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The map label for this gene is tas [H]

Identifier: 66045536

GI number: 66045536

Start: 2668183

End: 2669220

Strand: Direct

Name: tas [H]

Synonym: Psyr_2296

Alternate gene names: 66045536

Gene position: 2668183-2669220 (Clockwise)

Preceding gene: 66045535

Following gene: 66045537

Centisome position: 43.79

GC content: 59.34

Gene sequence:

>1038_bases
ATGCAATTTCGTAAATTGGGCAAAACCGATCTGTCGGTCAGCGCGATCTGTCTGGGCACCATGACCTGGGGCGAGCAGAA
CACCCAGGATGAAGCATTCGAACAGATTCGTATGGCCAAGGATGCCAAGGTCAACTTCCTCGACACGGCAGAAATGTACC
CGGTGCCGCCGCGTGGCGAGACCTACACCAAGACCGAAAGCATCATCGGCGAGTACTTCAAGAAGTACGGCGACCGCAAC
GACTGGGTATTGGCCAGCAAGGTCGCCGGTCCAGGTCGCATGGATCACATCCGCGATGGCAATCCCCGCCTTGACCGCAA
GAACATCACTGCGGCGCTGGAAGCCAGCCTCAAGCGTCTGAACACCGATTATCTGGACCTGTACCAGCTGCACTGGCCGG
ATCGCAAGACCAACTTCTTCGGCGTGCTCGGTTACACCCACGACCCGGATGATCAGGCCGTCGAAATCGAAGAAACCCTG
TCGGTACTGGGCGATCTGGTCAAGGCGGGCAAGATTCGCCACTTCGGTCTGTCCAATGAAACGCCATGGGGCACCCAGCG
TTTTCTGCACCTGGCCGAAACCCTCGATCTGCCACGTGCCGTTTCCATCCAGAACCCCTACAACCTGCTTAACCGCACGT
TTGAAGTCGGTCTGGCGGAAATTGCCATTCGCGAACAGATCGGCCTGCTGGCTTACTCGCCGCTGGCGTTCGGTGTGCTG
GCGGGCAAGTACCTGGACGGTGCACGTCCGGCCGATGGCCGTCTGACCCTGTTCGAGCGTTTCCAGCGCTACAACAATCC
GCAGGCCGTCACCGCCACGGCCAGGTACGTCGCGCTGGCTCGCGAGCATGGTCTGGATCCCTCGCAGATGGCGCTGGCCT
ACGTGACCAGCCGACCGTTCGTGACCAGCAACATCATTGGTGCCACGAAACTCGATCAGCTGAAGATCAATCTGCAGAGC
ATCGACGTCACGCTGTCCGATGAGGTCATCGCCGGTATCGAGGCCATTCACACCTCGCAGCCCAACCCTGCGCCATAA

Upstream 100 bases:

>100_bases
TAGGTAAAACCGGATAAAAAGTGTTGCAGTGAATGACCAGTCGGCGTTTTATGGGAGCCCTGTTTCAAGCTGTATCTTTT
TGAATCAAACGGAGACATCG

Downstream 100 bases:

>100_bases
CCTGCACTGAACTTAATTTCAGCCTCGCCAGTCAGCACTAGTACGCTTACTCCGAGGCTGAAATTGATGCACATCTCACT
CAAGCAACAAGTTGCAATCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MQFRKLGKTDLSVSAICLGTMTWGEQNTQDEAFEQIRMAKDAKVNFLDTAEMYPVPPRGETYTKTESIIGEYFKKYGDRN
DWVLASKVAGPGRMDHIRDGNPRLDRKNITAALEASLKRLNTDYLDLYQLHWPDRKTNFFGVLGYTHDPDDQAVEIEETL
SVLGDLVKAGKIRHFGLSNETPWGTQRFLHLAETLDLPRAVSIQNPYNLLNRTFEVGLAEIAIREQIGLLAYSPLAFGVL
AGKYLDGARPADGRLTLFERFQRYNNPQAVTATARYVALAREHGLDPSQMALAYVTSRPFVTSNIIGATKLDQLKINLQS
IDVTLSDEVIAGIEAIHTSQPNPAP

Sequences:

>Translated_345_residues
MQFRKLGKTDLSVSAICLGTMTWGEQNTQDEAFEQIRMAKDAKVNFLDTAEMYPVPPRGETYTKTESIIGEYFKKYGDRN
DWVLASKVAGPGRMDHIRDGNPRLDRKNITAALEASLKRLNTDYLDLYQLHWPDRKTNFFGVLGYTHDPDDQAVEIEETL
SVLGDLVKAGKIRHFGLSNETPWGTQRFLHLAETLDLPRAVSIQNPYNLLNRTFEVGLAEIAIREQIGLLAYSPLAFGVL
AGKYLDGARPADGRLTLFERFQRYNNPQAVTATARYVALAREHGLDPSQMALAYVTSRPFVTSNIIGATKLDQLKINLQS
IDVTLSDEVIAGIEAIHTSQPNPAP
>Mature_345_residues
MQFRKLGKTDLSVSAICLGTMTWGEQNTQDEAFEQIRMAKDAKVNFLDTAEMYPVPPRGETYTKTESIIGEYFKKYGDRN
DWVLASKVAGPGRMDHIRDGNPRLDRKNITAALEASLKRLNTDYLDLYQLHWPDRKTNFFGVLGYTHDPDDQAVEIEETL
SVLGDLVKAGKIRHFGLSNETPWGTQRFLHLAETLDLPRAVSIQNPYNLLNRTFEVGLAEIAIREQIGLLAYSPLAFGVL
AGKYLDGARPADGRLTLFERFQRYNNPQAVTATARYVALAREHGLDPSQMALAYVTSRPFVTSNIIGATKLDQLKINLQS
IDVTLSDEVIAGIEAIHTSQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=351, Percent_Identity=28.4900284900285, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI4504825, Length=349, Percent_Identity=28.3667621776504, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI27436964, Length=354, Percent_Identity=27.4011299435028, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI27436962, Length=354, Percent_Identity=27.4011299435028, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI27436966, Length=354, Percent_Identity=27.4011299435028, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436971, Length=356, Percent_Identity=25.561797752809, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI41327764, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=53.8904899135447, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI87081735, Length=352, Percent_Identity=30.6818181818182, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789375, Length=342, Percent_Identity=29.8245614035088, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=26.4705882352941, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788081, Length=344, Percent_Identity=27.6162790697674, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=353, Percent_Identity=24.3626062322946, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=313, Percent_Identity=23.6421725239617, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=259, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=234, Percent_Identity=23.5042735042735, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=21.8289085545723, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646155, Length=332, Percent_Identity=26.8072289156627, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38572; Mature: 38572

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFRKLGKTDLSVSAICLGTMTWGEQNTQDEAFEQIRMAKDAKVNFLDTAEMYPVPPRGE
CCCHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TYTKTESIIGEYFKKYGDRNDWVLASKVAGPGRMDHIRDGNPRLDRKNITAALEASLKRL
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NTDYLDLYQLHWPDRKTNFFGVLGYTHDPDDQAVEIEETLSVLGDLVKAGKIRHFGLSNE
CCCHHEEEEEECCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEECCCCC
TPWGTQRFLHLAETLDLPRAVSIQNPYNLLNRTFEVGLAEIAIREQIGLLAYSPLAFGVL
CCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHH
AGKYLDGARPADGRLTLFERFQRYNNPQAVTATARYVALAREHGLDPSQMALAYVTSRPF
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
VTSNIIGATKLDQLKINLQSIDVTLSDEVIAGIEAIHTSQPNPAP
EECCCCCCCCHHHEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQFRKLGKTDLSVSAICLGTMTWGEQNTQDEAFEQIRMAKDAKVNFLDTAEMYPVPPRGE
CCCHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TYTKTESIIGEYFKKYGDRNDWVLASKVAGPGRMDHIRDGNPRLDRKNITAALEASLKRL
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NTDYLDLYQLHWPDRKTNFFGVLGYTHDPDDQAVEIEETLSVLGDLVKAGKIRHFGLSNE
CCCHHEEEEEECCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEECCCCC
TPWGTQRFLHLAETLDLPRAVSIQNPYNLLNRTFEVGLAEIAIREQIGLLAYSPLAFGVL
CCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHH
AGKYLDGARPADGRLTLFERFQRYNNPQAVTATARYVALAREHGLDPSQMALAYVTSRPF
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
VTSNIIGATKLDQLKINLQSIDVTLSDEVIAGIEAIHTSQPNPAP
EECCCCCCCCHHHEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]