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The map label for this gene is nfxB [H]

Identifier: 66045524

GI number: 66045524

Start: 2654958

End: 2655548

Strand: Direct

Name: nfxB [H]

Synonym: Psyr_2284

Alternate gene names: 66045524

Gene position: 2654958-2655548 (Clockwise)

Preceding gene: 66045521

Following gene: 66045525

Centisome position: 43.57

GC content: 61.76

Gene sequence:

>591_bases
ATGCGCCGCCTGCCACTTAGACGAGTTGAAGACGTACCAATGGAATTACCTGCTGACGACAAATTTCTGAAGGCCCTGGC
CGTTGCGCTGGTTGACCATTCCAACGGTACGCTCAAGGATATTGCTCAGGCAGCTGGCGTCAGCAAGGCGACGCTCAACC
GCTTCTGCGGCACCCGCGCCAACCTCGTGGAACTGCTGCTCAATCACGCCTCGGACCTGATGAACCAGATGGTCGCCGAC
GCGGATCTGCAGCATGCTCCGCCGCTGGAAGCGCTTCAGCGGCTGGTCGACAACCACCTCATGCACCGCGAAATGCTGGT
CTTTCTGGTATTCCAGTGGCGCCCGGATTCGCTCGATGAAAGCAGCGGTGGGCGCCGCTGGTTGCCTTACTCCGACGCCC
TCGATGCGTTTTTCCTGCGCGGTCAGCGTGAAGGTCTGTTCCGGATCGACGTCGGTGCCGCTGTCCTTACCGAAATGTTC
GCAGCGCTGCTCTCCGGGATGGTCGACGCCGAACGCCGCGGCCGTGTGGCACGCGTCGGCATGGGCGCTTTGGTGACCCA
GTTTTTCCTGCAGGGCGCGGCGGCACGATAA

Upstream 100 bases:

>100_bases
AATGATCCACTCTGAAAGGCGATGAGTCAATATTGACTCACATGAGGCTTTAGTGACTAATTGTGTATAGGCTTTGAGAA
CGCGGTAAGGTTTCTGCACA

Downstream 100 bases:

>100_bases
GCAGGCCTGTGCTGTTTTGTCGCATGACCTATTGCAGCCCATGAGCGCGACGTTTGCGCGTCTGCTCATGCCTTGATACA
GGATTGGCGGTATTCCCCAT

Product: transcriptional regulatory protein NfxB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRRLPLRRVEDVPMELPADDKFLKALAVALVDHSNGTLKDIAQAAGVSKATLNRFCGTRANLVELLLNHASDLMNQMVAD
ADLQHAPPLEALQRLVDNHLMHREMLVFLVFQWRPDSLDESSGGRRWLPYSDALDAFFLRGQREGLFRIDVGAAVLTEMF
AALLSGMVDAERRGRVARVGMGALVTQFFLQGAAAR

Sequences:

>Translated_196_residues
MRRLPLRRVEDVPMELPADDKFLKALAVALVDHSNGTLKDIAQAAGVSKATLNRFCGTRANLVELLLNHASDLMNQMVAD
ADLQHAPPLEALQRLVDNHLMHREMLVFLVFQWRPDSLDESSGGRRWLPYSDALDAFFLRGQREGLFRIDVGAAVLTEMF
AALLSGMVDAERRGRVARVGMGALVTQFFLQGAAAR
>Mature_196_residues
MRRLPLRRVEDVPMELPADDKFLKALAVALVDHSNGTLKDIAQAAGVSKATLNRFCGTRANLVELLLNHASDLMNQMVAD
ADLQHAPPLEALQRLVDNHLMHREMLVFLVFQWRPDSLDESSGGRRWLPYSDALDAFFLRGQREGLFRIDVGAAVLTEMF
AALLSGMVDAERRGRVARVGMGALVTQFFLQGAAAR

Specific function: Confers resistance to guinolones. May negatively regulate the expression of genes that are associated with cell permeability to drugs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR000843
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR005471 [H]

Pfam domain/function: PF09339 HTH_IclR [H]

EC number: NA

Molecular weight: Translated: 21753; Mature: 21753

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00356 HTH_LACI_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLPLRRVEDVPMELPADDKFLKALAVALVDHSNGTLKDIAQAAGVSKATLNRFCGTRA
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCHH
NLVELLLNHASDLMNQMVADADLQHAPPLEALQRLVDNHLMHREMLVFLVFQWRPDSLDE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSGGRRWLPYSDALDAFFLRGQREGLFRIDVGAAVLTEMFAALLSGMVDAERRGRVARVG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MGALVTQFFLQGAAAR
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRLPLRRVEDVPMELPADDKFLKALAVALVDHSNGTLKDIAQAAGVSKATLNRFCGTRA
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCHH
NLVELLLNHASDLMNQMVADADLQHAPPLEALQRLVDNHLMHREMLVFLVFQWRPDSLDE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSGGRRWLPYSDALDAFFLRGQREGLFRIDVGAAVLTEMFAALLSGMVDAERRGRVARVG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MGALVTQFFLQGAAAR
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1330820; 10984043 [H]