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The map label for this gene is namA [H]

Identifier: 66045430

GI number: 66045430

Start: 2545124

End: 2546215

Strand: Direct

Name: namA [H]

Synonym: Psyr_2190

Alternate gene names: 66045430

Gene position: 2545124-2546215 (Clockwise)

Preceding gene: 66045428

Following gene: 66045432

Centisome position: 41.77

GC content: 61.26

Gene sequence:

>1092_bases
ATGTCTGCATTGTTCGAACCCTTCAAACTGAAAGACGTCACGCTGCGCAACCGAATCGCCATTCCTCCGATGTGCCAGTA
CTCGGCAACCGAAGGTGTTATCAACGACTGGCACCACGTGCATCTGGCCAGCATGGCACGCGGTGGTGCGGGTCTGTTGG
TGGTCGAAGCTACCGCCGTTGCGCCGGAAGGGCGTATTACCCCCGGTTGCACCGGTATCTGGAATGACGAACAGGCGCAG
GCATTCGTGCCTGTCGTCAAAGCCATCAAGGCCGCAGGGTGCGTACCGGGTATTCAGATTGCTCACGCCGGTCGCAAGGC
CAGCGCCAATCGTCCATGGGAAGGCGATGACCATATCGCGGCGTCCAATTCGCGCGGCTGGGACACCATCGCGCCGTCCG
CCATCGCGTTCGGTGCCAACCTGCCGAAAGTCCCGCGCGCCATGACCCTGGACGATATCGCGCGTGTTCGCCAGAACTTC
GTCGATGCTGCGCGTCGCGCACGCGATGCCGGCTTTGAATGGATCGAGCTGCATTTTGCCCACGGTTATCTGGGGCAGAG
CTTCTTCTCCGAGCACTCCAACCAGCGCACCGATGAGTACGGCGGCAGCTTCGATAACCGTAGCCGTTTCCTGCTGGAAA
CCCTGGCTGCAGTGCGTGAAGTCTGGCCTGAGAACCTGCCGCTGACCGCACGTTTTGGCGTGATCGAATACGACGGTCGC
GACGAGCAGACTCTGGCAGAGTCGATCGAACTGGCGCGCCGCTTCAAGGCTGGCGGGCTGGATCTGTTGAGCGTCAGCGT
CGGTTTCAGCACCCCGGACGCCAACATTCCGTGGGGGCCTGCGTTCATGGGGCCGATCGCCGAGCGTGTGCGTCGTGAGG
CGGACATTCCCGTGACCAGCGCCTGGGGTTTTGGCGAGCCCAAGCTCGCTGAAGAAGCGGTCAAGTCAGGCCAGCTCGAT
CTGGTCTCGATTGGTCGTGCACATCTGGCCGACCCTCATTGGGCCTACTTCGCAGCGAAAGAACTGGGCGTTGAAAAATC
GGCCTGGACCTTGCCTGCACCTTACGCTCACTGGCTTGAACGTTATCGCTGA

Upstream 100 bases:

>100_bases
CGCATGGTGGGGATGATATCAAGGCTTCCGTTTATTGCCATAGTTCGATTACCATCGAACAACTGAAATCAAAAGTCATC
TGGCCTACGGGAGCTTTCCA

Downstream 100 bases:

>100_bases
GTAAGCCTGATCTGAAAGGATGCACTCTTTGGTGGCGCCTACAGTGTATGCATCTTCTCGTCAGATGAAGTGGTGGGAGG
CATTTGCCAACCACCACCCA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSALFEPFKLKDVTLRNRIAIPPMCQYSATEGVINDWHHVHLASMARGGAGLLVVEATAVAPEGRITPGCTGIWNDEQAQ
AFVPVVKAIKAAGCVPGIQIAHAGRKASANRPWEGDDHIAASNSRGWDTIAPSAIAFGANLPKVPRAMTLDDIARVRQNF
VDAARRARDAGFEWIELHFAHGYLGQSFFSEHSNQRTDEYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGR
DEQTLAESIELARRFKAGGLDLLSVSVGFSTPDANIPWGPAFMGPIAERVRREADIPVTSAWGFGEPKLAEEAVKSGQLD
LVSIGRAHLADPHWAYFAAKELGVEKSAWTLPAPYAHWLERYR

Sequences:

>Translated_363_residues
MSALFEPFKLKDVTLRNRIAIPPMCQYSATEGVINDWHHVHLASMARGGAGLLVVEATAVAPEGRITPGCTGIWNDEQAQ
AFVPVVKAIKAAGCVPGIQIAHAGRKASANRPWEGDDHIAASNSRGWDTIAPSAIAFGANLPKVPRAMTLDDIARVRQNF
VDAARRARDAGFEWIELHFAHGYLGQSFFSEHSNQRTDEYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGR
DEQTLAESIELARRFKAGGLDLLSVSVGFSTPDANIPWGPAFMGPIAERVRREADIPVTSAWGFGEPKLAEEAVKSGQLD
LVSIGRAHLADPHWAYFAAKELGVEKSAWTLPAPYAHWLERYR
>Mature_362_residues
SALFEPFKLKDVTLRNRIAIPPMCQYSATEGVINDWHHVHLASMARGGAGLLVVEATAVAPEGRITPGCTGIWNDEQAQA
FVPVVKAIKAAGCVPGIQIAHAGRKASANRPWEGDDHIAASNSRGWDTIAPSAIAFGANLPKVPRAMTLDDIARVRQNFV
DAARRARDAGFEWIELHFAHGYLGQSFFSEHSNQRTDEYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGRD
EQTLAESIELARRFKAGGLDLLSVSVGFSTPDANIPWGPAFMGPIAERVRREADIPVTSAWGFGEPKLAEEAVKSGQLDL
VSIGRAHLADPHWAYFAAKELGVEKSAWTLPAPYAHWLERYR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=348, Percent_Identity=29.0229885057471, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789463, Length=344, Percent_Identity=27.3255813953488, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565138, Length=301, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=270, Percent_Identity=28.1481481481481, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=300, Percent_Identity=26, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=248, Percent_Identity=29.4354838709677, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=302, Percent_Identity=25.8278145695364, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=303, Percent_Identity=25.7425742574257, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=325, Percent_Identity=26.4615384615385, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=238, Percent_Identity=29.8319327731092, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=268, Percent_Identity=30.9701492537313, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39821; Mature: 39690

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFEPFKLKDVTLRNRIAIPPMCQYSATEGVINDWHHVHLASMARGGAGLLVVEATAV
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHCHHHHHHHHHCCCCCCEEEEEEEEE
APEGRITPGCTGIWNDEQAQAFVPVVKAIKAAGCVPGIQIAHAGRKASANRPWEGDDHIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
ASNSRGWDTIAPSAIAFGANLPKVPRAMTLDDIARVRQNFVDAARRARDAGFEWIELHFA
ECCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
HGYLGQSFFSEHSNQRTDEYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGR
HHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECEEEECCC
DEQTLAESIELARRFKAGGLDLLSVSVGFSTPDANIPWGPAFMGPIAERVRREADIPVTS
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEC
AWGFGEPKLAEEAVKSGQLDLVSIGRAHLADPHWAYFAAKELGVEKSAWTLPAPYAHWLE
CCCCCCHHHHHHHHHCCCEEEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RYR
HCC
>Mature Secondary Structure 
SALFEPFKLKDVTLRNRIAIPPMCQYSATEGVINDWHHVHLASMARGGAGLLVVEATAV
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHCHHHHHHHHHCCCCCCEEEEEEEEE
APEGRITPGCTGIWNDEQAQAFVPVVKAIKAAGCVPGIQIAHAGRKASANRPWEGDDHIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
ASNSRGWDTIAPSAIAFGANLPKVPRAMTLDDIARVRQNFVDAARRARDAGFEWIELHFA
ECCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
HGYLGQSFFSEHSNQRTDEYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGR
HHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECEEEECCC
DEQTLAESIELARRFKAGGLDLLSVSVGFSTPDANIPWGPAFMGPIAERVRREADIPVTS
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEC
AWGFGEPKLAEEAVKSGQLDLVSIGRAHLADPHWAYFAAKELGVEKSAWTLPAPYAHWLE
CCCCCCHHHHHHHHHCCCEEEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RYR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA