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The map label for this gene is bdlA [H]

Identifier: 66045428

GI number: 66045428

Start: 2542907

End: 2544529

Strand: Direct

Name: bdlA [H]

Synonym: Psyr_2188

Alternate gene names: 66045428

Gene position: 2542907-2544529 (Clockwise)

Preceding gene: 66045427

Following gene: 66045430

Centisome position: 41.73

GC content: 57.36

Gene sequence:

>1623_bases
ATGTTCAGCAAACTCAGTATCTCGCAAAAGCTGTACTTCAGCTTTGCCGCGATCATCCTATTTATCGCCGTTCTGGTCGC
GAGTGCTTACAGAGGCTTTGAGCAGGTCGAAGAGGCAACTAACAGCAATGTCCATACGTATCAGGTACTGAGCGAAGCAC
AACTAGCCCTTGAACAGCTGATCAATATCGAAACCGGGATGCGCGGCTTTGTCATTGCCTCAAAGGATGCGTTTCTGGAG
CCATTGGTGGCGGGGGAGAAGCGCTTCATCGAAGAACTCGATTCGCTCAAGCGTCTGACAGCTGACAATGCGGAACAGCA
GCGCCGCCTGGCTGCTCTGGGTGACACTCAGAAACGCTGGCTTGATGAAGATGTCAATCCGATCATCGCCCTGCGCCGCG
ATCTGACTGCACGCAATATGCCTGATGATCAACTGGATGCACGCATCACCTCGGGTGCCGACAAGGCCAAGATGGACAGC
ATGCGCGCTTTACTTGCCGAGATCAGCGGTGCCGAGCAGAAGTTGCTGGTTCAGCGTAGCCAGGACATGACGGACGCCAA
GCATTTGGCGATCCTGATCCTGATGTGCGGCGGCCTGGCCGCGGCTGTTCTCGCGATGATCCTTGCCGCTGTATTGGGGC
GCAGTACCACGGCGCGTTTGCAACTGGCCATTGATGCCGCAACGGCAATTGCCAATGGCAAGCTGGACACCGTGATCGAT
ACCAGCAGCCACGACGAACTGCCGAAAGCCTTTGATCGTATGCAGAATCGCCTGCGCGAGATGATTCAACAGATCAGCCA
GGCTGCCAATCAGCTGGTCGTTGCCGTACAACAGATTTCCGGTGCGTCCGAGCAACTGTCCGGTGCTATCCAGGAACAGT
CGACGTCCGCCTCGGCGATGGCGGCCACGATCGAAGAGCTGACCGTCAGCATCCATCACGTTTCCGAAAACGCCGACGAG
GCGCATGAACTCGCCAGTCGTTCAGGGCAACAGTCGAAGGACGGTGCGCAGGTCATCGAAAATACCCTGTCCAGCATGAA
TGGCATCGCCCGGACCGTGCAGCTTTCCTCTACTCAGGTCGCAGGCCTGGGTCAGCACTCCGAGCACATTTCATCGATCG
TCAGCGTGATTCAGGGCATTGCCGACCAGACCAACCTGCTGGCCCTCAACGCTGCCATCGAAGCTGCTCGTGCCGGTGAA
CAAGGCCGTGGCTTCGCAGTGGTTGCCGACGAAGTGCGCCTGCTGGCGCAGAACACCGGCAAGTCCACCAAGGAAATCGC
CGGGATGATCGAGAAAATTCAGGCGGGTGTACGGGAAACCGTCGAGAGCATGCGTAGCGGCGTTCAGGAAGTGAACGAAG
GCGTCGAAATGGCGGGCACCGCCGGTCAAGCGATCATCGAGATTCGCGACAGTTCGGGCAAGGTTCTGCAAGTGGTCGAC
CAGATATCCTTCGCACTGCGTGAGCAAACCGCAGCGAGCCAGGATGTCGCACGTAACGTCGAGCGCTCCGCGCAAATGGC
TGAACAGAACAACATTTCGGTTCAGGAATTGCTCAAGACCAGCGGCGGCCTGAAGAACCTCGCTACCAGCCTGCAGACGG
AAGTGGGAAAGTTTCGGCTTTAA

Upstream 100 bases:

>100_bases
TCTCAATGACATCAATCATAAAAGTTGGTTCATCCCCATTTTTACGAGTGATAGCGCCCATCATGCAAGCCATGGAACGG
CTATGTTCAGGATCGACATC

Downstream 100 bases:

>100_bases
GGTCTGAAGACACATCTCGTCAGCAGGATCACCCTGCTGAAACCCCCGGTATTAGTCGAAGCGCTGATACCGGTTTTTTT
TGCATATTCAAAAAACGCGC

Product: histidine kinase

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MFSKLSISQKLYFSFAAIILFIAVLVASAYRGFEQVEEATNSNVHTYQVLSEAQLALEQLINIETGMRGFVIASKDAFLE
PLVAGEKRFIEELDSLKRLTADNAEQQRRLAALGDTQKRWLDEDVNPIIALRRDLTARNMPDDQLDARITSGADKAKMDS
MRALLAEISGAEQKLLVQRSQDMTDAKHLAILILMCGGLAAAVLAMILAAVLGRSTTARLQLAIDAATAIANGKLDTVID
TSSHDELPKAFDRMQNRLREMIQQISQAANQLVVAVQQISGASEQLSGAIQEQSTSASAMAATIEELTVSIHHVSENADE
AHELASRSGQQSKDGAQVIENTLSSMNGIARTVQLSSTQVAGLGQHSEHISSIVSVIQGIADQTNLLALNAAIEAARAGE
QGRGFAVVADEVRLLAQNTGKSTKEIAGMIEKIQAGVRETVESMRSGVQEVNEGVEMAGTAGQAIIEIRDSSGKVLQVVD
QISFALREQTAASQDVARNVERSAQMAEQNNISVQELLKTSGGLKNLATSLQTEVGKFRL

Sequences:

>Translated_540_residues
MFSKLSISQKLYFSFAAIILFIAVLVASAYRGFEQVEEATNSNVHTYQVLSEAQLALEQLINIETGMRGFVIASKDAFLE
PLVAGEKRFIEELDSLKRLTADNAEQQRRLAALGDTQKRWLDEDVNPIIALRRDLTARNMPDDQLDARITSGADKAKMDS
MRALLAEISGAEQKLLVQRSQDMTDAKHLAILILMCGGLAAAVLAMILAAVLGRSTTARLQLAIDAATAIANGKLDTVID
TSSHDELPKAFDRMQNRLREMIQQISQAANQLVVAVQQISGASEQLSGAIQEQSTSASAMAATIEELTVSIHHVSENADE
AHELASRSGQQSKDGAQVIENTLSSMNGIARTVQLSSTQVAGLGQHSEHISSIVSVIQGIADQTNLLALNAAIEAARAGE
QGRGFAVVADEVRLLAQNTGKSTKEIAGMIEKIQAGVRETVESMRSGVQEVNEGVEMAGTAGQAIIEIRDSSGKVLQVVD
QISFALREQTAASQDVARNVERSAQMAEQNNISVQELLKTSGGLKNLATSLQTEVGKFRL
>Mature_540_residues
MFSKLSISQKLYFSFAAIILFIAVLVASAYRGFEQVEEATNSNVHTYQVLSEAQLALEQLINIETGMRGFVIASKDAFLE
PLVAGEKRFIEELDSLKRLTADNAEQQRRLAALGDTQKRWLDEDVNPIIALRRDLTARNMPDDQLDARITSGADKAKMDS
MRALLAEISGAEQKLLVQRSQDMTDAKHLAILILMCGGLAAAVLAMILAAVLGRSTTARLQLAIDAATAIANGKLDTVID
TSSHDELPKAFDRMQNRLREMIQQISQAANQLVVAVQQISGASEQLSGAIQEQSTSASAMAATIEELTVSIHHVSENADE
AHELASRSGQQSKDGAQVIENTLSSMNGIARTVQLSSTQVAGLGQHSEHISSIVSVIQGIADQTNLLALNAAIEAARAGE
QGRGFAVVADEVRLLAQNTGKSTKEIAGMIEKIQAGVRETVESMRSGVQEVNEGVEMAGTAGQAIIEIRDSSGKVLQVVD
QISFALREQTAASQDVARNVERSAQMAEQNNISVQELLKTSGGLKNLATSLQTEVGKFRL

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=32.8220858895706, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=32.1022727272727, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788194, Length=315, Percent_Identity=32.6984126984127, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=31.3380281690141, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789453, Length=356, Percent_Identity=26.9662921348315, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 58046; Mature: 58046

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKLSISQKLYFSFAAIILFIAVLVASAYRGFEQVEEATNSNVHTYQVLSEAQLALEQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
INIETGMRGFVIASKDAFLEPLVAGEKRFIEELDSLKRLTADNAEQQRRLAALGDTQKRW
HHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
LDEDVNPIIALRRDLTARNMPDDQLDARITSGADKAKMDSMRALLAEISGAEQKLLVQRS
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
QDMTDAKHLAILILMCGGLAAAVLAMILAAVLGRSTTARLQLAIDAATAIANGKLDTVID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHHHCCCCCCEEEC
TSSHDELPKAFDRMQNRLREMIQQISQAANQLVVAVQQISGASEQLSGAIQEQSTSASAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH
AATIEELTVSIHHVSENADEAHELASRSGQQSKDGAQVIENTLSSMNGIARTVQLSSTQV
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHH
AGLGQHSEHISSIVSVIQGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLAQNTG
HCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCC
KSTKEIAGMIEKIQAGVRETVESMRSGVQEVNEGVEMAGTAGQAIIEIRDSSGKVLQVVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QISFALREQTAASQDVARNVERSAQMAEQNNISVQELLKTSGGLKNLATSLQTEVGKFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSKLSISQKLYFSFAAIILFIAVLVASAYRGFEQVEEATNSNVHTYQVLSEAQLALEQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
INIETGMRGFVIASKDAFLEPLVAGEKRFIEELDSLKRLTADNAEQQRRLAALGDTQKRW
HHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
LDEDVNPIIALRRDLTARNMPDDQLDARITSGADKAKMDSMRALLAEISGAEQKLLVQRS
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
QDMTDAKHLAILILMCGGLAAAVLAMILAAVLGRSTTARLQLAIDAATAIANGKLDTVID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHHHCCCCCCEEEC
TSSHDELPKAFDRMQNRLREMIQQISQAANQLVVAVQQISGASEQLSGAIQEQSTSASAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH
AATIEELTVSIHHVSENADEAHELASRSGQQSKDGAQVIENTLSSMNGIARTVQLSSTQV
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHH
AGLGQHSEHISSIVSVIQGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLAQNTG
HCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCC
KSTKEIAGMIEKIQAGVRETVESMRSGVQEVNEGVEMAGTAGQAIIEIRDSSGKVLQVVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QISFALREQTAASQDVARNVERSAQMAEQNNISVQELLKTSGGLKNLATSLQTEVGKFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]