECCCCH
AMNTALLVSAGSTLSLGTIAGAGVRSYLCVRGGLDVPDYLGSKSTFTLGQFGGHGGRALR
HCCEEEEEECCCCEEEHHHCCCCHHHHHHCCCCCCCHHHCCCCCEEEECCCCCCCCCEEE
AGDVLHIAPLVDRRAGQRIADEALEALTDVRRMRVIYGPHAAPEYFTEAYIERFFATDWE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEE
VHFNSSRTGVRLIGPKPEWVRADGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
EEECCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCC
LGGFVCPVTIIEADLWQLGQLKAGDRVRFTPVSVEACHAERCGSELAREDSIPDAENPST
CCCEECCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPPSSRASSLPQGTANSSRNELVREGSIPDAANPSTATPSSRASSLPQGTARLQGIANSR
CCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
RSELVRENSIPDAETPSTVPTSSRASQLPQGPANSRGSKLARESYMPDAENPSTATPSSR
HHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHH
ASSLPQGPANARRSELVRENSMPDAENPLTAPPSSRASSLPQDSANSRRSELAREGYMPD
HHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCC
AENPLTTPPSSRASQLPQGPANSRGSELAREGYIPDAENPLTAPPSSRASSLPQGTARLQ
CCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHH
GIANSRRSELVREGSIPDAENPSTATPSSRASSLPQGPANSSRSEVVRVEDLRTPVILDI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHEEEEECCCCCEEEEC
GQDDKRLVARLSGDTHLLLEIGAPELDLVLRLRGHALMLALEAKALAGVIDLTPGIRSLQ
CCCHHHHHHHCCCCEEEEEEECCCCEEEHEEECCCEEEEEEEHHHHHHHHCCCCCCCEEE
VHYRPEQLPLRQLLDIVAGEWDAVCAAKDLQVASRIVHLPLSWDDPACQLAIEKYMTTVR
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHH
KDAPWCPSNLEFIRRINDLPNLDEVQRTVFDASYLVMGLGDVYLGAPVATPLDPRHRLVT
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEEE
TKYNPARTWTAENSVGIGGAYMCVYGMEGPGGYQFVGRTLQMWNRYRDVAAFQGKPWLLR
ECCCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FFDQIRFYPVSAEELVRIRRDFPLGRFALNIEHSTLNLADYQAFLSREAEGITAFRAQQN
HHHHHEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHCC
AAFNAERERWIANGQADFQSDEGVAPNTEEQPLQPGQQGVDSHIAGNLWQVQVQPGARVE
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHCCCEEEEEECCCCEEC
AGDVLVILESMKMEIPLLAPIAGVVQDVRVQPGSAVRAGQRVVVLSAD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 11195096 [H]